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Treatment of 140 cerebral palsied children with a combined method based on traditional Chinese medicine(TCM)and western medicine 被引量:1
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作者 周雪娟 郑焜 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE CAS CSCD 2005年第1期57-60,共4页
Objective:To observe and evaluate a method that is effective and practical for treatment of cerebral palsied(CP)children in China.Method:The patient's age and disease type and individual specific conditions were c... Objective:To observe and evaluate a method that is effective and practical for treatment of cerebral palsied(CP)children in China.Method:The patient's age and disease type and individual specific conditions were considered in choosingtherapy methods accordingly:Chinese herbs,acupuncture,auricnlar seed pressure,point finger pressing,massage,orthopedichand manipulation,physiotherapy,occupational therapy,language therapy,etc.Meanwhile we created a new CP treatment modelthat combines hospitalized treatment with family therapy.Results:The majority of CP patients improved greatly in motor andsocial adaptation capacities after treatment.Wilcoxon paired rank sum test analysis showed that there were significant differencesbetween the data before and after treatment(P<0.01).Conclusion:This combined therapy method,based on traditional Chinesemedicine and western medicine plus family supplemental therapy,is an effective and practical treatment strategy for CP children inChina. 展开更多
关键词 traditional chinese medicine(TCM)combined with western medicine therapy Childhood cerebral palsy
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Advances in the management of arteriosclerosis of the lower extremity:Integrating Western and Chinese medicine approaches
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作者 Sha Cheng Jia-Xin Xu Wen-Jie Long 《World Journal of Clinical Cases》 SCIE 2024年第36期6871-6876,共6页
This editorial provides a commentary on the recent article.The paper reviews current literature and explores innovative treatment strategies for lower extremity arteriosclerosis obliterans(LEASO)through an integrative... This editorial provides a commentary on the recent article.The paper reviews current literature and explores innovative treatment strategies for lower extremity arteriosclerosis obliterans(LEASO)through an integrative approach.It highlights the effectiveness of combination therapies that merge traditional Chinese medicine(TCM)with Western medical practices,suggesting that such integrative methods may improve patient compliance and outcomes through personalized care.This paper stresses the importance of rigorous clinical trials to evaluate the efficacy and safety of TCM interventions within LEASO treatment protocols,advocating for evidence-based validation of these combined therapies.Our recommendations emphasize accurate diagnosis,appropriate pharmacological in-terventions,the use of advanced surgical and endovascular techniques,and the inclusion of TCM to address underlying dysfunctions.Additionally,continuous monitoring,patient education,and lifestyle modifications are essential to slow disease progression and achieve optimal patient outcomes.The paper concludes by calling for further research to develop standardized treatment protocols that effectively integrate both Western and Chinese medical approaches in managing LEASO. 展开更多
关键词 Lower extremity arteriosclerosis obliterans traditional chinese medicine Integrative healthcare Vascular therapy Combination therapies
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Tall gastrodis tuber combined with antiepileptic drugs repairs abnormal perfusion foci in focal epilepsy 被引量:2
