In their study,association of daily sitting time and leisure-time physical activity (LTPA) with body fat among U.S.Adults,Liao et al.^(1) analyzed data from the 2011-2018 National Health and Examination Survey to exam...In their study,association of daily sitting time and leisure-time physical activity (LTPA) with body fat among U.S.Adults,Liao et al.^(1) analyzed data from the 2011-2018 National Health and Examination Survey to examine associations between h/day sitting,meeting (or not meeting) the U.S.Physical Activity Guidelines of≥150 min/week of moderate-and vigorous-intensity LTPA,and combinations of sitting time and LTPA on totaland trunk percent body fat (BF%).展开更多
With the rapidly aging human population,age-related cognitive decline and dementia are becoming increasingly prevalent worldwide.Aging is considered the main risk factor for cognitive decline and acts through alterati...With the rapidly aging human population,age-related cognitive decline and dementia are becoming increasingly prevalent worldwide.Aging is considered the main risk factor for cognitive decline and acts through alterations in the composition of the gut microbiota,microbial metabolites,and the functions of astrocytes.The microbiota–gut–brain axis has been the focus of multiple studies and is closely associated with cognitive function.This article provides a comprehensive review of the specific changes that occur in the composition of the gut microbiota and microbial metabolites in older individuals and discusses how the aging of astrocytes and reactive astrocytosis are closely related to age-related cognitive decline and neurodegenerative diseases.This article also summarizes the gut microbiota components that affect astrocyte function,mainly through the vagus nerve,immune responses,circadian rhythms,and microbial metabolites.Finally,this article summarizes the mechanism by which the gut microbiota–astrocyte axis plays a role in Alzheimer’s and Parkinson’s diseases.Our findings have revealed the critical role of the microbiota–astrocyte axis in age-related cognitive decline,aiding in a deeper understanding of potential gut microbiome-based adjuvant therapy strategies for this condition.展开更多
Since the beginning of the 21st century,major earthquakes have frequently occurred worldwide.To explore the impact of astronomical factors on earthquakes,in this study,the statistical analysis method of correlation is...Since the beginning of the 21st century,major earthquakes have frequently occurred worldwide.To explore the impact of astronomical factors on earthquakes,in this study,the statistical analysis method of correlation is used to systematically analyze the effects of astronomical factors,such as solar activity,Earth’s rotation,lunar declination angle,celestial tidal force,and other phenomena on M≥8 global earthquakes at the beginning of the 21st century.With regard to solar activity,this study focuses on the analysis of the 11-year and century cycles of solar activity.The causal relationship of the Earth’s rotation is not obvious in this work and previous works;in contrast,the valley period of the solar activity century cycle may be an important astronomical factor leading to the frequent occurrence of global earthquakes at the beginning of the 21st century.This topic warrants further study.展开更多
On January 5,the Chinese People's Association for Friendship with Foreign Countries and the Chinese People's Institute of Foreign Affairs jointly hosted a reception commemorating the 45th anniversary of the es...On January 5,the Chinese People's Association for Friendship with Foreign Countries and the Chinese People's Institute of Foreign Affairs jointly hosted a reception commemorating the 45th anniversary of the establishment of diplomatic relationship between China and the United States in Beijing.Member of the Political Bureau of the CPC Central Committee and Foreign Minister Wang Yi attended the commemoration and delivered aspeech.David Meale,ChargédAffaires at the U.S.Embassy in China,addressed the reception.He extended on behalf of the U.S.side congratulations on the anniversary,expressing the readiness of the U.S.to implement the consensus reached by the two heads of state and promote the steady development of U.S.-China relations.More than 350 people from all walks of life of both countries attended the reception.展开更多
The 100 men and women who make up the U.S.Senate will soon have an important choice.They will either affirm that the First Amendment matters or they will surrender to fear.The senators must decide whether to go along ...The 100 men and women who make up the U.S.Senate will soon have an important choice.They will either affirm that the First Amendment matters or they will surrender to fear.The senators must decide whether to go along with their colleagues in the House of Representatives and require the popular social media app TikTok to be sold to an American company.If they do endorse the House vote,then ByteDance must divest itself of TikTok or see the app will be banned on U.S.-based social media platforms.展开更多
文摘In their study,association of daily sitting time and leisure-time physical activity (LTPA) with body fat among U.S.Adults,Liao et al.^(1) analyzed data from the 2011-2018 National Health and Examination Survey to examine associations between h/day sitting,meeting (or not meeting) the U.S.Physical Activity Guidelines of≥150 min/week of moderate-and vigorous-intensity LTPA,and combinations of sitting time and LTPA on totaland trunk percent body fat (BF%).
