Optical memory effect-based speckle-correlated technology has been developed for reconstructing hidden objectsfrom disordered speckle patterns,achieving imaging through scattering layers.However,the lighting efficienc...Optical memory effect-based speckle-correlated technology has been developed for reconstructing hidden objectsfrom disordered speckle patterns,achieving imaging through scattering layers.However,the lighting efficiency and fieldof view of existing speckle-correlated imaging systems are limited.Here,a near-infrared low spatial coherence fiberrandom laser illumination method is proposed to address the above limitations.Through the utilization of random Rayleighscattering within dispersion-shifted fibers to provide feedback,coupled with stimulated Raman scattering for amplification,a near-infrared fiber random laser exhibiting a high spectral density and extremely low spatial coherence is generated.Based on the designed fiber random laser,speckle-correlated imaging through scattering layers is achieved,with highlighting efficiency and a large imaging field of view.This work improves the performance of speckle-correlated imagingand enriches the research on imaging through scattering medium.展开更多
BACKGROUND Previous epidemiologic investigations have consistently demonstrated a strong association between the ratio of cholesterol to total lipids in medium very-lowdensity lipoprotein(VLDL)and the occurrence of pe...BACKGROUND Previous epidemiologic investigations have consistently demonstrated a strong association between the ratio of cholesterol to total lipids in medium very-lowdensity lipoprotein(VLDL)and the occurrence of peptic ulcers(PU).However,the precise causal relationship between these factors remains ambiguous.Consequently,this study aims to elucidate the potential correlation between the ratio of cholesterol to total lipids in medium VLDL and the incidence of peptic ulcer.AIM To investigate the ratio of cholesterol to total lipids in medium very-low-density lipoprotein(VLDL)association with PU via genetic methods,guiding future clinical research.METHODS Genome-wide association study(GWAS)datasets for the ratio of cholesterol to total lipids in intermediate VLDL and peptic ulcer were retrieved from the IEU OpenGWAS project(https://gwas.mrcieu.ac.uk).For the forward Mendelian randomization(MR)analysis,72 single nucleotide polymorphisms(SNPs)were identified as instrumental variables.These SNPs were selected based on their association with the ratio of cholesterol to total lipids in intermediate VLDL,with peptic ulcer as the outcome variable.Conversely,for the inverse MR analysis,no SNPs were identified with peptic ulcer as the exposure variable and the ratio of cholesterol to total lipids in intermediate VLDL as the outcome.All MR analyses utilized inverse variance weighted(IVW)as the primary analytical method.Additionally,weighted median and MR-Egger methods were employed as supplementary analytical approaches to assess causal effects.Egger regression was used as a supplementary method to evaluate potential directional pleiotropy.Heterogeneity and multiplicity tests were conducted using the leave-one-out method to evaluate result stability and mitigate biases associated with multiple testing.RESULTS The genetically predicted ratio of cholesterol to total lipids in medium VLDL was significantly associated with an elevated risk of peptic ulcer(IVW:OR=2.557,95%CI=1.274-5.132,P=0.008).However,no causal association of peptic ulcer with the ratio of cholesterol to total lipids in medium VLDL was observed in the inverse Mendelian randomization analysis.CONCLUSION In conclusion,our study reveals a significant association between the ratio of cholesterol to total lipids in medium VLDL and an elevated risk of peptic ulcers.However,further validation through laboratory investigations and larger-scale studies is warranted to strengthen the evidence and confirm the causal relationship between these factors.展开更多
Seismic attenuation has been inherent media characteristics in which an interesting topic of research, for it reflects the seismic waves propagate. There are many factors that cause seismic wave attenuation, such as g...Seismic attenuation has been inherent media characteristics in which an interesting topic of research, for it reflects the seismic waves propagate. There are many factors that cause seismic wave attenuation, such as geometry attenuation caused by energy dissipating during propagation, friction attenuation by relative sliding among rock grains, and scattering attenuation by rock heterogeneity. In this paper we study P-wave scattering attenuation in a random elastic medium by numerical simulations from a statistical point of view. A random elastic medium model is built based on general stochastic process theory. Then a staggered-grid pseudo-spectral method is used to simulate wave propagation. Scattering attenuation is estimated by the spectral ratio method based on virtual detector records. Random elastic media numerical scatter results