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Critical Properties of Mixed Ising Spin System with Different Trimodal Transverse Fields in the Presence of Single-Ion Anisotropy
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作者 CHEN Qiang YAN Shi-Lei 《Communications in Theoretical Physics》 SCIE CAS CSCD 2006年第6期1131-1136,共6页
Within the framework of an effective field approximation, the effects of single-ion anisotropy and different trimodal transverse fields of two sublattices on the critical properties of the mixed spin-1/2 and spin-1 Is... Within the framework of an effective field approximation, the effects of single-ion anisotropy and different trimodal transverse fields of two sublattices on the critical properties of the mixed spin-1/2 and spin-1 Ising system are investigated on the simple cubic lattice. A smaller single-lon anisotropy can magnify magnetic ordering phases and a larger one can depress magnetic ordering phase for T-Ω1/2 space at low temperatures, while a smaller single-ion anisotropy can hardly change the value of critical transverse field for T-Ω1 space. On the other hand, influences of two different trimodal transverse fields concentrations on tricritical points and magnetic ordering phases take on some interesting results in T-D space. The main reason comes from the common action of single-ion anisotropy, different transverse fields and two trimodal distributions. 展开更多
关键词 critical property mixed spin system trimodal transverse field single-ion anisotropy
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Trimodality treatment in gastric and gastroesophageal junction cancers:Current approach and future perspectives
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作者 Nikolaos Charalampakis Sergios Tsakatikas +9 位作者 Dimitrios Schizas Stylianos Kykalos Maria Tolia Rodanthi Fioretzaki Georgios Papageorgiou Ioannis Katsaros Ahmed Adel Fouad Abdelhakeem Matheus Sewastjanow-Silva Jane E Rogers Jaffer A Ajani 《World Journal of Gastrointestinal Oncology》 SCIE 2022年第1期181-202,共22页
Gastric and gastroesophageal junction(GEJ)cancers represent an aggressive group of malignancies with poor prognosis even when diagnosed in relatively early stage,with an increasing incidence both in Asia and in Wester... Gastric and gastroesophageal junction(GEJ)cancers represent an aggressive group of malignancies with poor prognosis even when diagnosed in relatively early stage,with an increasing incidence both in Asia and in Western countries.These cancers are characterized by heterogeneity as a result of different pathogenetic mechanisms as shown in recent molecular analyses.Accordingly,the understanding of phenotypic and genotypic correlations/classifications has been improved.Current therapeutic strategies have also advanced and moved beyond surgical extirpation alone,with the incorporation of other treatment modalities,such as radiation and chemotherapy(including biologics).Chemoradiotherapy has been used as postoperative treatment after suboptimal gastrectomy to ensure local disease control but also improvement in survival.Preoperative chemoradiotherapy/chemotherapy has been employed to increase the chance of a successful R0 resection and pathologic complete response rate,which is associated with improved long-term outcomes.Several studies have defined various chemotherapy regimens to accompany radiation(before and after surgery).Recently,addition of immunotherapy after trimodality of gastroesophageal cancer has produced an advantage in disease-free interval.Targeted agents used in the metastatic setting are being investigated in the early setting with mixed results.The aim of this review is to summarize the existing data on trimodality approaches for gastric and GEJ cancers,highlight the remaining questions and present the current research effort addressing them. 展开更多
关键词 Gastric cancer Gastroesophageal junction cancer trimodality treatment CHEMORADIOTHERAPY SURGERY IMMUNOTHERAPY
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Safety and efficacy of trimodality therapy in patients undergoing extrapleural pneumonectomy
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作者 Servet Blükbas 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 2013年第2期130-131,共2页
