High-energy-density fuels are important for volume-limited aerospace vehicles,but the increase in fuel energy density always leads to poor cryogenic performance.Herein,we investigated the transposed Paternò-B...High-energy-density fuels are important for volume-limited aerospace vehicles,but the increase in fuel energy density always leads to poor cryogenic performance.Herein,we investigated the transposed Paternò-Büchi reaction of biomass cyclic ketone and cyclic alkene to synthesize a new kind of alkyl-substituted polycyclic hydrocarbon fuel with high energy density and good cryogenic performance.The triplet-energy-quenching results and phosphorescent emission spectra reveal the sensitization mechanism of the reaction,including photosensitizer excitation,triplettriplet energy transfer,cyclization,and relaxation,and the possible reaction path was revealed by the density functional theory(DFT)calculations.The reaction conditions of photosensitizer type and addition,molar ratio of substrates,reaction temperature,and incident light intensity were optimized,with the target product yield achieving 65.5%.Moreover,the reaction dynamics of the reaction rate versus the light intensity are established.After the hydrogenation-deoxygenation reaction,three fuels with a high density of 0.864-0.938 g·ml^(-1) and a low freezing point of<-55℃ are obtained.This work provides a benign and effective approach to synthesize high-performance fuels.展开更多
This paper is devoted to the study of a translation plane π(C) associated with a t-spread set C and its transposed t-spread set C t. In this paper, an explicit matrix form of the inverse of an isomorphism from a tran...This paper is devoted to the study of a translation plane π(C) associated with a t-spread set C and its transposed t-spread set C t. In this paper, an explicit matrix form of the inverse of an isomorphism from a translation plane into another translation plane associated with t-spread sets is derived and proved that two translation planes associated with t-spread sets are isomorphic if and only if their corresponding transposed translation planes are isomorphic. Further, it is shown that the transpose of a flag-transitive plane is flag-transitive and derived a necessary and sufficient condition for a translation plane π(C) to be isomorphic to its transposed translation plane.展开更多
It is known that if A∈Mn is normal (AA*=A*A) , then AA ̄=A ̄A if and only if AAT=ATA. This leads to the question: do both AA ̄=A ̄A and AAT=ATA?imply that A?is normal? We give an example to show that this is false wh...It is known that if A∈Mn is normal (AA*=A*A) , then AA ̄=A ̄A if and only if AAT=ATA. This leads to the question: do both AA ̄=A ̄A and AAT=ATA?imply that A?is normal? We give an example to show that this is false when n=4, but we show that it is true when n=2?and n=3.展开更多
Gradient-based iterative algorithm is suggested for solving a coupled complex conjugate and transpose matrix equations. Using the hierarchical identification principle and the real representation of a complex matrix, ...Gradient-based iterative algorithm is suggested for solving a coupled complex conjugate and transpose matrix equations. Using the hierarchical identification principle and the real representation of a complex matrix, a convergence proof is offered. The necessary and sufficient conditions for the optimal convergence factor are determined. A numerical example is offered to validate the efficacy of the suggested algorithm.展开更多
In this paper, an improved Fast-R-CNN nuclear power cold source disaster biological image recognition algorithm is proposed to improve the safety operation of nuclear power plants. Firstly, the image data sets of the ...In this paper, an improved Fast-R-CNN nuclear power cold source disaster biological image recognition algorithm is proposed to improve the safety operation of nuclear power plants. Firstly, the image data sets of the disaster-causing creatures hairy shrimp and jellyfish were established. Then, in order to solve the problems of low recognition accuracy and unrecognizable small entities in disaster biometrics, Gamma correction algorithm was used to optimize the image of the data set, improve the image quality and reduce the noise interference. Transposed convolution is introduced into the convolution layer to increase the recognition accuracy of small targets. The experimental results show that the recognition rate of this algorithm is 6.75%, 7.5%, 9.8% and 9.03% higher than that of ResNet-50, MobileNetv1, GoogleNet and VGG16, respectively. The actual test results show that the accuracy of this algorithm is obviously better than other algorithms, and the recognition efficiency is higher, which basically meets the preset requirements of this paper.展开更多
The process of turning forest area into land is known as deforestation or forest degradation. Reforestation as a fraction of deforestation is extremely low. For improved qualitative and quantitative classification, we...The process of turning forest area into land is known as deforestation or forest degradation. Reforestation as a fraction of deforestation is extremely low. For improved qualitative and quantitative classification, we used Sentinel-1 dataset of State of Para, Brazil to precisely and closely monitor deforestation between June 2019 and June 2023. This research aimed to find out suitable model for classification called Satellite Imaging analysis by Transpose deep neural transformation network (SIT-net) using mathematical model based on Band math approach to classify deforestation applying transpose deep neural network. The main advantage of proposed model is easy to handle SAR images. The study concludes that SAR satellite gives high-resolution images to improve deforestation monitoring and proposed model takes less computational time compared to other techniques.展开更多
