Magnetic resonance neurography (MRN) is used to determine traumatic changes within nervous trunks. A 21-year-old male was treated for neurotmesis of the left sciatic nerve. At 41 days after micro-neurosurgery, two-d...Magnetic resonance neurography (MRN) is used to determine traumatic changes within nervous trunks. A 21-year-old male was treated for neurotmesis of the left sciatic nerve. At 41 days after micro-neurosurgery, two-dimensional MRN (2-D MRN) was performed with plain and contrast scans in the left injured sciatic nerve. More than 2 years after trauma, 2-D MRN images were collected to re-examine the left sciatic nerve. Results from the first 2-D MRN examination revealed a swollen left sciatic nerve. Furthermore, TlWl revealed a local nodule with slightly high intensity, and T2WI revealed hyperintensity. The nodule was significantly enhanced. Upon 2-D MRN re-examination more than 2 years after injury, the injured left sciatic nerve trunk was thinner, and the nodule margin in the left sciatic trunk was clearer. The supero-inferior diameter was enlarged by 2 mm compared with previous films. The degree of enhancement became weaker in the nodule. 2-D MRN revealed continuity, traumatic neuroma, and atrophy of the injured sciatic nerves in detail. Thin-slice technique was crucial for this method, as well as fat-suppressed and blood flow-suppressed imaging.展开更多
The optimal velocity encoding of phase-contrast magnetic resonance angiography (PC MRA) in measuring cerebral blood flow volume (BFV) ranges from 60 to 80 cm/s. To verify the accuracy of two-dimensional (2D) PC ...The optimal velocity encoding of phase-contrast magnetic resonance angiography (PC MRA) in measuring cerebral blood flow volume (BFV) ranges from 60 to 80 cm/s. To verify the accuracy of two-dimensional (2D) PC MRA, the present study localized the region of interest at blood vessels of the neck using PC MRA based on three-dimensional time-of-flight sequences, and the velocity encoding was set to 80 cm/s. Results of the measurements showed that the error rate was 7.0±6.0% in the estimation of BFV in the internal carotid artery, the external carotid artery and the ipsilateral common carotid artery. There was no significant difference, and a significant correlation in BFV between internal carotid artery + external carotid artery and ipsilateral common carotid artery. In addition, the BFV of the common carotid artery was correlated with that of the ipsilateral internal carotid artery. The main error was attributed to the external carotid artery and its branches. Therefore, after selecting the appropriate scanning parameters and protocols, 2D PC MRA is more accurate in the determination of BFV in the carotid arteries.展开更多
AIM: To test the incremental value of 3T magnetic resonance neurography(MRN) in a series of unilateral radiculopathy patients with non-contributory magnetic resonance imaging(MRI).METHODS: Ten subjects(3 men,7 women; ...AIM: To test the incremental value of 3T magnetic resonance neurography(MRN) in a series of unilateral radiculopathy patients with non-contributory magnetic resonance imaging(MRI).METHODS: Ten subjects(3 men,7 women; mean age54 year and range 22-74 year) with unilateral lumbar radiculopathy and with previous non-contributory lumbar spine MRI underwent lumbosacral(LS) plexus MRN over a period of one year. Lumbar spine MRI performed as part of the MRN LS protocol as well as bilateral L4-S1 nerves,sciatic,femoral and lateral femoral cutaneous nerves were evaluated in each subject for neuropathy findings on both anatomic(nerve signal,course and caliber alterations) and diffusion tensor imaging(DTI)tensor maps(nerve signal and caliber alterations).Minimum fractional anisotropy(FA) and mean apparent diffusion coeffcient(ADC) of L4-S2 nerve roots,sciatic and femoral nerves were recorded.RESULTS: All anatomic studies and 80% of DTI imaging received a good-excellent imaging quality grading. In a blinded evaluation,all 10 examinations demonstrated neural and/or neuromuscular abnormality corresponding to the site of radiculopathy. A number of contributory neuropathy findings including double crush syndrome were observed. On DTI tensor maps,nerve signal and caliber alterations were more conspicuous. Although individual differences were observed among neuropathic appearing nerve(lower FA and increased ADC) as compared to its contralateral counterpart,there were no significant mean differences on statistical comparison of LS plexus nerves,femoral and sciatic nerves(P > 0.05).CONCLUSION: MRN of LS plexus is useful modality for the evaluation of patients with non-contributory MRI of lumbar spine as it can incrementally delineate the etiology and provide direct objective and non-invasive evidence of neuromuscular pathology.展开更多
