Analysis of the Effect of Transcutaneous Electrical Stimulation of Acupoints Combined with Rehabilitation Training in The Treatment of Upper Limb Dysfunction After Stroke

Objective:To analyze the effect of combining transcutaneous electrical acupoint stimulation(TEAS)with rehabilitation training in patients with upper limb dysfunction after stroke(ULDAS).Methods:A total of 130 ULDAS patients who were hospitalized and rehabilitated in Wuxi Xinwu District Rehabilitation Hospital from May 2021 to May 2023 were selected and randomly divided into Group A(65 cases,rehabilitation training)and Group B(65 cases,rehabilitation training+TEAS).The effects of the two groups were compared.Results:After treatment,the upper limb functional indexes of Group B were better than those of Group A(P<0.05).The rate of muscle tone grades 0-4 in Group B was higher than those of Group A(P<0.05).Conclusion:The function of upper limbs and muscle strength of ULDAS patients improved by combining TEAS with rehabilitation training.

Effect of transcutaneous electrical acupoint stimulation combined with palonosetron on chemotherapy-induced nausea and vomiting: a single.blind,randomized, controlled trial

Background: Chemotherapy?induced nausea and vomiting adversely affects the quality of life of patients who receive chemotherapy via intravenous infusion or transcatheter arterial chemoembolization(TACE). This study aimed to investigate the clinical effects of transcutaneous electrical acupoint stimulation(TEAS) on nausea and vomiting after TACE.Methods: A total of 142 patients who received TACE with cisplatin for primary or metastatic liver cancer were assigned to the active?acupuncture(n = 72) or placebo?acupuncture(n Hegu(LI4), Neiguan(P6), an= 70) groups using a covariate?adaptive randomization at a ratio of 1:1. The acupointsd Zusanli(ST36) were stimulated twice daily for 6 days. The effects of TEAS on nausea and vomiting were assessed by using occurrence rate and severity of these symptoms. Anorexia scale and M. D. Anderson Symptom Inventory(MDASI) scores were secondary endpoints and were used to assess the effect of TEAS on patient appetite and quality of life. The safety of the treatments was also monitored.Results: Between the two groups, the differences in occurrence rates and severities of nausea and vomiting after TACE were not significant(all P > 0.05). From the second day after TACE, anorexia scores were significantly lower in the active?acupuncture group than in the placebo?acupuncture group and continued to decrease over time with treat?ment(all P values less than 0.01). On days 0, 1, and 2, the mean MDASI scores for the active?acupuncture group were slightly lower than those for the placebo?acupuncture group, but the differences were not statistically significant(all P > 0.05). No significant differences were found between the two groups in the occurrence rate of any adverse event(P > 0.05).Conclusion: TEAS appears to be a safe and effective therapy to relieve patients' gastrointestinal discomfort after chemotherapy.

Evaluation of the Efficacy of Transcutaneous Electrical Acupoint Stimulation during the Treatment of Painless Colonoscopy

Objective:To investigate the clinical efficacy of transcutaneous electrical acupoint stimulation combined with propofol infusion during the treatment of patients under colonoscopy.Methods:A total of 90 patients received painless colonoscopy were randomly divided into three groups:transcutaneous electrical acupoint stimulation combined with propofol group(group T),sufentanil combined with propofol group(group S)and propofol group(group P),with 30 cases in each group.The patients in group T were anesthetized with propofol after transcutaneous electrical acupoint stimulation of 30min at Hegu(LI4),Neiguan(PC6),Zusanli(ST36),Shangjuxu(ST37)and Sanyinjiao(SP6)on both sides,and the electrical stimulation lasted until the end of the operation.Group S and group P were pasted electrode slices at the same acupoint with group T,but no electrical stimulation was given.The other treatments were the same as those in group T.Group S was given sufentanil 0.1ug/kg at the beginning of anesthesia.The levels of blood pressure(MAP),heart rate(HR)and pulse oxygen saturation(SpO2)were continuously monitored at time points of entering operating room(T0),disappearance of eyelash reflex(T1),during operation(through the liver region T2)and immediately after operation(T3),and the total dosage of propofol,awakening time and incidence of adverse reactions in each group were recorded.Results:Compared with group P,the blood pressure and heart rate of the patients at T1 and T2 in group T were more stable(P<0.05),the awakening time after operation was significantly shorter(P<0.05),and the dosage of propofol was significantly lower than that in group P(P<0.05).The incidence of bradycardia,hypotension and respiratory depression decreased significantly(P<0.05).Compared with group S,the postoperative awakening time of group T was significantly shorter(P<0.05),and there was no significant difference in other indexes.Conclusion:Transcutaneous electrical acupoint stimulation is effective during the treatment of analgesia under colonoscopy.It can reduce the dosage of anesthetics,reduce the incidence of postoperative adverse reactions and shorten the awakening time of patients.

