The Role of Consciousness in Healing Therapies: A Brief History of Ancestral Energies, Biofield and Ultra-Weak Photon Emission

Healing therapies are a set of techniques used with the aim of transfusing healthy “bioenergy” to other people in order to restore physical, mental, and emotional balance. It is necessary that something is donated from the healer, that is, something results from his organic metabolism. Also, based on your physical, mental, and emotional health, the energy resulting from your metabolism is assumed to be healthy for the healing of patients. On the other hand, also in many cases, healing does not occur due to the “vicious” quality of the energy to be transfused and the low receptivity of the patient. However, in most cases, it depends not only on the healer but also on the receiver, but usually on other healers, such as higher order consciousnesses. In fact, in many cases of healing, the effect is almost instantaneous with just the healer’s “magnetic energy”, especially in painful crises. Without a doubt, I believe that biophoton is an anti-inflammatory, analgesic, antibacterial and immunomodulatory bioenergy. The healing effectiveness of these therapies is well established. It is a cell-restoring product that can rebuild tissues and organs in a short time, which in many cases leads to the restoration of the patient’s health and well-being. The aim of this study is to address a brief history of ancestral energies of Asian philosophy (Chinese, Japanese and Indian), highlight the role of consciousness and the healer in healing therapies. In addition, the study emphasizes the similarity of these energies with the one called “ectoplasm”, as well as it establishes connections with the newly elected ultra-weak emission of photons. Finally, bibliographic research was carried out in an English language database and innovative concepts were introduced about the role of consciousness as well as the healer in healing therapies.

Traditional Chinese Medicine-Based Subtyping of Early-Stage Type 2 Diabetes Using Plasma Metabolomics Combined with Ultra-Weak Photon Emission

The prevalence of type 2 diabetes mellitus(T2DM)is increasing rapidly worldwide.Because of the limited success of generic interventions,the focus of the disease study has shifted toward personalized strategies,particularly in the early stages of the disease.Traditional Chinese medicine(TCM)is based on a systems view combined with personalized strategies and has improved our knowledge of personalized diagnostics.From a systems biology perspective,the understanding of personalized diagnostics can be improved to yield a biochemical basis for such strategies;for example,metabolomics can be used in combination with other system-based diagnostic methods such as ultra-weak photon emission(UPE).In this study,we investigated the feasibility of using plasma metabolomics obtained from 44 pre-T2DM subjects to stratify the following TCM-based subtypes:Qi-Yin deficiency,Qi-Yin deficiency with dampness,and Qi-Yin deficiency with stagnation.We studied the relationship between plasma metabolomics and UPE with respect to TCM-based subtyping in order to obtain biochemical information for further interpreting disease subtypes.Principal component analysis of plasma metabolites revealed differences among the TCM-based pre-T2DM subtypes.Relatively high levels of lipids(e.g.,cholesterol esters and triglycerides)were important discriminators of two of the three subtypes and may be associated with a higher risk of cardiovascular disease.Plasma metabolomics data indicate that the lipid profile is an essential component captured by UPE with respect to stratifying subtypes of T2DM.The results suggest that metabolic differences exist among different TCM-based subtypes of pre-T2DM,and profiling plasma metabolites can be used to discriminate among these subtypes.Plasma metabolomics thus provides biochemical insights into system-based UPE measurements.

Technetium-99m-methylene diphosphonate single photon emission computed tomography/computed tomography combined with prostate-specific antigen/free prostate-specific antigen ratio for bone metastasis of prostate cancer

