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Assessment of Calf Skeletal Muscle Stiffness in Diabetic Nephropathy Patients with Medial Tibial Stress Syndrome by Two-Dimensional Shear Wave Elastography
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作者 Lei Wang Lei Ran 《Proceedings of Anticancer Research》 2023年第5期11-16,共6页
Objective:To explore the feasibility of two-dimensional shear wave elastography in evaluating calf skeletal muscle stiffness in diabetic nephropathy patients with medial tibial stress syndrome.Methods:A total of 48 di... Objective:To explore the feasibility of two-dimensional shear wave elastography in evaluating calf skeletal muscle stiffness in diabetic nephropathy patients with medial tibial stress syndrome.Methods:A total of 48 diabetic nephropathy patients with medial tibial stress syndrome from January 2020 to December 2022 were included as the study group,and 48 patients with diabetic nephropathy during the same period were included as the control group.Both groups were detected by two-dimensional shear wave elastography with ultrasonic equipment,and Young‘s modulus of the tibialis anterior muscle,tibialis posterior muscle,and gastrocnemius muscle were observed and analyzed in the two groups.Results:The Young‘s modulus values of tibialis anterior muscle,tibialis posterior muscle,and gastrocnemius muscle in the study group were significantly lower than those in the control group(P<0.05).Conclusion:Two-dimensional shear wave elastography is feasible for the evaluation of calf skeletal muscle stiffness in diabetic nephropathy patients with medial tibial stress syndrome,and has high accuracy and repeatability.This technique can be used to diagnose,treat and monitor muscle lesions in patients with diabetic nephropathy,and can also be used to assess muscle fatigue and exercise capacity,which has broad application prospects. 展开更多
关键词 two-dimensional shear wave elastography Diabetic nephropathy Medial tibial stress syndrome
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Diagnostic problems in two-dimensional shear wave elastography of the liver 被引量:4
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作者 Hiroko Naganuma Hideaki Ishida +3 位作者 Atsushi Uno Hiroshi Nagai Hidekatsu Kuroda Masahiro Ogawa 《World Journal of Radiology》 CAS 2020年第5期76-86,共11页
Two-dimensional shear wave elastography(2D-SWE)is used in the clinical setting for observation of the liver.Unfortunately,a wide spectrum of artifactual images are frequently encountered in 2D-SWE,the precise mechanis... Two-dimensional shear wave elastography(2D-SWE)is used in the clinical setting for observation of the liver.Unfortunately,a wide spectrum of artifactual images are frequently encountered in 2D-SWE,the precise mechanisms of which remain incompletely understood.This review was designed to present many of the artifactual images seen in 2D-SWE of the liver and to analyze them by computer simulation models that support clinical observations.Our computer simulations yielded the following suggestions:(1)When performing 2D-SWE in patients with chronic hepatic disease,especially liver cirrhosis,it is recommended to measure shear wave values through the least irregular hepatic surface;(2)The most useful 2D-SWE in patients with focal lesion will detect lesions that are poorly visible on B-mode ultrasound and will differentiate true tumors from pseudo-tumors(e.g.,irregular fatty change);and(3)Measurement of shear wave values in the area posterior to a focal lesion must be avoided. 展开更多
关键词 two-dimensional shear wave elastography ULTRASOUND ARTIFACTS Liver cirrhosis Liver tumor Computer simulation model
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Differential diagnosis of different types of solid focal liver lesions using two-dimensional shear wave elastography 被引量:3
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作者 Jia Guo Dong Jiang +4 位作者 Yi Qian Jiao Yu Yi-Jun Gu Yu-Qing Zhou Hui-Ping Zhang 《World Journal of Gastroenterology》 SCIE CAS 2022年第32期4715-4724,共10页
BACKGROUND The clinical management and prognosis differ between benign and malignant solid focal liver lesions(FLLs),as well as among different pathological types of malignant FLLs.Accurate diagnosis of the possible t... BACKGROUND The clinical management and prognosis differ between benign and malignant solid focal liver lesions(FLLs),as well as among different pathological types of malignant FLLs.Accurate diagnosis of the possible types of solid FLLs is important.Our previous study confirmed the value of shear wave elastography(SWE)using maximal elasticity(Emax)as the parameter in the differential diagnosis between benign and malignant FLLs.However,the value of SWE in the differential diagnosis among different pathological types of malignant FLLs has not been proved.AIM To explore the value of two-dimensional SWE(2D-SWE)using Emax in the differential diagnosis of FLLs,especially among different pathological types of malignant FLLs.METHODS All the patients enrolled in this study were diagnosed as benign,malignant or undetermined FLLs by conventional ultrasound.Emax of FLLs and the periphery of FLLs was measured using 2D-SWE and compared between benign and malignant FLLs or among different pathological types of malignant FLLs.RESULTS The study included 32 benign FLLs in 31 patients and 100 malignant FLLs in 96 patients,including 16 cholangiocellular carcinomas(CCCs),72 hepatocellular carcinomas(HCCs)and 12 liver metastases.Thirty-five FLLs were diagnosed as undetermined by conventional ultrasound.There were significant differences between Emax of malignant(2.21±0.57 m/s)and benign(1.59±0.37 m/s)FLLs(P=0.000),and between Emax of the periphery of malignant(1.52±0.39 m/s)and benign(1.36±0.44 m/s)FLLs(P=0.040).Emax of liver metastases(2.73±0.99 m/s)was significantly higher than that of CCCs(2.14±0.34 m/s)and HCCs(2.14±0.46 m/s)(P=0.002).The sensitivity,specificity and accuracy were 71.00%,84.38%and 74.24%respectively,using Emax>1.905 m/s(AUC 0.843)to diagnose as malignant and 23 of 35(65.74%)FLLs with undetermined diagnosis by conventional ultrasound were diagnosed correctly.CONCLUSION Malignant FLLs were stiffer than benign ones and liver metastases were stiffer than primary liver carcinomas.2D-SWE with Emax was a useful complement to conventional ultrasound for the differential diagnosis of FLLs. 展开更多
