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抗U1-RNP抗体和抗RNPA/RNP68抗体联合检测在自身免疫性疾病诊断中的价值
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作者 王瑛 张颐豪 +6 位作者 季玮 付燕 于雪莹 张慧 胡婷婷 沈薇 满秋红 《检验医学》 CAS 2024年第11期1066-1071,共6页
目的探讨抗U1-核糖核蛋白(RNP)抗体和抗RNPA/RNP68抗体在自身免疫性疾病(AID)诊断中的价值。方法选取2021年10月—2024年3月同济大学附属上海市第四人民医院、上海交通大学医学院附属仁济医院AID患者136例[AID组,包括混合性结缔组织病(M... 目的探讨抗U1-核糖核蛋白(RNP)抗体和抗RNPA/RNP68抗体在自身免疫性疾病(AID)诊断中的价值。方法选取2021年10月—2024年3月同济大学附属上海市第四人民医院、上海交通大学医学院附属仁济医院AID患者136例[AID组,包括混合性结缔组织病(MCTD)23例、系统性红斑狼疮(SLE)49例、干燥综合征(SS)14例、狼疮性肾炎14例、自身免疫性肝炎(AIH)17例、类风湿性关节炎(RA)19例]和非AID患者136例(非AID组),以及健康体检者100名(正常对照组)。采用流式点阵免疫发光法检测所有研究对象抗RNPA/RNP68抗体,采用免疫印迹法检测抗U1-RNP抗体。采用Kappa检验评估不同方法之间的一致性。采用受试者工作特征(ROC)曲线评估各项指标诊断AID的效能。结果AID组抗U1-RNP抗体和抗RNPA/RNP68抗体阳性率均高于非AID组和正常对照组(P<0.0167),非AID组2种抗体的阳性率亦高于正常对照组(P<0.0167)。各组抗U1-RNP抗体阳性率与抗RNPA/RNP68抗体阳性率差异无统计学意义(P>0.05)。正常对照组2种抗体的一致性较好(Kappa=0.92),AID组的一致性差(Kappa=0.10)。抗U1-RNP抗体、抗RNPA/RNP68抗体联合检测(2种抗体均阳性)诊断AID的曲线下面积(AUC)为0.80,高于单项检测(0.70、0.73)(P<0.01)。对于MCTD、SLE,抗U1-RNP抗体、抗RNPA/RNP68抗体联合检测的AUC分别为0.81、0.75,均高于抗U1-RNP抗体单项检测(AUC分别为0.73、0.70)(P<0.01);且2种抗体联合检测诊断SLE的AUC高于抗RNPA/RNP68抗体单项检测(0.67)(P<0.01)。对于狼疮性肾炎,抗U1-RNP抗体和抗RNPA/RNP68抗体联合检测的AUC为0.52,低于2种抗体单项检测的AUC(0.62、0.69)(P<0.05)。对于SS,抗RNPA/RNP68抗体单项检测的AUC为0.72,高于抗U1-RNP抗体单项检测(0.51)(P<0.05)。抗U1-RNP抗体、抗RNPA/RNP68抗体单项检测和联合检测诊断其他AID的AUC差异均无统计学意义(P>0.05)。结论抗U1-RNP抗体对诊断狼疮性肾炎、RNPA/RNP68抗体对诊断SS具有较高的效能;2种抗体联合检测可提高对SLE和MCTD的诊断效能。 展开更多
关键词 u1-核糖核蛋白抗体 抗RNPA/RNP68抗体 自身免疫性疾病
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PIM1基因对急性髓系白血病U937细胞增殖、凋亡及JAK2/STAT3信号通路的影响
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作者 高鑫 储李婧 颜宗海 《中国实验血液学杂志》 CAS CSCD 北大核心 2024年第3期663-669,共7页
目的:探讨PIM1基因对急性髓系白血病(AML)U937细胞增殖、凋亡的影响,以及对JAK2/STAT3通路的调控作用。方法:收集初诊成人AML患者和单纯缺铁性贫血患者的骨髓单个核细胞,荧光定量PCR检测PIM1 mRNA表达。将AML细胞系U937细胞分为:U937组(... 目的:探讨PIM1基因对急性髓系白血病(AML)U937细胞增殖、凋亡的影响,以及对JAK2/STAT3通路的调控作用。方法:收集初诊成人AML患者和单纯缺铁性贫血患者的骨髓单个核细胞,荧光定量PCR检测PIM1 mRNA表达。将AML细胞系U937细胞分为:U937组(U937细胞正常培养)、Si-PIM1组(U937细胞转染含PIM1 mRNA的低表达腺病毒载体)、Si-NC组(U937细胞转染不含PIM1 mRNA的低表达腺病毒载体)、CoA1组(U937细胞中加入浓度为20μmol/L的JAK2激活剂CoA1)、Si-PIM1+CoA1组(U937细胞转染含PIM1 mRNA低表达的腺病毒载体并加入浓度为20μmol/L的CoA1)。培养24 h。荧光定量PCR和蛋白印迹法检测U937细胞PIM1 mRNA和蛋白、JAK2/STAT3通路、细胞周期、凋亡相关蛋白表达;噻唑蓝法检测细胞增殖活性;流式细胞术检测细胞周期变化及凋亡率。结果:AML患者骨髓单个核细胞中PIM1 mRNA表达水平高于单纯缺铁性贫血患者(P<0.05)。与U937组相比,Si-PIM1组细胞PIM1 mRNA和蛋白、p-JAK2/JAK2、p-STAT3/STAT3、Cyclin D1、CDK2蛋白、细胞增殖活性、S期比例、G2/M期比例降低(均P<0.05),p27、Caspase-3蛋白、G0/G1期、凋亡率升高(均P<0.05),而CoA1组上述指标的变化情况与Si-PIM1组正好相反,CoA1可逆转Si-PIM1对U937细胞的作用效果。U937组、Si-PIM1+CoA1组、Si-NC组U937细胞上述指标差异无统计学意义(P>0.05)。结论:敲低PIM1基因表达可抑制U937细胞增殖、促进凋亡,缓解ALM进程,且上述作用可能与抑制JAK2/STAT3通路活化有关。 展开更多
关键词 丝/苏氨酸激酶家族成员1 急性髓系白血病u937细胞 增殖 凋亡 Janus酪氨酸激酶2/信号转导及转录激活因子3通路
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MEK1/2抑制剂U0126对射频消融术后残留肝癌细胞系HepG2-H作用的研究
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作者 贾辰昊 李彬 +3 位作者 李凤娟 柴虎林 凌海锋 贾国群 《内蒙古医学杂志》 2024年第9期1031-1034,1039,F0003,共6页