BACKGROUND Prostate cancer(PC)is one of the most common malignant tumors in men,and bone metastasis is one of its common complications,which seriously affects the quality of life and prognosis of patients.AIM To investigate the diagnostic value of technetium-99m-methylene diphosphonate(99mTc-MDP)single photon emission computed tomography(SPECT)/CT imaging combined with the serum prostate-specific antigen(PSA)/free PSA ratio for PC bone metastasis(PCBM).METHODS One hundred patients with PC who visited the Hospital of Chengdu University of Traditional Chinese Medicine from January 2020 to January 2022 were recruited as the experimental(Exp)group,while 30 patients with benign prostatic lesions(BPLs)were recruited as the control(Ctrl)group.All patients underwent 99mTc-MDP SPECT/CT imaging and serum PSA/fPSA testing.The SPECT/CT imaging results and serum PSA/fPSA ratios of patients were analyzed to evaluate their diagnostic values for PCBM.RESULTS The difference in general information of the patients was not obvious,showing comparability.The two methods showed no visible differences in negative predictive value and sensitivity for patients with PCBM,but had great differences in positive predictive value and specificity(P<0.05).The PSA/fPSA ratio of patients with PC in the Exp group was lower than those with BPLs,and patients with PCBM had a much lower PSA/fPSA ratio than those without PC(P<0.05).The results confirmed that the combined use of 99mTc-MDP SPECT/CT imaging and serum PSA/fPSA ratio achieved a detection rate of 95%for PCBM.CONCLUSION The combination of 99mTc-MDP SPECT/CT and PSA/fPSA ratio is accurate and reliable for the diagnosis of PCBM,which provides an important reference for clinical practice.

Spontaneous emission fromΛ-type three-level atom driven by bichromatic field in anisotropic double-band photonic crystals

The spontaneous emission property ofΛ-type three-level atom driven by the bichromatic field in the anisotropic double-band photonic crystal is calculated by n-times iteration method.The influence of different parameters on atomic spontaneous emission is studied,and the phenomena of atomic spontaneous emission are explained in the dressed state representation.It is found that the spontaneous emission spectra of the atom driven by the bichromatic field presents a multi-peak comb structure.The position of the emission peak is determined by the initial state of the atom,and the interval between the neighboring emission peaks is the detuningδof the bichromatic field.When the ratio between Rabi frequency intensity and the detuningδof the bichromatic field remains unchanged,the intensity of each emitted peak remains invariant.The spontaneously emitted peak can be annihilated in the band gap and enhanced near the band edge in the anisotropic photonic crystals.Meanwhile,we also observe the fluorescence quenching phenomenon in the spontaneous emission spectra.The research in this paper provides the theoretical guidance for the control of atomic spontaneous emission.

Pancreatic neuroendocrine tumor detected by technetium-99m methoxy-2-isobutylisonitrile single photon emission computed tomography/computed tomography:A case report

BACKGROUND Pancreatic neuroendocrine tumors(NETs)account for about 1%–2%of pancreatic tumors and about 8%of all NETs.Computed tomography(CT),magnetic resonance imaging,and endoscopic ultrasound are common imaging modalities for the diagnosis of pancreatic NETs.Furthermore,somatostatin receptor imaging is of great value for diagnosing pancreatic NETs.Herein,we report the efficacy of technetium-99m methoxy-2-isobutylisonitrile(99mTc-MIBI)single photon emission CT(SPECT)/CT for detecting pancreatic NETs.CASE SUMMARY A 57-year-old woman presented to our hospital with a 1-d history of persistent upper abdominal distending pain.The distending pain in the upper abdomen was aggravated after eating,with nausea and retching.Routine blood test results showed a high neutrophil percentage,low leukomonocyte and monocyte percentages,and low leukomonocyte and eosinophil counts.Amylase,liver and kidney function,and tumor markers alpha-fetoprotein,carcinoembryonic antigen,and cancer antigen(CA)125,CA72-4,CA19-9,and CA153 were normal.Abdominal CT showed a mass,with multiple calcifications between the pancreas and the spleen.The boundary between the mass and the pancreas and spleen was poorly defined.Contrast-enhanced CT revealed that the upper abdominal mass was unevenly and gradually enhanced.99mTc-MIBI SPECT/CT revealed that a focal radioactive concentration,with mild radioactive concentration extending into the upper abdominal mass,was present at the pancreatic body and tail.The 99mTc-MIBI SPECT/CT manifestations were consistent with the final pathological diagnosis of pancreatic NET.CONCLUSION 99mTc-MIBI SPECT/CT appears to be a valuable tool for detecting pancreatic NETs.