关键词 Focal liver lesions Conventional ultrasound two-dimensional shear wave elastography Differential diagnosis
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Model for liver hardness using two-dimensional shear wave elastography,durometer,and preoperative biomarkers 被引量:1
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作者 Bing-Jie Ju Ming Jin +4 位作者 Yang Tian Xiang Zhen De-Xing Kong Wei-Lin Wang Sheng Yan 《World Journal of Gastrointestinal Surgery》 SCIE 2021年第2期127-140,共14页
BACKGROUND Post-hepatectomy liver failure(PHLF)increases morbidity and mortality after liver resection for patients with advanced liver fibrosis and cirrhosis.Preoperative liver stiffness using two-dimensional shear w... BACKGROUND Post-hepatectomy liver failure(PHLF)increases morbidity and mortality after liver resection for patients with advanced liver fibrosis and cirrhosis.Preoperative liver stiffness using two-dimensional shear wave elastography(2D-SWE)is widely used to evaluate the degree of fibrosis.However,the 2D-SWE results were not accurate.A durometer measures hardness by quantifying the ability of a material to locally resist the intrusion of hard objects into its surface.However,the durometer score can only be obtained during surgery.To measure correlations among 2D-SWE,palpation by surgeons,and durometermeasured objective liver hardness and to construct a liver hardness regression model.METHODS We enrolled 74 hepatectomy patients with liver hardness in a derivation cohort.Tactile-based liver hardness scores(0-100)were determined through palpation of the liver tissue by surgeons.Additionally,liver hardness was measured using a durometer.Correlation coefficients for durometer-measured hardness and preoperative parameters were calculated.Multiple linear regression models were constructed to select the best predictive durometer scale.Receiver operating characteristic(ROC)curves and univariate and multivariate analyses were used to calculate the best model’s prediction of PHLF and risk factors for PHLF,respectively.A separate validation cohort(n=162)was used to evaluate the model.RESULTS The stiffness measured using 2D-SWE and palpation scale had good linear correlation with durometer-measured hardness(Pearson rank correlation coefficient 0.704 and 0.729,respectively,P<0.001).The best model for the durometer scale(hardness scale model)was based on stiffness,hepatitis B virus surface antigen,and albumin level and had an R2 value of 0.580.The area under the ROC for the durometer and hardness scale for PHLF prediction were 0.807(P=0.002)and 0.785(P=0.005),respectively.The optimal cutoff value of the durometer and hardness scale was 27.38(sensitivity=0.900,specificity=0.660)and 27.87(sensitivity=0.700,specificity=0.787),respectively.Patients with a hardness scale score of>27.87 were at a significantly higher risk of PHLF with hazard ratios of 7.835(P=0.015).The model’s PHLF predictive ability was confirmed in the validation cohort.CONCLUSION Liver stiffness assessed by 2D-SWE and palpation correlated well with durometer hardness values.The multiple linear regression model predicted durometer hardness values and PHLF. 展开更多
关键词 HEPATECTOMY Liver Hardness Durometer two-dimensional shear wave elastography Post-hepatectomy liver failure Liver failure
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Quantitative and noninvasive assessment of chronic liver diseases using two-dimensional shear wave elastography 被引量:17
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作者 Li-Ting Xie Chun-Hong Yan +2 位作者 Qi-Yu Zhao Meng-Na He Tian-An Jiang 《World Journal of Gastroenterology》 SCIE CAS 2018年第9期957-970,共14页
Two-dimensional shear wave elastography(2D-SWE) is a rapid, simple and novel noninvasive method that has been proposed for assessing hepatic fibrosis in patients with chronic liver diseases(CLDs) based on measurements... Two-dimensional shear wave elastography(2D-SWE) is a rapid, simple and novel noninvasive method that has been proposed for assessing hepatic fibrosis in patients with chronic liver diseases(CLDs) based on measurements of liver stiffness. 2 D-SWE can be performed easily at the bedside or in an outpatient clinic and yields immediate results with good reproducibility. Furthermore, 2 D-SWE was an efficient method for evaluating liver fibrosis in small to moderately sized clinical trials. However, the quality criteria for the staging of liver fibrosis are not yet well defined. Liver fibrosis is the main pathological basis of liver stiffness and a key step in the progression from CLD to cirrhosis; thus, the management of CLD largely depends on the extent and progression of liver fibrosis. 2 D-SWE appears to be an excellent tool for the early detection of cirrhosis and may have prognostic value in this context. Because 2 D-SWE has high patient acceptance, it could be useful for monitoring fibrosis progression and regression in individual cases. However, multicenter data are needed to support its use. This study reviews the current status and future perspectives of 2 D-SWE for assessments of liver fibrosis and discusses the technical advantages and limitations that impact its effective and rational clinical use. 展开更多