Regulatory sequences and transposable elements(TEs)account for a large proportion of the genomic sequences of species;however,their roles in gene transcription,especially tissue-specific expression,remain largely unkn...Regulatory sequences and transposable elements(TEs)account for a large proportion of the genomic sequences of species;however,their roles in gene transcription,especially tissue-specific expression,remain largely unknown.Pigs serve as an excellent animal model for studying genomic sequence biology due to the extensive diversity among their wild and domesticated populations.Here,we conducted an integrated analysis using H3K27ac ChIP-seq,H3K4me3 ChIP-seq,and RNA-seq data from 10 different tissues of seven fetuses and eight closely related adult pigs.We aimed to annotate the regulatory elements and TEs to elucidate their associations with histone modifications and mRNA expression across different tissues and developmental stages.Based on correlation analysis between mRNA expression and H3K27ac and H3K4me3 peak activity,results indicated that H3K27ac exhibited stronger associations with gene expression than H3K4me3.Furthermore,1.45%of TEs overlapped with either the H3K27ac or H3K4me3 peaks,with the majority displaying tissue-specific activity.Notably,a TE subfamily(LTR4C_SS),containing binding motifs for SIX1 and SIX4,showed specific enrichment in the H3K27ac peaks of the adult and fetal ovaries.RNA-seq analysis also revealed widespread expression of TEs in the exons or promoters of genes,including 4688 TE-containing transcripts with distinct development stage-specific and tissue-specific expression.Of note,1967 TE-containing transcripts were enriched in the testes.We identified a long terminal repeat(LTR),MLT1F1,acting as a testis-specific alternative promoter in SRPK2(a cell cycle-related protein kinase)in our pig dataset.This element was also conserved in humans and mice,suggesting either an ancient integration of TEs in genes specifically expressed in the testes or parallel evolutionary patterns.Collectively,our findings demonstrate that TEs are deeply embedded in the genome and exhibit important tissue-specific biological functions,particularly in the reproductive organs.展开更多
A compact High Temperature Superconductor(HTS)cable that can carry large current is crucial for developing high field superconducting accelerator magnets.Herein,we are reporting a high current and low AC loss REBCO ca...A compact High Temperature Superconductor(HTS)cable that can carry large current is crucial for developing high field superconducting accelerator magnets.Herein,we are reporting a high current and low AC loss REBCO cable that adopts the Roebel structure,but it is implemented by in‐plane bending stacked REBCO tapes directly to realize the transposition,instead of by punching REBCO tapes to the desired shape.The cable maximizes the utilization of the original REBCO tapes,so that the material cost is significantly reduced comparing with the present“Roebel”REBCO cable.Recently,a prototype cable has been successfully fabricated.The critical current of each REBCO tape after cabling shows no degradation,and the cable’s measured critical current is 1939.8 A at 77 K and self‐field,which is very close to the predicted critical current by simulation.Calculations also show that the AC loss of the cable is lower compared with that of a simple REBCO stack with the same cross‐section and current‐carrying capacity.In this paper,we first introduce the fabrication process of the cable.What follows is the measurement of the in‐plane bending performance of REBCO tapes.Then,we present the design and fabrication of the prototype cable together with current‐carrying performance tests.Finally,the AC loss calculation and analysis of the cable are reported.展开更多
Although accurate coding of letter or character identities and positions is very important for word recognition,it is well established that transposed-letter(TL)words or transposedcharacter(TC)words do not influence w...Although accurate coding of letter or character identities and positions is very important for word recognition,it is well established that transposed-letter(TL)words or transposedcharacter(TC)words do not influence word processing.However,most previous studies mainly examined TL words presented horizontally from left to right and considered less whether the same effect would occur with unusual text orientations.This paper examines the issue of whether unfamiliar text orientations would affect TL word processing when words are presented vertically from top to bottom or bottom to top,horizontally from right to left,or extremely rotated by 90°or 180°.Moreover,this paper also looks at the issue of whether readers’previous language backgrounds(monolingual vs.bilingual)and language-specific text orientations(single reading direction vs.multiple text orientations)influence TL word processing in unfamiliar circumstances.Based on the most recent evidence,this paper is in favor of the abstract letter units account which proposes that the basis of orthographic coding in skilled readers is abstract representations.Furthermore,a reconsideration from a perspective of Saussure’s conceptions of the signified and the signifier is developed.In the end,two main directions of future research are suggested:first,to the realm of bilingual TL study,with the aim to specify the key reasons why bilinguals demonstrate mixed results under unfamiliar text orientations and second,to the realm of sentence reading,in order to specify how orthographic information can be processed across longer text units other than words.展开更多