Endocrine radionuclide scintigraphy with fusion single photon emission computed tomography/computed tomography

AIM: To review the benefits of single photon emission computed tomography(SPECT)/computed tomography(CT) hybrid imaging for diagnosis of various endocrine disorders.METHODS: We performed MEDLINE and Pub Med searches using the terms: "SPECT/CT"; "functional anatomic mapping"; "transmission emission tomography"; "parathyroid adenoma"; "thyroid cancer"; "neuroendocrine tumor"; "adrenal"; "pheochromocytoma"; "paraganglioma"; in order to identify relevant articles published in English during the years 2003 to 2015. Reference lists from the articles were reviewed to identify additional pertinent articles. Retrieved manuscripts(case reports, reviews, meta-analyses and abstracts) concerning the application of SPECT/CT to endocrine imaging were analyzed to provide a descriptive synthesis of the utility of this technology.RESULTS: The emergence of hybrid SPECT/CT camera technology now allows simultaneous acquisition of combined multi-modality imaging, with seamless fusion of three-dimensional volume datasets. The usefulness of combining functional information to depict the biodistribution of radiotracers that map cellular processes of the endocrine system and tumors of endocrine origin, with anatomy derived from CT, has improved the diagnostic capability of scintigraphy for a range of disorders of endocrine gland function. The literature describes benefits of SPECT/CT for ^(99m)Tc-sestamibi parathyroid scintigraphy and ^(99m)Tc-pertechnetate thyroid scintigraphy, ^(123)I- or ^(131)I-radioiodine for staging of differentiated thyroid carcinoma, ^(111)In- and ^(99m)Tclabeled somatostatin receptor analogues for detection of neuroendocrine tumors, ^(131)I-norcholesterol(NP-59) scans for assessment of adrenal cortical hyperfunction, and ^(123)I- or ^(131)I-metaiodobenzylguanidine imaging for evaluation of pheochromocytoma and paraganglioma.CONCLUSION: SPECT/CT exploits the synergism between the functional information from radiopharmaceutical imaging and anatomy from CT, translating to improved diagnostic accuracy and meaningful impact on patient care.

Marked Increases in Background Photon Emissions in Sudbury Ontario More than One Week before the Magnitude >8.0 Earthquakes in Japan and Chile

Daily, minute-to-minute measurements of ground level photon emissions in Sudbury, Ontario Canada displayed conspicuous increases more than one week before the 2011 M9.0 earthquake in Japan and the 2010 M8.8 earthquake in Chile. Temporal profiles of the antecedent increase and subsequent decline in power densities for the two events were remarkably similar. Antecedent changes for 7.0 8.0) seismic events anywhere on the planet.

“Doubling” of local photon emissions when two simultaneous, spatially-separated, chemiluminescent reactions share the same magnetic field configurations

The aim of the present experiments was to discern if the “entanglement”-like photon emissions from pairs of cell cultures or human brains separated by significant distances but sharing the same circling magnetic field could be demonstrated with a classic chemiluminescent reaction produced by hydrogen peroxide and hypochlorite. Simultaneous injection of the same amount of peroxide into a local dish (above a photomultiplier tube) and a dish 10 m away in a closed chamber produced a “doubling” of the durations of the photon spikes only when the two reactions were placed in the center of separate spaces around each of which magnetic fields were generated as accelerating group velocities containing decreasing phase modulations followed by decelerating group velocities embedded with increasing phase modulations. The duration of this “entanglement” was about 8 min. These results suggest that separate distances behave as if they were “the same space” if they are exposed to the same precise temporal configuration of magnetic fields with specific angular velocities.

Spontaneous emission from an atom in a photonic crystal with two coherent bands

The dynamic and the radiative properties of an excited three-level atom embedded in an anisotropic photonic crystal with two coherent bands are investigated.The relative position of the atom in a Wigner-Seitz cell is described with a position-dependent parameter 胃（r0）,which is used as the coherent parameter for the two bands.The result shows that the dynamic properties of the atomic system are not only determined by atomic transition frequencies,but also affected by the gap width and the coherence of the two bands.In addition,the spontaneous emission spectrum of the atomic transition in free space is discussed.The center and the intensity of the spectrum can be obviously manipulated via the coherent parameter.