关键词 ELASTOGRAPHY shear wave CHRONIC LIVER disease LIVER FIBROSIS
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Role of two-dimensional shear wave elastography in chronic liver diseases: A narrative review 被引量:6
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作者 Jae Yoon Jeong Young Seo Cho Joo Hyun Sohn 《World Journal of Gastroenterology》 SCIE CAS 2018年第34期3849-3860,共12页
Liver biopsy is the gold standard for evaluating the degree of liver fibrosis in patients with chronic liver disease. However, due to the many limitations of liver biopsy, there has been much interest in the use of no... Liver biopsy is the gold standard for evaluating the degree of liver fibrosis in patients with chronic liver disease. However, due to the many limitations of liver biopsy, there has been much interest in the use of noninvasive techniques for this purpose. Among these techniques real-time two-dimensional shear wave elastography(2D-SWE) has the advantage of measuring tissue elasticity with the guidance of B-mode images. Recently, many studies have been conducted on the application of 2D-SWE in patients with various liver diseases, and their validity has been confirmed. Here, we briefly discuss the role of 2D-SWE in patients with chronic liver diseases, particularly aspects of the examination techniques and clinical applications. 展开更多
关键词 shear wave ELASTOGRAPHY LIVER disease LIVER FIBROSIS PORTAL HYPERTENSION Hepatocelluar CARCINOMA
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The utility of two-dimensional shear wave elastography and texture analysis for monitoring liver fibrosis in rat model 被引量:3
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作者 Li-Hong Gu Guang-Xiang Gu +2 位作者 Ping Wan Feng-Hua Li Qiang Xia 《Hepatobiliary & Pancreatic Diseases International》 SCIE CAS CSCD 2021年第1期46-52,共7页
Background:Liver fibrosis is a common pathological change caused by a variety of etiologies.Early diagnosis and timely treatment can reverse or delay disease progression and improve the prognosis.This study aimed to a... Background:Liver fibrosis is a common pathological change caused by a variety of etiologies.Early diagnosis and timely treatment can reverse or delay disease progression and improve the prognosis.This study aimed to assess the potential utility of two-dimensional shear wave elastography and texture analysis in dynamic monitoring of the progression of liver fibrosis in rat model.Methods:Twenty rats were divided into control group(n=4)and experimental groups(n=4 per group)with carbon tetrachloride administration for 2,3,4,and 6 weeks.The liver stiffness measurement was performed by two-dimensional shear wave elastography,while the optimal texture analysis subsets to distinguish fibrosis stage were generated by MaZda.The results of elastography and texture analysis were validated through comparing with histopathology.Results:Liver stiffness measurement was 6.09±0.31 kPa in the control group and 7.10±0.41 kPa,7.80±0.93 kPa,8.64±0.93 kPa,9.91±1.13 kPa in the carbon tetrachloride induced groups for 2,3,4,6 weeks,respectively(P<0.05).By texture analysis,histogram and co-occurrence matrix had the most frequency texture parameters in staging liver fibrosis.Receiver operating characteristic curve of liver elasticity showed that the sensitivity and specificity were 95.0%and 92.5%to discriminate liver fibrosis and non-fibrosis,respectively.In texture analysis,five optimal parameters were selected to classify liver fibrosis and non-fibrosis.Conclusions:Two-dimensional shear wave elastography showed potential applications for noninvasive monitoring of the progression of hepatic fibrosis,even in mild fibrosis.Texture analysis can further extract and quantify the texture features in ultrasonic image,which was a supplementary to further visual information and acquired high diagnostic accuracy for severe fibrosis. 展开更多
关键词 shear wave elastography ULTRASOUND Texture analysis FIBROSIS Rat
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Comparison of point and two-dimensional shear wave elastography of the spleen in healthy subjects 被引量:1
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作者 Friederike Nowotny Julian Schmidberger +2 位作者 Patrycja Schlingeloff Andreas Binzberger Wolfgang Kratzer 《World Journal of Radiology》 2021年第5期137-148,共12页
BACKGROUND Few systematic comparative studies of the different methods of physical elastography of the spleen are currently available.AIM To compare point shear wave and two-dimensional elastography of the spleen cons... BACKGROUND Few systematic comparative studies of the different methods of physical elastography of the spleen are currently available.AIM To compare point shear wave and two-dimensional elastography of the spleen considering the anatomical location(upper,hilar,and lower pole).METHODS As part of a prospective clinical study,healthy volunteers were examined for splenic elasticity using four different ultrasound devices between May 2015 and April 2017.The devices used for point shear wave elastography were from Siemens(S 3000)and Philips(Epiq 7),and those used for two-dimensional shear wave elastography were from GE(Logiq E9)and Toshiba(Aplio 500).In addition,two different software versions(5.0 and 6.0)were evaluated for the Toshiba ultrasound device(Aplio 500).The study consisted of three arms:A,B,and