with various heterogeneity levels show that the higher heterogeneous levels cause greater scattering attenuation. When the scatter sizes are smaller than a wave length, the larger scatters give a greater attenuation. Finally, we propose a method to evaluate fluid-flow attenuation in porous media. The fluid- flow attenuation is derived from total attenuation and scattering attenuation in random porous media and the attenuation is estimated quantitatively. Results show that in the real seismic frequency range when the heterogeneous scale is about 10^1 meters (less than one wave length), scattering attenuation is larger than fluid-tlow attenuation in random porous media and scattering attenuation is the main factor of seismic attenuation in real heterogeneous porous media.展开更多
By using the spectrum expanding theory of random processes and Hudson's crack model,we developed a random medium model for rocks with spatial random distributed number density of cracks. This model could connect t...By using the spectrum expanding theory of random processes and Hudson's crack model,we developed a random medium model for rocks with spatial random distributed number density of cracks. This model could connect the micro-parameters of the cracks with the macro- mechanical properties, and can be effectively applied to model the real inhomogeneous medium. Numerical example indicates that the random distribution characters could be different for different elastic constants under the same random distribution of number density of cracks. By changing the value of the autocorrelation length pair, it is possible to model the difference of the distribution in the two coordinate directions. Numerical modeling results for seismic wave propagating in rocks with random distributed fractures using a staggered high-order finite-difference (SHOFD) are also presented.展开更多
We investigate the influence of coating layer on acoustic wave propagation in a dispersed random medium consisting of coa.ted fibers.In the strong-scattering regime, the characteristics of wave scattering resonances a...We investigate the influence of coating layer on acoustic wave propagation in a dispersed random medium consisting of coa.ted fibers.In the strong-scattering regime, the characteristics of wave scattering resonances are found to evolve regularly with the properties of the coating layer.By theoretical calculation,frequency gaps are found in acoustic excitation spectra in a random medium.The scattering cross section results present the evolution of scattering resonances with the properties of the coating layer,which offers a good explanation for the change of the frequency gaps.The velocity of the propagation quasi-mode is also shown to depend on the filling fraction of the coating layer.We use the generalized coherent potential-approximation approach to solve acoustic wave dispersion relations in a complicated random medium consisting of coating-structure scatterers.It is shown that our model reveals subtle changes in the behavior of the acoustic wave propagating quasi-modes.展开更多
Random gain medium based on organic Rhodamine 590 (R590) laser-dye and Titanium dioxide (TiO2) suspended nanoparticles have been prepared with polymethylmethacrylate (PMMA) as a host. Spray-coated homogeneous film sam...Random gain medium based on organic Rhodamine 590 (R590) laser-dye and Titanium dioxide (TiO2) suspended nanoparticles have been prepared with polymethylmethacrylate (PMMA) as a host. Spray-coated homogeneous film samples of 22.4 μm thickness. Optimum concentrations have been determined depending on the normal fluorescence spectra which give evidence that the laser dye provides amplification and TiO2 nanoparticles act as scatter center. At the optimum concentrations, results of the random gain medium under second harmonic Nd: YAG laser excitation shows that the values of bandwidth at full width half-maximum (FWHM) and the threshold energy are about 11 nm and 10 mJ respectively.展开更多
The partially coherent beams propagating through random media have been used in the past to enhance effect of nonlinear optical interaction. Moreover, after propagation through a random (or turbulent) medium the coh...The partially coherent beams propagating through random media have been used in the past to enhance effect of nonlinear optical interaction. Moreover, after propagation through a random (or turbulent) medium the coherent beam becomes a partially coherent one. In this research, the analytical formula for the average intensity of Gaussian beam propagating through random medium is derived and the influence of coherent partiality on optical gradient force acting on dielectric particle rounded by a random media is investigated.展开更多