Research on the Different Frequencies of Transcutaneous Electrical Acupoint Stimulation for Postpartum Pelvic Girdle Pain

Objective:To observe the clinical effect of different frequencies of transcutaneous electrical acupoint stimulation in treating postpartum pelvic girdle pain and promoting postpartum rehabilitation.Methods:From January to September 2022,300 patients with pelvic girdle pain after spontaneous delivery in a hospital in Shaanxi Province were selected and randomly divided into three groups,low frequency,high frequency,and alternating frequency,with 100 cases in each group.In addition to routine postpartum care and psychological counseling,the three groups received transcutaneous electrical acupoint stimulation at low-frequency(2 Hz,)high-frequency(100 Hz),and alternating frequency(2/100 Hz),respectively.The differences in initial pain,pain scores before and after treatment,satisfaction with analgesic effect,and postpartum rehabilitation effect were evaluated among the three groups of patients.Results:There was a significant correlation between maternal age and postpartum pelvic girdle pain(P<0.001),but no correlation was observed between newborn birth weight and postpartum pelvic girdle pain(P>0.05).After 1d/2d of treatment,the pain scores and rehabilitation effect of patients in the alternating-frequency group and low-frequency group were significantly better than those in the high-frequency group,and the postpartum curative effect of patients in the alternating-frequency group was the best,followed by the low-frequency group,and the high-frequency group;the differences were statistically significant(P<0.001).Among the three groups,the alternating-frequency group had the highest satisfaction with the analgesic effect and the highest rate of selecting the same analgesic regimen the next time;the differences were statistically significant(P<0.001).Conclusion:Transcutaneous electrical acupoint stimulation at different frequencies is safe and effective in treating postpartum pelvic girdle pain and beneficial to postpartum rehabilitation.Sparse-dense wave stimulation is effective in treating postpartum pelvic girdle pain.It has the best effect in promoting postpartum rehabilitation and the highest patient satisfaction.Therefore,its application in clinical practice is highly recommended.

Transcutaneous electrical acupoint stimulation in adult patients receiving gastrectomy/colorectal resection:A randomized controlled trial

BACKGROUND Acupuncture promotes the recovery of gastrointestinal function and provides analgesia after major abdominal surgery.The effects of transcutaneous electrical acupoint stimulation(TEAS)remain unclear.AIM To explore the potential effects of TEAS on the recovery of gastrointestinal function after gastrectomy and colorectal resection.METHODS Patients scheduled for gastrectomy or colorectal resection were randomized at a 2:3:3:2 ratio to receive:(1)TEAS at maximum tolerable current for 30 min immediately prior to anesthesia induction and for the entire duration of surgery,plus two 30-min daily sessions for 3 consecutive days after surgery(perioperative TEAS group);(2)Preoperative and intraoperative TEAS only;(3)Preoperative and postoperative TEAS only;or(4)Sham stimulation.The primary outcome was the time from the end of surgery to the first bowel sound.RESULTS In total,441 patients were randomized;405 patients(58.4±10.2 years of age;247 males)received the planned surgery.The time to the first bowel sounds did not differ among the four groups(P=0.90;log-rank test).On postoperative day 1,the rest pain scores differed significantly among the four groups(P=0.04;Kruskal–Wallis test).Post hoc comparison using the Bonferroni test showed lower pain scores in the perioperative TEAS group(1.4±1.2)than in the sham sti-mulation group(1.7±1.1;P=0.04).Surgical complications did not differ among the four groups.CONCLUSION TEAS provided analgesic effects in adult patients undergoing major abdominal surgery,and it can be added to clinical practice as a means of accelerating postoperative rehabilitation of these patients.