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作者 Weimin Wang Zhenyu Fan +6 位作者 Yongqin Zhang Yuxia Yang Yaqing Liu Xiaoli Dang Wenjun Song Yinping Wu Jiang Ye 《Neural Regeneration Research》 SCIE CAS CSCD 2013年第3期208-217,共10页
One hundred patients with focal epilepsy were recruited for the present study and their seizures controlled with antiepileptic drugs. The patients then orally received a capsule of tall gastrodis tuber powder, a tradi... One hundred patients with focal epilepsy were recruited for the present study and their seizures controlled with antiepileptic drugs. The patients then orally received a capsule of tall gastrodis tuber powder, a traditional Chinese drug, and underwent single photon emission computed tomography, long-term electroencephalogram, and CT/MRI. Blood drug levels were monitored throughout the study. Before treatment with tall gastrodis tuber, 35 of the 100 cases had abnormal CT/MRI scans; 79 cases had abnormal single photon emission computed tomography images; 86 cases had abnormal electroencephalogram; and a total of 146 abnormal perfusion foci were observed across the 100 subjects. After treatment, the number of patients with normal single photon emission computed tomography images increased by 12; normal electroencephalogram was observed in an additional 27 cases and the number of patients with epileptiform discharge decreased by 29 (34% of 86); the total number of abnormal perfusion foci decreased by 52 (36%) and changes in abnormal loci were visible in 65 patients. These changes indicate that the administration of tall gastrodis tuber in combination with antiepileptic drugs repairs abnormal perfusion foci in patients with focal epilepsy Our results demonstrate that traditional Chinese drugs can repair abnormal perfusion foci and, as such, are a promising new pathway in the treatment of focal epilepsy. 展开更多
关键词 neural regeneration traditional chinese medicine neuroimaging brain injury tall gastrodis tuber antiepileptic drugs combination therapy focal epilepsy abnormal perfusion focus single photonemission computed tomography long-term vigilance-controlled electroencephalogram region ofinterest grant-supported paper photographs-containin^l paper: neuoreaeneration
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Traditional Chinese medicine integrated with chemotherapy for stage Ⅳ non-surgical gastric cancer: a retrospective clinical analysis 被引量:20
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作者 xuan liu li-juan xiu +13 位作者 jian-peng jiao jing zhao ying zhao ye lu jun shi yong-jin li min ye yu-fang gu xiao-wei wang jing-yu xu ci-an zhang yong-ying liu yun luo xiao-qiang yue 《Journal of Integrative Medicine》 SCIE CAS CSCD 2017年第6期469-475,共7页
OBJECTIVE: Traditional Chinese medicine (TCM) is regarded as an important treatment for gastric cancer patients, especially for those in advanced stage. To evaluate the effects of TCM treatment on gastric cancer pa... OBJECTIVE: Traditional Chinese medicine (TCM) is regarded as an important treatment for gastric cancer patients, especially for those in advanced stage. To evaluate the effects of TCM treatment on gastric cancer patients, the authors performed a retrospective study to report the result of the integrated treatment of TCM with chemotherapy for stage IV non-surgical gastric cancer. METHODS: In this study, 182 patients with stage IV and non-surgical gastric cancer were retrospectively analyzed to evaluate the effects of TCM integrated with chemotherapy. Among the 182 cases, 88 cases received integrated therapy consisting of TCM and chemotherapy, while 94 cases received chemotherapy