Although occupying pillar position in clinical cancer treatments,surgery itself and surgical trauma would elicit series of local/systemic inflammation-related responses that resulted in high rate of tumor recurrence.H...Although occupying pillar position in clinical cancer treatments,surgery itself and surgical trauma would elicit series of local/systemic inflammation-related responses that resulted in high rate of tumor recurrence.Herein,chitosan with conjugated gallic acid(CSG)molecules were coordinated with Fe3+to form CSG/Fe3+hydrogel for filling the tumo r-resected cavity with considerable wet-adhesion ability and anti-inflammatory performance.With the assistance of doxorubicin hydrochloride(DOX·HCl),CSG/Fe3+/DOX hydrogel exhibited syne rgistic photothermal-chemo tumo r-inhibited performance under near-infrared(NIR)light irradiation for eradicating residual and/or surgical trauma-recruited cancer cells.Thus,our study attempts to show a paradigm that realizes quick surgical trauma healing,inflammation inhibition and prevention of postsurgical tumor recurrence.展开更多
Celeste Ng’s first novel Everything I Never Told is about a tragedy that happened in a mixed race family,the family of a Chinese American college professor and his stay-at-home white wife in a small Ohio town in the ...Celeste Ng’s first novel Everything I Never Told is about a tragedy that happened in a mixed race family,the family of a Chinese American college professor and his stay-at-home white wife in a small Ohio town in the 1970s.The novel looks at the trau⁃matic events suffered by the Chinese American family,but facing the traumatic memory and reshaping the family relationship are the writing purposes of Celeste Ng.Based on trauma theory,the transmission of trauma in Chinese American families would be dis⁃cussed.This kind of trauma not only harms the parents'generation,but also affects the healthy growth of the children's generation.The aim of the novel is to find a way to recover from such traumatic transmission.展开更多
基金the National Natural Science Foundation of China(Nos.31800834,51572067)the University Synergy Innovation Program of Anhui Province(No.GXXT-2019-045)the Fundamental Research Funds for the Central Universities(Nos.JZ2018HGPA0273,JZ2018HGPA0269,JZ2018HGTB0247)。
文摘Although occupying pillar position in clinical cancer treatments,surgery itself and surgical trauma would elicit series of local/systemic inflammation-related responses that resulted in high rate of tumor recurrence.Herein,chitosan with conjugated gallic acid(CSG)molecules were coordinated with Fe3+to form CSG/Fe3+hydrogel for filling the tumo r-resected cavity with considerable wet-adhesion ability and anti-inflammatory performance.With the assistance of doxorubicin hydrochloride(DOX·HCl),CSG/Fe3+/DOX hydrogel exhibited syne rgistic photothermal-chemo tumo r-inhibited performance under near-infrared(NIR)light irradiation for eradicating residual and/or surgical trauma-recruited cancer cells.Thus,our study attempts to show a paradigm that realizes quick surgical trauma healing,inflammation inhibition and prevention of postsurgical tumor recurrence.
文摘Celeste Ng’s first novel Everything I Never Told is about a tragedy that happened in a mixed race family,the family of a Chinese American college professor and his stay-at-home white wife in a small Ohio town in the 1970s.The novel looks at the trau⁃matic events suffered by the Chinese American family,but facing the traumatic memory and reshaping the family relationship are the writing purposes of Celeste Ng.Based on trauma theory,the transmission of trauma in Chinese American families would be dis⁃cussed.This kind of trauma not only harms the parents'generation,but also affects the healthy growth of the children's generation.The aim of the novel is to find a way to recover from such traumatic transmission.
