Outlet Temperature Correlation and Prediction of Transfer Line Exchanger in an Industrial Steam Ethylene Cracking Process

Predicting the best shutdown time of a steam ethylene cracking furnace in industrial practice remains a challenge due to the complex coking process. As well known, the shutdown time of a furnace is mainly determined by coking condition of the transfer line exchangers （TLE） when naphtha or other heavy hydrocarbon feedstocks are cracked. In practice, it is difficult to measure the coke thickness in TLE through experimental method in the complex industrial situation. However, the outlet temperature of TLE （TLEOT） can indirectly characterize the coking situation in TLE since the coke accumulation in TLE has great influence on TLEOT. Thus, the TLEOT could be a critical factor in deciding when to shut down the furnace to decoke. To predict the TLEOT, a paramewic model was proposed in this work, based on theoretical analysis, mathematic reduction, and parameters estimation. The feasibility of the proposed model was further checked through industrial data and good agreements between model prediction and industrial data with maximum deviation 2% were observed.

Research on Flexible Transfer Line Schematic Design Using Hierarchical Process Planning

Flexible transfer line(FTL)is now widely used in ma ny manufacturing domains to realize efficiently,high quantity and economic prod uction.These manufacturing domains include automobile,tractor,internal-combu stion engine,and so on.In today’s competitive business environment,it is vit ally important for machine tool manufacturers to design flexible transfer line m ore effectively and efficiently according to a wider variety of customer demand s.This paper proposes an approach to a bidding-based flexible transfer line sc hematic design system.By analyzing manual FTL design process,the architecture o f flexible transfer line schematic design system(FTLSDS)is established.The syst em consists:of four processes:part feature modeling,process planning,FTL fac i lity layout and FTL evaluation. For FTL schematic design.a five-level proces s planning strategy named hierarchical process planning method is proposed.This method includes selection of manufacturing feature machining operation;part se t-up planning,feature sequencing,operation sequencing and process plan genera ting.The major decision relies on setup planning.According to the proceeding o f the hierarchical process planning,the structure of reasoning is proposed base d on blackboard.Under this paradigm,a cooperative effort between a hybrid coll ection of knowledge sources is possible.Total reasoning task can be divided int o some subtasks,and recursive-reasoning system is formed.It is convenient for process planning with step-by-step solution.Meanwhile,the blackboard is use d as the global data exchange area during all reasoning process.By using modula r technology,special purpose machine tools can be designed more efficiently and rapidly.The framework of machine modular design system to support machine requ irement design for FTL is established.By synthesizing the FTL evaluation criter ia.five evaluation criteria of flexible transfer 1ine schematic design are take n into account.An exampie is supplied to demonstrate and verify the validity an d feasibility of flexible transfer line schematic design approach.

Research on Rapid Response Schematic Design for Flexible Transfer Line CAPP-Based

To meet the market requirements for Flexible Transf er Line (FTL), which consists of modular NC machining tools of high quality and co st saving, the methodologies and technologies of client-oriented FTL rapid resp onse schematic design CAPP-based, one of the key techniques, are presented in t his paper. In order to achieve this purpose, an integrated system for integrated design of CAD/CAPP/FTL with box-type parts is realized. In this paper, firstly the theory of the conceptual design of FTL based on CAPP is established and the software architecture is developed. The global-domain pr oduct model is put forward to meet with data representation. After the manufactu ring feature is analyzed and decomposed for machining operations, the feature-b ased part unified data model object-oriented is built. Secondly the knowledge- based CAPP system data model is established. The process planning unit model is formed by work element (WE), which is tool-cell based function abstraction meth od, and has unified layers with respect to designing and manufacturing. With WEs through dynamic response and simultaneous structure in process planning, the pr inciple solution for CAPP function system can be implemented. Lastly the mapping from process domain to module design domain is built. The unidirectional select ion process based on fuzzy matching technology is easily dealt with computer. Th e algorithm of decision with fuzzy synthetic evaluation method and technology is applied to estimate the feasibility of the results in local working procedure o f modular NC machine tools and make decision of designs in overall FTL, which co nsists of many different factors. The example shows that the rapid response desi gn in bidding-based FTL scheme design is realized.