目的研究MEK1/2抑制剂U0126对肝癌射频消融术后残留肝癌细胞系HepG2-H的增殖、迁移和侵袭的影响。方法运用肝癌细胞系HepG2体外制作射频消融术后残留肝癌细胞系HepG2-H,通过细胞增殖、划痕、侵袭实验,观察实验组(加入10μmol/L、20μmo... 目的研究MEK1/2抑制剂U0126对肝癌射频消融术后残留肝癌细胞系HepG2-H的增殖、迁移和侵袭的影响。方法运用肝癌细胞系HepG2体外制作射频消融术后残留肝癌细胞系HepG2-H,通过细胞增殖、划痕、侵袭实验,观察实验组(加入10μmol/L、20μmol/L、30μmol/L的U0126)和对照组(不加入U0126)细胞的增殖、迁移和侵袭能力。结果实验组(加入10、20、30μmol/L的U0126)的吸光度值分别为:(0.6929±0.08257)、(0.5084±0.06012)、(0.4549±0.07660),对照组吸光度值为:(1.1245±0.07971);组间差异有统计学意义(P<0.05);实验组的迁移面积分别为:(5640.2±285.4)mm^(2)、(5082.4±237.7)mm^(2)、(4821.7±246.3)mm^(2),对照组的迁移面积为:(6053.8±269.2)mm^(2),组间差异有统计学意义(P<0.05);实验组的每高倍视野细胞计数分别为:(164.2±18.89)个、(138.4±18.06)个、(129.4±18.54)个,对照组的每高倍视野细胞计数为:(226.6±16.81)个,组间差异有统计学意义(P<0.05)。结论U0126可抑制射频消融术后残留肝癌细胞HepG2-H的增殖、迁移和侵袭。 展开更多
关键词 肝癌细胞 射频消融 MEK1/2 u0126
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一种(2SPU-1U)&1R少自由度帆船运动模拟平台的研究
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作者 陈龙 梁辉 +3 位作者 盛尉航 杨琳 邓芳 汪传生 《舰船电子工程》 2024年第5期88-93,共6页
针对现存多数单一自由度的帆船模拟运动平台,提出一种新型3-DOF的(2SPU-1U)&1R少自由度混联帆船运动模拟平台,该运动平台由一个2SPU-1U的并联机构和一个旋转副R串联构成,能够实现帆船的横摇、纵摇、艏摇三个自由度的运动模拟,同时... 针对现存多数单一自由度的帆船模拟运动平台,提出一种新型3-DOF的(2SPU-1U)&1R少自由度混联帆船运动模拟平台,该运动平台由一个2SPU-1U的并联机构和一个旋转副R串联构成,能够实现帆船的横摇、纵摇、艏摇三个自由度的运动模拟,同时该平台还可以应用到驾驶、飞行等模拟器场合。采用Grübler-Kutzbach公式计算出机构的自由度数目,建立了2SPU-1U并联机构的约束方程,并通过数值法求解出并联机构的位姿逆解,利用粒子群优化(PSO)算法分析并联机构的位姿正解。最后运用Solidworks和Adams软件进行联合建模仿真分析,验证了机构运行平稳,能够实现帆船横摇、纵摇和艏摇的运动模拟。 展开更多
关键词 2SPu-1u 少自由度 混联机构 ADAMS仿真
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Cr和Si含量对重载铁路用75 kg·m^(-1)U77MnCrH钢轨组织与性能的影响
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作者 金纪勇 王冬 +3 位作者 于海鑫 桂林 张瑜 刘丰收 《中国铁道科学》 EI CAS CSCD 北大核心 2024年第5期13-21,共9页
为开发适应重载铁路用高强韧、高硬度耐磨钢轨,按照C-Si-Mn-Cr成分设计体系进行U77MnCrH钢轨钢的成分设计和中试试验;基于中试试验的组织性能,筛选出组织性能较好的试验钢进行75 kg·m^(-1)U77MnCrH钢轨试制试验;使用金相显微镜、... 为开发适应重载铁路用高强韧、高硬度耐磨钢轨,按照C-Si-Mn-Cr成分设计体系进行U77MnCrH钢轨钢的成分设计和中试试验;基于中试试验的组织性能,筛选出组织性能较好的试验钢进行75 kg·m^(-1)U77MnCrH钢轨试制试验;使用金相显微镜、场发射扫描电子显微镜、透射电子显微镜、万能拉伸试验机及硬度计对75 kg·m^(-1)U77MnCrH钢轨试样进行组织性能分析。结果表明:随着Cr含量由0.26%增加到0.38%,钢轨钢试样中珠光体片层间距由165 nm减小到146 nm,抗拉强度和硬度均有提高,屈服强度R_(p0.2)与断后伸长率均有降低;随着Si含量由0.25%增加到0.45%,珠光体片层间距由165 nm减小到132 nm,断后伸长率和硬度均有提高,屈服强度R_(p0.2)明显增加,抗拉强度变化不大;0.45%的Si配合0.26%的Cr获得的钢轨珠光体更加均匀细小,片层间距分布更加均匀,力学性能与硬度匹配更好,抗拉强度达到1258 MPa,屈服强度R_(p0.2)达到845 MPa,断后伸长率达到13.0%,轨头顶面硬度达384 HBW,横断面硬度介于36.2~38.8 HRC。75 kg·m^(-1)U77MnCrH钢轨的各项指标对生产实践具有较强的参考价值。 展开更多
关键词 重载铁路 75 kg·m^(-1)u77MnCrH钢轨 透射电子显微镜 万能拉伸试验机 珠光体
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雷公藤甲素通过miR-34b-5p/Notch1轴抑制骨肉瘤U2OS细胞增殖并诱导其铁死亡 被引量:1
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作者 姜福贵 伍俊峰 +2 位作者 杨标 吴中恒 周平 《中国肿瘤生物治疗杂志》 CAS CSCD 北大核心 2024年第6期579-585,共7页