AIM: To evaluate the pudendal nerve segments that could be identified on magnetic resonance neurography(MRN) before and after surgical marking of different nerve segments.METHODS: The hypothesis for this study was tha...AIM: To evaluate the pudendal nerve segments that could be identified on magnetic resonance neurography(MRN) before and after surgical marking of different nerve segments.METHODS: The hypothesis for this study was that pudendal nerve and its branches would be more easily seen after the surgical nerve marking. Institutional board approval was obtained. One male and one female cadaver pelvis were obtained from the anatomy board and were scanned using 3 Tesla MRI scanner using MR neurography sequences. All possible pudendal nerve branches were identified. The cadavers were then sent to the autopsy lab and were surgically dissected by a peripheral nerve surgeon and an anatomist to identify the pudendal nerve branches. Radiological markers were placed along the course of the pudendal nerve and its branches. The cadavers were then closed and rescanned using the same MRN protocol as the premarking scan. The remaining pudendal nerve branches were attempted to be identified using the radiological markers. All scans were read by an experienced musculoskeletal radiologist.RESULTS: The pre-marking MR Neurography scans clearly showed the pudendal nerve at its exit from the lumbosacral plexus in the sciatic notch, at the level of the ischial spine and in the Alcock's Canal in both cadavers. Additionally, the right hemorrhoidal branch could be identified in the male pelvis cadaver. The perineal and distal genital branches could not be identified. On post-marking scans, the markers were used as identifiable structures. The location of the perineal branch, the hemorroidal branch and the dorsal nerve to penis(in male cadaver)/clitoris(in female cadaver) could be seen. However, the visualization of these branches was suboptimal. The contralateral corresponding nerves were poorly seen despite marking on the surgical side. The nerve was best seen on axial T1W and T2W SPAIR images. The proximal segment could be seen well on 3D DW PSIF sequence. T2W SPACE was not very useful in visualization of this small nerve or its branches.CONCLUSION: Proximal pudendal nerve is easily seen on MR neurography, however it is not possible to identify distal branches of the pudendal nerve even after surgical marking.展开更多
Among the layered two-dimensional ferromagnetic materials(2D FMs),due to a relatively high T_(C),the van der Waals(vdW)Fe_(3)GeTe_(2)(FGT)crystal is of great importance for investigating its distinct magnetic properti...Among the layered two-dimensional ferromagnetic materials(2D FMs),due to a relatively high T_(C),the van der Waals(vdW)Fe_(3)GeTe_(2)(FGT)crystal is of great importance for investigating its distinct magnetic properties.Here,we have carried out static and dynamic magnetization measurements of the FGT crystal with a Curie temperature TC≈204 K.The M-H hysteresis loops with in-plane and out-of-plane orientations show that FGT has a strong perpendicular magnetic anisotropy with the easy axis along its c-axis.Moreover,we have calculated the uniaxial magnetic anisotropy constant(K_(1))from the SQUID measurements.The dynamic magnetic properties of FGT have been probed by utilizing the high sensitivity electron-spin-resonance(ESR)spectrometer at cryogenic temperatures.Based on an approximation of single magnetic domain mode,the K_(1)and the effective damping constant(αeff)have also been determined from the out-of-plane angular dependence of ferromagnetic resonance(FMR)spectra obtained at the temperature range of 185 K to T_(C).We have found large magnetic damping with the effective damping constantαeff~0.58 along with a broad linewidth(ΔH_(pp)>1000 Oe at 9.48 GHz,H||c-axis).Our results provide useful dynamics information for the development of FGT-based spintronic devices.展开更多