An Operating Strategy for High-availability Multi-station Transfer Lines

Economic efficiency of a multi-station transfer line （TL） is evaluated directly by the quantity of parts produced; therefore, each single manufactured part counts. The contribution presents an approach which applies a reliability-adaptive operating strategy in combination with tool derating. It is the objective to hold the system harmonisation of tool changes as maintenance actions. The significant effectiveness of the approach is demonstrated by different configurations and contexts. The output-time function of a TL without reliability-adaptive control is compared with functions of a system with reliability-adaptive control.

Magnet lattice design of the SSRF electron-beam transfer lines

Under three-dimensional plane geometrical constraints ( X,Y,θ ), with two asymmetric achromatic sections, the combined three-section structural FODO-like magnet lattice design is adopted and finely optimized in the SSRF electron-beam transfer lines. The magnet lattice has high flexibility and robustness, and the Courant–Snyder parameters can be easily adjusted within a wide range to meet the requirements of transmission and injection for different operation modes of the linear accelerator, booster synchrotron, and storage ring. In this article, the main parameters of the linear optics design of the SSRF electron-beam transfer lines are described, involving the physical design criteria, the total geometrical layout, the magnet lattice, and the beam Courant–Snyder parameters matching. The studies of the variant beam dynamic simulation program calculations show that the design purpose of the efficient beam transmission and injection will be basically achieved.

Analysis of transmission efficiency of SSRF electron beam transfer lines

In this article, the main factors which influence transmission efficiency of the SSRF electron beam trans- fer lines are described, including physical requirements for magnet system, vacuum system, beam diagnostic system, trajectory correction system, etc. The dynamic simulation calculation and transmission efficiency analysis of the SSRF electron beam transfer lines are presented, and the studies show that the design purpose of efficient beam transmission and injection will be achieved.

The transfer line design for the HEPS project

Purpose The high energy photon source(HEPS),a 6-GeV synchrotron radiation facility with ultralow emittance,is under construction in China.Three transfer lines are designed for HEPS.One low-energy transfer line is used to deliver the 500 MeV beam provided by the linac to the booster.Two high-energy transfer lines are used to connect the booster and the storage ring to realize beam accumulation in the booster at 6 GeV.Method The design of the transfer lines is closely related to the layout and optics design of the storage ring,booster and linac.Based on the physics design of the storage ring,booster and linac,the design of the transfer lines has been adjusted.Results and conclusion In this paper,the considerations and design of the latest lattice of transfer lines are described.The design satisfies the requirements of the high efficiency transmission and injection.

CONCURRENT PRODUCTION ENGINEERING SYSTEM FOR BUFFER SIZE AND FLEXIBLE TRANSFER LINE LAYOUT DESIGN

In this paper we propose a COncurrent Production Engineering System （COPES） for the flexible transfer line （FTL） layout design in a restricted area. COPES first determines the buffer size in front of the bay of each machine tool in the FTL and then initializes a computer aided design （CAD） system to draw the FTL in a restricted area. We develop a set of modules systems which have been integrated into a single framework, in accordance with the practice of concurrent engineering. Concurrent engineering involves the cooperation of these activities. It＇s expected that the developed COPES can improve the cooperation between production engineers＇ and the plant designer. This can be done by enabling the production engineers＇ to make better decision regarding FTL buffer size.

