Objective:To evaluate the clinical efficacy of sinew-regulating and bone-setting manipulation(SRBSM)combined with Xiaoyu Jiegu Powder(XYJGP)in treating knee osteoarthritis(KOA).Methods:Sixty patients were randomly div...Objective:To evaluate the clinical efficacy of sinew-regulating and bone-setting manipulation(SRBSM)combined with Xiaoyu Jiegu Powder(XYJGP)in treating knee osteoarthritis(KOA).Methods:Sixty patients were randomly divided into treatment group(30 cases)and control group(30 cases).The treatment group was treated with SRBSM combined with XYJGP and the control group was given intermediate frequency electrotherapy and XYJGP.Visual Analogue Scale(VAS).The Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC),Flexion range of motion of the knee joint,and surface electromyography(sEMG)were used to evaluate and compare the patients'knee function before and after treatment.The efficacy was observed with diagnosis and efficacy standards of TCM.Results:After treatment,compared with the same group before treatment,muscle fatigue and muscle tension decreased,pain was reduced,range of motion of the knee joint was increased,and motor function was improved(P<0.05).The improvement degree of the treatment group was better than that of the control group(P<0.05).The total effective rate of the treatment group was 96.6%(29/30),higher than that of the control group(80.0%),P<0.05.Conclusion:SRBSM combined with XYJGP can effectively reduce the pain of KOA patients,improve the range of motion of the joints,and improve the quality of life of the patients,and its curative effect is better than that of intermediate frequency electrotherapy combined with XYJGP.展开更多
Ninety-four patients with lumbar intervertebral disc herniation were enrolled in this study. Of these, 48 were treated with Feng＇s Spinal Manipulation, hot fomentation, and bed rest （treatment group）. The remaining...Ninety-four patients with lumbar intervertebral disc herniation were enrolled in this study. Of these, 48 were treated with Feng＇s Spinal Manipulation, hot fomentation, and bed rest （treatment group）. The remaining 46 patients were treated with hot fomentation and bed rest only （control group）. After 3 weeks of treatment, clinical parameters including the angle of straight-leg raising, visual analogue scale pain score, and Japanese Orthopaedic Association score for low back pain were improved. The treatment group had significantly better improvement in scores than the control group. Magnetic resonance myelography three-dimensional reconstruction imaging of the vertebral canal demonstrated that filling of the compressed nerve root sleeve with cerebrospinal fluid increased significantly in the treatment group. The diameter of the nerve root sleeve was significantly larger in the treatment group than in the control group. However, the sagittal diameter index of the herniated nucleus pulposus and the angle between the nerve root sleeve and the thecal sac did not change significantly in either the treatment or control groups. The effectiveness of Feng＇s Spinal Manipulation for the treatment of symptoms associated with lumbar intervertebral disc herniation may be attributable to the relief of nerve root compression, without affecting the herniated nucleus pulposus or changing the morphology or position of the nerve root.展开更多
Objective:To investigate the mechanism of trigger point deactivation induced by pressing manipulation in a rat model and to explore its potential regulation of the inflammatory response through the extracellular signa...Objective:To investigate the mechanism of trigger point deactivation induced by pressing manipulation in a rat model and to explore its potential regulation of the inflammatory response through the extracellular signal-regulated kinase(ERK)/nuclear factor-κB(NF-κB)pathway.Methods:Fifty male Sprague-Dawley rats were randomly divided into a blank group,a model group,a pressing manipulation group,an ERK agonist group,and a pressing manipulation+ERK agonist group,with 10 rats in each group.Except for the blank group,rats in other groups were used to establish the trigger point rat model using the blunt blow combined with the eccentric exercise method.The pressing manipulation group underwent pressing manipulation intervention at the trigger points.The ERK agonist group received an injection of recombinant human epidermal growth factor via the tail vein.The pressing manipulation+ERK agonist group received interventions from both the pressing manipulation and ERK agonist groups.The pressure pain threshold(PPT)was measured by a mechanical pain threshold detector before and after the intervention.The histological changes were evaluated by hematoxylin-eosin staining after the intervention;the expression levels of ERK,phosphorylated ERK(p-ERK),NF-κB p65(p65),phosphorylated NF-κB p65(p-p65),and phosphorylated NF-κB inhibitor(p-IκB)were detected by Western blotting;the levels of interleukin(IL)-1β,IL-6,and tumor necrosis factor(TNF)-αwere detected by enzyme-linked immunosorbent assay.Results:The PPT increased(P<0.05);the inflammatory cells disappeared;the ratios of p-ERK/ERK,p-p65/p65,and p-IκB/β-actin,also the levels of IL-1β,IL-6,and TNF-αall decreased in the pressing manipulation group after the intervention compared with the model group(P<0.05).The PPT decreased significantly(P<0.05),the inflammatory cell presence increased,and the ratios of p-ERK/ERK and p-p65/p65 were elevated(P<0.05);additionally,the levels of IL-6 and TNF-αwere significantly higher in the pressing manipulation+ERK agonist group compared with the pressing manipulation group(P<0.05).The PPT was significantly lower(P<0.05),the inflammatory cell count was higher,the ratios of p-ERK/ERK and p-IκB/β-actin and the levels of IL-1βand TNF-αwere significantly higher in the ERK agonist group compared with the pressing manipulation+ERK agonist group(P<0.05).Conclusion:Pressing manipulation can effectively alleviate inflammation and pain in trigger point model rats,potentially by inhibiting the ERK/NF-κB signaling pathway.展开更多
