AIM： To describe the morphological changes of the lamina cribrosa （LC） in patients with optic nerve compression. METHODS： Cross-sectional study. Twenty eyes with optic nerve compression, affected by Graves＇ opht...AIM： To describe the morphological changes of the lamina cribrosa （LC） in patients with optic nerve compression. METHODS： Cross-sectional study. Twenty eyes with optic nerve compression, affected by Graves＇ ophthalmopathy （GO） were compared with 18 refractive error-matched healthy eyes. The following examinations were performed： best-corrected visual acuity （BCVA）, intraocular pressure, optic nerve echography, visual field, SD-OCT including the retinal nerve fiber layer （RNFL）, ganglion cell complex （GCC）, and LC thickness and extent. RESULTS： A-scan revealed significant differences in the subarachnoid space （SAS） between the affected and control groups. LC thickness and LC area were 233 pm （SD 23） and 0.41 mm2 （SD 0.19）, respectively. Average GCC thickness （P=-0.0005）, LC thickness （P=-0.001）, MD （P=-0.001） and PSD （P=-0.001） differed significantly between the two groups; whereas LC area （P=-0.2） and average RFNL （P=-0.1） did not. CONCLUSION： Optic nerve compression reduces the SAS thereby altering the morphology of LC thickness and causing GCC damage.展开更多
Objective: To evaluate the efficacy of Cotrel-Dubeusset （CD） instrumentation combined with translaminar facet joint screw （TLS） in the treatment of thoracolumbar fracture.Methods: A total of six L2-L4 spines were ...Objective: To evaluate the efficacy of Cotrel-Dubeusset （CD） instrumentation combined with translaminar facet joint screw （TLS） in the treatment of thoracolumbar fracture.Methods: A total of six L2-L4 spines were used to establish unstable fracture model with three-dimensional range of motion （ROM） of the spines measured. Fixation with CD and fixation with CD combined with translaminar facet joint screw were achieved to compare their stability. Thirty cases of thoracolumbar fracture, in whom the anterior edge of vertebral body was compressed to 59% and the posterior edge compressed to 88%, were treated by pedicle screw fixation combined with TLS. Among them, 19 received posterolateral or anterior-posterior bone graftingResults: There was significant difference in ROM between the two techniques except that in extension. In Group CD+TLS, ROM was （5.38）% lower, lateral bending （4.91）% lower and axial rotation （11.85）% lower than those in Group CD respectively. In the clinical group, the average anterior edge restored to 97% and posterior edge to 98%. The duration of follow-up was 5-24 months （mean, 10 months）. The rate of correction loss on the anterior edge was （4.5）%. Among the 19 cases of bone grafting, all of them achieved bony fusion （mean fusion time, （4.3） month） with a correction loss rate of （3.4）%.Conclusions: In the treatment of thoracolumbar fracture, pedicle screw fixation combined with TLS can strengthen the stability of pedicle screws, especially anti-rotation stability and enhance fusion rate and reduce correction loss.展开更多
基金ACKNOWLEDGEMENTS We thank Jean Ann Gilder(Scientific Communication srl.,Naples,Italy)for editing this article.
文摘AIM： To describe the morphological changes of the lamina cribrosa （LC） in patients with optic nerve compression. METHODS： Cross-sectional study. Twenty eyes with optic nerve compression, affected by Graves＇ ophthalmopathy （GO） were compared with 18 refractive error-matched healthy eyes. The following examinations were performed： best-corrected visual acuity （BCVA）, intraocular pressure, optic nerve echography, visual field, SD-OCT including the retinal nerve fiber layer （RNFL）, ganglion cell complex （GCC）, and LC thickness and extent. RESULTS： A-scan revealed significant differences in the subarachnoid space （SAS） between the affected and control groups. LC thickness and LC area were 233 pm （SD 23） and 0.41 mm2 （SD 0.19）, respectively. Average GCC thickness （P=-0.0005）, LC thickness （P=-0.001）, MD （P=-0.001） and PSD （P=-0.001） differed significantly between the two groups; whereas LC area （P=-0.2） and average RFNL （P=-0.1） did not. CONCLUSION： Optic nerve compression reduces the SAS thereby altering the morphology of LC thickness and causing GCC damage.
文摘Objective: To evaluate the efficacy of Cotrel-Dubeusset （CD） instrumentation combined with translaminar facet joint screw （TLS） in the treatment of thoracolumbar fracture.Methods: A total of six L2-L4 spines were used to establish unstable fracture model with three-dimensional range of motion （ROM） of the spines measured. Fixation with CD and fixation with CD combined with translaminar facet joint screw were achieved to compare their stability. Thirty cases of thoracolumbar fracture, in whom the anterior edge of vertebral body was compressed to 59% and the posterior edge compressed to 88%, were treated by pedicle screw fixation combined with TLS. Among them, 19 received posterolateral or anterior-posterior bone graftingResults: There was significant difference in ROM between the two techniques except that in extension. In Group CD+TLS, ROM was （5.38）% lower, lateral bending （4.91）% lower and axial rotation （11.85）% lower than those in Group CD respectively. In the clinical group, the average anterior edge restored to 97% and posterior edge to 98%. The duration of follow-up was 5-24 months （mean, 10 months）. The rate of correction loss on the anterior edge was （4.5）%. Among the 19 cases of bone grafting, all of them achieved bony fusion （mean fusion time, （4.3） month） with a correction loss rate of （3.4）%.Conclusions: In the treatment of thoracolumbar fracture, pedicle screw fixation combined with TLS can strengthen the stability of pedicle screws, especially anti-rotation stability and enhance fusion rate and reduce correction loss.