Characterizing the trajectory of the healthy aging brain and exploring age-related structural changes in the brain can help deepen our understanding of the mechanism of brain aging.Currently,most structural magnetic r...Characterizing the trajectory of the healthy aging brain and exploring age-related structural changes in the brain can help deepen our understanding of the mechanism of brain aging.Currently,most structural magnetic resonance imaging literature explores brain aging merely from the perspective of morphological features,which cannot fully utilize the grayscale values containing important intrinsic information about brain structure.In this study,we propose the construction of two-dimensional horizontal visibility graphs based on the pixel intensity values of the gray matter slices directly.Normalized network structure entropy(NNSE)is then introduced to quantify the overall heterogeneities of these graphs.The results demonstrate a decrease in the NNSEs of gray matter with age.Compared with the middle-aged and the elderly,the larger values of the NNSE in the younger group may indicate more homogeneous network structures,smaller differences in importance between nodes and thus a more powerful ability to tolerate intrusion.In addition,the hub nodes of different adult age groups are primarily located in the precuneus,cingulate gyrus,superior temporal gyrus,inferior temporal gyrus,parahippocampal gyrus,insula,precentral gyrus and postcentral gyrus.Our study can provide a new perspective for understanding and exploring the structural mechanism of brain aging.展开更多
BACKGROUND Neuralgic amyotrophy(NA)is a rare disease with sudden upper limb pain followed by affected muscle weakness.The most commonly affected area in NA is the upper part of the brachial plexus,and the paraspinal m...BACKGROUND Neuralgic amyotrophy(NA)is a rare disease with sudden upper limb pain followed by affected muscle weakness.The most commonly affected area in NA is the upper part of the brachial plexus,and the paraspinal muscles are rarely affected(1.5%),making these cases difficult to distinguish from cervical radiculopathy.CASE SUMMARY A 76-year-old male presented to the emergency department with left hip pain post-fall.After undergoing left femoral neck fracture surgery,he experienced sudden left shoulder pain for 10 days with subsequent left arm weakness.Cervical spine computed tomography revealed mild right asymmetric intervertebral disc bulging with a decreased C5-6disc space.Three weeks later,an electrodiagnostic study confirmed brachial plexopathy findings involving the cervical root.Magnetic resonance neurography was performed for a differential diagnosis.Contrast enhancement was identified at the upper trunk of the brachial plexus,including the C5 nerve root.A suprascapular nerve hourglass-like focal constriction(HLFC)was also identified,confirming NA.After being diagnosed with NA,the patient received 15 mg prednisolone,twice daily,for 3 weeks.Physical therapy was initiated,including left arm strengthening exercises and electrical stimulation therapy.Left shoulder muscle strength significantly improved one CONCLUSION NA's unique features like HLFC and paraspinal involvement are crucial for accurate diagnosis,avoiding confusion with cervical radiculopathy.展开更多
目的:探讨三维可变翻转角快速自旋回波序列(three dimensional sampling perfection with application optimized contrasts by using different flip angle evolution,3D-SPACE)神经成像技术显示腰骶丛肿瘤性病变的价值。方法:回顾性分...目的:探讨三维可变翻转角快速自旋回波序列(three dimensional sampling perfection with application optimized contrasts by using different flip angle evolution,3D-SPACE)神经成像技术显示腰骶丛肿瘤性病变的价值。方法:回顾性分析2018年1月至2023年12月间16例累及腰骶丛神经的肿瘤性病变患者的MRI资料,所有病例均经病理检查确诊。测量病灶的最大径,统计病灶数目,观察病变累及的腰骶丛神经位置,统计受累神经数目,描述肿瘤与神经间的关系。结果:16例患者中,单发病灶10例,多发病灶6例,病灶平均最大径为(57.1±37.2) mm。累及单根神经5例,累及多根神经11例。肿瘤与神经关系,沿神经生长5例,神经受压5例,神经受肿瘤侵袭、包绕6例。结论:3D-SPACE神经成像技术能清晰、直观地显示受累神经的位置、数目及肿瘤与神经间的关系,在显示腰骶丛肿瘤性病变的定位及诊断中具有重要价值。展开更多