In order to study the scale characteristics of heterogeneities in complex media, a random medium is constructed using a statistical method and by changing model parameters (autocorrelation lengths a and b), the scal...In order to study the scale characteristics of heterogeneities in complex media, a random medium is constructed using a statistical method and by changing model parameters (autocorrelation lengths a and b), the scales of heterogeneous geologic bodies in the horizontal and the vertical Cartesian directions may be varied in the medium. The autocorrelation lengths a and b represent the mean scale of heterogeneous geologic bodies in the horizontal and vertical Cartesian directions in the randQm medium, respectively. Based on this model, the relationship between model autocorrelation lengths and heterogeneous geologic body scales is studied by horizontal velocity variation and standard deviation. The horizontal velocity variation research shows that velocities are in random perturbation. The heterogeneous geologic body scale increases with increasing autocorrelation length. The recursion equation for the relationship between autocorrelation lengths and heterogeneous geologic body scales is determined from the velocity standard deviation research and the actual heterogeneous geologic body scale magnitude can be estimated by the equation.展开更多
Here,a plasmon-enhanced random laser was achieved by incorporating gold nanostars(NS) into disordered polymer and Cd Se/Zn S quantum dots(QDs) gain medium films,in which the surface plasmon resonance of gold NS ca...Here,a plasmon-enhanced random laser was achieved by incorporating gold nanostars(NS) into disordered polymer and Cd Se/Zn S quantum dots(QDs) gain medium films,in which the surface plasmon resonance of gold NS can greatly enhance the scattering cross section and bring a large gain volume.The random distribution of gold NS in the gain medium film formed a laser-mode resonator.Under a single-pulse pumping,the scattering center of gold NS-based random laser exhibits enhanced performance of a lasing threshold of 0.8 m J/cm^2 and a full width as narrow as 6 nm at half maximum.By utilizing the local enhancement characteristic of the electric field at the sharp apexes of the gold NS,the emission intensity of the random laser was increased.In addition,the gold NS showed higher thermal stability than the silver nanoparticles,withstanding high temperature heating up to 200?C.The results of metal nanostructures with enriched hot spots and excellent temperature stability have tremendous potential applications in the fields of biological identification,medical diagnostics,lighting,and display devices.展开更多
This paper surveys models and statistical properties of random systems of hard particles. Such systems appear frequently in materials science, biology and elsewhere. In mathematical-statistical investigations, simulat...This paper surveys models and statistical properties of random systems of hard particles. Such systems appear frequently in materials science, biology and elsewhere. In mathematical-statistical investigations, simulations of such structures play an important role. In these simulations various methods and models are applied, namely the RSA model, sedimentation and collective rearrangement algorithms, molecular dynamics, and Monte Carlo methods such as the Metropolis-Hastings algorithm. The statistical description of real and simulated particle systems uses ideas of the mathematical theories of random sets and point processes. This leads to characteristics such as volume fraction or porosity, covariance, contact distribution functions, specific connectivity number from the random set approach and intensity, pair correlation function and mark correlation functions from the point process approach. Some of them can be determined stereologically using planar sections, while others can only be obtained using three-dimensional data and 3D image analysis. They are valuable tools for fitting models to empirical data and, consequently, for understanding various materials, biological structures, porous media and other practically important spatial structures.展开更多
基金supported by the National Natural Science Foundation of China(Grant Nos.62375040 and 11974071)the Sichuan Science and Technology Program(Grant Nos.2022ZYD0108 and 2023JDRC0030).
文摘Optical memory effect-based speckle-correlated technology has been developed for reconstructing hidden objectsfrom disordered speckle patterns,achieving imaging through scattering layers.However,the lighting efficiency and fieldof view of existing speckle-correlated imaging systems are limited.Here,a near-infrared low spatial coherence fiberrandom laser illumination method is proposed to address the above limitations.Through the utilization of random Rayleighscattering within dispersion-shifted fibers to provide feedback,coupled with stimulated Raman scattering for amplification,a near-infrared fiber random laser exhibiting a high spectral density and extremely low spatial coherence is generated.Based on the designed fiber random laser,speckle-correlated imaging through scattering layers is achieved,with highlighting efficiency and a large imaging field of view.This work improves the performance of speckle-correlated imagingand enriches the research on imaging through scattering medium.
