Objectives:To compare the depth of thermal necrosis after use of bipolar resection and vaporization technique comparing intra-individually bipolar loop and bipolar button electrodes.Methods:Transurethral resection and...Objectives:To compare the depth of thermal necrosis after use of bipolar resection and vaporization technique comparing intra-individually bipolar loop and bipolar button electrodes.Methods:Transurethral resection and vaporization of the prostate was performed in 55 male patients(260 specimens in total).In a standardized procedure,a bipolar resection loop was used for resection,and a bipolar button electrode was used for vaporization.Both electrodes were applied in each patient,either in the left or in the right lateral lobe.The depth of necrotic zones in the resected or vaporized tissue of each patient was measured in a standardized way by light microscopy.Results:The mean depth with standard deviation of thermal injury caused by the loop electrode was 0.0495±0.0274 mm.The vaporization electrode caused a mean thermal depth with standard deviation of 0.0477±0.0276 mm.The mean difference of necrosis zone depths between the two types of electrodes(PlasmaButtoneresection loop)was 0.0018 mm(p=0.691).Conclusion:For the first time,we present directly measured values of the absolute necrosis zone depth after application of plasma in the transurethral treatment of benign prostatic hyperplasia.The measured values were lower than in all other transurethral procedures.Standardized procedures of measurement and evaluation allow a statistically significant statement that the low necrosis depth in bipolar procedures is independent of the applied electrodes.展开更多
目的研究经尿道前列腺钬激光剜除术(holmium laser enucleation of the prostate,HoLEP)与经尿道双极等离子前列腺剜除术(transurethral bipolar plasma kinetic enucleation and resection of the prostate,PKERP)治疗前列腺增生的疗...目的研究经尿道前列腺钬激光剜除术(holmium laser enucleation of the prostate,HoLEP)与经尿道双极等离子前列腺剜除术(transurethral bipolar plasma kinetic enucleation and resection of the prostate,PKERP)治疗前列腺增生的疗效差异。方法选取2020年8月至2022年8月聊城市第二人民医院泌尿外科收治的前列腺增生患者90例,随机分为HoLEP组(45例,HoLEP治疗)、PKERP组(45例,PKERP治疗),比较两组围术期指标,测量术前、术后血清炎性因子、疼痛介质水平及最大尿流率,评估患者术后疼痛情况,统计术后并发症。结果HoLEP组术中出血量、膀胱冲洗天数、住院天数、导尿管留置天数均显著少于PKERP组;术后1周HoLEP组最大尿流率高于PKERP组;术后1天HoLEP组血清白介素-2(interleukin-2,IL-2)、白介素-6(interleukin-6,IL-6)均显著低于PKERP组(P<0.05);术后1天HoLEP组血清前列腺素E2(prostaglandin E2,PGE2)、5-羟色胺(5-hydroxy tryptamine,5-HT)水平显著低于PKERP组(P<0.05);术后1天、2天、3天HoLEP组疼痛视觉模拟评分法(visual analogue scale,VAS)均显著低于PKERP组,差异均有统计学意义(P<0.05);HoLEP组并发症发生率显著低于PKERP组(P<0.05)。结论HoLEP治疗前列腺增生,可显著下调患者术后炎性因子及疼痛介质水平,减轻患者术后疼痛感,且具有创伤性小、并发症少的优点。展开更多
文摘Objectives:To compare the depth of thermal necrosis after use of bipolar resection and vaporization technique comparing intra-individually bipolar loop and bipolar button electrodes.Methods:Transurethral resection and vaporization of the prostate was performed in 55 male patients(260 specimens in total).In a standardized procedure,a bipolar resection loop was used for resection,and a bipolar button electrode was used for vaporization.Both electrodes were applied in each patient,either in the left or in the right lateral lobe.The depth of necrotic zones in the resected or vaporized tissue of each patient was measured in a standardized way by light microscopy.Results:The mean depth with standard deviation of thermal injury caused by the loop electrode was 0.0495±0.0274 mm.The vaporization electrode caused a mean thermal depth with standard deviation of 0.0477±0.0276 mm.The mean difference of necrosis zone depths between the two types of electrodes(PlasmaButtoneresection loop)was 0.0018 mm(p=0.691).Conclusion:For the first time,we present directly measured values of the absolute necrosis zone depth after application of plasma in the transurethral treatment of benign prostatic hyperplasia.The measured values were lower than in all other transurethral procedures.Standardized procedures of measurement and evaluation allow a statistically significant statement that the low necrosis depth in bipolar procedures is independent of the applied electrodes.
文摘目的研究经尿道前列腺钬激光剜除术(holmium laser enucleation of the prostate,HoLEP)与经尿道双极等离子前列腺剜除术(transurethral bipolar plasma kinetic enucleation and resection of the prostate,PKERP)治疗前列腺增生的疗效差异。方法选取2020年8月至2022年8月聊城市第二人民医院泌尿外科收治的前列腺增生患者90例,随机分为HoLEP组(45例,HoLEP治疗)、PKERP组(45例,PKERP治疗),比较两组围术期指标,测量术前、术后血清炎性因子、疼痛介质水平及最大尿流率,评估患者术后疼痛情况,统计术后并发症。结果HoLEP组术中出血量、膀胱冲洗天数、住院天数、导尿管留置天数均显著少于PKERP组;术后1周HoLEP组最大尿流率高于PKERP组;术后1天HoLEP组血清白介素-2(interleukin-2,IL-2)、白介素-6(interleukin-6,IL-6)均显著低于PKERP组(P<0.05);术后1天HoLEP组血清前列腺素E2(prostaglandin E2,PGE2)、5-羟色胺(5-hydroxy tryptamine,5-HT)水平显著低于PKERP组(P<0.05);术后1天、2天、3天HoLEP组疼痛视觉模拟评分法(visual analogue scale,VAS)均显著低于PKERP组,差异均有统计学意义(P<0.05);HoLEP组并发症发生率显著低于PKERP组(P<0.05)。结论HoLEP治疗前列腺增生,可显著下调患者术后炎性因子及疼痛介质水平,减轻患者术后疼痛感,且具有创伤性小、并发症少的优点。
