A study on the treatment of chloasma with moxibustion based on the theory of“Yang transforming Qi,and Yin shaping”

Background:“Yang Transforming Qi and Yin shaping”comes from“Plain Question Yin and Yang should be like the theory”.Chinese medicine believes that the imbalance of yin and yang is the cause of human diseases.One of the strengths of TCM in treating diseases is holistic regulation.The theory of“Yang transforming Qi,and Yin shaping”implies a strong holistic view.Chloasma,one of the common skin diseases,seriously affects the physical and mental health of patients due to its unclear etiology,difficult treatment and easy recurrence.The occurrence and development of chloasma are closely related to internal organs.This paper is based on the theory of internal meridian,“Yang transforming Qi,and Yin shaping”which attaches importance to the concept of“Yang Qi”,from a new understanding of the pathogenesis etiology of chloasma.Methods:The author believes that the incidence of the disease is the deficiency of Yang Qi,which can’t promote the movement of Qi and blood to nourish the face,resulting in tangible material condensation,so proposes that this disease needs to be promoted by Yang transforming Qi and warm to dissipate.Moxibustion belongs to the fire,and its warming effect can dissipate the tangible evil.Results:Combined with clinical practice and the theory of internal meridian,the author elaborated that moxibustion is one of the effective methods for treating chloasma,which provides a new way of thinking for the treatment of chloasma.Conclusion:“Yang Transforming Qi and Yin shaping”can be used to guide the treatment of chloasma.

Discussion on the Application of Warm Yang to Promote Qi Transformation in Acne Mastitis from“Yang Promotes Qi Transformation and Yin Promotes Forming”

“Yang promotes Qi transformation and Yin promotes forming”maintains the normal progress of human life activities,which is an important embodiment of human vitality.The dysfunction of“Yang promotes Qi transformation and Yin promotes forming”leads to the coagulation of pathological products such as phlegm and blood stasis in the breast meridian,resulting in the occurrence of acne mastitis.In clinical treatment,we should take“warm Yang to promote Qi transformation”as the treatment principle,and add or subtract according to the specific situation.

The Reality and Application of Yin and Yang

Ancient Chinese philosophers discovered Yin and Yang and the laws of Yin and Yang movement during their exploration and practice of nature more than two thousand years ago, and applied them to life, science, philosophy and medicine, playing an important role in the achievement of ancient Chinese civilization. Through historical changes, yin and yang have gradually been regarded as a concept or theory, thus making it difficult for people to understand the connotation of Yin-Yang and make new discoveries and progress. Nowadays, many scholars in China and the West are interested in studying the treasures of ancient Chinese civilization. We illustrate the actual function of Yin and Yang by explaining the essential state of matter, the law of physical movement, the transformation of energy, and then illustrate the practical application in life and science. In conclusion, yin-yang is a key to unlocking the treasures of traditional Chinese civilization, which can help to bring into play its original values, and continue to provide new insights and directions for the development of modern science and the advancement of humanities.

从“阳化气,阴成形”探讨慢性咳嗽之因机证治

慢性咳嗽是以咳嗽为主症或唯一症状、病程持续8周以上的呼吸系统疾病。慢性咳嗽病因复杂,病程较长,病势缠绵,且极易复发。西医诊断该病过程繁琐,治疗手段有限,而中医药以整体观念和辨证论治思想为指导,在缓解临床症状、预防疾病复发方面具有独特优势。该文以“阳化气,阴成形”为抓手,分析阴阳在慢性咳嗽因机证治全周期的重要意义,认为慢性咳嗽之病机关键为“阳化气,阴成形”功能失衡,以肺之气血失和、阴阳虚损为本,阳化而气行不畅、周流有碍,阴变而凝结停滞、壅塞肺络为标。治疗上,需要补肺、脾、肾阴阳之不足,泄气滞、水湿、痰饮、瘀血、热毒之有余,以恢复“阳化气,阴成形”之平衡。具体用药方面,主张以偏纠偏,以药物气味之偏性纠正人体阴阳之偏颇。另附典型医案二例,加以验证说明,以期为中医药防治慢性咳嗽提供新的诊疗思路和方法。