Malignant pleural mesothelioma (MPM) is a rare but rapidly deadly disease (1). Macroscopic complete resection (MCR) is the goal of surgery (2). MCR seems to have the most significant impact on survival in pati... Malignant pleural mesothelioma (MPM) is a rare but rapidly deadly disease (1). Macroscopic complete resection (MCR) is the goal of surgery (2). MCR seems to have the most significant impact on survival in patients undergoing multimodality treatment for MPM. The role of surgical resection in the management of MPM remains controversial. The selection criterion to perform either extrapleural pneumonectomy (EPP) or extended/radical pleurectomy/ decortication (PD) rely not only on the cardio-pulmonary status of the patient, tumor stage and intraoperative findings but is strongly dependent also on surgeons' decision and philosophy. This is reflected by a recent survey of opinions and beliefs among 802 thoracic surgeons, in which EPP was believed to be more effective than PD (3). Nonetheless, either surgery might achieve MCR. 展开更多
关键词 Safety and efficacy of trimodality therapy in patients undergoing extrapleural pneumonectomy MPM
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Carbon dots with two-photon fluorescence imaging for efficient synergistic trimodal therapy
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作者 Yahui Zhang Haoyu Xia +6 位作者 Mengdie Yang Hairong Li Feishi Shan Yilong Chen Xue Yue Zhouyu Wang Xiaoqi Yu 《Chinese Chemical Letters》 SCIE CAS CSCD 2023年第9期171-175,共5页
Applying the fluorescent carbon dots as smart materials in anticancer therapy is of great interest.However,carbon dots for multimodal synergistic anticancer therapy,especially for the triple modality,is rarely reporte... Applying the fluorescent carbon dots as smart materials in anticancer therapy is of great interest.However,carbon dots for multimodal synergistic anticancer therapy,especially for the triple modality,is rarely reported.Herein,we successfully synthesized OCDs by citric acid and(1R,2S)-2-amino-1,2-diphenylethan-1-ol,which show aggregation-induced emission property and two-photon fluorescence imaging.Meanwhile,OCDs are ideal photosensitizers for photothermal therapy under 808 nm and TypeⅠphotodynamic therapy with white light.Hydroxyl radicals,generated by TypeⅠphotodynamic therapy based on OCDs can transform protumoral M2 macrophages into antitumoral M1 macrophages,which exhibited immunotherapy ability.The synergism trimodal of OCDs results in potent anticancer efficacy,showing great potential in cancer therapy. 展开更多
关键词 Carbon dots(CDs) Two-photon imaging Photothermal therapy(PTT) Type I photodynamic therapy(PDT) Synergistic trimodal anticancer therapy
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Catalase-like nanosystem for interlocking trimodal cancer therapy with hypoxia relief 被引量:1
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作者 Liyao Luo Lei Li +3 位作者 Cong Cong Yaqian He Zining Hao Dawei Gao 《Science China Materials》 SCIE EI CAS CSCD 2021年第4期1021-1034,共14页
Hypoxia is a hallmark of solid tumors,and it significantly impairs the overall anticancer efficacy,particularly photodynamic therapy(PDT).Herein,a catalase-like nanovesicle with near-infrared light-responsiveness,that... Hypoxia is a hallmark of solid tumors,and it significantly impairs the overall anticancer efficacy,particularly photodynamic therapy(PDT).Herein,a catalase-like nanovesicle with near-infrared light-responsiveness,that is,platinum/gold nanoshell encapsulated chlorin e6(Ce6)/resveratrol(Res)liposome(Pt@Au-Ce6/Res-Lip),was developed to surmount this intractable issue.The Pt@Au-Ce6/Res-Lip can decompose overexpressed H_(2)O_(2)in tumor microenvironment to produce vast amounts of O_(2)for further enhancement of the PDT.Under the 808 nm laser irradiation,the Au nanoshells induced hyperthermia at the lesion site to ablate tumor cells,simultaneously inducing the controlled release of photosensitizer Ce6 and chemotherapeutic agent Res.Moreover,stimulated by 660 nm laser,numerous reactive oxygen species were formed to induce apoptosis and necrosis of tumor cells.With the cascade of trimodal therapeutic modality options(chemotherapy,photothermal therapy,and PDT),the Pt@Au-Ce6/Res-Lip showed ultrahigh tumor inhabitation rate in in vitro and in vivo studies,signifying that the Pt@AuCe6/Res-Lip nanovesicle is a promising candidate for effective cancer therapy. 展开更多
关键词 HYPOXIA enhanced photodynamic therapy catalaselike HYPERTHERMIA trimodal therapeutic modality