C.RESULTS In study arm A,200 subjects were evaluated(78 males and 122 females,mean age 27.9±8.1 years).In study arm B,113 subjects were evaluated(38 men and 75 women,mean age 26.0±6.3 years).In study arm C,44 subjects were enrolled.A significant correlation of the shear wave velocities at the upper third of the spleen(r=0.33088,P<0.0001)was demonstrated only for the Philips Epiq 7 device compared to the Siemens Acuson S 3000.In comparisons of the other ultrasound devices(GE,Siemens,Toshiba),no comparable results could be obtained for any anatomical position of the spleen.The influencing factors age,gender,and body mass index did not show a clear correlation with the measured shear wave velocities.CONCLUSION The absolute values of the shear wave elastography measurements of the spleen and the two different elastography methods are not comparable between different manufacturers or models. 展开更多
关键词 ULTRASONOGRAPHY ELASTOGRAPHY SPLEEN Healthy subjects Acoustic radiation force impulse two-dimensional shear-wave elastography Point shear wave elastography
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Photoacoustic elastography based on laser-excited shear wave
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作者 Yang Liu Ruoyi Shi +1 位作者 Gang Li Mingjian Sun 《Journal of Innovative Optical Health Sciences》 SCIE EI CSCD 2024年第3期56-72,共17页
Elastography can be used as a diagnostic method for quantitative characterization of tissue hardness information and thus,differential changes in pathophysiological states of tissues.In this study,we propose a new met... Elastography can be used as a diagnostic method for quantitative characterization of tissue hardness information and thus,differential changes in pathophysiological states of tissues.In this study,we propose a new method for shear wave elastography(SWE)based on laser-excited shear wave,called photoacoustic shear wave elastography(PASWE),which combines photoacoustic(PA)technology with ultrafast ultrasound imaging.By using a focused laser to excite shear waves and ultrafast ultrasonic imaging for detection,high-frequency excitation of shear waves and noncontact elastic imaging can be realized.The laser can stimulate the tissue with the light absorption characteristic to produce the thermal expansion,thus producing the shear wave.The frequency of shear wave induced by laser is higher and the frequency band is wider.By tracking the propagation of shear wave,Young’s modulus of tissue is reconstructed in the whole shear wave propagation region to further evaluate the elastic information of tissue.The feasibility of the method is verified by experiments.Compared with the experimental results of supersonic shear imaging(SSI),it is proved that the method can be used for quantitative elastic imaging of the phantoms.In addition,compared with the SSI method,this method can realize the noncontact excitation of the shear wave,and the frequency of the shear wave excited by the laser is higher than that of the acoustic radiation force(ARF),so the spatial resolution is higher.Compared to the traditional PA elastic imaging method,this method can obtain a larger imaging depth under the premise of ensuring the imaging resolution,and it has potential application value in the clinical diagnosis of diseases requiring noncontact quantitative elasticity. 展开更多
关键词 ELASTOGRAPHY shear wave PHOTOACOUSTIC Young's modulus
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Predicting hepatocellular carcinoma: A new non-invasive model based on shear wave elastography
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作者 Dong Jiang Yi Qian +9 位作者 Yi-Jun Gu Ru Wang Hua Yu Hui Dong Dong-Yu Chen Yan Chen Hao-Zheng Jiang Bi-Bo Tan Min Peng Yi-Ran Li 《World Journal of Gastroenterology》 SCIE CAS 2024年第25期3166-3178,共13页
BACKGROUND Integrating conventional ultrasound features with 2D shear wave elastography(2D-SWE)can potentially enhance preoperative hepatocellular carcinoma(HCC)predictions.AIM To develop a 2D-SWE-based predictive mod... BACKGROUND Integrating conventional ultrasound features with 2D shear wave elastography(2D-SWE)can potentially enhance preoperative hepatocellular carcinoma(HCC)predictions.AIM To develop a 2D-SWE-based predictive model for preoperative identification of HCC.METHODS A retrospective analysis of 884 patients who underwent liver resection and pathology evaluation from February 2021 to August 2023 was conducted at the Oriental Hepatobiliary Surgery Hospital.The patients were divided into the modeling group(n=720)and the control group(n=164).The study included conventional ultrasound,2D-SWE,and preoperative laboratory tests.Multiple logistic regression was used to identify independent predictive factors for RESULTS In the modeling group analysis,maximal elasticity(Emax)of tumors and their peripheries,platelet count,cirrhosis,and blood flow were independent risk indicators for malignancies.These factors yielded an area under the curve of 0.77(95%confidence interval:0.73-0.81)with 84%sensitivity and 61%specificity.The model demonstrated good calibration in both the construction and validation cohorts,as shown by the calibration graph and Hosmer-Lemeshow test(P=0.683 and P=0.658,respectively).Additionally,the mean elasticity(Emean)of the tumor periphery was identified as a risk factor for microvascular invasion(MVI)in malignant liver tumors(P=0.003).Patients receiving antiviral treatment differed significantly in platelet count(P=0.002),Emax of tumors(P=0.033),Emean of tumors(P=0.042),Emax at tumor periphery(P<0.001),and Emean at tumor periphery(P=0.003).CONCLUSION 2D-SWE’s hardness value serves as a valuable marker for enhancing the preoperative diagnosis of malignant liver lesions,correlating significantly with MVI and antiviral treatment efficacy. 展开更多