目的:探究雷公藤甲素(TPL)通过miR-34b-5p调控Notch1表达对骨肉瘤U2OS细胞铁死亡影响的机制。方法:常规培养U2OS细胞,将其分为对照组、TPL(10μmol/L)组、TPL(10μmol/L)+Fer-1(铁死亡抑制剂,20μmol/L)组、miR-NC组、miR-34b-5p组、miR... 目的:探究雷公藤甲素(TPL)通过miR-34b-5p调控Notch1表达对骨肉瘤U2OS细胞铁死亡影响的机制。方法:常规培养U2OS细胞,将其分为对照组、TPL(10μmol/L)组、TPL(10μmol/L)+Fer-1(铁死亡抑制剂,20μmol/L)组、miR-NC组、miR-34b-5p组、miR-34b-5p+Fer-1(20μmol/L)组、TPL(10μmol/L)+anti-miR-34b-5p组、anti-miR-34b-5p+Fer-1(20μmol/L)组。qPCR法、CCK-8法、铁离子检测试剂、DHE-荧光探针和WB法分别检测各组U2OS细胞中miR-34b-5p的表达、增殖能力、Fe2+水平、ROS水平以及铁死亡相关蛋白(GPX4、SLC7A11及Notch1蛋白)的表达,双萤光素酶报告基因实验验证miR-34b-5p与Notch1的靶向结合关系。结果:TPL可促进U2OS细胞中miR-34b-5p表达,Fer-1和anti-miR-34b-5p则抑制miR-34b-5p的表达(均P<0.05)。TPL明显抑制U2OS细胞的增殖、GPX4、SLC7A11、Notch1蛋白的表达、增加细胞中Fe2+和ROS的含量,Fer-1可逆转TPL对U2OS细胞的作用(均P<0.05)。过表达miR-34b-5p与TPL对U2OS细胞的作用相似(均P<0.05)。miR-34b-5p可靶向结合Notch1(均P<0.05)。miR-34b-5p抑制剂可明显抑制TPL对U2OS细胞的影响,Fer-1可增强miR-34b-5p抑制剂的作用(均P<0.05)。结论:TPL可抑制U2OS细胞的增殖能力并促进其铁死亡,其作用机制可能与miR-34a-5p靶向调节Notch1表达有关。 展开更多
关键词 雷公藤甲素 骨肉瘤 u2OS细胞 miR-34b-5p NOTCH1 铁死亡
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κ‑阿片受体激动剂U50488H通过抑制NLRP3/Caspase‑1信号通路对体外循环致大鼠肺损伤的影响 被引量:1
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作者 刘晓洋 高光洁 《实用药物与临床》 CAS 2024年第7期488-492,共5页
目的观察κ-阿片受体(KOR)激动剂U50488H对体外循环诱导的大鼠肺损伤的影响,并探讨U50488H对肺保护的作用机制。方法将24只SPF级SD大鼠随机分为假手术组(Sham组)、大鼠体外循环模型组(CPB组)和KOR激动剂在体外循环(CPB)模型中的干预组(U... 目的观察κ-阿片受体(KOR)激动剂U50488H对体外循环诱导的大鼠肺损伤的影响,并探讨U50488H对肺保护的作用机制。方法将24只SPF级SD大鼠随机分为假手术组(Sham组)、大鼠体外循环模型组(CPB组)和KOR激动剂在体外循环(CPB)模型中的干预组(U50448H组),每组8只。U50448H组于CPB前30 min静脉注射1.5 mg/kg U50488H,分别于CPB后0 h、1 h和2 h各时点行动脉血气分析,计算肺泡-动脉氧分压差(AaDO_(2))和呼吸指数(Respiratory index,RI)。三组大鼠均在停CPB后2 h时处死,取完整右肺下叶,采用重力法测定血管外肺水(Extravascular lung water,EVLW),HE染色观察肺组织形态学变化。采用ELISA方法检测血浆脂多糖(LPS)、超氧化物歧化酶(SOD)、丙二醛(MDA)和还原型谷胱甘肽(GSH)的含量,TUNEL法检测肺组织的细胞凋亡,Western blot测定肺组织GSDMD-C、GSDMD-N、NLRP3、ASC、pro-Caspase-1和pro-IL-1β蛋白的表达。结果CPB组大鼠在CPB后0 h、1 h和2 h各时点的AaDO_(2)和RI、LPS明显高于Sham组(P<0.05);U50488H组3个时点的AaDO_(2)、RI、LPS均明显低于CPB组(P<0.05)。与Sham组比较,CPB组大鼠EVLW,血浆MDA和GSH,肺组织的凋亡指数(AI),NLRP3、ASC、pro-Caspase-1和pro-IL-1β蛋白的表达明显增高,血浆SOD含量明显降低,差异均有统计学意义(P<0.05);而U50488H组上述指标与Sham组比较,差异无统计学意义(P>0.05)。CPB组大鼠出现了严重的肺损伤和肺泡内充血/出血,并伴有广泛的炎症细胞浸润,U50448H组肺损伤明显减轻。结论κ-阿片受体激动剂U50488H通过抑制肺组织中NLRP3/Caspase-1信号通路介导的炎症和氧化应激反应,从而减轻CPB后大鼠的肺损伤。 展开更多
关键词 κ-阿片受体激动剂 u50488H 体外循环 急性肺损伤 NLRP3/Caspase-1
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肝细胞癌患者癌组织中CRIP1、STUB1表达及临床预后意义
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作者 张景 沈晨 +1 位作者 马鹏飞 郑幼伟 《国际检验医学杂志》 CAS 2024年第3期266-271,共6页
目的探讨肝细胞癌患者癌组织中富含半胱氨酸肠蛋白1(CRIP1)、STIP1同源性和包含U-box蛋白1(STUB1)表达及临床预后意义。方法选取2018年2月至2020年2月该院诊治的112例肝细胞癌患者作为研究对象。免疫组化法检测肝细胞癌患者癌组织和癌... 目的探讨肝细胞癌患者癌组织中富含半胱氨酸肠蛋白1(CRIP1)、STIP1同源性和包含U-box蛋白1(STUB1)表达及临床预后意义。方法选取2018年2月至2020年2月该院诊治的112例肝细胞癌患者作为研究对象。免疫组化法检测肝细胞癌患者癌组织和癌旁组织中CRIP1、STUB1表达。分析肝细胞癌患者癌组织CRIP1、STUB1表达与其临床病理特征的关系。Kaplan-Meier生存分析癌组织CRIP1、STUB1表达对肝细胞癌患者预后的影响。COX回归分析影响肝细胞癌预后的因素。结果肝细胞癌患者癌组织中CRIP1阳性率为62.50%(70/112),明显高于癌旁组织[7.14%(8/112)],差异有统计学意义(χ^(2)=76.652,P<0.05)。肝细胞癌患者癌组织中STUB1阳性率为26.23%(32/112),明显低于癌旁组织[82.14%(92/112)],差异有统计学意义(χ^(2)=73.284,P<0.05)。癌组织中CRIP1与STUB1表达呈负相关(r=-0.678,P<0.001)。不同肿瘤TNM分期、组织学分级及肿瘤最大径的肝细胞癌患者癌组织中CRIP1、STUB1阳性率比较,差异有统计学意义(P<0.05)。CRIP1阳性组3年累积生存率明显低于CRIP1阴性组,差异有统计学意义(Log-rankχ^(2)=29.601,P<0.001)。STUB1阴性组3年累积生存率明显低于STUB1阳性组,差异有统计学意义(Log-rankχ^(2)=13.590,P<0.001)。肿瘤TNM分期Ⅱ~Ⅲ期、组织学分级Ⅲ级、肿瘤最大径>5 cm、CRIP1阳性、STUB1阴性是影响肝细胞癌患者预后的独立危险因素。结论肝细胞癌患者癌组织中CRIP1表达上调,STUB1表达下调,临床上可根据肝细胞癌患者癌组织中CRIP1、STUB1表达情况对患者预后进行评估。 展开更多
