Background: Cervical cancer is a significant health concern in Bangladesh, with high mortality rates due to limited awareness and costly treatments. The disease stages influence treatment protocols, ranging from surge...Background: Cervical cancer is a significant health concern in Bangladesh, with high mortality rates due to limited awareness and costly treatments. The disease stages influence treatment protocols, ranging from surgery and radiotherapy for early stages to chemotherapy and radiation for advanced stages, but survival rates decrease as the cancer progresses. Objective: The objective of this study is to determine the economic impact of the disease and recommend cost-efficient strategies for prevention and treatment. Methods: A population-based, cross-sectional study was conducted with a stratified sample of cervical cancer patients from selected healthcare facilities across Bangladesh. Data collection involved structured interviews and validated questionnaires. The study measured the economic impact, treatment costs, and other related expenses. Quantitative data analysis was performed using SPSS v22, MS-Excel, and R Programming, with Multivariate regression analysis and Post Hoc tests, including the chi-square test, applied to selected indicators. Results: All respondents in the study were female, aged 34 - 75, with 72.3% aged 40 - 50. Most were illiterate (38.6%) and housewives (95.0%). Additionally, 98% were married, 85.10% married before age 18, and 46.50% experienced their first menstruation before age 12. Families typically had a monthly income of 10,000 - 30,000 Taka, spending similar amounts on treatment. Significant relationships were found between educational qualifications, occupation, personal hygiene practices, history of oral contraceptive use, and age of marriage (p Conclusion: The article emphasizes the impact of monthly family income on cervical cancer treatment costs, stressing the need for comprehensive support services to address the financial and emotional burdens faced by patients. Improving access to quality care and implementing measures can enhance outcomes for cervical cancer patients in Bangladesh.展开更多
AIM: To estimate the progression of the hepatitis C virus(HCV) epidemic and measure the burden of HCVrelated morbidity and mortality. METHODS: Age- and gender-defined cohorts were used to follow the viremic population...AIM: To estimate the progression of the hepatitis C virus(HCV) epidemic and measure the burden of HCVrelated morbidity and mortality. METHODS: Age- and gender-defined cohorts were used to follow the viremic population in Argentina and estimate HCV incidence, prevalence, hepatic complications, and mortality. The relative impact of two scenarios on HCV-related outcomes was assessed:(1) increased sustained virologic response(SVR); and(2) increased SVR and treatment.RESULTS: Under scenario 1, SVR raised to 85%-95% in 2016. Compared to the base case scenario, there was a 0.3% reduction in prevalent cases and liverrelated deaths by 2030. Given low treatment rates, cases of hepatocellular carcinoma and decompensated cirrhosis decreased < 1%, in contrast to the base case in 2030. Under scenario 2, the same increases in SVR were modeled, with gradual increases in the annual diagnosed and treated populations. This scenario decreased prevalent infections 45%, liver-related deaths 55%, liver cancer cases 60%, and decompensated cirrhosis 55%, as compared to the base case by 2030. CONCLUSION: In Argentina, cases of end stage liver disease and liver-related deaths due to HCV are still growing, while its prevalence is decreasing. Increasing in SVR rates is not enough, and increasing in the number of patients diagnosed and candidates for treatment is needed to reduce the HCV disease burden. Based on this scenario, strategies to increase diagnosis and treatment uptake must be developed to reduce HCV burden in Argentina.展开更多