Transcutaneous acupoint electrical stimulation(TAES)for pre-operative anxiety:a prospective observational pilot investigation

Objective:Transcutaneous acupoint electrical stimulation(TAES)treatment is effective for post-operative anxiety.The investigation was designed to study the feasibility and effectiveness of TAES treatment for pre-operative anxiety.Methods:62 volunteered surgical patients were included in the pilot investigation.They all received TAES treatment for 30 minutes in the evening of the day before operation.Hegu(LI4)and Neiguan(PC6)of both sides were selected as the treatment acupoints.The anxiety degrees were measured by State-Trait Anxiety Inventory.Heart rate and blood pressure were also recorded.Results:After TAES,pre-operative anxiety measured by State-Trait Anxiety Inventory dropped by almost 12%,and both heart rate and systolic blood pressure decreased significantly.Conclusion:The pilot investigation of TAES for pre-operative anxiety can successfully test the feasibility of outcome measurements and provide necessary data for calculating the sample size of a subsequent randomized controlled trial.

Effect of percutaneous electrical stimulation at the Baliao point on preventing postpartum urinary retention after labor analgesia

BACKGROUND Anesthetic drugs used in labor analgesia also paralyze the bladder muscle by blocking the sacral plexus,thereby affecting maternal postpartum spontaneous urination and increasing the risk of postpartum urinary retention(PUR).AIM To analyze the effect of percutaneous electrical stimulation at the Baliao point combined with biofeedback therapy for PUR prevention.METHODS We selected 182 pregnant women who received labor analgesia in obstetrics between June 2022 and December 2023.They were divided into the combined therapy group(transcutaneous electrical stimulation of the Baliao point combined with biofeedback therapy)and the control group(biofeedback therapy alone).The first spontaneous urination time,first postpartum urine volume,bladder residual urine volume,postpartum hemorrhage volume,pre-urination waiting time,PUR incidence,adverse reactions,and the intervention’s clinical efficacy were compared between the two groups.RESULTS The first spontaneous urination time after delivery was more delayed(2.92±1.04 h vs 3.61±1.13 h,P<0.001),with fewer initial postpartum urine(163.54±24.67 mL vs 143.72±23.95 mL,P<0.001),more residual bladder urine(54.81±10.78 mL vs 65.25±13.52 mL,P<0.001),more postpartum bleeding(323.15±46.95 mL vs 348.12±45.03 mL,P=0.001),and longer waiting time for urination(0.94±0.31 min vs 1.29±0.42 min,P<0.001),in the control group than in the combined therapy group.The control group also had higher PUR incidence(4.65%vs 15.85%,P=0.016).Both groups had no adverse reactions,but the clinical total efficacy rate of the intervention was significantly higher in the combined therapy group than in the control group(95.35%vs 84.15%,P=0.016).CONCLUSION Percutaneous electrical stimulation of the Baliao point combined with biofeedback can significantly promote postpartum micturition of parturients with labor analgesia,thereby effectively preventing PUR occurrence.

