Tropaeolum majus L. is widely known as a medicinal plant in human medicine. It belongs to the Tropaeolaceae which contains mustard oil glycosides like cruciferous plants. In the case of T. majus, the intact glucosinol...Tropaeolum majus L. is widely known as a medicinal plant in human medicine. It belongs to the Tropaeolaceae which contains mustard oil glycosides like cruciferous plants. In the case of T. majus, the intact glucosinolate glucotropaeolin showed no biological activity, but their degradation products, the isothiocyanates, did. The substances are thought to be enriched in the urinary bladder and the lungs, the active sites to develop their antimicrobial effectiveness. In animal nutrition these effects are of interest in sow management and piglet rearing. Therefore, the kinetics of benzyl-isothiocyanat (BITC) in plasma and the excretion with pig urine in response to nasturtium supplementation at different dosing regimens and galenic forms were examined. Four different groups with catheterized pigs were studied. The animals received the T. majus in different dosages (2.3, 6.9 and 13.4 mg GTL/kg BW) and different galenic forms (enteric coated tablets, pulverized tablets and powder) admixed to the feed ration as single bolus to the morning feeding. Blood and urine samples were collected within 24 h after nasturtium intake and analyzed for free BITC. The results indicated that the enteric coating was not effective in animal feeding. The concentration of BITC in tablet fed pigs was lower compared to animals fed powder or pulverized tablets. The bio-availability of the tablets was only 45% within 24 h relative to pulverized tablets. Nevertheless, the tablets could have some advantages in terms of the handling, the stability of the active substance and the dosing. Furthermore, it could be shown that all dosages yielded concentrations in urine and plasma, which can be considered to have an antimicrobial effect.展开更多
Unconventional vegetables, in general, are plants that have been largely consumed by the population at some point and, because of changes in eating behavior, now present reduced economic and social expression and have...Unconventional vegetables, in general, are plants that have been largely consumed by the population at some point and, because of changes in eating behavior, now present reduced economic and social expression and have lost ground to other vegetables. The objectives of this study were to perform phytochemical screening of the ethanol extracts of Rumex acetosa L., Tropaeolum majus L., Solanum muricatum, Stachys byzantina K. Koch and Solanum betaceum Cav. and evaluate their antioxidant potentials via the methods involving scavaging of the DPPH free radical and the ABTS radical, phosphomolybdenum and reducing power. In phytochemical screening, five species of unconventional vegetables tested positive for tannins;for sesquiterpene, lactones and other lactones. These tests were positive for Tropaeolum majus L. and Rumex acetosa L., Solanum betaceum Cav. and Solanum muricatum tested negative for steroids. Only Solanum betaceum Cav. gave positive tests for flavonoids. Among the five plant species studied, Stachys byzantina K. Koch presented the greatest antioxidant potential in all the methods evaluated.展开更多
基金supported by the Fachagentur fur Nachwachsende Rohstoffe(FNR),Gulzow,Germany
文摘Tropaeolum majus L. is widely known as a medicinal plant in human medicine. It belongs to the Tropaeolaceae which contains mustard oil glycosides like cruciferous plants. In the case of T. majus, the intact glucosinolate glucotropaeolin showed no biological activity, but their degradation products, the isothiocyanates, did. The substances are thought to be enriched in the urinary bladder and the lungs, the active sites to develop their antimicrobial effectiveness. In animal nutrition these effects are of interest in sow management and piglet rearing. Therefore, the kinetics of benzyl-isothiocyanat (BITC) in plasma and the excretion with pig urine in response to nasturtium supplementation at different dosing regimens and galenic forms were examined. Four different groups with catheterized pigs were studied. The animals received the T. majus in different dosages (2.3, 6.9 and 13.4 mg GTL/kg BW) and different galenic forms (enteric coated tablets, pulverized tablets and powder) admixed to the feed ration as single bolus to the morning feeding. Blood and urine samples were collected within 24 h after nasturtium intake and analyzed for free BITC. The results indicated that the enteric coating was not effective in animal feeding. The concentration of BITC in tablet fed pigs was lower compared to animals fed powder or pulverized tablets. The bio-availability of the tablets was only 45% within 24 h relative to pulverized tablets. Nevertheless, the tablets could have some advantages in terms of the handling, the stability of the active substance and the dosing. Furthermore, it could be shown that all dosages yielded concentrations in urine and plasma, which can be considered to have an antimicrobial effect.
基金The authors thank the Conselho Nacional de Desenvolvimento Científico e Tecnológico(CNPq)the Coordenacao de Aperfeiçoamento de Pessoal de Nível Superior(CAPES) the Fundacao de AmparoàPesquisa do Estado de Minas Gerais(FAPEMIG)for financial support,a scholarship and a PVNS fellowship(D.L.Nelson).
文摘Unconventional vegetables, in general, are plants that have been largely consumed by the population at some point and, because of changes in eating behavior, now present reduced economic and social expression and have lost ground to other vegetables. The objectives of this study were to perform phytochemical screening of the ethanol extracts of Rumex acetosa L., Tropaeolum majus L., Solanum muricatum, Stachys byzantina K. Koch and Solanum betaceum Cav. and evaluate their antioxidant potentials via the methods involving scavaging of the DPPH free radical and the ABTS radical, phosphomolybdenum and reducing power. In phytochemical screening, five species of unconventional vegetables tested positive for tannins;for sesquiterpene, lactones and other lactones. These tests were positive for Tropaeolum majus L. and Rumex acetosa L., Solanum betaceum Cav. and Solanum muricatum tested negative for steroids. Only Solanum betaceum Cav. gave positive tests for flavonoids. Among the five plant species studied, Stachys byzantina K. Koch presented the greatest antioxidant potential in all the methods evaluated.