基于“阳化气,阴成形”理论辨治痿证

津气两伤是痿证的病变基础,亦是“阳化气,阴成形”失衡的结果。阳化气不足,阴成形失衡,而致脏腑功能失调,水饮痰瘀内生,四肢九窍失养,发为痿证。本文基于“阳化气,阴成形”理论,探讨高颖教授采用助阳化气法治疗阳化气不足的重症肌无力,益肾调形法治疗阴成形失衡的多发性硬化,阴阳双补法治疗阴阳俱损的运动神经元病。治疗痿证,需审证求因,明辨阴阳,调整偏颇,在疾病早期给予中医药治疗,以延缓疾病演变进程、改善预后。

基于“阳化气,阴成形”论治癌性腹水临床经验探讨

癌性腹水作为中晚期肿瘤的常见并发症之一,临床以腹部胀满和呼吸窘迫为主要症状,多见于晚期卵巢、胰腺和胃肠道恶性肿瘤等腹腔脏器恶性肿瘤患者。其发展速度快,病情进行性加重,一旦出现癌性腹水,患者的中位生存期将缩短至数月甚至数周,严重影响肿瘤患者的后续治疗及生活质量。癌性腹水的治疗至今仍是临床一大难题。“阳化气,阴成形”是《黄帝内经》中关于阴阳生理病理状态的重要论述,阳主“动”而流散以化气,阴主“静”而凝聚以成形,二者调和一致则为平人,若平衡被打破则百病由生。郭立中教授立足临床,结合古医籍和临床经验,提出“阳化气”不及、“阴成形”太过与癌性腹水的发生、发展密切相关。其中,“阳化气”不及是发病之本,“阴成形”太过是发病之标。肺、脾、肾阳虚化气不足,水液运化失常,水湿结聚,水为寒邪,寒性收引凝滞,易致血脉凝结,血凝又加重水湿留而不行,水湿、血瘀停聚腹腔形成癌性腹水。阳虚、水湿、血瘀是关键病因,病性为本虚标实,导师以扶阳消阴为治疗总则,重视扶肺、脾、肾阳气以固其本,消水湿瘀血以治其标,并根据疾病不同时期的病机特点在治疗上讲求次第,灵活变通,并配合外治法,临床收效显著。

基于调和阴阳理论针灸组方治疗老年肝郁化火型失眠

目的探讨基于调和阴阳理论针灸组方治疗老年肝郁化火型失眠的临床疗效。方法将老年肝郁化火型失眠患者80例按照随机数表法分为对照组与观察组,各40例。对照组采用西药治疗,观察组在对照组基础上联合调和阴阳法针灸治疗。观察2组治疗前后中医证候积分、多导睡眠图、匹兹堡睡眠质量指数量表(PSQI)、失眠严重程度指数量表(ISI)、爱普沃斯嗜睡量表(ESS)、血清单胺递质指标5-羟色胺(5-HT)、谷氨酸(GA)、神经肽Y(NPY)、γ-氨基丁酸(GABA)变化,并评价2组治疗总有效率和治疗安全性。结果观察组治疗后各项中医证候积分、睡眠潜伏期、觉醒时间、PSQI评分、ISI评分、ESS评分均低于对照组(P<0.05),睡眠总时间、快速眼动睡眠期、5-HT、GA、NPY、GABA指标均高于对照组(P<0.05);观察组治疗总有效率(92.5%,37/40)高于对照组(77.5%,31/40)(P<0.05);2组不良反应发生情况比较,差异无统计学意义(P>0.05)。结论基于调和阴阳理论的针灸组方联合西药治疗老年肝郁化火型失眠疗效明显,能够缓解患者不适症状,减轻日间嗜睡程度,调节神经递质表达,改善睡眠质量,且不良反应少。

基于“阳化气,阴成形”从温阳法论治肺部结节

《素问·阴阳应象大论篇》中记载的“阳化气,阴成形”高度概括了人体脏腑组织的生命活动,阴阳失衡是导致疾病发生的关键。本文通过分析“阳化气,阴成形”理论,发现肺部结节发生和发展的核心机制是“阳化气不足,阴成形太过”。结节乃有形之体,是机体阳气亏虚,精血津液运行障碍,化为痰饮瘀毒,敛聚局部而生;结节本质乃阳虚阴结,本虚标实,本虚即脾肾阳虚,标实即痰饮、瘀血、浊毒。中医学强调治病求本,故基于“阳化气,阴成形”理论,以温阳化气为基本治则,探讨温阳法在肺部结节治疗中的应用,分别从温阳补肾、温阳健脾、温阳化痰、温阳活血、温阳解毒和温阳散结等角度辨证施治,以防“阴成形太过”,使“阳化气”之功能正常发挥,则机体阴阳平衡,百病不生。