关键词 shear wave elastography Predicting model Microvascular invasion Antiviral treatment Hepatocellular carcinoma
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Seismic anisotropy and upper mantle dynamics in Alaska:A review of shear wave splitting analyses
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作者 Zhaofeng Jin Yuchen Yang +7 位作者 Muhammad Ishaidir Siregar Zihao Mu S.M.Ariful Islam Qichao Zhao Dan Wang Fan Zhang Xugang Yang Liwei Song 《Earthquake Research Advances》 CSCD 2024年第2期72-81,共10页
Shear wave splitting(SWS)is regarded as the most effective geophysical method to delineate mantle flow fields by detecting seismic azimuthal anisotropy in the earth's upper mantle,especially in tectonically active... Shear wave splitting(SWS)is regarded as the most effective geophysical method to delineate mantle flow fields by detecting seismic azimuthal anisotropy in the earth's upper mantle,especially in tectonically active regions such as subduction zones.The Aleutian-Alaska subduction zone has a convergence rate of approximately 50 mm/yr,with a trench length reaching nearly 2800 km.Such a long subduction zone has led to intensive continental deformation and numerous strong earthquakes in southern and central Alaska,while northern Alaska is relatively inactive.The sharp contrast makes Alaska a favorable locale to investigate the impact of subduction on mantle dynamics.Moreover,the uniqueness of this subduction zone,including the unusual subducting type,varying slab geometry,and atypical magmatic activity and composition,has intrigued the curiosity of many geoscientists.To identify different sources of seismic anisotropy beneath the Alaska region and probe the influence of a geometrically varying subducting slab on mantle dynamics,extensive SWS analyses have been conducted in the past decades.However,the insufficient station and azimuthal coverage,especially in early studies,not only led to some conflicting results but also strongly limited the in-depth investigation of layered anisotropy and the estimation of anisotropy depth.With the completion of the Transportable Array project in Alaska,recent studies have revealed more detailed mantle structures and characteristics based on the dense station coverage and newly collected massive seismic data.In this study,we review significant regional-and continental-scale SWS studies in the Alaska region and conclude the mantle flow fields therein,to understand how a geometrically varying subducting slab alters the regional mantle dynamics.The summarized mantle flow mechanisms are believed to be conducive to the understanding of seismic anisotropy patterns in other subduction zones with a complicated tectonic setting. 展开更多
关键词 Seismic anisotropy shear wave splitting Mantle flow Alaska subduction zone SLAB
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Comparison of resistive index and shear-wave elastography in the evaluation of chronic kidney allograft dysfunction
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作者 Ameet Kumar Jesrani Syed M Faiq +5 位作者 Rahma Rashid Tariq Ali Kalwar Rehan Mohsin Tahir Aziz Nida Amin Khan Muhammed Mubarak 《World Journal of Transplantation》 2024年第1期154-163,共10页
BACKGROUND Detection of early chronic changes in the kidney allograft is important for timely intervention and long-term survival.Conventional and novel ultrasound-based investigations are being increasingly used for ... BACKGROUND Detection of early chronic changes in the kidney allograft is important for timely intervention and long-term survival.Conventional and novel ultrasound-based investigations are being increasingly used for this purpose with variable results.AIM To compare the diagnostic performance of resistive index(RI)and shear wave elastography(SWE)in the diagnosis of chronic fibrosing changes of kidney allograft with histopathological results.METHODS This is a cross-sectional and comparative study.A total of 154 kidney transplant recipients were included in this study,which was conducted at the Departments of Transplantation and Radiology,Sindh Institute of Urology and Transplantation,Karachi,Pakistan,from August 2022 to February 2023.All consecutive patients with increased serum creatinine levels and reduced glomerular filtration rate(GFR)after three months of transplantation were enrolled in this study.SWE and RI were performed and the findings of these were evaluated against the kidney allograft biopsy results to determine their diagnostic utility.RESULTS The mean age of all patients was 35.32±11.08 years.Among these,126(81.8%)were males and 28(18.2%)were females.The mean serum creatinine in all patients was 2.86±1.68 mg/dL and the mean estimated GFR was 35.38±17.27 mL/min/1.73 m2.Kidney allograft biopsy results showed chronic changes in 55(37.66%)biopsies.The sensitivity,specificity,positive predictive value(PPV),and negative predictive value(NPV)of SWE for the detection of chronic allograft damage were 93.10%,96.87%%,94.73%,and 95.87%,respectively,and the diagnostic accuracy was 95.45%.For RI,the sensitivity,specificity,PPV,and NPV were 76.92%,83.33%,70.17%,and 87.62%,respectively,and the diagnostic accuracy was 81.16%.CONCLUSION The results from this study show that SWE is more sensitive and specific as compared to RI in the evaluation of chronic allograft damage.It can be of great help during the routine follow-up of kidney transplant recipients for screening and early detection of chronic changes and selecting patients for allograft biopsy. 展开更多