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Outcomes of T3a Prostate Cancer with Unfavorable Prognostic Factors Treated with Brachytherapy Combined with External Radiotherapy and Hormone Therapy 被引量:2
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作者 Zhi-peng Mai Wei-gang Yan +2 位作者 Han-zhong Li Yi Zhou Zhi-en Zhou 《Chinese Medical Sciences Journal》 CAS CSCD 2015年第3期143-149,共7页
Objective To evaluate the outcomes of T3 a prostate cancer with unfavorable prognostic factors treated with permanent interstitial brachytherapy combined with external radiotherapy and hormone therapy.Methods From Jan... Objective To evaluate the outcomes of T3 a prostate cancer with unfavorable prognostic factors treated with permanent interstitial brachytherapy combined with external radiotherapy and hormone therapy.Methods From January 2003 to December 2008,38 patients classified as T3 a prostate cancer with unfavorable prognostic factors were treated with trimodality therapy(brachytherapy + external radiotherapy + hormone therapy).The prescription dose of brachytherapy and external radiotherapy were 110 Gy and 45 Gy,respectively.The duration of hormone therapy was 2-3 years.The endpoints of this study included biochemical failure-free survival(BFFS),distant metastasis-free survival(DMFS),cancer-specific survival(CSS),and overall survival(OS).Survival curves were calculated using the Kaplan-Meier method.The Log-rank test was used to identify the prognostic predictors for univariate analysis.Results The median follow-up was 71 months.The serum pre-treatment prostate-specific antigen(PSA) level ranged from 10.0 to 99.8 ng/ml(mean 56.3 ng/ml),the Gleason score ranged from 5 to 9(median 8),and the percentage of positive biopsy cores ranged from 10% to 100%(mean 65%).The 5-year BFFS,DMFS,CSS,and OS rates were 44%,69%,82%,and 76%,respectively.All biochemical failures occurred within 40 months.The percentage of positive biopsy cores was significantly correlated with BFFS,DMFS,and OS(all P=0.000),and the Gleason score with DMFS(P=0.000) and OS(P=0.001).Conclusions T3 a prostate cancer with unfavorable prognostic factors presents not so optimistic outcome.Hormone therapy should be applied to prolong the biochemical progression-free or metastasis-free survival.The percentage of positive biopsy cores and the Gleason score are significant prognostic factors. 展开更多
关键词 T3a prostatic neoplasms unfavorable trimodality therapy
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Malignant Pleural Mesothelioma: Treatment Options and Novel Therapies 被引量:2
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作者 Jeremiah T. Martin Brittany A. Zwischenberger Thomas Fabian 《Journal of Cancer Therapy》 2014年第1期60-66,共7页
Malignant pleural mesothelioma is a rare primary tumor rising from the pleura and is associated with exposure to asbestos fibers. Mesothelioma is a locally aggressive disease that usually presents at an advanced stage... Malignant pleural mesothelioma is a rare primary tumor rising from the pleura and is associated with exposure to asbestos fibers. Mesothelioma is a locally aggressive disease that usually presents at an advanced stage and has a median overall survival of 1 year. Treatment options rarely result in cure of disease and range from trimodality treatment, including chemotherapy, radiation, and surgery, to supportive care. In patients with limited local disease and good functional status, trimodality treatment with extra-pleural pneumonectomy, chemotherapy, and radiation is frequently employed. Best supportive care should be instituted for patients with metastatic disease and poor functional status. Palliative therapy focuses on control of pleural effusions with drainage techniques and pain with radiation therapy. Novel therapies are showing promise, including photodynamic therapy, immunotherapy, and molecular targeted therapy. 展开更多
关键词 MESOTHELIOMA Asbestos PLEURA trimodality TREATMENT
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Assessment of Rainfall Variations in South Region, Cameroon
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作者 Severin Mbog Mbog Bill Vaneck Bot +2 位作者 Olivier T. Sosso Lizzette Nsobih Dieudonne Bitondo 《American Journal of Climate Change》 2020年第4期410-422,共13页