The fine-tuned expression dynamics of the effector genes are pivotal for the transition from vegetative growth to host colonization of pathogenic filamentous fungi.However,mechanisms underlying the dynamic regulation ...The fine-tuned expression dynamics of the effector genes are pivotal for the transition from vegetative growth to host colonization of pathogenic filamentous fungi.However,mechanisms underlying the dynamic regulation of these genes remain largely unknown.Here,through comparative transcriptome and chromatin immunoprecipitation sequencing(ChIP-seq)analyses of the methyltransferase PoKmt6 in rice blast fungus Pyricularia oryzae(syn.Magnaporthe oryzae),we found that PoKmt6-mediated H3K27me3 deposition was enriched mainly at fast-evolving regions and contributed to the silencing of a subset of secreted proteins(SP)and transposable element(TE)families during the vegetative growth of P.oryzae.Intriguingly,we observed that a group of SP genes,which were depleted of H3K27me3 modification,could also be silenced via the H3K27me3-mediated repression of the nearby TEs.In conclusion,our results indicate that H3K27me3 modification mediated by PoKmt6 regulates the expression of some SP genes in fast-evolving regions through the suppression of nearby TEs.展开更多
Background:A comprehensive landscape of chromatin states for multiple mammalian tissues is essential for elucidating the molecular mechanism underlying regulatory variants on complex traits.However,the genome-wide chr...Background:A comprehensive landscape of chromatin states for multiple mammalian tissues is essential for elucidating the molecular mechanism underlying regulatory variants on complex traits.However,the genome-wide chromatin accessibility has been only reported in limited tissue types in pigs.Results:Here we report a genome-wide landscape of chromatin accessibility of 20 tissues in two female pigs at ages of 6 months using ATAC-seq,and identified 557,273 merged peaks,which greatly expanded the pig regulatory ele-ment repository.We revealed tissue-specific regulatory elements which were associated with tissue-relevant biologi-cal functions.We identified both positive and negative significant correlations between the regulatory elements and gene transcripts,which showed distinct distributions in terms of their strength and distances from corresponding genes.We investigated the presence of transposable elements(TEs)in open chromatin regions across all tissues,these included identifications of porcine endogenous retroviruses(PERVs)exhibiting high accessibility in liver and homology of porcine specific virus sequences to universally accessible transposable elements.Furthermore,we prior-itized a potential causal variant for polyunsaturated fatty acid in the muscle.Conclusions:Our data provides a novel multi-tissues accessible chromatin landscape that serve as an important resource for interpreting regulatory sequences in tissue-specific and conserved biological functions,as well as regula-tory variants of loci associated with complex traits in pigs.展开更多
A twin ovary mutant derived from the doubled haploid (DH) progeny of a cross,02428/Gui 630, was presumably related to the transposition of some transposable elements. Up to date, all reported the active transposable ...A twin ovary mutant derived from the doubled haploid (DH) progeny of a cross,02428/Gui 630, was presumably related to the transposition of some transposable elements. Up to date, all reported the active transposable elements in rice (Oryza sativa L.) are copia like retrotransposons. In the present study, the reverse transcriptase domains of copia like retrotransposons were amplified from the total DNA isolated from the mutant plants with the degenerated oligonucleotide primers for the domain. Three cloned insert DNAs, R33 1, R33 4 and R33 8, representing putative different copia like retrotransposons were screened out. Two of them displayed high polymorphism between “Zhaiyeqing 8” and “Jingxi 17”. Nine of the polymorphic bands were mapped on seven rice chromosomes. Sequencing analysis revealed that stop codons frequently occur in the sequence of R33 8, while both R33 1 and R33 4 contain a continuous coding region for 81 putative amino acid residues. No significant variation in hybridization patterns was found between indica and japonica rice or among 26 varieties of indica rice when R33 1 was used as a probe. Nevertheless, when R33 4 was used as a probe, high polymorphisms were detected both between indica and japonica rice and among 26 indica varieties, implying that this element might still be active in rice genomes.展开更多
AIM: To investigate the electric and contractile mechanisms involved in the deranged function of the transposed stomach in relation to the course of the symptoms and the changes in contractile and electrical parameter...AIM: To investigate the electric and contractile mechanisms involved in the deranged function of the transposed stomach in relation to the course of the symptoms and the changes in contractile and electrical parameters over time.METHODS: Twenty-one patients after subtotal esophagectomy and 18 healthy volunteers were studied.Complaints were compiled by using a questionnaire, and a symptom score was formed. Synchronous electrogastrography and gastric manometry were performed in the fasting state and postprandially.RESULTS: Eight of the operated patients were symptomfree and 13 had symptoms. The durations of the postoperative periods for the symptomatic (9.1±6.5 mo)and the asymptomatic (28.3±8.8 mo) patients were significantly different. The symptom score correlated negatively with the time that had elapsed since the operation. The percentages of the dominant frequency in the normogastric, bradygastric and tachygastric ranges differed significantly between the controls and the patients.A significant difference was detected between the power ratio of the controls and that of the patients. The occurrence of tachygastria in the symptomatic and the symptom-free patients correlated negatively both with the time that had elapsed and with the symptom score. There was a significant increase in motility index after feeding in the controls, but not in the patients. The contractile activity of the stomach increased both in the controls and in the symptom-free patients. In contrast, in the group of symptomatic patients, the contractile activity decreased postprandially as compared with the fasting state.CONCLUSION: The patients' post-operative complaints and symptoms change during the post-operative period and correlate with the parameters of the myoelectric and contractile activities of the stomach. Tachygastria seems to be the major pathogenetic factor involved in the contractile dysfunction.展开更多