alone. The overall survival and Karnofsky performance status (KPS) score were measured as the main outcome. RESULTS: The median overall survival of the integrated therapy group and chemotherapy group were 16.9 and 10.5 months, respectively. The 1-, 3- and 5-year survival rates of integrated therapy group vs. chemotherapy group were 70% vs. 32%, 18% vs. 4%, and 11% vs. 0%, respectively. There was a significant difference between the two groups (x2 = 42.244, P 〈 0.001 ). After six-month treatment, KPS scores of the integrated therapy group and the chemotherapy group were 75.00 ± 14.78 and 60.64 ± 21.39, respectively (P 〈 0.001). The Cox regression analysis showed that TCM treatment is a protective factor for patients' overall survival. CONCLUSION: This study demonstrated that TCM integrated with chemotherapy may prolong overal survival and improve survival rate and life quality of patients with stage IV non-surgical gastric cancer 展开更多
关键词 stomach neoplasms drug therapy combination medicine chinese traditional integrativemedicine plants medicinal
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Cohort Study on the Effect of a Combined Treatment of Traditional Chinese Medicine and Western Medicine on the Relapse and Metastasis of 222 Patients with Stage Ⅱ and Ⅲ Colorectal Cancer after Radical Operation 被引量:27
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作者 杨宇飞 葛建忠 +8 位作者 吴煜 许云 梁碧颜 雒琳 关显文 刘端祺 张侠 宋飞翔 耿振英 《Chinese Journal of Integrative Medicine》 SCIE CAS 2008年第4期251-256,共6页
Objective: To evaluate the effectiveness of a comprehensive therapy of traditional Chinese medicine (TCM) in reducing the relapse and metastasis of stage Ⅱ and Ⅲ colorectal cancer based on conventional Western me... Objective: To evaluate the effectiveness of a comprehensive therapy of traditional Chinese medicine (TCM) in reducing the relapse and metastasis of stage Ⅱ and Ⅲ colorectal cancer based on conventional Western medicine (WM) therapy. Methods: Two hundred and twenty-two patients in total, diagnosed as stage Ⅱ and Ⅲ colorectal cancer from February 2000 to March 2006, were recruited from Xiyuan Hospital, China Academy of Chinese Medical Sciences and the General Hospital of Beijing Military Area. They were followed-up once every 3-6 months. Twenty cases dropped out from the cohort. The remaining 202 patients were all treated with routine WM treatment [including R0 radical operation, or chemotherapy or/and radiotherapy according to national comprehensive cancer network (NCCN) clinical guidelines]. These patients were assigned to two groups based on whether or not they were additionally treated with TCM comprehensive therapy (orally administered with a decoction according to syndrome differentiation, combined with a traditional patent drug over one year). Ninety-eight patients from Xiyuan Hospital were treated with WM and TCM (combined group), and 104 patients from the General Hospital of Beijing Military Area were treated with WM alone (WM group). The demographic data at baseline were comparable, including the operation times, age, sex, TNM staging, and pathological types. The patients were followed-up for one to five years. Up to now, there are 98, 98, 77, 64, and 47 patients with 1, 2, 3, 4, and 5 years of follow-up in the combined group, respectively; and 104, 104, 97, 81, and 55 patients in the WM group, respectively. The results of the 5-year follow-up of all the patients will be available in 2011. Results: The relapse/metastasis rate of 1-, 2-, 3-, 4-, and 5-year were 0 (0/98), 2.04% (2/98), 11.69% (9/77), 14.06% (9/64), and 21.28% (10/47) in the combined group, and were 4.80%(5/104), 16.35% (17/104), 21.65% (21/97), 25.93% (21/81), and 38.18%(21/55) in the WM group, respectively. A significant difference was found in the second year between the two groups (X^2=12.117, P = 0.000). Median relapse/metastasis time was 26.5 months in the combined group and 16.0 months in the WM group. Conclusion: The combined therapy of TCM and WM may have great clinical value and a potential for decreasing the relapse or metastasis rate in stage Ⅱ and Ⅲ colorectal cancer after conventional WM therapy. 展开更多