文摘Magnetic resonance neurography (MRN) is used to determine traumatic changes within nervous trunks. A 21-year-old male was treated for neurotmesis of the left sciatic nerve. At 41 days after micro-neurosurgery, two-dimensional MRN (2-D MRN) was performed with plain and contrast scans in the left injured sciatic nerve. More than 2 years after trauma, 2-D MRN images were collected to re-examine the left sciatic nerve. Results from the first 2-D MRN examination revealed a swollen left sciatic nerve. Furthermore, TlWl revealed a local nodule with slightly high intensity, and T2WI revealed hyperintensity. The nodule was significantly enhanced. Upon 2-D MRN re-examination more than 2 years after injury, the injured left sciatic nerve trunk was thinner, and the nodule margin in the left sciatic trunk was clearer. The supero-inferior diameter was enlarged by 2 mm compared with previous films. The degree of enhancement became weaker in the nodule. 2-D MRN revealed continuity, traumatic neuroma, and atrophy of the injured sciatic nerves in detail. Thin-slice technique was crucial for this method, as well as fat-suppressed and blood flow-suppressed imaging.
基金the Medical Program of Scientific & Technical Foundation in Xiamen in 2008, No. 3502Z20084028
文摘The optimal velocity encoding of phase-contrast magnetic resonance angiography (PC MRA) in measuring cerebral blood flow volume (BFV) ranges from 60 to 80 cm/s. To verify the accuracy of two-dimensional (2D) PC MRA, the present study localized the region of interest at blood vessels of the neck using PC MRA based on three-dimensional time-of-flight sequences, and the velocity encoding was set to 80 cm/s. Results of the measurements showed that the error rate was 7.0±6.0% in the estimation of BFV in the internal carotid artery, the external carotid artery and the ipsilateral common carotid artery. There was no significant difference, and a significant correlation in BFV between internal carotid artery + external carotid artery and ipsilateral common carotid artery. In addition, the BFV of the common carotid artery was correlated with that of the ipsilateral internal carotid artery. The main error was attributed to the external carotid artery and its branches. Therefore, after selecting the appropriate scanning parameters and protocols, 2D PC MRA is more accurate in the determination of BFV in the carotid arteries.
文摘AIM: To test the incremental value of 3T magnetic resonance neurography(MRN) in a series of unilateral radiculopathy patients with non-contributory magnetic resonance imaging(MRI).METHODS: Ten subjects(3 men,7 women; mean age54 year and range 22-74 year) with unilateral lumbar radiculopathy and with previous non-contributory lumbar spine MRI underwent lumbosacral(LS) plexus MRN over a period of one year. Lumbar spine MRI performed as part of the MRN LS protocol as well as bilateral L4-S1 nerves,sciatic,femoral and lateral femoral cutaneous nerves were evaluated in each subject for neuropathy findings on both anatomic(nerve signal,course and caliber alterations) and diffusion tensor imaging(DTI)tensor maps(nerve signal and caliber alterations).Minimum fractional anisotropy(FA) and mean apparent diffusion coeffcient(ADC) of L4-S2 nerve roots,sciatic and femoral nerves were recorded.RESULTS: All anatomic studies and 80% of DTI imaging received a good-excellent imaging quality grading. In a blinded evaluation,all 10 examinations demonstrated neural and/or neuromuscular abnormality corresponding to the site of radiculopathy. A number of contributory neuropathy findings including double crush syndrome were observed. On DTI tensor maps,nerve signal and caliber alterations were more conspicuous. Although individual differences were observed among neuropathic appearing nerve(lower FA and increased ADC) as compared to its contralateral counterpart,there were no significant mean differences on statistical comparison of LS plexus nerves,femoral and sciatic nerves(P > 0.05).CONCLUSION: MRN of LS plexus is useful modality for the evaluation of patients with non-contributory MRI of lumbar spine as it can incrementally delineate the etiology and provide direct objective and non-invasive evidence of neuromuscular pathology.
