期刊文献+
共找到4篇文章
< 1 >
每页显示 20 50 100
Recovery of corticospinal tract injured by traumatic axonal injury at the subcortical white matter:a case report
1
作者 Sung Ho Jang Seong Ho Kim Woo Hyuk Jang 《Neural Regeneration Research》 SCIE CAS CSCD 2016年第9期1527-1528,共2页
The corticospinal tract (CST) is a major neural tract for mo- tor function in the human brain. In addition, CST is mainly concerned with execution of movement of the hand (Jang, 2014). However, few studies are rep... The corticospinal tract (CST) is a major neural tract for mo- tor function in the human brain. In addition, CST is mainly concerned with execution of movement of the hand (Jang, 2014). However, few studies are reported on the mecha- nism underlying CST recovery after traumatic brain injury (Seo and Jang, 2015). In this study, we report on a case that showed recovery of an injured CST by traumatic axonal injury (TAI) at subcortical white matter, as detected on fol- low-up diffusion tensor tractography (DTT). 展开更多
关键词 Recovery of corticospinal tract injured by traumatic axonal injury at the subcortical white matter CST DTI case DTT than
下载PDF
Animal model of repetitive mild traumatic brain injury for human traumatic axonal injury and chronic traumatic encephalopathy
2
作者 Leyan Xu 《Neural Regeneration Research》 SCIE CAS CSCD 2015年第11期1731-1732,共2页
Chronic traumatic encephalopathy(CTE)is a chronic neurodegenerative disease featured with tauopathy.CTE is tightly related with repetitive mild traumatic brain injury(m TBI),which is interchangeably known as concu... Chronic traumatic encephalopathy(CTE)is a chronic neurodegenerative disease featured with tauopathy.CTE is tightly related with repetitive mild traumatic brain injury(m TBI),which is interchangeably known as concussion(Mc Kee et al.,2009,2013).This disease is differentiated by neuropathological features from other neurological diseases that involve tau protein aggregation and tangle formation abnormalities like Alzheimer's disease (AD), frontotemporal dementia, and Parkinson- ism linked to chromosome 17 (FTDP-17). 展开更多
关键词 TBI Animal model of repetitive mild traumatic brain injury for human traumatic axonal injury and chronic traumatic encephalopathy
下载PDF
A novel technique using hydrophilic polymers to promote axonal fusion 被引量:2
3
作者 Ravinder Bamba D.Colton Riley +3 位作者 Nathaniel D.Kelm Mark D.Does Richard D.Dortch Wesley P.Thayer 《Neural Regeneration Research》 SCIE CAS CSCD 2016年第4期525-528,共4页
The management of traumatic peripheral nerve injury remains a considerable concern for clinicians.With minimal innovations in surgical technique and a limited number of specialists trained to treat peripheral nerve in... The management of traumatic peripheral nerve injury remains a considerable concern for clinicians.With minimal innovations in surgical technique and a limited number of specialists trained to treat peripheral nerve injury,outcomes of surgical intervention have been unpredictable.The inability to manipulate the pathophysiology of nerve injury(i.e.,Wallerian degeneration) has left scientists and clinicians depending on the slow and lengthy process of axonal regeneration(-1 mm/day).When axons are severed,the endings undergo calcium-mediated plasmalemmal sealing,which limits the ability of the axon to be primarily repaired.Polythethylene glycol(PEG) in combination with a bioengineered process overcomes the inability to fuse axons.The mechanism for PEG axonal fusion is not clearly understood,but multiple studies have shown that a providing a calcium-free environment is essential to the process known as PEG fusion.The proposed mechanism is PEG-induced lipid bilayer fusion by removing the hydration barrier surrounding the axolemma and reducing the activation energy required for membrane fusion to occur.This review highlights PEG fusion,its past and current studies,and future directions in PEG fusion. 展开更多
关键词 peripheral nerve injury polyethylene glycol axonal fusion nerve transection traumatic neuropathy
下载PDF
Magnetic resonance imaging and cell-based neurorestorative therapy after brain injury 被引量:1
4
作者 Quan Jiang 《Neural Regeneration Research》 SCIE CAS CSCD 2016年第1期7-14,共8页
Restorative cell-based therapies for experimental brain injury, such as stroke and traumatic brain injury,substantially improve functional outcome. We discuss and review state of the art magnetic resonance imaging met... Restorative cell-based therapies for experimental brain injury, such as stroke and traumatic brain injury,substantially improve functional outcome. We discuss and review state of the art magnetic resonance imaging methodologies and their applications related to cell-based treatment after brain injury. We focus on the potential of magnetic resonance imaging technique and its associated challenges to obtain useful new information related to cell migration, distribution, and quantitation, as well as vascular and neuronal remodeling in response to cell-based therapy after brain injury. The noninvasive nature of imaging might more readily help with translation of cell-based therapy from the laboratory to the clinic. 展开更多
关键词 stroke traumatic brain injury traumatic brain injury MRI cell therapy cell labeling vascular remodeling axonal remodeling angiogenesis neuronal plasticity cerebral blood flow cerebral blood volume blood brain barrier permeability diffusion tensor MRI
下载PDF
上一页 1 下一页 到第
使用帮助 返回顶部