基于光学相干断层扫描血管成像术探讨Eye-TEAS防治儿童近视疗效及作用机制

目的:基于光学相干断层扫描血管成像术(OCTA)探讨眼周经皮穴位电刺激仪(Eye-TEAS)防治儿童近视的疗效和机制。方法:纳入60名近视儿童,记录黄斑中心凹下脉络膜厚度(SFCT)等眼部各参数水平,并对各参数进行相关性分析;采用Eye-TEAS对受试者进行3个月的干预治疗,每天30 min,每周使用不低于5次。检测Eye-TEAS干预前、干预1次后、干预1个月后、干预3个月后受试者等效屈光度(SER)、眼轴长度(AL)、SFCT及黄斑区3 mm×3 mm面积内的脉络膜中大血管密度(CVD)、脉络膜毛细血管密度(CCVD)的变化情况。结果:58名近视儿童完成了干预及随访,在基线数据观察中,SER与SFCT、CCVD均呈显著正相关(P<0.01),AL与SER、SFCT、CVD、CCVD呈显著负相关(P<0.05或P<0.01)。相较于干预前,干预第1次后、1个月后、3个月后SER、AL均未发生显著变化(P>0.05)。干预第1次后SFCT与基线水平比较,差异无统计学意义(P>0.05)。干预1个月、3个月后SFCT与基线水平比较,差异均有统计学意义(P<0.05),其中干预1个月后SER变化和SFCT变化呈显著正相关(P<0.05)。在干预第1次、干预1个月后CVD较基线水平增加(P<0.05),但干预3个月后CVD与基线水平比较,差异无统计学意义(P>0.05)。相较于基线数据,干预1个月后和干预3个月后CCVD均显著升高(P<0.01)。结论:近视儿童SFCT、眼底微循环情况与AL、SER具有高度相关性;Eye-TEAS干预后SFCT显著增厚,CVD、CCVD也显著增加,这可能与Eye-TEAS通过影响脉络膜血流的变化减缓近视的进展有关。

五音配合TEAS疗法在乳腺肿瘤患者围术期焦虑紧张情绪方面的应用与研究

目的 探讨经皮穴位电刺激(TEAS)联合五音疗法对乳腺良性肿瘤患者围术期焦虑的影响。方法 选取2023年1月至2023年7月河南中医药大学第一附属医院收治的160例乳腺良性肿瘤患者,以随机数字表法分成研究组(n=80,TEAS联合五音疗法)与对照组(n=80,TEAS),比较两组焦虑情况、术后恢复程度、疼痛程度、麻醉药物用量、不良反应。结果 术后1个月(T_(5))两组汉密尔顿焦虑量表(HAMA)评分均降低,且研究组低于对照组,差异有统计学意义(P<0.05);术后3 d(T_(4))两组术后恢复质量评估量表(PQRS)评分均低于术前30 min(T_(1)),差异有统计学意义(P<0.05),研究组T_5时PQRS评分高于T_(1),差异有统计学意义(P<0.05),研究组T_(4)、T_(5)时PQRS评分高于对照组,差异有统计学意义(P<0.05);研究组术后6 h(T_2)、术后第1 d(T_(3))、T_(4)时痛觉模拟评分(VAS)均低于对照组,差异有统计学意义(P<0.05);研究组丙泊酚、瑞芬太尼用量少于对照组,差异有统计学意义(P<0.05);研究组不良反应发生率(6.25%)低于对照组(18.75%),差异有统计学意义(P<0.05)。结论 TEAS联合五音疗法应用于乳腺良性肿瘤患者围术期中,能够减轻患者焦虑情绪,促进术后恢复,缓解术后疼痛,减少术中麻醉药物用量,减少不良反应。

Transcutaneous electrical acupoint stimulation benefits postoperative pain relief of oocyte retrieval:A randomized controlled trial

Background Transvaginal oocyte retrieval is frequently followed by adverse events related to anesthesia and the procedure.Some research showed that transcutaneous electrical acupoint stimulation(TEAS)can relieve intraoperative pain and postoperative nausea.Objective This study examined whether TEAS can alleviate pain and relieve adverse symptoms after oocyte retrieval.Design,setting,participants and interventions Altogether 128 patients were randomly divided into the TEAS group and the mock TEAS group.The two groups received a 30-minute-long TEAS or mock TEAS treatment that began 30 min after oocyte retrieval.Main outcome measures The primary outcome was the visual analog scale(VAS)pain score.Secondary outcomes were pressure pain threshold,McGill score,pain rating index(PRI),present pain intensity(PPI),VAS stress score,VAS anxiety score,and postoperative adverse symptoms.Results The baseline characteristics of the two groups were comparable(P>0.05).The VAS pain scores of the TEAS group were lower than those of the mock TEAS group at 60 and 90 min after oocyte retrieval(P<0.05).The McGill score,PRI and PPI in the TEAS group were significantly lower than those in the control group at 60 min after oocyte retrieval(P<0.05).However,the two groups had equivalent beneficial effects regarding the negative emotions,such as nervousness and anxiety(P>0.05).The TEAS group was superior to the mock TEAS group for relieving postoperative adverse symptoms(P<0.05).Conclusion TEAS treatment can relieve postoperative pain and postoperative adverse symptoms for patients undergoing oocyte retrieval.