吕晓东论治肺结节经验撷菁

总结吕晓东教授运用中医药治疗肺结节的临床经验和学术思想。吕晓东教授基于阳化气,阴成形的两个基本生理功能观,考察肺结节的发生、发展的病理环节,认为肺结节形成之机理复杂,病因纷繁,为阴分邪气积聚为肺,但病性基础变化总体以阳虚为关键,病理以气滞痰瘀胶着于肺络为核心。在肺络病的指导原则下,运用扶阳抑阴、通补肺络的手段,恢复阳主阴从,一气周流,肺络调和的生理状态,从而调复肺脏的异常功能状态、消弭肺结节的病理改变,恢复身心健康的目的,临床每获良效,具有推广应用的价值。

Mechanism underlying treatment of diabetic kidney disease using Traditional Chinese Medicine based on theory of Yin and Yang balance

The pathogenic mechanism of diabetic kidney disease(DKD) is complex. The development of DKD cannot be fully explained by a single mechanism.Traditional Chinese Medicine(TCM) has been applied extensively for the treatment of DKD in China.However, studying the mechanism of DKD using theories and methods that are appropriate for TCM characteristics and searching for theoretical bases for TCM clinical application are topics that still need to be explored and researched. Activation of the transforming growth factor(TGF)-β1/Smad and PI3 K/Akt/mTOR signaling pathways functions as a self-protection mechanism against renal microinflammation in DKD. However, the persistent abnormal overactivation of reactions causes secondary cell dysfunction, cell apoptosis, increased extracellular matrix(ECM) secretion, and eventually renal fibrosis. During this process, the dysregulation of self-balance among a variety of signaling pathways and the loss of self-feedback regulatory mecha-nisms downstream of these signaling pathways are critical causes of the occurrence and development of DKD. TCM may both inhibit the expression or activation of "hyperactive" signaling pathways(NFB, Smad3, and PI3 K/Akt/mTOR) and increase the expression or activation of "deficient" signaling pathways(Smad7 and PTEN) to restore balance to cells with an abnormal pathophysiological status and achieve the goal of DKD treatment.

从阴阳气化探讨糖尿病“郁热虚损”四期病机转化规律

糖尿病是一种慢性代谢性疾病,中医认为血糖属人体精微物质,阴阳气化高度概括了机体物质、能量的转化方式,具体运动方式是“阳化气,阴成形”,只有阴阳气化的运动相协调,血糖才能正常代谢,否则余而为害,逐渐发展为糖尿病。“郁、热、虚、损”是对糖尿病全过程中医病机的概括总结,笔者试从阴阳气化的角度探讨糖尿病全程的病机转化规律,以期为临床治疗提供新的思路。

从“阳化气,阴成形”探讨扶阳法在肿瘤临床中的应用

“阳化气,阴成形”源于《素问·阴阳应象大论》。“阳化气”不足而“阴成形”太过会导致气滞血瘀、痰湿凝滞、水饮内停,使病理有形之物积聚而发为肿瘤。因此,“阳化气”不足而“阴成形”太过是肿瘤的核心发病机制。基于此,提出扶阳法为肿瘤的临床防治大法。在预防方面,需强身健体,劳逸结合,饮食有节忌偏嗜,注意调畅情志;在治疗用药方面,可分为温阳法、通阳法、温通法三法。

从“阳化气,阴成形”辨治癌性疼痛探析

以“阳化气,阴成形”理论阐述癌性疼痛的病机,并探析癌性疼痛的辨治,认为“阳化气”“阴成形”的太过与不及是癌性疼痛的发生机制,通过调节阴阳以指导癌性疼痛的辨治,补虚损、散阴形、抗肿瘤三法来补虚治痛,散消阴结,消瘤治痛,从而实现阴阳平衡。

基于“阳化气,阴成形”探讨冠状动脉慢性完全闭塞的中医论治

本研究基于“阳化气,阴成形”理论,探讨冠状动脉慢性完全闭塞(CTO)的中医病因病机,认为阳虚失运-化气不足-血脉不荣、阴邪凝结-成形太过-血脉不通是CTO的关键病机,以阳气虚衰为本,阴邪(湿邪、痰浊、水饮、血瘀)凝滞为标。治疗上提出温阳化气法是治疗CTO的总则,温肺阳以化宗气,温脾阳以化中气,温肾阳以化元气,结合阴邪偏盛,辅以燥湿、祛痰、化饮、逐瘀之法,以达到缓解症状、改善预后之功,并附验案1则,以期为CTO的中医治疗提供新的思路。