Objective:To evaluate the clinical efficacy of sinew-regulating bone-setting manipulations plus exercise therapy in treating chronic non-specific low back pain(CNLBP).Methods:A total of 65 CNLBP patients were divided ...Objective:To evaluate the clinical efficacy of sinew-regulating bone-setting manipulations plus exercise therapy in treating chronic non-specific low back pain(CNLBP).Methods:A total of 65 CNLBP patients were divided into two groups by the random number table method.Thirty-three cases in the treatment group were intervened by sinew-regulating bone-setting manipulations plus exercise therapy;32 cases in the control group were intervened by medium-frequency electrotherapy plus exercise therapy.Before and after treatment,visual analog scale(VAS),dynamic and static muscle endurance of low back,median frequency(MF)of surface electromyography(sEMG)and Oswestry disability index(ODI)were used to evaluate the low back function.The therapeutic efficacy was estimated after treatment.Results:The two groups each had 2 dropouts during the study.The total effective rate was 90.3%in the treatment group versus 66.7%in the control group,and the between-group difference was statistically significant(P<0.05).After treatment,the VAS score,dynamic and static muscle endurance of low back,MF of sEMG and ODI score all changed significantly in both groups(all P<0.05);all the items in the treatment group were significantly different from those in the control group(all P<0.05).Conclusion:Sinew-regulating bone-setting manipulations plus exercise therapy can effectively release pain in CNLBP patients,increase muscle endurance of the low back and improve the quality of life,and its therapeutic efficacy is more significant than that of medium-frequency electrotherapy plus exercise therapy.展开更多
The simple obesity is a common clinical disease and its incidence is increasing year by year.With the increasing pace of work,increasing pressure,and changing eating habits,the incidence of simple obesity tends to be ...The simple obesity is a common clinical disease and its incidence is increasing year by year.With the increasing pace of work,increasing pressure,and changing eating habits,the incidence of simple obesity tends to be younger.Among the treatment protocols for this disease,TCM manipulative(Tuina)therapy has remarkable curative effect and few adverse reactions,and has been well recognized.Modern research has also proposed a variety of treatment protocols with different characteristics and good curative effects.This paper reviews the related literature on simple obesity and its manipulative therapy in the past ten years,and summarizes its disease name,etiology and pathogenesis,manipulation and related therapies,so as to provide new ideas and new angles for the treatment of the simple obesity.展开更多
基金Key natural fund projects of Anhui provincial department of education(No.KJ2018A0273)。
文摘Objective:To evaluate the clinical efficacy of sinew-regulating and bone-setting manipulation(SRBSM)combined with Xiaoyu Jiegu Powder(XYJGP)in treating knee osteoarthritis(KOA).Methods:Sixty patients were randomly divided into treatment group(30 cases)and control group(30 cases).The treatment group was treated with SRBSM combined with XYJGP and the control group was given intermediate frequency electrotherapy and XYJGP.Visual Analogue Scale(VAS).The Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC),Flexion range of motion of the knee joint,and surface electromyography(sEMG)were used to evaluate and compare the patients'knee function before and after treatment.The efficacy was observed with diagnosis and efficacy standards of TCM.Results:After treatment,compared with the same group before treatment,muscle fatigue and muscle tension decreased,pain was reduced,range of motion of the knee joint was increased,and motor function was improved(P<0.05).The improvement degree of the treatment group was better than that of the control group(P<0.05).The total effective rate of the treatment group was 96.6%(29/30),higher than that of the control group(80.0%),P<0.05.Conclusion:SRBSM combined with XYJGP can effectively reduce the pain of KOA patients,improve the range of motion of the joints,and improve the quality of life of the patients,and its curative effect is better than that of intermediate frequency electrotherapy combined with XYJGP.
基金supported by grants from the Key Topics of China Traditional Chinese Medicine Scientific Research Project,General Logistics Department of Chinese PLA,No.10ZYZ125the Army Medical Science and Technology the125Scientific Research Projects,Chinese PLA,No.AKJ11J004
文摘Ninety-four patients with lumbar intervertebral disc herniation were enrolled in this study. Of these, 48 were treated with Feng＇s Spinal Manipulation, hot fomentation, and bed rest （treatment group）. The remaining 46 patients were treated with hot fomentation and bed rest only （control group）. After 3 weeks of treatment, clinical parameters including the angle of straight-leg raising, visual analogue scale pain score, and Japanese Orthopaedic Association score for low back pain were improved. The treatment group had significantly better improvement in scores than the control group. Magnetic resonance myelography three-dimensional reconstruction imaging of the vertebral canal demonstrated that filling of the compressed nerve root sleeve with cerebrospinal fluid increased significantly in the treatment group. The diameter of the nerve root sleeve was significantly larger in the treatment group than in the control group. However, the sagittal diameter index of the herniated nucleus pulposus and the angle between the nerve root sleeve and the thecal sac did not change significantly in either the treatment or control groups. The effectiveness of Feng＇s Spinal Manipulation for the treatment of symptoms associated with lumbar intervertebral disc herniation may be attributable to the relief of nerve root compression, without affecting the herniated nucleus pulposus or changing the morphology or position of the nerve root.