关键词 肝细胞癌 富含半胱氨酸肠蛋白1 STIP1同源性和包含u-box蛋白1 临床病理特征 预后
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Nonlocal symmetry and exact solutions of the(2+1)-dimensional modified Bogoyavlenskii–Schiff equation 被引量:3
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作者 黄丽丽 陈勇 《Chinese Physics B》 SCIE EI CAS CSCD 2016年第6期63-70,共8页
In this paper,the truncated Painlev′e analysis,nonlocal symmetry,Bcklund transformation of the(2+1)-dimensional modified Bogoyavlenskii–Schiff equation are presented.Then the nonlocal symmetry is localized to the... In this paper,the truncated Painlev′e analysis,nonlocal symmetry,Bcklund transformation of the(2+1)-dimensional modified Bogoyavlenskii–Schiff equation are presented.Then the nonlocal symmetry is localized to the corresponding nonlocal group by the prolonged system.In addition,the(2+1)-dimensional modified Bogoyavlenskii–Schiff is proved consistent Riccati expansion(CRE) solvable.As a result,the soliton–cnoidal wave interaction solutions of the equation are explicitly given,which are difficult to find by other traditional methods.Moreover figures are given out to show the properties of the explicit analytic interaction solutions. 展开更多
关键词 (2+1)-dimensional modified Bogoyavlenskii–Schiff equation nonlocal symmetry consistent Riccati expansion soliton–cnoidal wave solution
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Symmetry Groups and New Exact Solutions to (2+1)-Dimensional Variable Coefficient Canonical Generalized KP Equation 被引量:7
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作者 ZHANG Li-Hua LIU Xi-Qiang BAI Cheng-Lin 《Communications in Theoretical Physics》 SCIE CAS CSCD 2007年第3X期405-410,共6页
In this paper, the modified CK's direct method to find symmetry groups of nonlinear partial differential equation is extended to (2+1)-dimensional variable coeffficient canonical generalized KP (VCCGKP) equation... In this paper, the modified CK's direct method to find symmetry groups of nonlinear partial differential equation is extended to (2+1)-dimensional variable coeffficient canonical generalized KP (VCCGKP) equation. As a result, symmetry groups, Lie point symmetry group and Lie symmetry for the VCCGKP equation are obtained. In fact, the Lie point symmetry group coincides with that obtained by the standard Lie group approach. Applying the given Lie symmetry, we obtain five types of similarity reductions and a lot of new exact solutions, including hyperbolic function solutions, triangular periodic solutions, Jacobi elliptic function solutions and rational solutions, for the VCCGKP equation. 展开更多
关键词 (2+1)-dimensional variable coefficient canonical generalized KP (VCCGKP) equation modified CK's'direct method symmetry groups Lie symmetry similarity reductions new exact solutions