Objective:To review the research status and progress of minimally disruptive medicine(MDM)with a view and to provide a theoretical basis for reducing the treatment burden of patients with multimorbidity.Methods:"...Objective:To review the research status and progress of minimally disruptive medicine(MDM)with a view and to provide a theoretical basis for reducing the treatment burden of patients with multimorbidity.Methods:"Minimal Destructive Medicine"was used as searching term in HowNet Database and Wanfang Database,and"Minimally Disruptive Medicine"was used as searching term in PubMed database.The literature was reviewed for a review of the concepts of minimally destructive medicine(MDM),four basic principles,care models,and tools and strategies for clinical implementation.Results:MDM was developed for the coexistence burden of chronic diseases.It had formed a detailed and detailed application of basic principles and care models.The tools and strategies developed by MDM have been applied in clinical practice with good Results.Conclusion:MDM has a positive effect on reducing the burden of treatment for the multimorbidity and it is worthy of further research and promotion.展开更多
目的分析并阐明慢病患者治疗负担的概念内涵。方法系统检索PubMed、Embase、Web of Science、Cochrane、中国知网、维普、万方、中国生物医学数据库中治疗负担的相关文献,检索时限为建库至2023年4月10日,采用Rodgers概念分析法进行分析...目的分析并阐明慢病患者治疗负担的概念内涵。方法系统检索PubMed、Embase、Web of Science、Cochrane、中国知网、维普、万方、中国生物医学数据库中治疗负担的相关文献,检索时限为建库至2023年4月10日,采用Rodgers概念分析法进行分析。结果共纳入47篇文献,慢病患者治疗负担包括动态的过程、多维度的概念、主客观负担3个概念属性;前因包括人口学因素、疾病与治疗因素、健康素养、心理因素、自我效能以及社会支持系统;后果包括依从性降低、生活质量下降、负性情绪、恶性循环、医疗资源利用不当等。常用测量工具包括治疗负担量表、患者治疗和自我管理体验量表、慢性病共存治疗负担问卷、老年慢病共存患者治疗负担量表。结论通过对慢性病患者治疗负担的概念分析,有助于提高医护人员认识,并为治疗负担在我国的进一步研究提供理论指导。展开更多
针对城市污水处理厂运行过程中产生微生物气溶胶,工作人员暴露于气溶胶环境可经呼吸摄入致病性微生物,最终造成健康寿命损失的问题,通过对污水处理厂空气中气溶胶颗粒及其携载的病原体进行定量识别,明确工作人员的职业暴露风险,进一步...针对城市污水处理厂运行过程中产生微生物气溶胶,工作人员暴露于气溶胶环境可经呼吸摄入致病性微生物,最终造成健康寿命损失的问题,通过对污水处理厂空气中气溶胶颗粒及其携载的病原体进行定量识别,明确工作人员的职业暴露风险,进一步结合微生物定量风险评估及疾病负担研究方法,以伤残寿命(disability adjusted life year, DALY)为健康评价指标,提出基于DALY的微生物气溶胶职业健康风险评估新模式及计算方法体系,并进一步遴选典型病原体进行疾病负担计算。结果表明:典型污水处理厂工作人员职业暴露过程中,经气溶胶摄入诺如病毒、腺病毒和轮状病毒造成的健康损失均明显高出WHO标准,需改进工艺或限制接触。展开更多
文摘Background: Cervical cancer is a significant health concern in Bangladesh, with high mortality rates due to limited awareness and costly treatments. The disease stages influence treatment protocols, ranging from surgery and radiotherapy for early stages to chemotherapy and radiation for advanced stages, but survival rates decrease as the cancer progresses. Objective: The objective of this study is to determine the economic impact of the disease and recommend cost-efficient strategies for prevention and treatment. Methods: A population-based, cross-sectional study was conducted with a stratified sample of cervical cancer patients from selected healthcare facilities across Bangladesh. Data collection involved structured interviews and validated questionnaires. The study measured the economic impact, treatment costs, and other related expenses. Quantitative data analysis was performed using SPSS v22, MS-Excel, and R Programming, with Multivariate regression analysis and Post Hoc tests, including the chi-square test, applied to selected indicators. Results: All respondents in the study were female, aged 34 - 75, with 72.3% aged 40 - 50. Most were illiterate (38.6%) and housewives (95.0%). Additionally, 98% were married, 85.10% married before age 18, and 46.50% experienced their first menstruation before age 12. Families typically had a monthly income of 10,000 - 30,000 Taka, spending similar amounts on treatment. Significant relationships were found between educational qualifications, occupation, personal hygiene practices, history of oral contraceptive use, and age of marriage (p Conclusion: The article emphasizes the impact of monthly family income on cervical cancer treatment costs, stressing the need for comprehensive support services to address the financial and emotional burdens faced by patients. Improving access to quality care and implementing measures can enhance outcomes for cervical cancer patients in Bangladesh.