关键词 shear wave SONOELASTOGRAPHY Resistive index Chronic allograft changes Biopsy HISTOPATHOLOGY
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Shear wave splitting analysis of local earthquakes from dense arrays in Shimian,Sichuan 被引量:2
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作者 Sha Liu Baofeng Tian 《Earthquake Science》 2023年第1期52-63,共12页
The Shimian area of Sichuan sits at the junction of the Bayan Har block.Sichuan-Yunnan rhombic block,and Yangtze block,where several faults intersect.This region features intense tectonic activity and frequent earthqu... The Shimian area of Sichuan sits at the junction of the Bayan Har block.Sichuan-Yunnan rhombic block,and Yangtze block,where several faults intersect.This region features intense tectonic activity and frequent earthquakes.In this study,we used local seismic waveform data recorded using dense arrays deployed in the Shimian area to obtain the shear wave splitting parameters at 55 seismic stations and thereby determine the crustal anisotropic characteristics of the region.We then analyzed the crustal stress pattern and tectonic setting and explored their relationship in the study area.Although some stations returned a polarization direction of NNW-SSE.a dominant polarization direction of NW-SE was obtained for the fast shear wave at most seismic stations in the study area.The polarization directions of the fast shear wave were highly consistent throughout the study-area.This orientation was in accordance with the direction of the regional principal compressive stress and parallel to the trend of the Xianshuihe and Daliangshan faults.The distribution of crustal anisotropy in this area was affected by the regional tectonic stress field and the fault structures.The mean delay time between fast and slow shear waves was 3.83 ms/km.slightly greater than the values obtained in other regions of Sichuan.This indicates that the crustal media in our study area had a high anisotropic strength and also reveals the influence of tectonic complexity resulting from the intersection of multiple faults on the strength of seismic anisotropy. 展开更多
关键词 shear wave splitting polarization direction of the fast shear wave regional principal compressive stress dense array Citation:Liu S and Tian BF(2023).shear wave splitting analysis of local earthquakes from dense arrays in Shimian Sichuan.
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Combining the age-male-albumin-bilirubin-platelets score and shear wave elastography stratifies carcinogenic risk in hepatitis C patients after viral clearance 被引量:1
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作者 Rion Masaoka Yoshinori Gyotoku +2 位作者 Ryosaku Shirahashi Toshikuni Suda Masaya Tamano 《World Journal of Clinical Cases》 SCIE 2023年第22期5204-5214,共11页
BACKGROUND The treatment of hepatitis C with direct-acting antiviral agents(DAAs)produces a high rate of sustained virological response(SVR)with fewer adverse events than interferon(IFN)therapy with a similar effect i... BACKGROUND The treatment of hepatitis C with direct-acting antiviral agents(DAAs)produces a high rate of sustained virological response(SVR)with fewer adverse events than interferon(IFN)therapy with a similar effect in inhibiting carcinogenesis as IFN therapy.The age-male-albumin-bilirubin-platelets(aMAP)score is useful for stratifying the risk of hepatocellular carcinoma in chronic hepatitis patients,and the velocity of shear waves(Vs)measured by shear wave elastography has also been shown to be useful for diagnosing the level of fibrotic progression in hepatitis C and predicting carcinogenic risk.Combining these two may improve the prediction of carcinogenic risk.AIM To determine whether combining the aMAP score with Vs improves carcinogenic risk stratification in medium-to-high-risk hepatitis C patients.METHODS This retrospective,observational study involved hepatitis C patients treated with DAAs who achieved SVR.Vs was measured before treatment(baseline),at the end of treatment(EOT),and 12 wk(follow-up 12)and 24 wk(follow-up 24)after treatment.The patients were followed for at least six months after EOT to determine whether cancer developed.Multiple regression analysis was used to identify factors contributing to hepatic carcinogenesis.The diagnostic performances of clinical parameters for predicting the presence of hepatocellular carcinoma were evaluated using receiver-operating characteristic(ROC)curve analyses.RESULTS A total of 279 patients(mean age 65.9 years,118 males,161 females)were included in the analysis.Multiple regression analysis was performed with carcinogenesis as the target variable and alanine aminotransferase,platelets,α-fetoprotein,Vs,and the Fib-4 index as explanatory variables;only Vs was found to be significant(P=0.0296).The cut-off value for Vs for liver carcinogenesis calculated using the ROC curve was 1.53 m/s.Carcinoma developed in 2.0%(3/151)of those with Vs<1.53 m/s and in 10.5%(9/86)of those with Vs≥1.53 m/s.CONCLUSION In hepatitis C patients after SVR,combining the aMAP score and Vs to stratify the risk of carcinogenesis is more efficient than uniform surveillance of all patients. 展开更多
关键词 Hepatitis C Hepatocellular carcinoma Direct-acting antiviral therapy shear wave elastography Sustained virological response Age-male-albumin-bilirubin-platelets score
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Comparative analysis of conventional ultrasound and shear wave elastography features in primary breast diffuse large B-cell lymphoma
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作者 Xiao-Duan Zhang Kai Zhang 《World Journal of Clinical Cases》 SCIE 2023年第33期7994-8002,共9页