AIM:To analyze the clinical efficacy of the partial rectus muscle transportation(PRT)procedure for paralytic strabismus due to single rectus muscle palsy.METHODS:In total,28 patients(31 eyes)who underwent the PRT proc...AIM:To analyze the clinical efficacy of the partial rectus muscle transportation(PRT)procedure for paralytic strabismus due to single rectus muscle palsy.METHODS:In total,28 patients(31 eyes)who underwent the PRT procedure for paralytic strabismus due to single rectus muscle palsy were retrospectively examined.The following data were collected pre-and postoperatively:angle of deviation in the primary position,presence of diplopia in the primary position,presence of compensatory head posture,and motility of the affected eye.The follow-up period was 6 mo.RESULTS:Based on the preoperative and intraoperative findings,different operations were performed:2 eyes were treated with PRT,26 eyes were treated with PRT combined with the recession of the antagonist muscle(Am)of the paralytic rectus muscle,and 3 eyes were treated with PRT along with the recession of the Am and the yoke muscle(Ym).On the first day after the operation,24 patients were found to be orthophoric in the primary position,without diplopia or abnormal head posture.Moreover,2 patients with monocular lateral rectus muscle palsy had mild overcorrection to 5 prism diopters(PD)and 8 PD,respectively,whereas 2 patients with binocular lateral rectus muscle palsy had mild undercorrection to 8 PD and 10 PD,respectively.During the 6-month follow-up period,the mean deviation was rectified from 96.79±41.21 PD to 0.64±2.38 PD(t=12.48,P<0.001),whereas the deviations in the 2 patients with mild overcorrection were corrected to orthotropia.The mean preoperative limitation of motility improved from-4.55±0.51 to-2.65±0.61(t=-15.13,P<0.001)after 6 mo postoperatively.CONCLUSION:PRT is an effective treatment for complete paralytic strabismus due to single rectus muscle palsy,and can achieve stable clinical efficacy.展开更多
We construct bound entangled states that are entangled but from which no entanglement can De olstilled It all parues are allowed only by performing local operations and classical communications. Moreover, as applicati...We construct bound entangled states that are entangled but from which no entanglement can De olstilled It all parues are allowed only by performing local operations and classical communications. Moreover, as applications, a detailed example is presented. This example can illuminate that the fidelity of transmission using a bound entangled state is not bigger than a classical scheme.展开更多
Marker free is a rapidly developed strategy that offers a new approach for the elimination of public concerns caused by the selectable marker genes conferring antibiotic or herbicide resistance and so on. Furthermore,...Marker free is a rapidly developed strategy that offers a new approach for the elimination of public concerns caused by the selectable marker genes conferring antibiotic or herbicide resistance and so on. Furthermore, marker_free transgenic plants (MFTPs) have a number of special advantages, such as decreasing the concerns about safety of selectable marker and stacking transgenes progressively into transgenic plants, which significantly owns potential application value. Major approaches developed recently for obtaining MFTPs were reviewed in this paper.展开更多
In order to overcome the shortcomings of the previous obstacle avoidance algorithms,an obstacle avoidance algorithm applicable to multiple mobile obstacles was proposed.The minimum prediction distance between obstacle...In order to overcome the shortcomings of the previous obstacle avoidance algorithms,an obstacle avoidance algorithm applicable to multiple mobile obstacles was proposed.The minimum prediction distance between obstacles and a manipulator was obtained according to the states of obstacles and transformed to escape velocity of the corresponding link of the manipulator.The escape velocity was introduced to the gradient projection method to obtain the joint velocity of the manipulator so as to complete the obstacle avoidance trajectory planning.A7-DOF manipulator was used in the simulation,and the results verified the effectiveness of the algorithm.展开更多
Transposable elements are capable of switching their positions on the genome thereby causing gene arrangements and contributing to genome evolution. The aim of this review is to specifically discuss the role of transp...Transposable elements are capable of switching their positions on the genome thereby causing gene arrangements and contributing to genome evolution. The aim of this review is to specifically discuss the role of transposable elements in transferring antimicrobial resistance genes in E. coli, thus contributing to increase in virulence and conferring the possibility of multidrug resistance. Different types of transposable elements such as transposons and integrons and their profound influence on E. coli antimicrobial resistance are the focus of this review.展开更多
基金support from National Key Research and Development Program of China(2021YFC2103704)the National Natural Science Foundation of China(22222808,21978200)the Haihe Laboratory of Sustainable Chemical Transformations.