关键词 combined therapy of traditional chinese medicine conventional Western medicine therapy colorectal cancer relapse and metastasis cohort study
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Prognostic analysis of transarterial chemoembolization combined with a traditional Chinese herbal medicine formula for treatment of unresectable hepatocellular carcinoma 被引量:5
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作者 YU Yang LANG Qing-bo CHEN Zhe LI Bai YU Chao-qin ZHU De-zeng HUANG Xue-qiang ZHAI Xiao-feng LING Chang-quan 《Chinese Medical Journal》 SCIE CAS CSCD 2009年第17期1990-1995,共6页
Background Transarterial chemoembolization (TACE) is the most widely used primary treatment for unresectable hepatocellular carcinoma (HCC) due to its survival benefit, though its clinical effect is still far from... Background Transarterial chemoembolization (TACE) is the most widely used primary treatment for unresectable hepatocellular carcinoma (HCC) due to its survival benefit, though its clinical effect is still far from satisfactory. Jiedufang (JDF) granule preparation is a commonly used Chinese herbal medicine formula for HCC. The aim of this study was to evaluate the effect of combined therapy with TACE and JDF granule preparation in treatment of unresectable HCC on survival. Methods A retrospective study of TACE was performed in 165 patients with unresectable HCC who were admitted between January 2002 and December 2007 in Changhai Hospital, Shanghai, China. Of the 165 patients, 80 patients (study group) received combined therapy consisting of TACE and a long-term maintenance treatment with oral JDF granule preparation, and the remaining 85 patients (control group) received TACE alone. The survival rates of both groups were calculated by the Kaplan-Meier method. Factors possibly affecting survival were assessed by multivariate analysis in the Cox proportional hazard model, such as maximum tumor size, number of lesions, portal vein invasion, and etc. Results The median overall survival was 9.2 months (95% CI: 6.94-11.46) in the study group versus 5.87 months (95% CI: 4.21-7.52) in the control group. In the study group,survival rates of the 1-, 2- and 3-year follow-up were 41.2%, 18.4%, and 9.6%, respectively. Significant independent prognostic factors identified by the Cox regression analysis were as follows: serum hepatitis B surface antigen (HBsAg) (P=0.014), maximum tumor size (P=0.027), number of lesions (P 〈0.001), portal vein invasion (P 〈0.001), and the therapy model (P=-0.006). Conclusion Combination therapy of TACE and JDF granule preparation may significantly prolong survival of patients with unresectable HCC. 展开更多
关键词 carcinoma hepatocellular chemoembolization therapeutic medicine chinese traditional drug therapy combination prognostic factors
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Comment on the intervention of Traditional Chinese Medicine on survival rates of patients living with human immunodeficiency virus and acquired immune deficiency syndrome 被引量:6
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作者 Li Qiang Liu Zhibin +2 位作者 Yang Jiping Guo Huijun Xu Liran 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2016年第3期409-410,共2页