文摘AIM: To evaluate the pudendal nerve segments that could be identified on magnetic resonance neurography(MRN) before and after surgical marking of different nerve segments.METHODS: The hypothesis for this study was that pudendal nerve and its branches would be more easily seen after the surgical nerve marking. Institutional board approval was obtained. One male and one female cadaver pelvis were obtained from the anatomy board and were scanned using 3 Tesla MRI scanner using MR neurography sequences. All possible pudendal nerve branches were identified. The cadavers were then sent to the autopsy lab and were surgically dissected by a peripheral nerve surgeon and an anatomist to identify the pudendal nerve branches. Radiological markers were placed along the course of the pudendal nerve and its branches. The cadavers were then closed and rescanned using the same MRN protocol as the premarking scan. The remaining pudendal nerve branches were attempted to be identified using the radiological markers. All scans were read by an experienced musculoskeletal radiologist.RESULTS: The pre-marking MR Neurography scans clearly showed the pudendal nerve at its exit from the lumbosacral plexus in the sciatic notch, at the level of the ischial spine and in the Alcock's Canal in both cadavers. Additionally, the right hemorrhoidal branch could be identified in the male pelvis cadaver. The perineal and distal genital branches could not be identified. On post-marking scans, the markers were used as identifiable structures. The location of the perineal branch, the hemorroidal branch and the dorsal nerve to penis(in male cadaver)/clitoris(in female cadaver) could be seen. However, the visualization of these branches was suboptimal. The contralateral corresponding nerves were poorly seen despite marking on the surgical side. The nerve was best seen on axial T1W and T2W SPAIR images. The proximal segment could be seen well on 3D DW PSIF sequence. T2W SPACE was not very useful in visualization of this small nerve or its branches.CONCLUSION: Proximal pudendal nerve is easily seen on MR neurography, however it is not possible to identify distal branches of the pudendal nerve even after surgical marking.
基金Project supported by the National Key Research and Development Program of China(Grant No.2016YFA0300803)the National Natural Science Foundation of China(Grant Nos.11774150,12074178,61427812,11774160,61805116,and 61271077)the Natural Science Foundation of Jiangsu Province of China(Grant Nos.BK20192006,BK20180056,and BK20200307).
文摘Among the layered two-dimensional ferromagnetic materials(2D FMs),due to a relatively high T_(C),the van der Waals(vdW)Fe_(3)GeTe_(2)(FGT)crystal is of great importance for investigating its distinct magnetic properties.Here,we have carried out static and dynamic magnetization measurements of the FGT crystal with a Curie temperature TC≈204 K.The M-H hysteresis loops with in-plane and out-of-plane orientations show that FGT has a strong perpendicular magnetic anisotropy with the easy axis along its c-axis.Moreover,we have calculated the uniaxial magnetic anisotropy constant(K_(1))from the SQUID measurements.The dynamic magnetic properties of FGT have been probed by utilizing the high sensitivity electron-spin-resonance(ESR)spectrometer at cryogenic temperatures.Based on an approximation of single magnetic domain mode,the K_(1)and the effective damping constant(αeff)have also been determined from the out-of-plane angular dependence of ferromagnetic resonance(FMR)spectra obtained at the temperature range of 185 K to T_(C).We have found large magnetic damping with the effective damping constantαeff~0.58 along with a broad linewidth(ΔH_(pp)>1000 Oe at 9.48 GHz,H||c-axis).Our results provide useful dynamics information for the development of FGT-based spintronic devices.