文摘High-energy-density fuels are important for volume-limited aerospace vehicles,but the increase in fuel energy density always leads to poor cryogenic performance.Herein,we investigated the transposed Paternò-Büchi reaction of biomass cyclic ketone and cyclic alkene to synthesize a new kind of alkyl-substituted polycyclic hydrocarbon fuel with high energy density and good cryogenic performance.The triplet-energy-quenching results and phosphorescent emission spectra reveal the sensitization mechanism of the reaction,including photosensitizer excitation,triplettriplet energy transfer,cyclization,and relaxation,and the possible reaction path was revealed by the density functional theory(DFT)calculations.The reaction conditions of photosensitizer type and addition,molar ratio of substrates,reaction temperature,and incident light intensity were optimized,with the target product yield achieving 65.5%.Moreover,the reaction dynamics of the reaction rate versus the light intensity are established.After the hydrogenation-deoxygenation reaction,three fuels with a high density of 0.864-0.938 g·ml^(-1) and a low freezing point of<-55℃ are obtained.This work provides a benign and effective approach to synthesize high-performance fuels.
文摘This paper is devoted to the study of a translation plane π(C) associated with a t-spread set C and its transposed t-spread set C t. In this paper, an explicit matrix form of the inverse of an isomorphism from a translation plane into another translation plane associated with t-spread sets is derived and proved that two translation planes associated with t-spread sets are isomorphic if and only if their corresponding transposed translation planes are isomorphic. Further, it is shown that the transpose of a flag-transitive plane is flag-transitive and derived a necessary and sufficient condition for a translation plane π(C) to be isomorphic to its transposed translation plane.
文摘It is known that if A∈Mn is normal (AA*=A*A) , then AA ̄=A ̄A if and only if AAT=ATA. This leads to the question: do both AA ̄=A ̄A and AAT=ATA?imply that A?is normal? We give an example to show that this is false when n=4, but we show that it is true when n=2?and n=3.
文摘Gradient-based iterative algorithm is suggested for solving a coupled complex conjugate and transpose matrix equations. Using the hierarchical identification principle and the real representation of a complex matrix, a convergence proof is offered. The necessary and sufficient conditions for the optimal convergence factor are determined. A numerical example is offered to validate the efficacy of the suggested algorithm.
文摘In this paper, an improved Fast-R-CNN nuclear power cold source disaster biological image recognition algorithm is proposed to improve the safety operation of nuclear power plants. Firstly, the image data sets of the disaster-causing creatures hairy shrimp and jellyfish were established. Then, in order to solve the problems of low recognition accuracy and unrecognizable small entities in disaster biometrics, Gamma correction algorithm was used to optimize the image of the data set, improve the image quality and reduce the noise interference. Transposed convolution is introduced into the convolution layer to increase the recognition accuracy of small targets. The experimental results show that the recognition rate of this algorithm is 6.75%, 7.5%, 9.8% and 9.03% higher than that of ResNet-50, MobileNetv1, GoogleNet and VGG16, respectively. The actual test results show that the accuracy of this algorithm is obviously better than other algorithms, and the recognition efficiency is higher, which basically meets the preset requirements of this paper.