TEAS联合核心训练干预产后腹直肌分离及腰背痛的可行性

目的观察TEAS联合核心训练干预产后腹直肌分离与腰背痛的的可行性。方法选择2020年1月—2022年12月浙江中医药大学附属湖州中医院90例产后腰痛患者作为研究对象,对腹直肌分离程度与腰背疼痛评分进行Pearson相关性分析。将90例产后腰痛患者随机分成三组,分别为对照组、治疗1组、治疗2组,每组30例。对照组采用常规的产后自然恢复法;治疗1组在对照组的基础上加予核心训练,1次/d,5次/周,4周为1个疗程,连续1个疗程;治疗2组在治疗1组的基础上采用TEAS疗法,1次/d,5次/周,4周为1个疗程,连续1个疗程。治疗前及1个疗程结束后,评估腹直肌分离程度(IRD)、腰背疼痛症状(SF-MPQ)、身体质量指数(BMI),并观察治疗前后这些指标的变化。结果治疗结束后,各组IRD、SF-MPQ评分及BMI较治疗前明显下降,下降幅度以治疗2组最为明显,差异有统计学意义(P<0.05)。IRD与SF-MPQ评分之间呈正相关(r=0.320,P<0.05)。结论腹直肌分离与腰背痛具有相关性,TEAS联合核心训练干预可有效缩小产后腹直肌分离程度,减轻腰背疼痛,降低身体质量指数,该疗法具有临床可行性。

Review of transcutaneous electrical acupoint stimulation and related devices

A review was undertaken of the operation process and development of transcutaneous electrical acupoint stimulation(TEAS)and related devices for TEAS,with the aim to offer a reference for developing an international standard for the basic safety and essential performance of the devices.The articles related to TEAS and instruction of devices for TEAS were searched using the EMBASE,MEDLINE,and Web of Science databases with the time period from inception to July 18,2023.In the absence of a parameter description of the stimulators,a multimeter was used to measure the output voltage,resistance,and current.Thirty-two related devices for TEAS were obtained.The safety parameters ofmost devices were neither clearly defined,nor standardized,and in some cases weremissing.There was a noticeable disparity in the upper safety limits of the output current among the devices.The sizes of the skin electrode pads as well as the lengths of the electrode connecting wires of most devices were not clearly indicated.Acupoints on different parts of the human body,including the upper limbs,head,auricle,chest,abdomen,trunk,and lower limbs,required different maximum tolerable current intensities and current densities.It is important to indicate comprehensive output/safety parameters and essential performance for devices for TEAS to meet the need of global distribution,achieve precise stimulation parameters at different acupoints across the human body,and allay any safety concern of national therapeutic device authorities,the regulators,manufacturers,and end users.

Efficacy of transcutaneous electrical acupoint stimulation(TEAS)for menopausal insomnia and its effect on serum hormone levels