基金Project supported by the Natural Science Foundation of Jiangsu Province,China(Grant No.BK20190736)the Young Scientists Fund of the National Natural Science Foundation of China(Grant Nos.81701346 and 61603198)Qinglan Team of Universities in Jiangsu Province(Jiangsu Teacher Letter[2020]10 and Jiangsu Teacher Letter[2021]11).
文摘Characterizing the trajectory of the healthy aging brain and exploring age-related structural changes in the brain can help deepen our understanding of the mechanism of brain aging.Currently,most structural magnetic resonance imaging literature explores brain aging merely from the perspective of morphological features,which cannot fully utilize the grayscale values containing important intrinsic information about brain structure.In this study,we propose the construction of two-dimensional horizontal visibility graphs based on the pixel intensity values of the gray matter slices directly.Normalized network structure entropy(NNSE)is then introduced to quantify the overall heterogeneities of these graphs.The results demonstrate a decrease in the NNSEs of gray matter with age.Compared with the middle-aged and the elderly,the larger values of the NNSE in the younger group may indicate more homogeneous network structures,smaller differences in importance between nodes and thus a more powerful ability to tolerate intrusion.In addition,the hub nodes of different adult age groups are primarily located in the precuneus,cingulate gyrus,superior temporal gyrus,inferior temporal gyrus,parahippocampal gyrus,insula,precentral gyrus and postcentral gyrus.Our study can provide a new perspective for understanding and exploring the structural mechanism of brain aging.
文摘BACKGROUND Neuralgic amyotrophy(NA)is a rare disease with sudden upper limb pain followed by affected muscle weakness.The most commonly affected area in NA is the upper part of the brachial plexus,and the paraspinal muscles are rarely affected(1.5%),making these cases difficult to distinguish from cervical radiculopathy.CASE SUMMARY A 76-year-old male presented to the emergency department with left hip pain post-fall.After undergoing left femoral neck fracture surgery,he experienced sudden left shoulder pain for 10 days with subsequent left arm weakness.Cervical spine computed tomography revealed mild right asymmetric intervertebral disc bulging with a decreased C5-6disc space.Three weeks later,an electrodiagnostic study confirmed brachial plexopathy findings involving the cervical root.Magnetic resonance neurography was performed for a differential diagnosis.Contrast enhancement was identified at the upper trunk of the brachial plexus,including the C5 nerve root.A suprascapular nerve hourglass-like focal constriction(HLFC)was also identified,confirming NA.After being diagnosed with NA,the patient received 15 mg prednisolone,twice daily,for 3 weeks.Physical therapy was initiated,including left arm strengthening exercises and electrical stimulation therapy.Left shoulder muscle strength significantly improved one CONCLUSION NA's unique features like HLFC and paraspinal involvement are crucial for accurate diagnosis,avoiding confusion with cervical radiculopathy.
文摘目的:探讨三维可变翻转角快速自旋回波序列(three dimensional sampling perfection with application optimized contrasts by using different flip angle evolution,3D-SPACE)神经成像技术显示腰骶丛肿瘤性病变的价值。方法:回顾性分析2018年1月至2023年12月间16例累及腰骶丛神经的肿瘤性病变患者的MRI资料,所有病例均经病理检查确诊。测量病灶的最大径,统计病灶数目,观察病变累及的腰骶丛神经位置,统计受累神经数目,描述肿瘤与神经间的关系。结果:16例患者中,单发病灶10例,多发病灶6例,病灶平均最大径为(57.1±37.2) mm。累及单根神经5例,累及多根神经11例。肿瘤与神经关系,沿神经生长5例,神经受压5例,神经受肿瘤侵袭、包绕6例。结论:3D-SPACE神经成像技术能清晰、直观地显示受累神经的位置、数目及肿瘤与神经间的关系,在显示腰骶丛肿瘤性病变的定位及诊断中具有重要价值。