文摘AIM: To estimate the progression of the hepatitis C virus(HCV) epidemic and measure the burden of HCVrelated morbidity and mortality. METHODS: Age- and gender-defined cohorts were used to follow the viremic population in Argentina and estimate HCV incidence, prevalence, hepatic complications, and mortality. The relative impact of two scenarios on HCV-related outcomes was assessed:(1) increased sustained virologic response(SVR); and(2) increased SVR and treatment.RESULTS: Under scenario 1, SVR raised to 85%-95% in 2016. Compared to the base case scenario, there was a 0.3% reduction in prevalent cases and liverrelated deaths by 2030. Given low treatment rates, cases of hepatocellular carcinoma and decompensated cirrhosis decreased < 1%, in contrast to the base case in 2030. Under scenario 2, the same increases in SVR were modeled, with gradual increases in the annual diagnosed and treated populations. This scenario decreased prevalent infections 45%, liver-related deaths 55%, liver cancer cases 60%, and decompensated cirrhosis 55%, as compared to the base case by 2030. CONCLUSION: In Argentina, cases of end stage liver disease and liver-related deaths due to HCV are still growing, while its prevalence is decreasing. Increasing in SVR rates is not enough, and increasing in the number of patients diagnosed and candidates for treatment is needed to reduce the HCV disease burden. Based on this scenario, strategies to increase diagnosis and treatment uptake must be developed to reduce HCV burden in Argentina.
文摘Objective:To review the research status and progress of minimally disruptive medicine(MDM)with a view and to provide a theoretical basis for reducing the treatment burden of patients with multimorbidity.Methods:"Minimal Destructive Medicine"was used as searching term in HowNet Database and Wanfang Database,and"Minimally Disruptive Medicine"was used as searching term in PubMed database.The literature was reviewed for a review of the concepts of minimally destructive medicine(MDM),four basic principles,care models,and tools and strategies for clinical implementation.Results:MDM was developed for the coexistence burden of chronic diseases.It had formed a detailed and detailed application of basic principles and care models.The tools and strategies developed by MDM have been applied in clinical practice with good Results.Conclusion:MDM has a positive effect on reducing the burden of treatment for the multimorbidity and it is worthy of further research and promotion.
文摘目的分析并阐明慢病患者治疗负担的概念内涵。方法系统检索PubMed、Embase、Web of Science、Cochrane、中国知网、维普、万方、中国生物医学数据库中治疗负担的相关文献,检索时限为建库至2023年4月10日,采用Rodgers概念分析法进行分析。结果共纳入47篇文献,慢病患者治疗负担包括动态的过程、多维度的概念、主客观负担3个概念属性;前因包括人口学因素、疾病与治疗因素、健康素养、心理因素、自我效能以及社会支持系统;后果包括依从性降低、生活质量下降、负性情绪、恶性循环、医疗资源利用不当等。常用测量工具包括治疗负担量表、患者治疗和自我管理体验量表、慢性病共存治疗负担问卷、老年慢病共存患者治疗负担量表。结论通过对慢性病患者治疗负担的概念分析,有助于提高医护人员认识,并为治疗负担在我国的进一步研究提供理论指导。
文摘针对城市污水处理厂运行过程中产生微生物气溶胶,工作人员暴露于气溶胶环境可经呼吸摄入致病性微生物,最终造成健康寿命损失的问题,通过对污水处理厂空气中气溶胶颗粒及其携载的病原体进行定量识别,明确工作人员的职业暴露风险,进一步结合微生物定量风险评估及疾病负担研究方法,以伤残寿命(disability adjusted life year, DALY)为健康评价指标,提出基于DALY的微生物气溶胶职业健康风险评估新模式及计算方法体系,并进一步遴选典型病原体进行疾病负担计算。结果表明:典型污水处理厂工作人员职业暴露过程中,经气溶胶摄入诺如病毒、腺病毒和轮状病毒造成的健康损失均明显高出WHO标准,需改进工艺或限制接触。