Despite many differences between Traditional Chinese Medicine(TCM) and conventional medicine,the use of TCM in the treatment of human immunodeficiency virus and acquired immune deficiency syndrome(HIV/AIDS) is increas... Despite many differences between Traditional Chinese Medicine(TCM) and conventional medicine,the use of TCM in the treatment of human immunodeficiency virus and acquired immune deficiency syndrome(HIV/AIDS) is increasingly recognized and accepted by patients. Recent research findings on the benefits of Chinese herbal medicine on long-term survival in patients with HIV/AIDS are encouraging and hopeful, but inconclusive. More research is needed. 展开更多
关键词 HIV Acquired immunodeficiency syndrome medicine chinese traditional Survival rate Combination antiretroviral therapy
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Differential Treatment for Membranoproliferative Glomerulonephritis with TCM Prescriptions Plus Triptoryph Tablets A Report of 30 Cases
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作者 鞠建伟 连业钦 +1 位作者 薄守波 毛树章 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2003年第3期177-179,共3页
Membranoproliferative glomerulonephritis is aglomerulopathy,which accounts for about 30% of thechronic glomerulonephritis in adults.TCMmedication with addition of triptoryph tablets(Tripterygium Wilfordii polyglycosid... Membranoproliferative glomerulonephritis is aglomerulopathy,which accounts for about 30% of thechronic glomerulonephritis in adults.TCMmedication with addition of triptoryph tablets(Tripterygium Wilfordii polyglycosidium) on thebasis of syndrome differentiation had yieldedsatisfactory results in 30 cases of this disease treatedfrom Jan 1998 to Aug 2002.A report follows. 展开更多
关键词 PHYTOtherapy TRIPTERYGIUM ADULT Diagnosis Differential Drug therapy Combination Drugs chinese Herbal Female Glomerulonephritis Membranoproliferative Humans Immunosuppressive Agents Male medicine chinese traditional TABLETS
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CLINICAL OBSERVATION ON TREATMENT OF 80 CASES OF PROLAPSE OF LUMBAR INTERVERTEBRAL DISC BY COMBINATION OF ACUPUNCTURE AND MEDICINE
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作者 阮永队 周伟雄 +1 位作者 郑智 何学武 《World Journal of Acupuncture-Moxibustion》 2002年第2期36-39,共4页
cases of prolapse of lumbar intervetebral disc were randomly divided into treatment and control groups. 80 cases in treatment group were treated with combination of acupuncture, oral administration of Chinese medicina... cases of prolapse of lumbar intervetebral disc were randomly divided into treatment and control groups. 80 cases in treatment group were treated with combination of acupuncture, oral administration of Chinese medicinal herbs, traction, point injection and intravenous drip of energy dehydration mixture; 70 cases in control group were managed by combination of acupuncture, oral administration of herbal medicines, traction, acupoint injection (without energy dehydration mixture). The results showed that the curative rate and the total effective rate of the treatment group were 91.25% and 98.75% separately, while those of the control group 62.86% and 92.86% respectively. Comparison of the curative rate between the 2 groups showed a remarkable significance (P<0.01). The observation demonstrated that combined treatment of prolapse of lumbar intervertebral disc with traditional Chinese and Western medicine is an effective approach. 展开更多
关键词 Prolapse of lumbar intervertebral disc combined therapy of traditional chinese medicine and modern medicine
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A study of acupoint selection rules of moxibustion and auricular point therapy in the treatment of urinary retention after anorectal surgery based on data mining