文摘The process of turning forest area into land is known as deforestation or forest degradation. Reforestation as a fraction of deforestation is extremely low. For improved qualitative and quantitative classification, we used Sentinel-1 dataset of State of Para, Brazil to precisely and closely monitor deforestation between June 2019 and June 2023. This research aimed to find out suitable model for classification called Satellite Imaging analysis by Transpose deep neural transformation network (SIT-net) using mathematical model based on Band math approach to classify deforestation applying transpose deep neural network. The main advantage of proposed model is easy to handle SAR images. The study concludes that SAR satellite gives high-resolution images to improve deforestation monitoring and proposed model takes less computational time compared to other techniques.
基金supported by the National Natural Science Foundation of China(32160781)。
文摘Regulatory sequences and transposable elements(TEs)account for a large proportion of the genomic sequences of species;however,their roles in gene transcription,especially tissue-specific expression,remain largely unknown.Pigs serve as an excellent animal model for studying genomic sequence biology due to the extensive diversity among their wild and domesticated populations.Here,we conducted an integrated analysis using H3K27ac ChIP-seq,H3K4me3 ChIP-seq,and RNA-seq data from 10 different tissues of seven fetuses and eight closely related adult pigs.We aimed to annotate the regulatory elements and TEs to elucidate their associations with histone modifications and mRNA expression across different tissues and developmental stages.Based on correlation analysis between mRNA expression and H3K27ac and H3K4me3 peak activity,results indicated that H3K27ac exhibited stronger associations with gene expression than H3K4me3.Furthermore,1.45%of TEs overlapped with either the H3K27ac or H3K4me3 peaks,with the majority displaying tissue-specific activity.Notably,a TE subfamily(LTR4C_SS),containing binding motifs for SIX1 and SIX4,showed specific enrichment in the H3K27ac peaks of the adult and fetal ovaries.RNA-seq analysis also revealed widespread expression of TEs in the exons or promoters of genes,including 4688 TE-containing transcripts with distinct development stage-specific and tissue-specific expression.Of note,1967 TE-containing transcripts were enriched in the testes.We identified a long terminal repeat(LTR),MLT1F1,acting as a testis-specific alternative promoter in SRPK2(a cell cycle-related protein kinase)in our pig dataset.This element was also conserved in humans and mice,suggesting either an ancient integration of TEs in genes specifically expressed in the testes or parallel evolutionary patterns.Collectively,our findings demonstrate that TEs are deeply embedded in the genome and exhibit important tissue-specific biological functions,particularly in the reproductive organs.
基金supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDB25000000)the National Key R&D Program of China(Grant No.2018YFA0704200)the Jialin Xie fund(Grant No.E2546KU2)。
文摘A compact High Temperature Superconductor(HTS)cable that can carry large current is crucial for developing high field superconducting accelerator magnets.Herein,we are reporting a high current and low AC loss REBCO cable that adopts the Roebel structure,but it is implemented by in‐plane bending stacked REBCO tapes directly to realize the transposition,instead of by punching REBCO tapes to the desired shape.The cable maximizes the utilization of the original REBCO tapes,so that the material cost is significantly reduced comparing with the present“Roebel”REBCO cable.Recently,a prototype cable has been successfully fabricated.The critical current of each REBCO tape after cabling shows no degradation,and the cable’s measured critical current is 1939.8 A at 77 K and self‐field,which is very close to the predicted critical current by simulation.Calculations also show that the AC loss of the cable is lower compared with that of a simple REBCO stack with the same cross‐section and current‐carrying capacity.In this paper,we first introduce the fabrication process of the cable.What follows is the measurement of the in‐plane bending performance of REBCO tapes.Then,we present the design and fabrication of the prototype cable together with current‐carrying performance tests.Finally,the AC loss calculation and analysis of the cable are reported.
文摘Although accurate coding of letter or character identities and positions is very important for word recognition,it is well established that transposed-letter(TL)words or transposedcharacter(TC)words do not influence word processing.However,most previous studies mainly examined TL words presented horizontally from left to right and considered less whether the same effect would occur with unusual text orientations.This paper examines the issue of whether unfamiliar text orientations would affect TL word processing when words are presented vertically from top to bottom or bottom to top,horizontally from right to left,or extremely rotated by 90°or 180°.Moreover,this paper also looks at the issue of whether readers’previous language backgrounds(monolingual vs.bilingual)and language-specific text orientations(single reading direction vs.multiple text orientations)influence TL word processing in unfamiliar circumstances.Based on the most recent evidence,this paper is in favor of the abstract letter units account which proposes that the basis of orthographic coding in skilled readers is abstract representations.Furthermore,a reconsideration from a perspective of Saussure’s conceptions of the signified and the signifier is developed.In the end,two main directions of future research are suggested:first,to the realm of bilingual TL study,with the aim to specify the key reasons why bilinguals demonstrate mixed results under unfamiliar text orientations and second,to the realm of sentence reading,in order to specify how orthographic information can be processed across longer text units other than words.