BACKGROUND Primary breast diffuse large B-cell lymphoma(PB-DLBCL)is a rare subtype of non-Hodgkin lymphoma that accounts for<3%of extranodal lymphomas and 1%of breast tumors.Its diagnosis and management are challen... BACKGROUND Primary breast diffuse large B-cell lymphoma(PB-DLBCL)is a rare subtype of non-Hodgkin lymphoma that accounts for<3%of extranodal lymphomas and 1%of breast tumors.Its diagnosis and management are challenging because of its rarity,heterogeneity,and aggressive behavior.Conventional ultrasound(US)is the first-line imaging modality for breast lesions;however,it has limited specificity and accuracy for PB-DLBCL.Shear wave elastography(SWE)is a novel US technique that measures tissue stiffness and may reflect the histological characteristics and biological behavior of breast lesions.AIM To compare the conventional US and SWE features of PB-DLBCL and evaluate their diagnostic performance and prognostic value.METHODS We retrospectively reviewed the clinical data and US images of 32 patients with pathologically confirmed PB-DLBCL who underwent conventional US and SWE before treatment.We analyzed conventional US features(shape,margin,orientation,echo,posterior acoustic features,calcification,and vascularity)and SWE features(mean elasticity value,standard deviation,minimum elasticity value,maximum elasticity value,and lesion-to-fat ratio)of the PB-DLBCL lesions.Using receiver operating characteristic curve analysis,we determined the optimal cutoff values and diagnostic performance of conventional US and SWE features.We also performed a survival analysis to assess the prognostic value of conventional US and SWE features.RESULTS The results showed that the PB-DLBCL lesions were mostly irregular in shape(84.4%),microlobulated or spiculated in margins(75%),parallel in orientation(65.6%),hypoechoic in echo(87.5%),and had posterior acoustic enhancement(65.6%).Calcification was rare(6.3%)and vascularity was variable(31.3%avascular,37.5%hypovascular,and 31.3%hypervascular).The mean elasticity value of PB-DLBCL lesions was significantly higher than that of benign breast lesions(113.4±46.9 kPa vs 27.8±16.4 kPa,P<0.001).The optimal cutoff value of the mean elasticity for distinguishing PB-DLBCL from benign breast lesions was 54.5 kPa,with a sensitivity of 93.8%,specificity of 92.9%,positive predictive value of 93.8%,negative predictive value of 92.9%,and accuracy of 93.3%.The mean elasticity value was also significantly correlated with Ki-67 expression level(r=0.612,P<0.001),which is a marker of tumor proliferation and aggressiveness.Survival analysis showed that patients with higher mean elasticity values(>54.5 kPa)had worse overall survival(OS)and progression-free survival(PFS)than those with lower mean elasticity values(<54.5 kPa)(P=0.038 for OS and P=0.027 for PFS).CONCLUSION Conventional US and SWE provide useful information for diagnosing and forecasting PB-DLBCL.SWE excels in distinguishing PB-DLBCL from benign breast lesions,reflects tumor proliferation and aggressiveness,and improves disease management. 展开更多
关键词 Primary breast diffuse large B-cell lymphoma Conventional ultrasound shear wave elastography Diagnosis PROGNOSIS Tumor behavior
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Elastic Wave Scattering by Two-Dimensional Periodical Array of Cylinders 被引量:1
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作者 Mei Jun Liu Zheng-you Shi Jing 《Wuhan University Journal of Natural Sciences》 EI CAS 2002年第2期174-176,共3页
We extend the multiple-scattering theory (MST) for elastic wave scattering and propagating in two-dimensional composite. The formalism for the band structure calculation is presented by taking into account the full ve... We extend the multiple-scattering theory (MST) for elastic wave scattering and propagating in two-dimensional composite. The formalism for the band structure calculation is presented by taking into account the full vector character of the elastic wave. As a demonstration of application of the formalism we calculate the band structure of elastic wave propagating in a two-dimensional periodic arrangement of cylinders. The results manifest that the MST shows great promise in complementing the plane-wave (PW) approach for the study of elastic wave. 展开更多
关键词 elastic wave scattering band structure two-dimensional periodical arrangement multiple-scattering theory
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Optimization design of conical reaction teeth of shear wave vibroseis vibration plate
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作者 WANG Hongxiang DU Lizhi SUN Zhen 《Global Geology》 2023年第4期264-272,共9页
The vibrator plate is the link between the vibroseis vehicle and the earth,as well as the core com-ponent of the vibrator vehicle.In this paper,the coupling effect between the vibrator plate and the earth is an-alyzed... The vibrator plate is the link between the vibroseis vehicle and the earth,as well as the core com-ponent of the vibrator vehicle.In this paper,the coupling effect between the vibrator plate and the earth is an-alyzed from two aspects of reaction tooth arrangement and reaction tooth conical angle,and three groups of experimental models are optimized and designed.The model construction and numerical analysis of the shear wave vibroseis vibrator plate are carried out with ANSYS software.The motion law between the vibration plate and the earth at work was studied,the strain energy of the three experimental models in operation,the maximum displacement of particle at the same position and other reference indices were compared and ana-lyzed,with 28 conical reaction teeth were arranged on both sides.The coupling effect between the vibration plate and the earth was best when the tooth angle was 60°.Compared with the toothless vibration plate,the energy efficiency is improved by about 20%,and the coupling effect between the vibrator plate and the earth is effectively enhanced.It is found that the coupling effect is enhanced through increasing the number of reac-tion teeth of the vibration plate by increasing the coupling area between the vibration plate and the earth. 展开更多
