A series of bis{oxo bis[heteroaromatic carboxylatodibenzyltin(Ⅳ)]} complexes {[(PhCH 2) 2Sn· (O 2CR)] 2O} 2[where R=2 furyl, 2 (2 furyl)vinyl, 2 (5 tert butyl)furyl, 2 thiophenyl, 2 pyridiny...A series of bis{oxo bis[heteroaromatic carboxylatodibenzyltin(Ⅳ)]} complexes {[(PhCH 2) 2Sn· (O 2CR)] 2O} 2[where R=2 furyl, 2 (2 furyl)vinyl, 2 (5 tert butyl)furyl, 2 thiophenyl, 2 pyridinyl, 3 pyridinyl , 4 pyridinyl, 3 indolyl, 3 indolylmethyl, 3 indolylpropyl] was synthesized by the reactions of heteroaromatic carboxylic acids with dibenzyltin(Ⅳ) oxide. All the complexes were characterized by elemental analysis, IR, and NMR spectra. The complexes were tested against two human tumour cell lines: MCF 7 and WiDr. The results show that they have higher activities in vitro . The crystal structure of bis{oxo bis[2 furylcarboxylatodibenzyltin(Ⅳ)]}(1) was determined by X ray diffraction. The crystal belongs to monoclinic space group P2 1/n, a =1 6641(2) nm, b =1 25073(18) nm, c =1 7193(3) nm, β= 101 951(2)° , Z=2, R 1=0 0446, wR 2=0 1100. Complex 1 is of a centrosymmetric dimer structure with a four membered central endo cyclic Sn 2O 2 unit in which the bridged oxygen atoms are tri coordinated. Each bridged oxygen atom also connects with an exo cyclic tin atom. The tin atoms are six coordinated and have a coordination geometry of a distorted octahedron. The exo cyclic tin atoms are five coordinated and have a coordination geometry of a monocapped trigonal bipyramid with a very similarly distorted mode. Four carboxylate ligands are divided into two types. The two of the four carboxylate ligands are bidentate and bridged to each pair of exo and endo cyclic tin atoms by using both the oxygen atoms. The other two are monodentate and bridged to each pair of exo and endo cyclic tin atoms but each utilizes one O atom only.展开更多
A coupled chemiluminescence method for the determination of some carhoxylic acids was devel-oped, based on their enhancement the chemiluminescence light emission of the reaction of tirs(2, 2'-bipyri-dine) rutheni...A coupled chemiluminescence method for the determination of some carhoxylic acids was devel-oped, based on their enhancement the chemiluminescence light emission of the reaction of tirs(2, 2'-bipyri-dine) ruthenium(Ⅱ) and Ce(Ⅳ) in sulfuric acid medium. The conditions for their determination were opti-mized. The following detection limits were obtained: oxalic acid, 2. 67×10-8 mol/L; propandioic acld, 1.20×10-6 mol/L; pyruvic acid, 1. 35 ×10-8 mol/L; citric acid, 5.10×10-8. mol/L; barbituric acid, 2.48×10-7,mol/L. The proposed method was successfully applied to determination or oxalic acid. The coupled chemilu-minescent reaction mechanism and rate equation are proposed.展开更多
The title ladder organotin carboxylate,{[（C6H5CH2）2Sn]4（p-NH2C6H4-COO）2O2（OCH3）2}·0.5H2O 1,has been synthesized and structurally characterized by elemental analyses,IR and single-crystal X-ray diffraction a...The title ladder organotin carboxylate,{[（C6H5CH2）2Sn]4（p-NH2C6H4-COO）2O2（OCH3）2}·0.5H2O 1,has been synthesized and structurally characterized by elemental analyses,IR and single-crystal X-ray diffraction analysis.Complex 1 is located across on an inversion center and displays a Sn4O4 ladder-like structure with a one-dimensional supramolecular chain through C-H…π interactions.In the asymmetric unit two Sn（Ⅳ） atoms assume similar trigonal bipyramidal coordination geometry.Two aminobenzoate groups coordinate to the terminal Sn（Ⅳ） atoms.The deprotonated methanol molecule bridges two independent Sn（Ⅳ） atoms.A half of lattice water molecule is disorderly filled in the cavity formed by Sn（Ⅳ） complexes.展开更多