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作者 Li-Jiang Ji Jing-Yu Xu +4 位作者 Xiao-Jun Yang Lin-Lin Yang Mei-Ling He Min Zhong Jing Gu 《Asian Toxicology Research》 2021年第1期32-38,共7页
Based on the Traditional Chinese Medicine Inheritance Support System(V2.5),we explored the compatibility rules of moxibustion and auricular point prescriptions in the treatment of urinary retention after anorectal sur... Based on the Traditional Chinese Medicine Inheritance Support System(V2.5),we explored the compatibility rules of moxibustion and auricular point prescriptions in the treatment of urinary retention after anorectal surgery,and further to obtain new prescriptions.Methods:We searched CNKI,Wanfang,VIP and CBM databases for the literature of moxibustion and auricular point therapy for urinary retention after anorectal surgery,collecting complete prescriptions and entering them into the Traditional Chinese Medicine Inheritance Support System(V2.5).The acupoint frequency,association rules,and combination rules were analyzed by data mining method of software integration.Results:126 moxibustion prescriptions were selected,and the acupoints for urinary retention after anorectal surgery in the literature were analyzed,including 10 acupoints with frequency≥6,9 acupoint combinations with frequency≥26,5 acupoints with association rules,6 core acupoint combinations and 3 new prescription.124 auricular point prescriptions were selected,and the relevant acupoints in the literature were analyzed,including 10 acupoints with frequency of use≥18,15 acupoint combinations with frequency≥40,12 acupoint combinations with association rules,6 core acupoint combinations,and 3 new prescriptions.The core points include Qihai(RN6),Sanyinjiao(SP6),Zhongji(RN3),Guanyuan(RN4).The auricular point therapy is more to select the tenderness points and acupoints that have an impact on the urinary system,mainly including“Pangguang”(CO9),“Shenmen”(TF4),“Shen”(CO10),“Sanjiao”(CO17),“Pizhixia”(AT4),“Niaodao”(HX3),“Fei”(CO14),“Jiaogan”(AH6a).Conclusion:Moxibustion for the treatment of urinary retention is mainly based on invigorating“Primordial Qi”and regulating the functions of“Middle Jiao”(refers to the area of the body just below the diaphragm and above the navel that helps produce delicate nutrients).The entropic clustering of complex systems excavated new prescriptions for the treatment of urinary retention after anorectal surgery,providing new ideas for future research and treatment. 展开更多
关键词 Urinary retention after anorectal surgery MOXIBUSTION Auricular point therapy Points combination rules traditional chinese medicine Inheritance Support System
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中药脐疗治疗溃疡性结肠炎缓解期疗效观察
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作者 李静 高海波 刘兰香 《中国医药科学》 2024年第15期106-109,共4页
目的观察中药脐疗干预治疗溃疡性结肠炎缓解期临床效果。方法选取2021年1月至2023年3月在潍坊医学院附属高密市人民医院消化内科就诊溃疡性结肠炎缓解期患者,按照随机数表法分为治疗组、对照组,每组各35例。对照组口服美沙拉嗪肠溶片1.0... 目的观察中药脐疗干预治疗溃疡性结肠炎缓解期临床效果。方法选取2021年1月至2023年3月在潍坊医学院附属高密市人民医院消化内科就诊溃疡性结肠炎缓解期患者,按照随机数表法分为治疗组、对照组,每组各35例。对照组口服美沙拉嗪肠溶片1.0 g,tid;治疗组同时给予中药脐疗“十味抗炎方”凝胶剂。采用改良Mayo评分评价溃疡性结肠炎严重程度;溃疡性结肠炎疾病活动指数评价疾病活动度;炎症性肠病生存量表评价生存质量;检查炎症因子白细胞介素-6、白细胞介素-8和肿瘤坏死因子-α;选择抑郁自评量表和焦虑自评量表评价患者心理情况。结果治疗组第5、6个月Mayo评分和疾病活动指数得分低于对照组,差异有统计学意义(P<0.05);治疗组第3、4、5、6个月炎症性肠病生存量表得分高于对照组,差异有统计学意义(P<0.05);治疗组第3、6个月炎症因子低于对照组,差异有统计学意义(P<0.05);治疗组第3、6个月抑郁和焦虑自评量表评分低于对照组,差异有统计学意义(P<0.05)。结论中药脐疗提升患者生活质量,改善预后,临床疗效优于对照组。 展开更多
关键词 溃疡性结肠炎 脐疗 中西医结合 临床研究
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子午流注开穴法预防生长激素激发试验不良反应临床观察
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作者 曹美珠 《中国中医药现代远程教育》 2024年第17期94-96,共3页