文摘Objective:To investigate the mechanism of trigger point deactivation induced by pressing manipulation in a rat model and to explore its potential regulation of the inflammatory response through the extracellular signal-regulated kinase(ERK)/nuclear factor-κB(NF-κB)pathway.Methods:Fifty male Sprague-Dawley rats were randomly divided into a blank group,a model group,a pressing manipulation group,an ERK agonist group,and a pressing manipulation+ERK agonist group,with 10 rats in each group.Except for the blank group,rats in other groups were used to establish the trigger point rat model using the blunt blow combined with the eccentric exercise method.The pressing manipulation group underwent pressing manipulation intervention at the trigger points.The ERK agonist group received an injection of recombinant human epidermal growth factor via the tail vein.The pressing manipulation+ERK agonist group received interventions from both the pressing manipulation and ERK agonist groups.The pressure pain threshold(PPT)was measured by a mechanical pain threshold detector before and after the intervention.The histological changes were evaluated by hematoxylin-eosin staining after the intervention;the expression levels of ERK,phosphorylated ERK(p-ERK),NF-κB p65(p65),phosphorylated NF-κB p65(p-p65),and phosphorylated NF-κB inhibitor(p-IκB)were detected by Western blotting;the levels of interleukin(IL)-1β,IL-6,and tumor necrosis factor(TNF)-αwere detected by enzyme-linked immunosorbent assay.Results:The PPT increased(P<0.05);the inflammatory cells disappeared;the ratios of p-ERK/ERK,p-p65/p65,and p-IκB/β-actin,also the levels of IL-1β,IL-6,and TNF-αall decreased in the pressing manipulation group after the intervention compared with the model group(P<0.05).The PPT decreased significantly(P<0.05),the inflammatory cell presence increased,and the ratios of p-ERK/ERK and p-p65/p65 were elevated(P<0.05);additionally,the levels of IL-6 and TNF-αwere significantly higher in the pressing manipulation+ERK agonist group compared with the pressing manipulation group(P<0.05).The PPT was significantly lower(P<0.05),the inflammatory cell count was higher,the ratios of p-ERK/ERK and p-IκB/β-actin and the levels of IL-1βand TNF-αwere significantly higher in the ERK agonist group compared with the pressing manipulation+ERK agonist group(P<0.05).Conclusion:Pressing manipulation can effectively alleviate inflammation and pain in trigger point model rats,potentially by inhibiting the ERK/NF-κB signaling pathway.
文摘Objective:To evaluate the clinical efficacy of sinew-regulating bone-setting manipulations plus exercise therapy in treating chronic non-specific low back pain(CNLBP).Methods:A total of 65 CNLBP patients were divided into two groups by the random number table method.Thirty-three cases in the treatment group were intervened by sinew-regulating bone-setting manipulations plus exercise therapy;32 cases in the control group were intervened by medium-frequency electrotherapy plus exercise therapy.Before and after treatment,visual analog scale(VAS),dynamic and static muscle endurance of low back,median frequency(MF)of surface electromyography(sEMG)and Oswestry disability index(ODI)were used to evaluate the low back function.The therapeutic efficacy was estimated after treatment.Results:The two groups each had 2 dropouts during the study.The total effective rate was 90.3%in the treatment group versus 66.7%in the control group,and the between-group difference was statistically significant(P<0.05).After treatment,the VAS score,dynamic and static muscle endurance of low back,MF of sEMG and ODI score all changed significantly in both groups(all P<0.05);all the items in the treatment group were significantly different from those in the control group(all P<0.05).Conclusion:Sinew-regulating bone-setting manipulations plus exercise therapy can effectively release pain in CNLBP patients,increase muscle endurance of the low back and improve the quality of life,and its therapeutic efficacy is more significant than that of medium-frequency electrotherapy plus exercise therapy.
基金Supported by Project of National Natural Science Foundation of China (82174525)National Training Program for College Students’Innovation and Entrepreneurship (202110199019)Jilin Provincial Training Program for College Students’Innovation and Entrepreneurship (S202110199117X)
文摘The simple obesity is a common clinical disease and its incidence is increasing year by year.With the increasing pace of work,increasing pressure,and changing eating habits,the incidence of simple obesity tends to be younger.Among the treatment protocols for this disease,TCM manipulative(Tuina)therapy has remarkable curative effect and few adverse reactions,and has been well recognized.Modern research has also proposed a variety of treatment protocols with different characteristics and good curative effects.This paper reviews the related literature on simple obesity and its manipulative therapy in the past ten years,and summarizes its disease name,etiology and pathogenesis,manipulation and related therapies,so as to provide new ideas and new angles for the treatment of the simple obesity.