A Liability Division Method for Harmonic Pollution Based on Line-Transferred Power Components

The existing liability division methods for harmonic pollution are either inexplicit or incomplete in physical meaning. To compensate these defects, two new methods are proposed based on line-transferred power components in this paper. At first, all harmonic sources are represented by ideal equivalent current source, line current components and bus voltage components of a source are determined by stimulation of this source with all other sources disabled. Then, the line-trans- ferred power component owing to a source under all sources action together is determined by the theory of line-transferred power components, and called source’s line-transferred power component. At last, the liability of a source for line-end harmonic pollution is divided by two methods: the ration of the source’s line-transferred active power component to the total line-transferred power, and the ration of projection of the source’s line-transferred complex power component to absolute value of the total line-transferred complex power. These two methods are taken into account not only harmonic voltage but also harmonic current in the liability division. Simulation results show that the proposed liability division method based on active power component is the most effective and ideal one.

Scheme for realizing quantum computation and quantum information transfer with superconducting qubits coupling to a 1D transmission line resonator

This paper proposes a simple scheme for realizing one-qubit and two-qubit quantum gates as well as multiqubit entanglement based on de-SQUID charge qubits through the control of their coupling to a 1D transmission line resonator （TLR）. The TLR behaves effectively as a quantum data-bus mode of a harmonic oscillator, which has several practical advantages including strong coupling strength, reproducibility, immunity to 1/f noise, and suppressed spontaneous emission. In this protocol, the data-bus does not need to stay adiabatically in its ground state, which results in not only fast quantum operation, hut also high-fidelity quantum information processing. Also, it elaborates the transfer process with the 1D transmission line.

On the Line Formation in Stellar Magnetized Atmospheres

The line formation process in stellar magnetized atmospheres is studied by observing the wavelength- dependence of Stokes contribution functions. The influence of magnetic field on the escape line photon distribution and line absorption is obtained by comparing with the null magnetic field case. Two models airs adopted. One assumes limited distributions of both the line absorption and magnetic field where a hypothetical magneto-sensitive line is formed. The other is a model atmosphere of sunspot umbra in which MgI 5172.7 forms. It is found that the magnetic field influences the formation region of Stokes I at wavelengths sufficient close to the Zeeman splitting points ±△ H. The formation regions at wavelengths far away from the Zeeman splitting points generally show a non-magnetic behaviour. Further, if the line core is split by the Zeeman effect, the line formation core introduced in the previous paper disappears. On the other hand, Stokes Q, U, V at each wavelength within the line form in the same layers where both the line absorption and magnetic field are present in the models accepted for the lines used. When the line absorption and magnetic field ubiquitously exist, the formation regions of the T peaks or valleys of Stokes Q, U and those of σ of Stokes V generally cover the widest depth range. It is pointed out that such a study is instructive in the explanation of solar polarized filtergrams. It can tell us at each observation point where the received line photons of wavelengths within the bandpass come from and where their polarization states are formed or give us the distributions of these photons as well as their polarization intensities. Thus a three-dimensional image can be constructed for a morphologic study of the observed area from serial filtergrams.

Key Properties of Solar Chromospheric Line Formation Process

The distribution or wavelength-dependence of the formation regions of frequently used solar lines, Hα, Hβ, CaIIH and Car18542, in quiet Sun, faint and bright flares is explored in the unpolarized case. We stress four aspects characterising the property of line formation process: 1) width of line formation core; 2) line formation region; 3) influence of the temperature minimum region; and 4) wavelength ranges within which one can obtain pure chromospheric and photospheric filtergrams. It is shown that the above four aspects depend strongly on the atmospheric physical condition and the lines used. The formation regions of all the wavelength points within a line may be continuously distributed over one depth domain or discretely distributed because of no contribution coming from the temperature minimum region, an important domain in the solar atmosphere that determines the distribution pattern of escape photons. Cm the other hand, the formation region of one wavelength point may cover only one heigh t range or spread over two domains which are separated again by the temperature minimum region. Different lines may form in different regions in the quiet Sun. However, these line formation regions become closer in solar flaring regions. Finally, though the stratification of line-of-sight velocity can alter the position of the line formation core within the line band and result in the asymmetry of the line formation core about the shifted line center, it can only lead to negligible changes in the line formation region or the line formation core width. All these results can be instructive to solar filtering observations.