基金Supported by the National Natural Science Foundation of China(No.2 0 2 710 2 5 ) and the Natural Science Foundation ofShandong Province(No.Z2 0 0 1B0 2
文摘A series of bis{oxo bis[heteroaromatic carboxylatodibenzyltin(Ⅳ)]} complexes {[(PhCH 2) 2Sn· (O 2CR)] 2O} 2[where R=2 furyl, 2 (2 furyl)vinyl, 2 (5 tert butyl)furyl, 2 thiophenyl, 2 pyridinyl, 3 pyridinyl , 4 pyridinyl, 3 indolyl, 3 indolylmethyl, 3 indolylpropyl] was synthesized by the reactions of heteroaromatic carboxylic acids with dibenzyltin(Ⅳ) oxide. All the complexes were characterized by elemental analysis, IR, and NMR spectra. The complexes were tested against two human tumour cell lines: MCF 7 and WiDr. The results show that they have higher activities in vitro . The crystal structure of bis{oxo bis[2 furylcarboxylatodibenzyltin(Ⅳ)]}(1) was determined by X ray diffraction. The crystal belongs to monoclinic space group P2 1/n, a =1 6641(2) nm, b =1 25073(18) nm, c =1 7193(3) nm, β= 101 951(2)° , Z=2, R 1=0 0446, wR 2=0 1100. Complex 1 is of a centrosymmetric dimer structure with a four membered central endo cyclic Sn 2O 2 unit in which the bridged oxygen atoms are tri coordinated. Each bridged oxygen atom also connects with an exo cyclic tin atom. The tin atoms are six coordinated and have a coordination geometry of a distorted octahedron. The exo cyclic tin atoms are five coordinated and have a coordination geometry of a monocapped trigonal bipyramid with a very similarly distorted mode. Four carboxylate ligands are divided into two types. The two of the four carboxylate ligands are bidentate and bridged to each pair of exo and endo cyclic tin atoms by using both the oxygen atoms. The other two are monodentate and bridged to each pair of exo and endo cyclic tin atoms but each utilizes one O atom only.
文摘A coupled chemiluminescence method for the determination of some carhoxylic acids was devel-oped, based on their enhancement the chemiluminescence light emission of the reaction of tirs(2, 2'-bipyri-dine) ruthenium(Ⅱ) and Ce(Ⅳ) in sulfuric acid medium. The conditions for their determination were opti-mized. The following detection limits were obtained: oxalic acid, 2. 67×10-8 mol/L; propandioic acld, 1.20×10-6 mol/L; pyruvic acid, 1. 35 ×10-8 mol/L; citric acid, 5.10×10-8. mol/L; barbituric acid, 2.48×10-7,mol/L. The proposed method was successfully applied to determination or oxalic acid. The coupled chemilu-minescent reaction mechanism and rate equation are proposed.
基金Supported by the National Natural Science Foundation of China (No 20873181)Taishan Scholars Construction Engineering (No ts20070704)+1 种基金Research Fund for the Doctoral Program of Higher Education of China (200804250502)Natural Science Foundation of Shandong Province (Y2008F20)
文摘The title ladder organotin carboxylate,{[（C6H5CH2）2Sn]4（p-NH2C6H4-COO）2O2（OCH3）2}·0.5H2O 1,has been synthesized and structurally characterized by elemental analyses,IR and single-crystal X-ray diffraction analysis.Complex 1 is located across on an inversion center and displays a Sn4O4 ladder-like structure with a one-dimensional supramolecular chain through C-H…π interactions.In the asymmetric unit two Sn（Ⅳ） atoms assume similar trigonal bipyramidal coordination geometry.Two aminobenzoate groups coordinate to the terminal Sn（Ⅳ） atoms.The deprotonated methanol molecule bridges two independent Sn（Ⅳ） atoms.A half of lattice water molecule is disorderly filled in the cavity formed by Sn（Ⅳ） complexes.