目的观察子午流注开穴法预防生长激素(GH)激发试验不良反应的临床疗效。方法选取2021年11月—2022年10月于广州中医药大学顺德医院进行GH激发试验的矮小症儿童80例,随机分为对照组、观察组,各40例。对照组给予常规护理及治疗,观察组在... 目的观察子午流注开穴法预防生长激素(GH)激发试验不良反应的临床疗效。方法选取2021年11月—2022年10月于广州中医药大学顺德医院进行GH激发试验的矮小症儿童80例,随机分为对照组、观察组,各40例。对照组给予常规护理及治疗,观察组在对照组的基础上加子午流注开穴法贴敷神阙穴。比较两组患儿不良反应情况。结果观察组不良反应发生率为7.5%(3/40),低于对照组的27.5%(11/40),差异有统计学意义(P<0.05);且观察组不良反应出现时间晚于对照组,持续时间短于对照组,差异均有统计学意义(P<0.05)。结论子午流注开穴法贴敷神阙穴,可降低GH激发试验不良反应发生率,减少患儿痛苦,提高家属满意度,保证激发试验顺利进行,值得临床推广。 展开更多
关键词 五迟 矮小症 生长激素激发试验 子午流注开穴法 不良反应 中医外治法
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阿尔茨海默病不同治疗方式研究新进展 被引量:1
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作者 袁行勇 姚春 +6 位作者 陈炜 王晋平 黄钰铧 曲一荻 曾汉林 崔恩山 廖雨芯 《广州医药》 2024年第3期236-244,共9页
阿尔茨海默病(Alzheimer’s disease,AD)是一种复杂的、起病隐秘的、病因不明的、缺乏特异性诊断方式的神经退行性病变。面对与日俱增的患病率,却缺乏有效的治疗方式。中医药治疗方式具有多层次、多靶点、多通路的独特优势,中西医结合... 阿尔茨海默病(Alzheimer’s disease,AD)是一种复杂的、起病隐秘的、病因不明的、缺乏特异性诊断方式的神经退行性病变。面对与日俱增的患病率,却缺乏有效的治疗方式。中医药治疗方式具有多层次、多靶点、多通路的独特优势,中西医结合方式的互补,非药物疗法的辅助,干细胞疗法、新的分子药物、抗体及蛋白疫苗、γ感官刺激等新颖的实验阶段新疗法等方式治疗AD。本文综述近年来的不同治疗方式治疗AD研究新进展,旨在为临床上治疗AD提供新思路、新方法及参考价值。 展开更多
关键词 阿尔茨海默病 治疗方式 中西医疗法 干细胞疗法 新疗法
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蒲地蓝消炎口服液治疗小儿支原体肺炎有效性和安全性的Meta分析 被引量:1
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作者 王雅星 姜甘 +3 位作者 吕健 路振凯 黎元元 谢雁鸣 《世界中医药》 CAS 北大核心 2024年第17期2621-2626,共6页
目的:系统评价中成药蒲地蓝消炎口服液联合西药治疗小儿支原体肺炎(MPP)的临床有效性和安全性。方法:通过全面检索关于蒲地蓝消炎口服液联合西药治疗小儿支原体肺炎的随机对照试验(RCT)文献,利用统计软件RevMan5.3提取并分析数据。结果... 目的:系统评价中成药蒲地蓝消炎口服液联合西药治疗小儿支原体肺炎(MPP)的临床有效性和安全性。方法:通过全面检索关于蒲地蓝消炎口服液联合西药治疗小儿支原体肺炎的随机对照试验(RCT)文献,利用统计软件RevMan5.3提取并分析数据。结果:共纳入13项研究,共包含1313例患者,其中观察组661例,对照组652例。蒲地蓝消炎口服液联合西药治疗小儿支原体肺炎,临床有效率高于单用西药(RR=1.17,95%CI为1.13~1.22,P<0.0001),退热时间(MD=-1.29,95%CI为-1.35~-1.22,P<0.0001),听诊肺部啰音消退时间(MD=-1.77,95%CI为-1.85~-1.69,P<0.0001)及咳嗽症状消退时间(MD=-2.59,95%CI为-2.67~-2.52,P<0.0001)4个方面均优于单用西药。GRADE评价结果显示证据质量以低质量为主。结论:蒲地蓝消炎口服液联合西药优于单独应用西药,且不良反应较少,安全性较好。 展开更多
关键词 小儿支原体肺炎 蒲地蓝消炎口服液 阿奇霉素 随机对照试验 中西医结合疗法 临床疗效 META分析
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中药联合抗肿瘤血管生成药物治疗非小细胞肺癌的研究进展 被引量:1
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作者 刘宝生 周秀丽 +3 位作者 朱彦 刘丽红 于泽胜 王振华 《基层中医药》 2024年第2期112-118,共7页
非小细胞肺癌(NSCLC)是肺癌最为常见的一种病理类型,一半以上的患者确诊时即为进展期肺癌,患者生存期较短。抗肿瘤血管生成药物是目前治疗非小细胞肺癌的重要靶向药物,其临床疗效已获得临床认可,但仍存在耐药性及毒副作用不可耐受的局限... 非小细胞肺癌(NSCLC)是肺癌最为常见的一种病理类型,一半以上的患者确诊时即为进展期肺癌,患者生存期较短。抗肿瘤血管生成药物是目前治疗非小细胞肺癌的重要靶向药物,其临床疗效已获得临床认可,但仍存在耐药性及毒副作用不可耐受的局限性,而中药辨证论治及减毒增效的优点,可减轻药物的不良反应,并提高临床疗效,已成为中西医结合治疗非小细胞肺癌的重要方向。本文主要通过检索2010年1月—2023年6月中国知网、万方、维普及PubMed等数据库中的相关文献,总结近年来不同中药联合各类抗肿瘤血管生成药物治疗NSCLC的相关研究,试从不同角度探讨治疗NSCLC的新思路。 展开更多
关键词 非小细胞肺癌 中药 抗肿瘤血管生成药物 联合治疗
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卵巢早衰激素替代治疗后妊娠1例
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作者 廖才慧 王英 潘丽贞 《中国当代医药》 CAS 2024年第23期155-158,168,共5页
卵巢早衰是卵巢功能减退的终末阶段,指女性在40岁之前的出现闭经、不孕,并伴随卵泡刺激素水平升高(>40 U/L),以及雌激素水平下降等内分泌异常及不同程度的围绝经期症状的出现。卵巢早衰在人群中常发生,卵巢早衰性不孕也成为困扰大部... 卵巢早衰是卵巢功能减退的终末阶段,指女性在40岁之前的出现闭经、不孕,并伴随卵泡刺激素水平升高(>40 U/L),以及雌激素水平下降等内分泌异常及不同程度的围绝经期症状的出现。卵巢早衰在人群中常发生,卵巢早衰性不孕也成为困扰大部分女性的问题。卵巢早衰患者有自然妊娠的机会但概率低,残存的卵泡什么时候发育,什么时候排卵是不可预测的。本文介绍1例卵巢早衰患者进行激素替代治疗后妊娠的病例,该患者在低雌激素临床症状的情况下接受了激素替代和中医治疗,在治疗过程中,该患者因停经40 d自测尿妊娠实验结果呈阳性,且后续彩超检查结果示宫内早孕。通过该病例探讨卵巢早衰与妊娠治疗,以及祖国医学在卵巢早衰中的临床运用,致力于寻找多种治疗方案,以最大限度地改善患者的临床症状,并提高其生活质量。 展开更多
关键词 卵巢早衰 妊娠 激素替代 中医治疗
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中药联合激素治疗卵巢早衰的网状Meta分析
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作者 黄文锐 李怡欣 +2 位作者 黄婷婷 揭慧敏 韩霞 《广州中医药大学学报》 CAS 2024年第4期1063-1074,共12页