Objective:To explore the therapeutic efficacy and mechanism of transcutaneous electrical acupoint stimulation(TEAS)for menopausal insomnia.Methods:A total of 80 patients with menopausal insomnia were randomly divided into a control group and an observation group,with 40 cases in each group.The patients in the control group received conventional Western medication treatment,and the patients in the observation group received TEAS on the basis of conventional Western medication treatment.The treatment for both groups lasted for 4 weeks.Before and after treatment,Pittsburgh sleep quality index(PSQI)and modified Kupperman scale were evaluated,and the serum levels of estradiol(E2)and follicular stimulating hormone(FSH)were measured.The therapeutic efficacy was evaluated after treatment.Results:After treatment,the total effective rate of the observation group was significantly higher than that of the control group(P<0.05);in the control group,the improvement of PSQI score was significant(P<0.05),while the change of modified Kupperman score was insignificant(P>0.05);the PSQI and Kupperman scores in the observation group were significantly improved after treatment(both P<0.05),and there were significant differences between the observation group and the control group in PSQI and Kupperman scores(both P<0.05).After treatment,the serum E2 and FSH levels in the control group were not statistically different from those before treatment(both P>0.05);the serum E2 level was significantly increased(P<0.05),and the FSH level was decreased(P<0.05)in the observation group after treatment,and the between-group differences in serum levels of E2 and FSH were significant(both P<0.05).Conclusion:TEAS plus conventional Western medication in treating menopausal insomnia is effective,and can significantly improve the symptoms of insomnia and menopause,which may be related to the regulation of serum E2 and FSH levels.

TEAS复合药物全麻行控制性降压至60%基础MAP水平时的肝保护效应分析

目的:探讨经皮穴位电刺激(Transcutaneous Electrical Acupoint Stimulation,TEAS)复合药物全麻行控制性降压对肝脏的影响,并为临床行针药复合麻醉提供实验依据。方法:18只雄性比格犬随机分为单纯药物全麻组(单纯全麻组)(6只)、单纯药物全麻行控制性降压组(对照组)(6只)和经皮穴位电刺激复合药物全麻行控制性降压组(实验组)(6只)。后两组动物均以异氟醚联合硝普钠行控制性降压,将动脉血压降至60%基础平均动脉血压(Mean arterial pressure,MAP)水平并维持60min,单纯全麻组不行控制性降压。实验组采用TEAS干预处理,刺激强度(4±1)mA,频率2/100Hz,穴位选用犬双侧"合谷(LI 4)"、"曲池(LI 11)"、"足三里(ST 36)"、"三阴交(SP 6)",电刺激在动物生理状态稳定后开始至维持目标MAP60min后停止。采用激光多普勒组织血流仪监测相应时间点肝组织表面血流的变化,用免疫组化法检测术后肝组织中GSH活性、T-SOD活力以及MDA含量的变化,并采用TUNEL法检测术后72h肝组织细胞凋亡数。结果:在行控制性降压至目标低血压(T3)时,对照组肝血流显著低于基础水平(P<0.05),而实验组肝血流未明显降低,在目标低血压维持10min(T4)时,两控压组肝血流显著低于各自基础水平(P<0.05),在维持20min至维持60min阶段(T5～T7),两控压组肝血流显著低于单纯全麻组水平和各自基础水平(P<0.05),且对照组肝血流维持水平更低,在血压回升阶段,实验组肝血流上升明显,在血压回升10min(T8)时,实验组肝血流已基本恢复,而对照组肝血流仍低于同期单纯全麻组水平,在血压回升60min和回升结束(T11～T12),实验组肝血流明显高于对照组水平(P<0.05)。与单纯全麻组相比,控制性降压术后两控压组GSH活性均有显著升高(P<0.05),且实验组较对照组相比升高趋势更明显。实验组SOD/MDA比值显著升高(P<0.05),而对照组升高不明显。实验组肝组织细胞凋亡数(3.2±1.09)明显低于同水平对照组(5.47±1.02)(P<0.05),但与空白组(3.49±1.42)相比,无统计学差异(P>0.05)。结论:TEAS复合药物全麻行控制性降压能有效改善肝组织血流的低灌注状态,增强肝脏的抗自由基能力,抑制肝细胞凋亡,起到肝保护作用。