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Extended symmetry transformation of (3+1)-dimensional generalized nonlinear Schrdinger equation with variable coefficients 被引量:1
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作者 荆建春 李彪 《Chinese Physics B》 SCIE EI CAS CSCD 2013年第1期77-83,共7页
In this paper, the extended symmetry transformation of (3+1)-dimensional (3D) generalized nonlinear Schrodinger (NLS) equations with variable coefficients is investigated by using the extended symmetry approach... In this paper, the extended symmetry transformation of (3+1)-dimensional (3D) generalized nonlinear Schrodinger (NLS) equations with variable coefficients is investigated by using the extended symmetry approach and symbolic computation. Then based on the extended symmetry, some 3D variable coefficient NLS equations are reduced to other variable coefficient NLS equations or the constant coefficient 3D NLS equation. By using these symmetry transformations, abundant exact solutions of some 3D NLS equations with distributed dispersion, nonlinearity, and gain or loss are obtained from the constant coefficient 3D NLS equation. 展开更多
关键词 (3+1)-dimensional nonlinear Schrodinger equation extended symmetry exact solution symbolic computation
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Symmetry analysis and explicit solutions of the (3+1)-dimensional baroclinic potential vorticity equation 被引量:1
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作者 胡晓瑞 陈勇 黄菲 《Chinese Physics B》 SCIE EI CAS CSCD 2010年第8期35-45,共11页
This paper investigates an important high-dimensional model in the atmospheric and oceanic dynamics-(3+1)- dimensional nonlinear baroclinic potential vorticity equation by the classical Lie group method. Its symmet... This paper investigates an important high-dimensional model in the atmospheric and oceanic dynamics-(3+1)- dimensional nonlinear baroclinic potential vorticity equation by the classical Lie group method. Its symmetry algebra, symmetry group and group-invariant solutions are analysed. Otherwise, some exact explicit solutions are obtained from the corresponding (2+1)-dimensional equation, the inviscid barotropic nondivergent vorticy equation. To show the properties and characters of these solutions, some plots as well as their possible physical meanings of the atmospheric circulation are given out. 展开更多
关键词 (3+1)-dimensional nonlinear baroclinic potential vorticity equation symmetry group group-invariant solution explicit solution
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Lie Symmetry Groups of(2+1)-Dimensional BKP Equation and Its New Solutions 被引量:1
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作者 MA Hong-Cai LOU Sen-Yue DENG Ai-Ping 《Communications in Theoretical Physics》 SCIE CAS CSCD 2008年第9期685-688,共4页
