Effects of Different Sowing and Transplanting Time on Quality and Economic Benefit of Tobacco Variety Yunyan 105

In order to provide references for popularization and application of tobacco variety Yunyan 105,a field experiment was conducted to explore the effects of different sowing and transplanting time on agronomic traits,economic benefit and quality of Yunyan 105. Results showed that the agronomic characters,quality traits and economic benefit of the tobacco were relatively fine with sowing time February 4-14 and transplanting time April 1-10. Index scores of the physical properties of tobacco leaves were greater than 80 scores with sowing time February 14 and transplanting time April 10. The comprehensive index of conventional chemical compositions was 0. 39-0. 73. The harmony of conventional chemical compositions of lower leaves was the best with the comprehensive index of 0. 59 when the sowing time and transplanting time were February 4 and April 1 respectively. As for the middle and upper leaves the comprehensive indexes were respectively 0. 71 and 0. 73 with the sowing time February 14 and transplanting time April 10. The sensory evaluation of smoking quality and economic benefit were February 14 sowing and April 10 transplanting better,its taste of the tobacco leaves was pure and mild,the irritancy and the strength was less,the aftertaste was better,and the output value reached the highest 4 271. 17 yuan/667 m^2. The various sowing and transplanting time had no significant influence on appearance quality of tobacco leaves. The suitable sowing and transplanting time of Yunyan 105 was February 4-14 and April1-10 respectively in Xuanwei tobacco-growing area.

When is The Best Time of Stem Cell Transplantation for Treating Acute Myocardial Infarction──A Brief Meta-analysis of Current Clinic Trials

The best time of stem cells transplantation for treating acute myocardial infarction (AMI) is still to be followed with interest and a focus issue for clinical cardiologist. A brief meta-analysis of clinical trials about timing-window and therapeutic effects of stem cell transplantation for treating AMI will be made out in this article.

Impact of cirrhosis-related complications on posttransplant survival in patients with acute-on-chronic liver failure

Background:Acute-on-chronic liver failure(ACLF)is a life-threatening syndrome defined as acute decompensation in patients with chronic liver disease.Liver transplantation(LT)is the most effective treatment.We aimed to assess the impact of cirrhosis-related complications pre-LT on the posttransplant prognosis of patients with ACLF.Methods:This was an observational cohort study conducted between January 2018 and December 2020.Clinical characteristics,cirrhosis-related complications at LT and patient survival post-LT were collected.All liver recipients with ACLF were followed for 1 year post-LT.Results:A total of 212 LT recipients with ACLF were enrolled,including 75(35.4%)patients with ACLF-1,64(30.2%)with ACLF-2,and 73(34.4%)with ACLF-3.The median waiting time for LT was 11(4-24)days.The most prevalent cirrhosis-related complication was ascites(78.8%),followed by hepatic encephalopathy(57.1%),bacterial infections(48.1%),hepatorenal syndrome(22.2%)and gastrointestinal bleeding(11.3%).Survival analyses showed that patients with complications at LT had a significantly lower survival probability at both 3 months and 1 year after LT than those without complications(all P<0.05).A simplified model was developed by assigning one point to each complication:transplantation for ACLF with cirrhosis-related complication(TACC)model.Risk stratification of TACC model identified 3 strata(≥4,=3,and≤2)with high,median and low risk of death after LT(P<0.001).Moreover,the TACC model showed a comparable ability for predicting the outcome post-LT to the other four prognostic models(chronic liver failure-consortium ACLF score,Chinese Group on the Study of Severe Hepatitis B-ACLF score,model for end-stage liver disease score and Child-Turcotte-Pugh score).Conclusions:The presence of cirrhosis-related complications pre-LT increases the risk of death post-LT in patients with ACLF.The TACC model based on the number of cirrhosis-related complications pre-LT could stratify posttransplant survival,which might help to determine transplant timing for ACLF.