TEAS对IVF肾气虚型患者子宫内膜容受性影响

目的:观察经皮穴位电刺激(TEAS)治疗对IVF肾气虚型患者冻胚移植周期子宫内膜容受性的影响。方法:将我院收集的153例符合纳入标准的行冻胚移植的肾气虚型患者随机分为TEAS治疗组、MOCK组、对照组。观察3组患者治疗前后临床指标的变化,以及妊娠结局的差异。结果:3组患者的平均年龄、不育年限、体重指数、基础FSH比较差异无统计学意义。治疗后,TEAS组患者中医证候评分较治疗前明显降低,差异有统计学意义(P<0.05)。黄体酮注射日TEAS组的子宫内膜厚度高于MOCK组和对照组,差异有统计学意义(P<0.05);TEAS组A型与AB型子宫内膜百分比、(+、++)型子宫内膜下血流明显高于MOCK组和对照组,差异有统计学意义(P<0.05);黄体酮注射日3组血清E2、P比较,差异无统计学意义(P>0.05);TEAS组PI、RI、S/D低于治疗前,与MOCK组、对照组比较明显降低,差异均有统计学意义(P<0.05),治疗前后MOCK组与对照组两组间、组内比较差异均无统计学差异(P>0.05)。TEAS组HCG阳性率及临床妊娠率明显高于MOCK组与对照组,差异有统计学意义(P<0.05)。MOCK组与对照组比较无统计学差异(P>0.05)。结论:TEAS治疗能改善IVF肾气虚型患者的中医临床症状及体征,增加子宫内膜厚度,降低子宫内膜血流参数PI、RI、S/D,进而提高患者的子宫内膜容受性,改善临床妊娠结局。

中医证候量表评价TEAS治疗腹泻型肠易激综合征的相关性研究

目的:应用中医证候量表评价经皮穴位电刺激法(TEAS)治疗腹泻型肠易激综合征(IBS-D)的相关性。方法:110例IBS-D患者随机分为两组,治疗组予TEAS刺激太冲、阴陵泉和天枢三穴,每天2次;对照组予TEAS模拟治疗,疗程4周。评价中医证候量表积分与肠道症状积分、生活质量积分的相关性,并评估治疗前后受试者的中医证候改善情况。结果:肠道症状总积分以及腹痛程度、腹痛天数、腹胀情况、排便满意度、生活干扰度、排便次数、急迫天数等与中医证候呈正相关(P<0.05,P<0.01);生活质量总积分以及睡眠质量、精力改变、工作影响等与中医证候积分呈负相关(P<0.05,P<0.01)。治疗结束后,TEAS治疗组对主症大便泄泻、腹痛、胸胁胀闷,次症脘腹胀满、抑郁烦躁、肠鸣矢气、嗳气、太息,以及中医证候总积分的改善优于TEAS模拟组(P<0.05,P<0.01)。结论:中医证候与IBS-D患者的肠道症状、生活质量相关,采用中医证候量表能反映IBS-D肝气乘脾证的证候改善情况,TEAS能有效改善IBS-D肝气乘脾证患者的中医证候。

TEAS复合药物全麻行控制性降压后胃血流的变化

目的:探讨经皮穴位电刺激(transcutaneous electrical acupoint stimulation,TEAS)复合药物全麻行控制性降压至不同血压水平的胃血流变化,从而明确针药复合麻醉的胃保护机制.方法:54只,♂,比格犬随机分为9组:单纯全麻组、60%对照组、60%实验组、50%对照组、50%实验组、40%对照组、40%实验组、30%对照组、30%实验组,每组6只,后8组动物均以异氟醚联合硝普钠行控制性降压,将动脉血压降至60%、50%、40%、30%基础平均动脉血压水平并维持60min,单纯全麻组不行控制性降压.实验组采用TEAS干预处理,采用激光多普勒组织血流仪监测不同水平相应时间点胃表面血流的变化.结果:在行控制性降压至目标低血压水平(T0)时,所有对照组胃血流均显著低于各自基础水平(P<0.05),而60%实验组、50%实验组胃血流未明显降低,在维持10min(T1)时,除50%实验组外,其他各控压组胃血流均显著低于各自基础水平和同期单纯全麻组水平(P<0.05),50%实验组与同水平对照组相比有显著统计学差异(P<0.05),在血压回升阶段,50%、30%、40%实验组胃血流先后恢复至基础水平和同期单纯全麻组水平,而同水平对照组未明显恢复.结论:轻度控压时(尤其是50%水平),TEAS的胃保护效应明显.重度控压时(尤其是30%水平),TEAS基本无保护效应,但在血压回升结束时,TEAS可促进胃血流的较快恢复.