RETROVIRAL MEDIATED EFFICIENT TRANSFER ANDEXPRESSION OF MULTIPLE DRUG RESISTANCE GENE TO HUMAN LEUKEMIC CELLS

Objective: To investigate retroviral-mediated transfer and expression of human multidrug resistance (MDR) gene MDR1 in leukemic cells. Methods: Human myeloid cells, K562 and NB4, were infected by MDR retrovirus from the producer PA317/HaMDR, and the resistant cells were selected with cytotoxic drug. The transfer and expression of MDR1 gene was analyzed by using polymerase chain reaction (PCR), flow cytometry (FCM) and semisolid colonies cultivation. Results: The resistant cells, K562/MDR and NB4/MDR, in which integration of the exogenous MDR1 gene was confirmed by PCR analysis, displayed a typical MDR phenotype. The expression of MDR1 transgene was detected on truncated as well as full-length transcripts. Moreover, the resistant cells were P-glycoprotein postiive at 78.0% to 98.7% analyzed with FCM. The transduction efficieny in K562 cells was studied on suspension cultures and single-cell colonies. The transduction was more efficient in coculture system (67.9%-72.5%) than in supernatant system (33.1%~46.8%), while growth factors may improve the efficiency. Conclusion: Retrovirus could allow a functional transfer and expression of MDR1 gene in human leukemia cells, and MDR1 might act as a dominant selectable gene for coexpression with the genes of interest in gene therapy.

Magneto-induced Line Broadening of Magneto-sensitive Lines in Solar Magnetized Atmospheres

We analyze the spectral line broadening of those magneto-sensitive lines in solar magnetized atmospheres. The broadening at the line wings is due to the increase of the effective width of energy levels involved in Zeeman splitting,and the broadening at the line core also originated in Zeeman splitting under the condition that the Zeeman components are mixed. Therefore, the magneto-induced or Zeeman broadening take effects on the whole line. The observed Stokes parameter data in a sunspot and outside it acquired by Solar Stokes Spectrum Telescope （S^3T） are analyzed for the demonstration of this mechanism, and the Zeeman broadening rates are calculated for Fe16302.5 under some assumptions.Our result shows that the broadening is increased as the magnetic field strength becomes stronger, but the rate of increase at the line core is decreased as the field strength increases, while the rate at the wing does not show such an obvious regularity. The broadening is more effective in the line core than in the wings.

RETROVIRUS-MEDIATED TNF-α GENE TRANSFER INTO TCA8113 CELLS

Objective To investigate whether TNF-α gene-modified Tca8113 cells (Tca8113/TNF-α) canbe used as vaccine for oral squamous cell carcinoma. Methods TNF-α gene was transduced into Tca8113 cellsin vitro with retroviral vector carring genes for both TNF-α and NeoR. After that, presence and expression of exoge-nous gene in the transgenic cells, expression of HLA antigen on the cells, expression of TNF-α and survival rate ofthe cells after irradiation and cryopreservation, and mutagenic activity of the cells were analyzed by PCR technique,EL1SA technique, FACS technique, 60Co irradiation inactivation test, cryopreservation test, and Ames test, respec-tively. Results The presence of both TNF-a and NeoR gene and expression of TNF-α gene were demonstrated intransgenic cells. The levels of the HLA-A, B, C, DR expressed by Tca8113/TNF-α were higher than by the parentalcells. Tca8113/TNF-α continued to secrete TNF-α for 14 d, there was a secretion peak time from d4 to d6;and, allthe cells died by dl4 after irradiation. The Level of TNF-α secreted by Tca8113/TNF-α cryopreserved for 48 h wasno different from that cryopreserved for 1 week after irradiation, the level of TNF-α secreted by the cryopreservedcells was just a little lower than that secreted by the noncryopreserved cells. Both DNA and supernatant of the cellshave no mutagenic activity. Conclusion TNF-α gene can be transduced into Tca8113 cells with retroviral vec-tor, and the cells can express TNF-α. Expression of HLA 1,11 antigens on Tca8113 cells can be increased by TNF-αgene transduction. Irradiation is a reliable inactivation method, and cryopreservation is a feasible conservationmethod for Tca8113/TNF-α. Ames test result indicate that Tca8113/TNF-α has no mutagenic activity.