基于“阳化气,阴成形”理论探析陈永灿辨治慢性萎缩性胃炎伴肠上皮化生经验

慢性萎缩性胃炎伴肠上皮化生是慢性胃炎发展到胃癌的必经阶段。陈永灿认为,“阳化气,阴成形”理论可诠释慢性萎缩性胃炎伴肠上皮化生的发展及诊疗过程。“阳化气”不足导致“阴成形”太过,使脾胃生理机能改变,从而发展为慢性萎缩性胃炎伴肠上皮化生的病理过程。通过“阳化气,阴成形”理论对本病的病机进行探析,临床治疗首先辨别阴阳状态,提出扶阳气、祛阴浊的治疗原则,以标本兼治。

基于“阳化气,阴成形”理论探讨原发免疫性血小板减少症辨治

原发免疫性血小板减少症(ITP)是以出血为主要临床表现的获得性自身免疫性疾病。普遍认为ITP为巨核细胞产板不良或(和)机体免疫异常介导的血小板破坏增加,导致血小板数量减少,故ITP关键在于血小板的生成与破坏。ITP属于中医“血证”“紫癜病”范畴,中医对此阐述较多。文章基于“阳化气,阴成形”理论,从生成与破坏角度对ITP的辨治进行探讨,将血小板生成减少与“阴成形”不足相联系,血小板破坏过多与“阳化气”太过相联系,分析得出“血小板生成”属阴精化血范畴,“血小板破坏”属阳气耗散或化物异常范畴,基于此确定将“泻火”“滋阴”等治疗方法应用于临床实践,为探索辨治ITP提供新思路。

基于“阳化气,阴成形”理论浅谈中西医结合治疗肺癌机制

肺癌是临床上最常见的恶性肿瘤之一,其发病率逐年上升。自古代起,黄帝内经及历代医家就对肺癌提出了有效的治疗法则。他们认为“阳化气”不足,而“阴成形”太过,是导致肺癌发病的重要原因之一。文章旨在对“阳化气,阴成形”理论在中西医结合治疗肺癌方面的研究进行综述,以期为肺癌的治疗和研究提供新的思路。

基于“阳化气,阴成形”辨治肺结节经验

“阳化气,阴成形”理论认为,肺结节基本病机为阳化气不足致气化失司、气机失调,阴成形太过致水液失调、痰瘀互结;治疗原则为温阳抑阴、固本培元。“阳化气,阴成形”理论对中医论治肺结节具有良好的指导意义。

基于“阳化气,阴成形”理论探究多囊卵巢综合征中医病机与治疗思路

多囊卵巢综合征(PCOS)是一种好发于18~35岁女性的内分泌障碍及代谢紊乱并存的疾病,属“月经后期”“崩漏”“闭经”等范畴。“阳化气,阴成形”是气化的两个过程,能够体现阴阳生理功能,通过探析PCOS病变过程中的阴阳变化,进一步明确其基本病机。笔者发现PCOS患者多属阳化气不足,脾肾亏虚;阴成形太过,致痰瘀互结,继而阴阳失和。临证治疗应循阴阳为本,调脾温肾,疏肝和枢,以期阴平阳秘。

章勤从“阳化气阴成形”论治泡膜发育异常不孕经验

[目的]总结章勤教授调治以卵泡和子宫内膜发育异常为主导致的不孕症患者的经验。[方法]通过整理章勤教授的临床医案,分析其基于“阳化气阴成形”理论对不孕症主要病机的理解,梳理概括其诊治卵泡和子宫内膜发育异常的临床思路,归纳总结用药经验,并在文末举一则医案佐证。[结果]章勤教授认为,不孕首当责之于肾,“阳化气阴成形”的失常是根本原因。从月经周期出发,根据阴阳变化调治,经前黄体期当补肾助阳,以促经行;行经期当因势利导,温肾育阴使胞宫血脉通畅,启故从新;经后卵泡期当滋养卵泡和内膜,以育生化;经间排卵期当养阳梳理,以促排卵。文末所附一则医案为女性不孕症伴有月经过少的患者,章勤教授运用“阳化气阴成形”理论,分期论治,效如桴鼓。[结论]章勤教授运用“阳化气阴成形”理论调治卵泡及内膜发育异常患者,提高子宫内膜容受性,并使得精卵发育成熟,顺利排出,胎孕得成,疗效显著,为临床治疗相关疾病提供新的思路。