基于脑电非线性动力学特征探究TEAS内关穴对焦虑的影响

基于脑电非线性动力学特征,探究经皮穴位电刺激(TEAS)内关穴对焦虑的影响及其机制。实验选取12位焦虑受试者随机分为TEAS内关穴干预组(穴位组)和TEAS非穴位干预组(非穴位组),分别采集电刺激前后各组受试者脑电数据,提取脑电信号的特征近似熵(ApEn)与关联维数(D_(2)),分析大脑复杂度的变化,同时比较电刺激前后焦虑自评量表(SAS)评分变化进行效果评定。实验表明,电刺激后穴位组的SAS量表评分比刺激前显著降低,且各个脑区的复杂度均存在下降趋势,脑电信号的ApEn在AF3、F7、F3、P7、F8、F4、AF4通道具有显著性差异(p<0.05),D_(2)在AF3、F3、Fc5、T7、P7、F8、F4、AF4通道存在显著性差异(p<0.05);但非穴位组量表评分及参数值均无明显变化。进而得出TEAS内关穴能有效缓解焦虑情绪,并改善各脑区的复杂度,尤以左、右额区及左右颞区最为明显。

经皮穴位电刺激配合音乐疗法(TEASMT)治疗肠易激综合征疗效观察

目的:观察经皮穴位电刺激配合音乐疗法治疗肠易激综合征的疗效。方法:将250例患者随机分为观察组和对照组,每组125例。观察组给予经皮穴位电刺激配合音乐疗法和口服安慰剂治疗;对照组给予口服654-2片,思连康片,复方谷氨酰胺肠溶胶囊的药物治疗和经皮穴位电刺激安慰治疗。3个疗程后,观察两组的各症状评分。结果:治疗后两组各症状积分均低于治疗前,其中观察组腹痛、腹胀、排便不尽感、黏液便积分显著低于对照组(P<0.05,P<0.01)。结论:经皮穴位电刺激配合音乐疗法对肠易激综合征患者疗效显著。

TEAS在肝脏缺血/再灌注过程中对肝功能及肝细胞形态学变化的影响

目的:探讨经皮穴位电刺激(TEAS)在肝脏缺血/再灌注(I/R)过程中对肝功能生化指标、肝细胞形态学的影响。方法:将12只雄性SD大鼠随机分为对照组、模型组、模型+假TEAS组、模型+TEAS组,每组3只。对照组仅行开腹不使用血管夹闭处理,模型组建立非致死性肝脏节段(70%)I/R模型,模型+假TEAS组使用安慰贴片取穴向外旁开5 mm,不实施任何电流刺激,模型+TEAS组以TEAS干预,实验过程中TEAS介入共3次。采用全自动生化分析仪及免疫组化技术测定各组大鼠血清谷丙转氨酶(ALT)、谷草转氨酶(AST)、肝组织乙酰转移酶(CAT)和谷胱甘肽(GSH)等肝功能指标的变化,并对肝组织行苏木精-伊红(HE)染色,观察各组切片炎症细胞浸润情况。结果:模型组、模型+假TEAS组、模型+TEAS组大鼠的ALT、AST含量均高于对照组,差异具有统计学意义(P<0.05);与模型组相比,模型+TEAS组大鼠的ALT、AST含量均明显降低,差异具有统计学意义(P<0.05)。模型组、模型+假TEAS组、模型+TEAS组大鼠的GSH、CAT含量均低于对照组,差异具有统计学意义(P<0.05);与模型组相比,模型+TEAS组大鼠的GSH、CAT含量均有不同程度的增高,但是各组间比较,差异无统计学意义(P>0.05)。HE染色显示模型+TEAS组的炎症细胞浸润情况明显好于模型组。结论:TEAS在肝脏I/R过程中能有效改善肝功能损伤情况,并能有效改善在肝脏I/R后肝细胞的形态学变化,起到肝保护作用。