A modified direct method is developed to find finite symmetry groups of nonlinear mathematical physicssystems.Applying the modified direct method to the well-known (2+1)-dimensional BKP equation we get its symmetry.Fu... A modified direct method is developed to find finite symmetry groups of nonlinear mathematical physicssystems.Applying the modified direct method to the well-known (2+1)-dimensional BKP equation we get its symmetry.Furthermore,the exact solutions of (2+1)-dimensional BKP equation are obtained through symmetry analysis. 展开更多
关键词 (2+1)-dimensional BKP equation Lie symmetry group CK's direct method exact solution
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Spontaneous U(1) symmetry breaking and Bose-Einstein condensation
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作者 钱锋 黄洪斌 +1 位作者 齐观晓 沈才康 《Chinese Physics B》 SCIE EI CAS CSCD 2006年第7期1577-1579,共3页
Based on Bogoliubov's truncated Hamiltonian HB for a weakly interacting Bose system, and adding a U(1) symmetry breaking term √V(λα0+λα0^+) to HB, we show by using the coherent state theory and the mean-fi... Based on Bogoliubov's truncated Hamiltonian HB for a weakly interacting Bose system, and adding a U(1) symmetry breaking term √V(λα0+λα0^+) to HB, we show by using the coherent state theory and the mean-field approximation rather than the c-number approximations, that the Bose-Einstein condensation(BEC) occurs if and only if the U(1) symmetry of the system is spontaneously broken. The real ground state energy and the justification of the Bogoliubov c-number substitution are given by solving the Schroedinger eigenvalue equation and using the self-consistent condition. 展开更多
关键词 BEC u1 symmetry breaking generalized Su1 1 coherent state
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Degenerate States in Nonlinear Sigma Model with U(1) Symmetry<br/><br/><sub>—For Study on Violation of Cluster Property</sub>
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作者 Tomo Munehisa 《World Journal of Condensed Matter Physics》 CAS 2021年第3期29-52,共24页
Entanglement in quantum theory is a concept that has confused many scientists. This concept implies that the cluster property, which means no relations between sufficiently separated two events, is non-trivial. In the... Entanglement in quantum theory is a concept that has confused many scientists. This concept implies that the cluster property, which means no relations between sufficiently separated two events, is non-trivial. In the works for some quantum spin systems, which have been recently published by the author, extensive and quantitative examinations were made about the violation of cluster property in the correlation function of the spin operator. The previous study of these quantum antiferromagnets showed that this violation is induced by the degenerate states in the systems where the continuous symmetry spontaneously breaks. Since this breaking is found in many materials such as the high temperature superconductors and the superfluidity, it is an important