基金the grants from the National Natural Science Foundation of China(U1805232,31770156,and 32172365)the China Postdoctoral Science Foundation(2021M690637)。
文摘The fine-tuned expression dynamics of the effector genes are pivotal for the transition from vegetative growth to host colonization of pathogenic filamentous fungi.However,mechanisms underlying the dynamic regulation of these genes remain largely unknown.Here,through comparative transcriptome and chromatin immunoprecipitation sequencing(ChIP-seq)analyses of the methyltransferase PoKmt6 in rice blast fungus Pyricularia oryzae(syn.Magnaporthe oryzae),we found that PoKmt6-mediated H3K27me3 deposition was enriched mainly at fast-evolving regions and contributed to the silencing of a subset of secreted proteins(SP)and transposable element(TE)families during the vegetative growth of P.oryzae.Intriguingly,we observed that a group of SP genes,which were depleted of H3K27me3 modification,could also be silenced via the H3K27me3-mediated repression of the nearby TEs.In conclusion,our results indicate that H3K27me3 modification mediated by PoKmt6 regulates the expression of some SP genes in fast-evolving regions through the suppression of nearby TEs.
基金supported by National Key Research and Development Program of China(2021YFF1000601).
文摘Background:A comprehensive landscape of chromatin states for multiple mammalian tissues is essential for elucidating the molecular mechanism underlying regulatory variants on complex traits.However,the genome-wide chromatin accessibility has been only reported in limited tissue types in pigs.Results:Here we report a genome-wide landscape of chromatin accessibility of 20 tissues in two female pigs at ages of 6 months using ATAC-seq,and identified 557,273 merged peaks,which greatly expanded the pig regulatory ele-ment repository.We revealed tissue-specific regulatory elements which were associated with tissue-relevant biologi-cal functions.We identified both positive and negative significant correlations between the regulatory elements and gene transcripts,which showed distinct distributions in terms of their strength and distances from corresponding genes.We investigated the presence of transposable elements(TEs)in open chromatin regions across all tissues,these included identifications of porcine endogenous retroviruses(PERVs)exhibiting high accessibility in liver and homology of porcine specific virus sequences to universally accessible transposable elements.Furthermore,we prior-itized a potential causal variant for polyunsaturated fatty acid in the muscle.Conclusions:Our data provides a novel multi-tissues accessible chromatin landscape that serve as an important resource for interpreting regulatory sequences in tissue-specific and conserved biological functions,as well as regula-tory variants of loci associated with complex traits in pigs.
文摘A twin ovary mutant derived from the doubled haploid (DH) progeny of a cross,02428/Gui 630, was presumably related to the transposition of some transposable elements. Up to date, all reported the active transposable elements in rice (Oryza sativa L.) are copia like retrotransposons. In the present study, the reverse transcriptase domains of copia like retrotransposons were amplified from the total DNA isolated from the mutant plants with the degenerated oligonucleotide primers for the domain. Three cloned insert DNAs, R33 1, R33 4 and R33 8, representing putative different copia like retrotransposons were screened out. Two of them displayed high polymorphism between “Zhaiyeqing 8” and “Jingxi 17”. Nine of the polymorphic bands were mapped on seven rice chromosomes. Sequencing analysis revealed that stop codons frequently occur in the sequence of R33 8, while both R33 1 and R33 4 contain a continuous coding region for 81 putative amino acid residues. No significant variation in hybridization patterns was found between indica and japonica rice or among 26 varieties of indica rice when R33 1 was used as a probe. Nevertheless, when R33 4 was used as a probe, high polymorphisms were detected both between indica and japonica rice and among 26 indica varieties, implying that this element might still be active in rice genomes.