Photon Cascade Emission through Energy Transfer in Pr^(3+) and Er^(3+) Codoped System

Energy transfer processes in Pr 3+ and Er 3+-codoped CaAl 12O 19 crystal from 12 to 290 K were studied. Energy transfer from Pr 3+ to Er 3+ ions in this system was observed. The transfer can partially convert the 1S 0 UV fluorescence of Pr 3+ into green emission of the characteristic of Er 3+. The efficiency of the energy transfer was estimated based of the spectroscopic data. The temperature dependence on the transfer was also discussed.

Modification of the spontaneous emission of quantum dots near the surface of a three-dimensional colloidal photonic crystal

This paper demonstrates experimentally and numerically that a significant modification of spontaneous emission rate can be achieved near the surface of a three-dimensional photonic crystal. In experiments, semiconductor coreshell quantum dots are intentionally confined in a thin polymer film on which a three-dimensional colloidal photonic crystal is fabricated. The spontaneous emission rate of quantum dots is characterised by conventional and time-resolved photoluminescence （PL） measurements. The modification of the spontaneous emission rate, which is reflected in the change of spectral shape and PL lifetime, is clearly observed. While an obvious increase in the PL lifetime is found at most wavelengths in the band gap, a significant reduction in the PL lifetime by one order of magnitude is observed at the short-wavelength band edge. Numerical simulation reveals a periodic modulation of spontaneous emission rate with decreasing modulation strength when an emitter is moved away from the surface of the photonic crystal. It is supported by the fact that the modification of spontaneous emission rate is not pronounced for quantum dots distributed in a thick polymer film where both enhancement and suppression are present simultaneously. This finding provides a simple and effective way for improving the performance of light emitting devices.

Three-dimensional stereotactic surface projection in the statistical analysis of single photon emission computed tomography data for distinguishing between Alzheimer's disease and depression

AIM To evaluate usefulness of single photon emission computed tomography(SPECT) with three-dimensional stereotactic surface projection(3D-SSP) in distinguishing between Alzheimer's disease(AD) and depression.METHODS We studied 43 patients who presented with both depressive symptoms and memory disturbance. Each subject was evaluated using the following:(1) the Minimal Mental State Examination;(2) the Hamilton Rating Scale for Depression;(3) Clinical Global Impression-Severity scale(CGI-S); and(4) SPECT imaging with 3D-SSP.RESULTS The MMSE scores correlated significantly with the maximum Z-scores of AD-associated regions. CGI-S scores correlated significantly with the maximum Z-scores of depression-associated regions. Factor analysis identified three significant factors. Of these, Factor 1 could be interpreted as favouring a tendency for AD, Factor 2 as favouring a tendency for pseudo-dementia, and Factor 3 as favouring a depressive tendency.CONCLUSION We investigated whether these patients could be categorized as types: Type A(true AD), Type B(pseudodementia), Type C(occult AD), and Type D(true depression). The factor scores in factor analysis supported the validity of this classification. Our results suggest that SPECT with 3D-SSP is highly useful for distinguishing between depression and depressed mood in the early stage of AD.

Quantification of Tc-99m-ethyl cysteinate dimer brain single photon emission computed tomography images using statistical probabilistic brain atlas in depressive end-stage renal disease patients:Correlation with disease severity and symptom factors

This study adapted a statistical probabilistic anatomical map of the brain for single photon emission computed tomography images of depressive end-stage renal disease patients. This research aimed to investigate the relationship between symptom clusters, disease severity, and cerebral blood flow. Twenty-seven patients （16 males, 11 females） with stages 4 and 5 end-stage renal disease were enrolled, along with 25 healthy controls. All patients underwent depressive mood assessment and brain single photon emission computed tomography. The statistical probabilistic anatomical map images were used to calculate the brain single photon emission computed tomography counts. Asymmetric index was acquired and Pearson correlation analysis was performed to analyze the correlation between symptom factors, severity, and regional cerebral blood flow. The depression factors of the Hamilton Depression Rating Scale showed a negative correlation with cerebral blood flow in the left amygdale. The insomnia factor showed negative correlations with cerebral blood flow in the left amygdala, right superior frontal gyrus, right middle frontal gyrus, and left middle frontal gyrus. The anxiety factor showed a positive correlation with cerebral glucose metabolism in the cerebellar vermis and a negative correlation with cerebral glucose metabolism in the left globus pailidus, right inferior frontal gyrus, both temporal poles, and left parahippocampus. The overall depression severity （total scores of Hamilton Depression Rating Scale） was negatively correlated with the statistical probabilistic anatomical map results in the left amygdala and right inferior frontal gyrus. In conclusion, our results demonstrated that the disease severity and extent of cerebral blood flow quantified by a probabilistic brain atlas was related to various brain areas in terms of the overall severity and symptom factors in end-stage renal disease patients.