文摘BACKGROUND Previous epidemiologic investigations have consistently demonstrated a strong association between the ratio of cholesterol to total lipids in medium very-lowdensity lipoprotein(VLDL)and the occurrence of peptic ulcers(PU).However,the precise causal relationship between these factors remains ambiguous.Consequently,this study aims to elucidate the potential correlation between the ratio of cholesterol to total lipids in medium VLDL and the incidence of peptic ulcer.AIM To investigate the ratio of cholesterol to total lipids in medium very-low-density lipoprotein(VLDL)association with PU via genetic methods,guiding future clinical research.METHODS Genome-wide association study(GWAS)datasets for the ratio of cholesterol to total lipids in intermediate VLDL and peptic ulcer were retrieved from the IEU OpenGWAS project(https://gwas.mrcieu.ac.uk).For the forward Mendelian randomization(MR)analysis,72 single nucleotide polymorphisms(SNPs)were identified as instrumental variables.These SNPs were selected based on their association with the ratio of cholesterol to total lipids in intermediate VLDL,with peptic ulcer as the outcome variable.Conversely,for the inverse MR analysis,no SNPs were identified with peptic ulcer as the exposure variable and the ratio of cholesterol to total lipids in intermediate VLDL as the outcome.All MR analyses utilized inverse variance weighted(IVW)as the primary analytical method.Additionally,weighted median and MR-Egger methods were employed as supplementary analytical approaches to assess causal effects.Egger regression was used as a supplementary method to evaluate potential directional pleiotropy.Heterogeneity and multiplicity tests were conducted using the leave-one-out method to evaluate result stability and mitigate biases associated with multiple testing.RESULTS The genetically predicted ratio of cholesterol to total lipids in medium VLDL was significantly associated with an elevated risk of peptic ulcer(IVW:OR=2.557,95%CI=1.274-5.132,P=0.008).However,no causal association of peptic ulcer with the ratio of cholesterol to total lipids in medium VLDL was observed in the inverse Mendelian randomization analysis.CONCLUSION In conclusion,our study reveals a significant association between the ratio of cholesterol to total lipids in medium VLDL and an elevated risk of peptic ulcers.However,further validation through laboratory investigations and larger-scale studies is warranted to strengthen the evidence and confirm the causal relationship between these factors.
基金supported by the State Key Program of National Natural Science of China (Grant No. 40839901)
文摘Seismic attenuation has been inherent media characteristics in which an interesting topic of research, for it reflects the seismic waves propagate. There are many factors that cause seismic wave attenuation, such as geometry attenuation caused by energy dissipating during propagation, friction attenuation by relative sliding among rock grains, and scattering attenuation by rock heterogeneity. In this paper we study P-wave scattering attenuation in a random elastic medium by numerical simulations from a statistical point of view. A random elastic medium model is built based on general stochastic process theory. Then a staggered-grid pseudo-spectral method is used to simulate wave propagation. Scattering attenuation is estimated by the spectral ratio method based on virtual detector records. Random elastic media numerical scatter results with various heterogeneity levels show that the higher heterogeneous levels cause greater scattering attenuation. When the scatter sizes are smaller than a wave length, the larger scatters give a greater attenuation. Finally, we propose a method to evaluate fluid-flow attenuation in porous media. The fluid- flow attenuation is derived from total attenuation and scattering attenuation in random porous media and the attenuation is estimated quantitatively. Results show that in the real seismic frequency range when the heterogeneous scale is about 10^1 meters (less than one wave length), scattering attenuation is larger than fluid-tlow attenuation in random porous media and scattering attenuation is the main factor of seismic attenuation in real heterogeneous porous media.
文摘By using the spectrum expanding theory of random processes and Hudson's crack model,we developed a random medium model for rocks with spatial random distributed number density of cracks. This model could connect the micro-parameters of the cracks with the macro- mechanical properties, and can be effectively applied to model the real inhomogeneous medium. Numerical example indicates that the random distribution characters could be different for different elastic constants under the same random distribution of number density of cracks. By changing the value of the autocorrelation length pair, it is possible to model the difference of the distribution in the two coordinate directions. Numerical modeling results for seismic wave propagating in rocks with random distributed fractures using a staggered high-order finite-difference (SHOFD) are also presented.
基金Supported by the National Natural Science Foundation of China under Grant Nos 11374066 and 11374068the High-Level Personnel Training Project in Guangdong Provincethe Natural Science Foundation of Guangdong Province under Grant No S2012020010885
文摘We investigate the influence of coating layer on acoustic wave propagation in a dispersed random medium consisting of coa.ted fibers.In the strong-scattering regime, the characteristics of wave scattering resonances are found to evolve regularly with the properties of the coating layer.By theoretical calculation,frequency gaps are found in acoustic excitation spectra in a random medium.The scattering cross section results present the evolution of scattering resonances with the properties of the coating layer,which offers a good explanation for the change of the frequency gaps.The velocity of the propagation quasi-mode is also shown to depend on the filling fraction of the coating layer.We use the generalized coherent potential-approximation approach to solve acoustic wave dispersion relations in a complicated random medium consisting of coating-structure scatterers.It is shown that our model reveals subtle changes in the behavior of the acoustic wave propagating quasi-modes.