【目的】运用网状Meta分析方法筛选中药联合激素治疗卵巢早衰(POF)的最优方案,为POF的临床治疗提供循证依据。【方法】计算机检索知网(CNKI)、维普数据库(VIP)、万方(Wanfang)数据库、中国生物医学文献服务系统(CBM)、PubMed、Cochrane... 【目的】运用网状Meta分析方法筛选中药联合激素治疗卵巢早衰(POF)的最优方案,为POF的临床治疗提供循证依据。【方法】计算机检索知网(CNKI)、维普数据库(VIP)、万方(Wanfang)数据库、中国生物医学文献服务系统(CBM)、PubMed、Cochrane、Embase、Web of Science等国内外主要数据库中有关中药联合激素治疗卵巢早衰的临床随机对照试验(randomized controlled trials,RCTs)。采用Cochrane推荐的质量评价工具与Jadad量表以评估文献质量。采用Rstudio、StataSE 15.1统计软件对数据进行网状Meta分析并绘制图表。【结果】共纳入文献50篇,涉及8种干预措施。纳入研究总体偏倚风险较低,但文献质量总体偏低。网状Meta分析结果显示,在有效率方面,7种中药联合激素干预措施均优于对照组的常规治疗(激素替代疗法),暖宫七味散+常规治疗均优于其余6种中药联合激素干预措施;基于累积排序概率曲线下面积(SUCRA)值,8种干预措施有效率的疗效排序由高到低依次为暖宫七味散+常规治疗(SUCRA=81.2)、滋肾育胎丸+常规治疗(SUCRA=80.0)、左归丸加减+常规治疗(SUCRA=66.1)、安坤种子丸+常规治疗(SUCRA=49.6)、坤泰胶囊+常规治疗(SUCRA=45.2)、二仙汤加减+常规治疗(SUCRA=39.5)、六味地黄丸+常规治疗(SUCRA=37.4)、常规治疗(SUCRA=1.0)。在改善血清卵泡刺激素(FSH)水平方面,左归丸加减+常规治疗优于其余7种干预措施;疗效排序为左归丸加减+常规治疗(SUCRA=97.0)、常规治疗(SUCRA=77.9)、六味地黄丸+常规治疗(SUCRA=76.6)、坤泰胶囊+常规治疗(SUCRA=46.5)、暖宫七味散+常规治疗(SUCRA=38.9)、安坤种子丸+常规治疗(SUCRA=29.9)、二仙汤加减+常规治疗(SUCRA=18.1)、滋肾育胎丸+常规治疗(SUCRA=15.1)。【结论】与常规治疗(激素替代治疗)相比,各种中药联合激素的干预措施在改善卵巢早衰(POF)患者的主要结局指标方面,疗效均较佳。具有最优方案概率最大值的提高有效率的干预措施为暖宫七味散+常规治疗,具有最优方案概率最大值的降低血清FSH水平的干预措施为左归丸加减+常规治疗。但由于纳入研究的质量较低,未来需要开展更多设计严谨的大样本、高质量的随机对照试验,以提供确凿的循证依据。 展开更多
关键词 卵巢早衰 中药疗法 激素替代疗法 有效率 卵泡刺激素(FSH) 系统评价 网状Meta分析
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5-氨基水杨酸口服制剂及联合中药在炎症性肠病治疗中的应用
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作者 程燕 颜冬梅 +1 位作者 李飞 朱卫丰 《中国现代中药》 CAS 2024年第8期1420-1431,共12页
5-氨基水杨酸(5-ASA)是1种从中药柳树皮中分离提纯得到的天然抗炎活性成分水杨酸的衍生物,别名阿米诺水杨酸、美沙拉嗪,是临床治疗炎症性肠病(IBD)并预防其复发的一线药物。尽管目前莎尔福(Salofalk)、亚沙可(Asacol)和潘他沙(Pentasa)... 5-氨基水杨酸(5-ASA)是1种从中药柳树皮中分离提纯得到的天然抗炎活性成分水杨酸的衍生物,别名阿米诺水杨酸、美沙拉嗪,是临床治疗炎症性肠病(IBD)并预防其复发的一线药物。尽管目前莎尔福(Salofalk)、亚沙可(Asacol)和潘他沙(Pentasa)等5-ASA口服结肠靶向制剂已广泛用于IBD的临床治疗,但仍存在在小肠提前释药和受胃肠道生理状态影响显著等制剂缺陷、对克罗恩病和重度溃疡性结肠炎(UC)治疗效果不佳等临床未满足的需求,以及减少UC患者黏膜菌群多样性、长期使用增加用药风险和降低患者服药依从性等问题。开发硅胶纳米粒、水凝胶等新型递药载体,基于pH依赖、时滞控制和菌群/酶触发等多机制结合释药原理设计新型口服结肠靶向制剂从而解决制剂缺陷问题,提高5-ASA疗效和患者服药耐受性、依从性是目前制剂研究的重点。此外,5-ASA口服制剂联合中药保留灌肠、中药口服制剂和注射液等治疗IBD可发挥协同抗炎作用,实现增效减毒目的。对5-ASA口服制剂品种、近年来新型制剂和递药载体的研究进展,以及与中药联用的临床应用和研究现状等进行综述,为5-ASA口服制剂的剂型改造、载体材料研究和临床用药等提供参考。 展开更多
关键词 5-氨基水杨酸 口服结肠靶向制剂 递药载体 联合中药 炎症性肠病
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中药面膜联合低能量调Q激光治疗面部炎症后色素沉着 被引量:1
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作者 蒋姝枫 蔡宏 《中国美容医学》 CAS 2024年第2期111-114,共4页
面部炎症后色素沉着(Post-inflammatory hyperpigmentation,PIH)是一种常见的获得性色素沉着疾病,通常由各种皮肤急慢性炎症或损伤导致,属中医“黧黑斑”范畴。面部炎症后色素沉着严重影响患者身心健康,目前单一治疗方法疗效欠佳,存在... 面部炎症后色素沉着(Post-inflammatory hyperpigmentation,PIH)是一种常见的获得性色素沉着疾病,通常由各种皮肤急慢性炎症或损伤导致,属中医“黧黑斑”范畴。面部炎症后色素沉着严重影响患者身心健康,目前单一治疗方法疗效欠佳,存在一定弊端。本文报道采用中药面膜联合低能量调Q激光治疗面部炎症后色素沉着2例,效果良好,为临床提供治疗了新思路。 展开更多
关键词 面部炎症后色素沉着 黧黑斑 中药面膜 调Q激光 联合治疗
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运动疗法配合中医辨证饮食调护对胃炎患者脾胃功能恢复的影响
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作者 庄婉玲 庄晓强 许绵绵 《中国现代药物应用》 2024年第16期23-27,共5页
目的观察运动疗法配合中医辨证饮食调护对胃炎患者脾胃功能恢复的影响。方法80例胃炎患者,依据随机数字表法分为对照组及观察组,各40例。对照组行常规干预,观察组行运动疗法配合中医辨证饮食调护。比较两组干预前后的胃肠动力学指标[胃... 目的观察运动疗法配合中医辨证饮食调护对胃炎患者脾胃功能恢复的影响。方法80例胃炎患者,依据随机数字表法分为对照组及观察组,各40例。对照组行常规干预,观察组行运动疗法配合中医辨证饮食调护。比较两组干预前后的胃肠动力学指标[胃窦收缩幅度(ACA)、胃窦收缩频率(ACF)、胃窦运动指数(MI)]水平、血清胃肠激素[血清胃泌素(GAS)、生长抑素(SS)、胃动素(MTL)]水平、中医证候积分、Barthel指数、生活质量及满意度。结果两组干预后ACA、ACF、MI与干预前比较均提高,且观察组干预后ACA(53.13±5.28)mm Hg/2 h(1 mm Hg=0.133 kPa)、ACF(72.45±6.76)次/h、MI(14.58±2.12)均高于对照组的(47.51±4.25)mm Hg/2 h、(65.32±6.65)次/h、(12.41±2.05),差异具有统计学意义(P<0.05)。两组干预后GAS、SS水平与干预前比较均降低,MTL水平与干预前比较升高,且干预后观察组GAS(62.42±5.32)ng/L、SS(20.42±2.53)pg/ml均低于对照组的(68.31±6.14)ng/L、(25.63±2.78)pg/ml,MTL(76.83±7.33)pg/ml高于对照组的(70.37±6.80)pg/ml,差异具有统计学意义(P<0.05)。两组干预后中医证候积分与干预前比较降低,Barthel指数与干预前比较升高,且干预后观察组中医证候积分(2.01±0.76)分低于对照组的(3.63±0.67)分,Barthel指数(80.38±5.43)分高于对照组的(68.37±5.72)分,差异具有统计学意义(P<0.05)。两组干预后生理、心理、社会、环境、独立、精神世界/宗教/个人信仰评分与干预前比较均提高,且组间对比观察组干预后均高于对照组,差异具有统计学意义(P<0.05)。观察组满意度95.00%高于对照组的80.00%,差异具有统计学意义(P<0.05)。结论运动疗法配合中医辨证饮食调护对胃炎患者脾胃功能恢复及日常生活能力、生活质量的提升有促进作用,值得临床推广。 展开更多
关键词 胃炎 运动疗法 中医辨证饮食调护 脾胃功能 胃肠激素水平 BARTHEL指数 满意度
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