question whether we can observe the violation of the cluster property in them. As a step to answer this question we study a quantum nonlinear sigma model with U(1) symmetry in this paper. It is well known that this model, which has been derived as an effective model of the quantum spin systems, can also be applied to investigations of many materials. Notifying that the existence of the degenerate states is essential for the violation, we made numerical calculations in addition to theoretical arguments to find these states in the nonlinear sigma model. Then, successfully finding the degenerate states in the model, we came to a conclusion that there is a chance to observe the violation of cluster property in many materials to which the nonlinear sigma model applies. 展开更多
关键词 Quantum Nonlinear Sigma Model u(1) symmetry Cluster Property Spontaneous symmetry Breaking Degenerate States
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Truncated series solutions to the(2+1)-dimensional perturbed Boussinesq equation by using the approximate symmetry method
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作者 Xiao-Yu Jiao 《Chinese Physics B》 SCIE EI CAS CSCD 2018年第10期123-129,共7页
In this paper, the(2+1)-dimensional perturbed Boussinesq equation is transformed into a series of two-dimensional(2 D) similarity reduction equations by using the approximate symmetry method. A step-by-step proce... In this paper, the(2+1)-dimensional perturbed Boussinesq equation is transformed into a series of two-dimensional(2 D) similarity reduction equations by using the approximate symmetry method. A step-by-step procedure is used to acquire Jacobi elliptic function solutions to these similarity equations, which generate the truncated series solutions to the original perturbed Boussinesq equation. Aside from some singular area, the series solutions are convergent when the perturbation parameter is diminished. 展开更多
关键词 approximate symmetry method (2+1)-dimensional perturbed Boussinesq equation series solutions convergence of series solutions
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Spontaneous U(1) Symmetry Breaking in Coupled Bose System
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作者 王影 徐金荣 +1 位作者 陈理 刘果红 《Communications in Theoretical Physics》 SCIE CAS CSCD 2011年第6期997-1000,共4页
Adding a U(1) symmetry breaking term √V(λ1a0 + λ1*a0) + √V(λ2b0 + λ2*b0) to Bogoliubov's truncated Hamiltonian HB for a weakly interacting coupled Bose system, by using the mean-field approximation r... Adding a U(1) symmetry breaking term √V(λ1a0 + λ1*a0) + √V(λ2b0 + λ2*b0) to Bogoliubov's truncated Hamiltonian HB for a weakly interacting coupled Bose system, by using the mean-field approximation rather than the c-number approximation, we And that, via a Feshbach resonance at zero temperature, the states of the coupled Bose system are generalized SU(1,1) SU(1,1) coherent states. The Bose-Einstein condensation occurs in response to the spontaneous U(1) symmetry breaking. 展开更多