基金supported by the Haihe Laboratory of Cell Ecosystem Innovation Foundation,No.22HHXBSS00047(to PL)Graduate Science and Technology Innovation Project of Tianjin,No.2022BKY173(to LZ)Tianjin Municipal Science and Technology Bureau Foundation,No.20201194(to PL).
文摘With the rapidly aging human population,age-related cognitive decline and dementia are becoming increasingly prevalent worldwide.Aging is considered the main risk factor for cognitive decline and acts through alterations in the composition of the gut microbiota,microbial metabolites,and the functions of astrocytes.The microbiota–gut–brain axis has been the focus of multiple studies and is closely associated with cognitive function.This article provides a comprehensive review of the specific changes that occur in the composition of the gut microbiota and microbial metabolites in older individuals and discusses how the aging of astrocytes and reactive astrocytosis are closely related to age-related cognitive decline and neurodegenerative diseases.This article also summarizes the gut microbiota components that affect astrocyte function,mainly through the vagus nerve,immune responses,circadian rhythms,and microbial metabolites.Finally,this article summarizes the mechanism by which the gut microbiota–astrocyte axis plays a role in Alzheimer’s and Parkinson’s diseases.Our findings have revealed the critical role of the microbiota–astrocyte axis in age-related cognitive decline,aiding in a deeper understanding of potential gut microbiome-based adjuvant therapy strategies for this condition.
文摘Since the beginning of the 21st century,major earthquakes have frequently occurred worldwide.To explore the impact of astronomical factors on earthquakes,in this study,the statistical analysis method of correlation is used to systematically analyze the effects of astronomical factors,such as solar activity,Earth’s rotation,lunar declination angle,celestial tidal force,and other phenomena on M≥8 global earthquakes at the beginning of the 21st century.With regard to solar activity,this study focuses on the analysis of the 11-year and century cycles of solar activity.The causal relationship of the Earth’s rotation is not obvious in this work and previous works;in contrast,the valley period of the solar activity century cycle may be an important astronomical factor leading to the frequent occurrence of global earthquakes at the beginning of the 21st century.This topic warrants further study.
文摘On January 5,the Chinese People's Association for Friendship with Foreign Countries and the Chinese People's Institute of Foreign Affairs jointly hosted a reception commemorating the 45th anniversary of the establishment of diplomatic relationship between China and the United States in Beijing.Member of the Political Bureau of the CPC Central Committee and Foreign Minister Wang Yi attended the commemoration and delivered aspeech.David Meale,ChargédAffaires at the U.S.Embassy in China,addressed the reception.He extended on behalf of the U.S.side congratulations on the anniversary,expressing the readiness of the U.S.to implement the consensus reached by the two heads of state and promote the steady development of U.S.-China relations.More than 350 people from all walks of life of both countries attended the reception.
文摘The 100 men and women who make up the U.S.Senate will soon have an important choice.They will either affirm that the First Amendment matters or they will surrender to fear.The senators must decide whether to go along with their colleagues in the House of Representatives and require the popular social media app TikTok to be sold to an American company.If they do endorse the House vote,then ByteDance must divest itself of TikTok or see the app will be banned on U.S.-based social media platforms.