关键词 shear wave vibroseis vibration plate conical reaction teeth
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TWO-DIMENSIONAL STRESS WAVE ANALYSIS IN INCOMPRESSIBLE ELASTIC SOLIDS 被引量:1
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作者 唐之景 丁启财 李永池 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 1989年第8期701-712,共12页
Two-dimensional stress wares in n general incompressible elastic solid are investigated. First, baxic equations for simple wares and shock waves are presented for a general strain energy junction. Then the characteris... Two-dimensional stress wares in n general incompressible elastic solid are investigated. First, baxic equations for simple wares and shock waves are presented for a general strain energy junction. Then the characteristic ware speeds and the associated characteristic vectors are deduced. It is shown that there usually exist two simple waves and two shock wares. Finally, two examples are given for the case of plane strain deformation and antiplane strain deformation, respectively. It is proved that, in the case of plane strain deformation, the oblique reflection problem of a plane shock is not solvable in general. 展开更多
关键词 two-dimensional STRESS wave ANALYSIS IN INCOMPRESSIBLE ELASTIC SOLIDS
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Analytical solutions of turbulent boundary layer beneath forward-leaning waves
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作者 Yiqin XIE Jifu ZHOU +3 位作者 Xu WANG Jinlong DUAN Yongjun LU Shouqian LI 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2024年第4期695-710,共16页
As a typical nonlinear wave,forward-leaning waves can be frequently encountered in the near-shore areas,which can impact coastal sediment transport significantly.Hence,it is of significance to describe the characteris... As a typical nonlinear wave,forward-leaning waves can be frequently encountered in the near-shore areas,which can impact coastal sediment transport significantly.Hence,it is of significance to describe the characteristics of the boundary layer beneath forward-leaning waves accurately,especially for the turbulent boundary layer.In this work,the linearized turbulent boundary layer model with a linear turbulent viscosity coefficient is applied,and the novel expression of the near-bed orbital velocity that has been worked out by the authors for forward-leaning waves of arbitrary forward-leaning degrees is further used to specify the free stream boundary condition of the bottom boundary layer.Then,a variable transformation is found so as to make the equation of the turbulent boundary layer model be solved analytically through a modified Bessel function.Consequently,an explicit analytical solution of the turbulent boundary layer beneath forward-leaning waves is derived by means of variable separation and variable transformation.The analytical solutions of the velocity profile and bottom shear stress of the turbulent boundary layer beneath forward-leaning waves are verified by comparing the present analytical results with typical experimental data available in the previous literature. 展开更多
关键词 forward-leaning wave turbulent boundary layer velocity profile bottom shear stress
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Real-time Shear Wave Elastography Assessment of Muscle Elasticity in Patients with Renal Failure
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作者 Lei Ran Lei Wang Tingting Cai 《Journal of Clinical and Nursing Research》 2023年第5期66-71,共6页
Objective:To explore the value of real-time elastic shear wave in evaluating muscle elasticity in patients with renal failure.Methods:50 patients with chronic renal failure from January 2019 to December 2022 were rand... Objective:To explore the value of real-time elastic shear wave in evaluating muscle elasticity in patients with renal failure.Methods:50 patients with chronic renal failure from January 2019 to December 2022 were randomly selected as the experimental group,and 50 healthy patients aged 21-61 during the same period were selected as the control group,and the basic information of the patients,including age,gender,body mass index,etc.,were collected.Besides,the Young's modulus of the two groups of patients were observed and analyzed.Results:The Young's modulus values of left and right gastrocnemius muscles in the experimental group were significantly lower than those in the control group(P<0.05),and there was no statistical difference between the left and right sides of the experimental group and the control group(P>0.05).Conclusion:Real-time shear wave elastography provides a non-invasive,real-time and effective tool for the assessment of muscle elasticity in patients with renal failure.Through further research and optimization,real-time shear wave elastography will play a greater role in the prevention and treatment of patients with renal failure,improving the quality of life and prognosis of patients. 展开更多
关键词 Real-time shear wave elastography Renal failure Muscle elasticity
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