This study of rainfall variation in the south region of Cameroon has as objective to evaluate the present climate trends in the south region using weather data from 1960 to 2010. To achieve this objective, daily and m... This study of rainfall variation in the south region of Cameroon has as objective to evaluate the present climate trends in the south region using weather data from 1960 to 2010. To achieve this objective, daily and monthly rainfall data were collected from the Ebolowa weather station. Results of this study show that generally, the south has an average of 1807 mm of rainfall in an average of 165 days. Two rainfall regimes were recognized, the bimodal with four seasons: two dry and two rainy seasons and occupies 88% of the region climatic system. The trimodal with six seasons three dry and three rainy seasons and occupies 22% of the region climatic system. Despite this seasonal repetition, rainfall is experienced in all the months of the year within the 50 years’ study period, with constant seasonal displacement and compensation within the seasons. Generally, there is a constant decrease in rainfall and number of days of rainfall but rainfall is decreasing faster than the number of days and the rainfall patterns are more or less irregular. 展开更多
关键词 RAINFALL VARIATIONS BIMODAL trimodal SEASON
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TriMode探测实现更高的调试效率及易用性
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作者 朱旭 《工业设计》 2009年第3期16-16,共1页
当整个团队的产品开发已到尾声的时候,项目组长让你把你负责调试的CRB板(概念参考板)拿给他看一下。也许就这一拿,你一年的工作都前功尽弃。因为通常探头是焊在触点上的,并存在一定的受力。如果在移动中有一个不小心,因焊点受力过大造... 当整个团队的产品开发已到尾声的时候,项目组长让你把你负责调试的CRB板(概念参考板)拿给他看一下。也许就这一拿,你一年的工作都前功尽弃。因为通常探头是焊在触点上的,并存在一定的受力。如果在移动中有一个不小心,因焊点受力过大造成焊材脱落,板子就此便作废了,而且这是你唯一的CRB板。你将如何面对呢? 展开更多
关键词 易用性 TriMode
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Peroxidase-mimicking evodiamine/indocyanine green nanoliposomes for multimodal imaging-guided theranostics for oral squamous cell carcinoma 被引量:5
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作者 Zheng Wei Huihui Zou +9 位作者 Gongyuan Liu Chuanhui Song Chuanchao Tang Sheng Chen Guorong Zhang Jianchuan Ran Yufeng Wang Xiteng Yin Yu Cai Wei Han 《Bioactive Materials》 SCIE 2021年第7期2144-2157,共14页
Here,evodiamine(EVO)and the photosensitizer indocyanine green(ICG)were integrated into a liposomal nanoplatform for noninvasive diagnostic imaging and combinatorial therapy against oral squamous cell carcinoma(OSCC).E... Here,evodiamine(EVO)and the photosensitizer indocyanine green(ICG)were integrated into a liposomal nanoplatform for noninvasive diagnostic imaging and combinatorial therapy against oral squamous cell carcinoma(OSCC).EVO,as an active component extracted from traditional Chinese medicine,not only functioned as an antitumor chemotherapeutic agent but was also capable of 68Ga-chelation,thus working as a contrast agent for positron emission tomography/computed tomography(PET/CT)imaging.Moreover,EVO could exhibit peroxidase-like catalytic activity,converting endogenous tumor H2O2 into cytotoxic reactive oxygen species(ROS),enabling Chemo catalytic therapy beyond the well-known chemotherapy effect of EVO.As proven by in vitro and in vivo experiments,guided by optical imaging and PET/CT imaging,we show that the theragnostic liposomes have a significant inhibiting effect on in situ tongue tumor through photodynamic therapy combined with chemodynamic chemotherapy. 展开更多
关键词 Oral squamous cell carcinoma EVODIAMINE Peroxidase-mimicking trimodal antitumor therapy
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Kinetic model of living ionic polymerization with three active species
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作者 颜德岳 叶鹏 张鸿安 《Science China Chemistry》 SCIE EI CAS 1998年第3期278-284,共7页
Various molecular parameters of the resulting polymer, such as number and weight average degrees of polymerization and polydispersity index, were derived for the ionic polymerization with a three state mechanism. Nume... Various molecular parameters of the resulting polymer, such as number and weight average degrees of polymerization and polydispersity index, were derived for the ionic polymerization with a three state mechanism. Numerical calculation indicated that the molecular weight distribution of the resultant polymer is rather narrow at high monomer conversion even though the three coexisting species possess rather different reactivities, and that additional foreign counterions result in a narrower molecular weight distribution. 展开更多
关键词 LIVING POLYMERIZATION KINETICS trimodal mechanism POLYDISPERSITY index.
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