文摘Random gain medium based on organic Rhodamine 590 (R590) laser-dye and Titanium dioxide (TiO2) suspended nanoparticles have been prepared with polymethylmethacrylate (PMMA) as a host. Spray-coated homogeneous film samples of 22.4 μm thickness. Optimum concentrations have been determined depending on the normal fluorescence spectra which give evidence that the laser dye provides amplification and TiO2 nanoparticles act as scatter center. At the optimum concentrations, results of the random gain medium under second harmonic Nd: YAG laser excitation shows that the values of bandwidth at full width half-maximum (FWHM) and the threshold energy are about 11 nm and 10 mJ respectively.
文摘The partially coherent beams propagating through random media have been used in the past to enhance effect of nonlinear optical interaction. Moreover, after propagation through a random (or turbulent) medium the coherent beam becomes a partially coherent one. In this research, the analytical formula for the average intensity of Gaussian beam propagating through random medium is derived and the influence of coherent partiality on optical gradient force acting on dielectric particle rounded by a random media is investigated.
基金sponsored by the 973 Program (No. 2009CB219505)the Talents Introduction Special Project of Guangdong Ocean University (No. 0812182)
文摘In order to study the scale characteristics of heterogeneities in complex media, a random medium is constructed using a statistical method and by changing model parameters (autocorrelation lengths a and b), the scales of heterogeneous geologic bodies in the horizontal and the vertical Cartesian directions may be varied in the medium. The autocorrelation lengths a and b represent the mean scale of heterogeneous geologic bodies in the horizontal and vertical Cartesian directions in the randQm medium, respectively. Based on this model, the relationship between model autocorrelation lengths and heterogeneous geologic body scales is studied by horizontal velocity variation and standard deviation. The horizontal velocity variation research shows that velocities are in random perturbation. The heterogeneous geologic body scale increases with increasing autocorrelation length. The recursion equation for the relationship between autocorrelation lengths and heterogeneous geologic body scales is determined from the velocity standard deviation research and the actual heterogeneous geologic body scale magnitude can be estimated by the equation.
基金Project supported by the National Key Research and Development Program of China(Grant No.2017YFA0205800)the National Natural Science Foundation of China(Grant Nos.11734005,61307066,and 61450110442)+3 种基金the Natural Science Foundation of Jiangsu Province,China(Grant No.BK20130630)the Doctoral Fund of Ministry of Education of China(Grant No.20130092120024)the Innovation Fund of School of Electronic Science and Engineering,Southeast University,China(Grant No.2242015KD006)the Scientific Research Foundation of Graduate School of Southeast University,China(Grant Nos.YBJJ1513 and YBJJ1613)
文摘Here,a plasmon-enhanced random laser was achieved by incorporating gold nanostars(NS) into disordered polymer and Cd Se/Zn S quantum dots(QDs) gain medium films,in which the surface plasmon resonance of gold NS can greatly enhance the scattering cross section and bring a large gain volume.The random distribution of gold NS in the gain medium film formed a laser-mode resonator.Under a single-pulse pumping,the scattering center of gold NS-based random laser exhibits enhanced performance of a lasing threshold of 0.8 m J/cm^2 and a full width as narrow as 6 nm at half maximum.By utilizing the local enhancement characteristic of the electric field at the sharp apexes of the gold NS,the emission intensity of the random laser was increased.In addition,the gold NS showed higher thermal stability than the silver nanoparticles,withstanding high temperature heating up to 200?C.The results of metal nanostructures with enriched hot spots and excellent temperature stability have tremendous potential applications in the fields of biological identification,medical diagnostics,lighting,and display devices.
文摘This paper surveys models and statistical properties of random systems of hard particles. Such systems appear frequently in materials science, biology and elsewhere. In mathematical-statistical investigations, simulations of such structures play an important role. In these simulations various methods and models are applied, namely the RSA model, sedimentation and collective rearrangement algorithms, molecular dynamics, and Monte Carlo methods such as the Metropolis-Hastings algorithm. The statistical description of real and simulated particle systems uses ideas of the mathematical theories of random sets and point processes. This leads to characteristics such as volume fraction or porosity, covariance, contact distribution functions, specific connectivity number from the random set approach and intensity, pair correlation function and mark correlation functions from the point process approach. Some of them can be determined stereologically using planar sections, while others can only be obtained using three-dimensional data and 3D image analysis. They are valuable tools for fitting models to empirical data and, consequently, for understanding various materials, biological structures, porous media and other practically important spatial structures.