基于近红外光谱模型转移的牛奶蛋白检测方法研究

目的研究基于近红外光谱模型转移的牛奶蛋白检测方法。方法分别采用实验室与在线检测近红外光谱仪采集生产过程中原料奶样品的近红外光谱,研究斜率截距法(slope/bias,S/B)、分段直接标准化(piecewise direct standardization,PDS)算法、Shenk’s方法在不同仪器测量光谱之间模型转移应用,优化模型参数,提高实验室仪器建立的校正模型应用于在线光谱仪器的预测精度。结果经过Shenk’s算法转移,主从机的光谱平均差异降低为0.0075,光谱校正率达到98.95%。利用模型转移方法与偏最小二乘模型结合,将实验室分析光谱仪建立的模型用于生产在线光谱仪测量光谱预测,显著提高了牛奶中蛋白质含量预测准确度,不同仪器之间模型预测相对均方根误差从5.52%下降到2.03%。结论本研究的方法实现了实验室分析与在线检测仪器测量光谱及定量分析模型转移共享,为近红外在线检测的智能化改进提供了基础。

Initiation of two ovarian cell lines from Fugu rubripes(Temminck et.Schlegel)

The ovary is an excellent system for studying stem cell renewal and differentiation, which is under the control of ovarian somatic cells. In order to understand oogenesis in Fugu rubripes （Temminck et. Schlegel） as a marine fish model of aquaculture importance, we established cell lines called TSOC 1 and TSOC2 from a juvenile ovary of this organism. TSOC1 is composed of spindle epithelial-like cells, while the other is cobblestone-like ceils. Therefore, TSOC1 and TSOC2 appear to consist of ovarian somatic cells. Growth requirement condition was investigated including temperature, concentration of FBS and pH. Significant fluorescent signals were observed after TSOC1 and TSOC2 cells were transfected with pEGFP-N3 vector, indicating its potential utility for genetic manipulation such as gene function studies. It is shown that these cell lines are effective for infection by the turbot reddish body iridovirus and flounder lymphosystis disease virus as evidenced by the appearance of cytopathic effect and virus propagation in the virus-infected cells, and most convincingly, the observation of viral particles by electron microscopy, demonstrating that TSOC1 and TSOC2 are suitable to study interactions between virus and host cells. It is believed that TSOC1 and TSOC2 will be useful tools to study sex-related events and interactions between primordial germ cells and oogonia cells during oogenesis. Therefore, establishment of ovary cell lines from Fugu rubripes seems to be significant for those research areas.

低频导波检测技术在输油场站应用的效果分析

本文主要是对低频导波检测技术原理和应用进行分析,进而选取本次最优开挖验证点,通过MsS长距离超声导波检测仪在姬塬外输总站管网腐蚀检测过程中的应用效果分析,判断其应用效果具有哪些局限性和优缺点,为后续输油场站常规检测工作提供参考依据。

基于标准火灾曲线和热释放率的衬砌温度分布数值计算研究

为探明火灾下衬砌温度的分布特性,基于隧道火灾-衬砌辐射对流传热数学模型建立了衬砌温度数值计算方法,并对HC标准火灾曲线和30 MW火灾热释放率火灾工况进行计算分析。结果表明,标准火灾曲线最高温度普遍大于目前我国规范的要求。采用火灾温度作为衬砌壁面边界条件将显著增大衬砌温度荷载,2小时HC火灾曲线和30 MW火灾工况衬砌最高温度分别为778℃和351℃。标准火灾曲线工况衬砌内部的高温影响范围和高温值均显著大于30 MW火灾工况。