关键词 BEC u1 symmetry breaking generalized Su1 1 Su1 1 coherent state Feshbach resonance
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塔里木马鹿CP2U1基因真核表达载体的构建及其生物信息学分析
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作者 布威海丽且姆·阿巴拜科日 布海力切木·依明艾力 +1 位作者 米合热古丽·库尔班 克热木江·阿布都热合曼 《农业灾害研究》 2024年第9期37-39,42,共4页
为了分析塔里木马鹿(Cervus elaphus yarkandensis)细胞色素P450 2U1(CP2U1)基因的结构和相关功能,利用RTPCR方法获取塔里木马鹿CP2U1基因288 bp的CDS序列,并构建其真核表达载体pcDNA3.1(+)-CeyCP2U1。生物信息学分析结果表明:该基因能... 为了分析塔里木马鹿(Cervus elaphus yarkandensis)细胞色素P450 2U1(CP2U1)基因的结构和相关功能,利用RTPCR方法获取塔里木马鹿CP2U1基因288 bp的CDS序列,并构建其真核表达载体pcDNA3.1(+)-CeyCP2U1。生物信息学分析结果表明:该基因能编码95个氨基酸,氨基酸组分中没有天冬酰胺;其蛋白为疏水性、不稳定蛋白,没有跨膜区、信号肽、N-糖基化位点和O-糖基化位点,但具有8个潜在的磷酸化位点;塔里木马鹿CP2U1与东欧马鹿和白尾鹿的相似性最高,而与褐家鼠的同源性最低.;CP2U1蛋白在适应极端干旱环境中发挥潜在的作用。 展开更多
关键词 塔里木马鹿 CP2u1基因 生物信息学分析
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Revisions of P-1 Space Groups to Higher Symmetry Space Groups
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作者 胡盛志 伍锡荣 《Chinese Journal of Structural Chemistry》 SCIE CAS CSCD 2014年第1期148-164,共17页
The space groups of 244 crystal structures originally reported as P-1 are revised to space groups of higher symmetry. The largest number involves revisions to P2/c and C2/c.
关键词 CL Revisions of P-1 Space Groups to Higher symmetry Space Groups Ru THAN Ni Cu Si Co
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Painlevé property, local and nonlocal symmetries, and symmetry reductions for a (2+1)-dimensional integrable KdV equation
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作者 Xiao-Bo Wang Man Jia Sen-Yue Lou 《Chinese Physics B》 SCIE EI CAS CSCD 2021年第1期178-184,共7页
The Painlevé property for a(2+1)-dimensional Korteweg–de Vries(KdV) extension, the combined KP3(Kadomtsev–Petviashvili) and KP4(cKP3-4), is proved by using Kruskal’s simplification. The truncated Painlevé... The Painlevé property for a(2+1)-dimensional Korteweg–de Vries(KdV) extension, the combined KP3(Kadomtsev–Petviashvili) and KP4(cKP3-4), is proved by using Kruskal’s simplification. The truncated Painlevé expansion is used to find the Schwartz form, the Bäcklund/Levi transformations, and the residual nonlocal symmetry. The residual symmetry is localized to find its finite Bäcklund transformation. The local point symmetries of the model constitute a centerless Kac–Moody–Virasoro algebra. The local point symmetries are used to find the related group-invariant reductions including a new Lax integrable model with a fourth-order spectral problem. The finite transformation theorem or the Lie point symmetry group is obtained by using a direct method. 展开更多
关键词 Painlevéproperty residual symmetry Schwartz form Bäcklund transforms D’Alembert waves symmetry reductions Kac–Moody–Virasoro algebra (2%PLuS%1)-dimensional KdV equation
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