文摘AIM: To investigate the electric and contractile mechanisms involved in the deranged function of the transposed stomach in relation to the course of the symptoms and the changes in contractile and electrical parameters over time.METHODS: Twenty-one patients after subtotal esophagectomy and 18 healthy volunteers were studied.Complaints were compiled by using a questionnaire, and a symptom score was formed. Synchronous electrogastrography and gastric manometry were performed in the fasting state and postprandially.RESULTS: Eight of the operated patients were symptomfree and 13 had symptoms. The durations of the postoperative periods for the symptomatic (9.1±6.5 mo)and the asymptomatic (28.3±8.8 mo) patients were significantly different. The symptom score correlated negatively with the time that had elapsed since the operation. The percentages of the dominant frequency in the normogastric, bradygastric and tachygastric ranges differed significantly between the controls and the patients.A significant difference was detected between the power ratio of the controls and that of the patients. The occurrence of tachygastria in the symptomatic and the symptom-free patients correlated negatively both with the time that had elapsed and with the symptom score. There was a significant increase in motility index after feeding in the controls, but not in the patients. The contractile activity of the stomach increased both in the controls and in the symptom-free patients. In contrast, in the group of symptomatic patients, the contractile activity decreased postprandially as compared with the fasting state.CONCLUSION: The patients' post-operative complaints and symptoms change during the post-operative period and correlate with the parameters of the myoelectric and contractile activities of the stomach. Tachygastria seems to be the major pathogenetic factor involved in the contractile dysfunction.
文摘AIM:To analyze the clinical efficacy of the partial rectus muscle transportation(PRT)procedure for paralytic strabismus due to single rectus muscle palsy.METHODS:In total,28 patients(31 eyes)who underwent the PRT procedure for paralytic strabismus due to single rectus muscle palsy were retrospectively examined.The following data were collected pre-and postoperatively:angle of deviation in the primary position,presence of diplopia in the primary position,presence of compensatory head posture,and motility of the affected eye.The follow-up period was 6 mo.RESULTS:Based on the preoperative and intraoperative findings,different operations were performed:2 eyes were treated with PRT,26 eyes were treated with PRT combined with the recession of the antagonist muscle(Am)of the paralytic rectus muscle,and 3 eyes were treated with PRT along with the recession of the Am and the yoke muscle(Ym).On the first day after the operation,24 patients were found to be orthophoric in the primary position,without diplopia or abnormal head posture.Moreover,2 patients with monocular lateral rectus muscle palsy had mild overcorrection to 5 prism diopters(PD)and 8 PD,respectively,whereas 2 patients with binocular lateral rectus muscle palsy had mild undercorrection to 8 PD and 10 PD,respectively.During the 6-month follow-up period,the mean deviation was rectified from 96.79±41.21 PD to 0.64±2.38 PD(t=12.48,P<0.001),whereas the deviations in the 2 patients with mild overcorrection were corrected to orthotropia.The mean preoperative limitation of motility improved from-4.55±0.51 to-2.65±0.61(t=-15.13,P<0.001)after 6 mo postoperatively.CONCLUSION:PRT is an effective treatment for complete paralytic strabismus due to single rectus muscle palsy,and can achieve stable clinical efficacy.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.11101017 and 11275131)Beijing Natural Science Foundation andScientific Research Key Program of Beijing Municipal Commission of Education(Grant No.KZ201210028032)
文摘We construct bound entangled states that are entangled but from which no entanglement can De olstilled It all parues are allowed only by performing local operations and classical communications. Moreover, as applications, a detailed example is presented. This example can illuminate that the fidelity of transmission using a bound entangled state is not bigger than a classical scheme.
文摘Marker free is a rapidly developed strategy that offers a new approach for the elimination of public concerns caused by the selectable marker genes conferring antibiotic or herbicide resistance and so on. Furthermore, marker_free transgenic plants (MFTPs) have a number of special advantages, such as decreasing the concerns about safety of selectable marker and stacking transgenes progressively into transgenic plants, which significantly owns potential application value. Major approaches developed recently for obtaining MFTPs were reviewed in this paper.
基金Supported by Ministeral Level Advanced Research Foundation(65822576)Beijing Municipal Education Commission(KM201310858004,KM201310858001)
文摘In order to overcome the shortcomings of the previous obstacle avoidance algorithms,an obstacle avoidance algorithm applicable to multiple mobile obstacles was proposed.The minimum prediction distance between obstacles and a manipulator was obtained according to the states of obstacles and transformed to escape velocity of the corresponding link of the manipulator.The escape velocity was introduced to the gradient projection method to obtain the joint velocity of the manipulator so as to complete the obstacle avoidance trajectory planning.A7-DOF manipulator was used in the simulation,and the results verified the effectiveness of the algorithm.
文摘Transposable elements are capable of switching their positions on the genome thereby causing gene arrangements and contributing to genome evolution. The aim of this review is to specifically discuss the role of transposable elements in transferring antimicrobial resistance genes in E. coli, thus contributing to increase in virulence and conferring the possibility of multidrug resistance. Different types of transposable elements such as transposons and integrons and their profound influence on E. coli antimicrobial resistance are the focus of this review.