Four Years of Daily Photon Emissions That Have Predicted Major Earthquakes: Raw Data, Spectral Power Density Analyses and Implications for the Geosciences

The daily median ground surface flux densities per day from a continuously operating photomultiplier tube unit for four years in Sudbury, Ontario are presented for December 2010 to December 2014. Increases of about 2 to 4 PMT units (1 unit = 5 × 10-11 W·m-2) for median daily measures reliably occurred about two weeks before M ≥ 7.7 earthquakes anywhere on the planet. The PMT units, until June 2014, usually returned to baseline within a few days after the events. There has been a slow positive drift in flux power density since about 2012 and a conspicuous maintained increase after May, 2014. The equivalent energy per day if it were represented isotropically within the volume occupied by the earth is the same order of magnitude as the average daily global total seismic energy release. Spectral power densities revealed enhanced peaks (periodicities) between 100 to 150 days, 60 days, 30 days, and 25 days. Discriminable peaks in power were noted around 18 days, 14 days, and 4 to 6 days. These results suggest that continuous measurement of photonemissions within hyper-dark conditions may reveal geophysical processes that precede larger seismic events and could reflect the movement of the earth-solar system around the galactic center.

Cross-Polarized Single Photon Emission from Single Semiconductor Quantum Dots with V-Type Level Driven by Pulse Field

The statistic properties of photon emissions from single semiconductor quantum dots with V-type leveldriven by pulses are investigated theoretically.Based on quantum regression theorem and master equations,the dynamicequations of the second-order correlation function of the photon emissions are deduced.The calculated results reveal thatthe efficiency of single photon emissions from two orthogonal polarization eigenstates(|x〉and |y〉)reaches the maximumwhen the input pulses area is about π,and the probability of the cross-polarized single photon emission from |x〉and |y〉decreases with increasing of pulse width.

Same day yttrium-90 radioembolization with single photon emission computed tomography/computed tomography: An opportunity to improve care during the COVID-19 pandemic and beyond

BACKGROUND The coronavirus disease 2019(COVID-19)pandemic has made it more challenging for patients to undergo yttrium-90(Y-90)radioembolization(RE).Same day Y-90 RE provides an opportunity to minimize logistical challenges and infection risk associated with COVID-19,thus improving patient access.AIM To describe the use of same day Y-90 RE with routine single photon emission computed tomography/computed tomography(SPECT/CT)in order to optimize therapy.METHODS All patients were selected for Y-90 RE through a multidisciplinary tumor board,and were screened and tested for COVID-19 infection per institutional protocol.A same day procedure was developed,consisting of angiography,imaging,and Y-90 resin particle delivery.Routine SPECT/CT after technetium-99m macroaggregated albumin(Tc-99m MAA)administration was performed for assessment of arterial supply,personalized dosimetry,and extrahepatic activity.Post-treatment Y-90 bremsstrahlung SPECT/CT was performed for confirmation of particle delivery,by utilization of energy windowing to limit signal from previously administered Tc-99m MAA particles.RESULTS A total of 14 patients underwent same day Y-90 RE between March and June 2020.Mean lung shunt fraction was 6.13%(range 3.5%-13.1%).Y-90 RE was performed for a single lesion in 7 patients,while the remaining 7 patients had treatment of multifocal lesions.The largest lesion measured 8.3 cm.All patients tolerated the procedure well and were discharged the same day.CONCLUSION Same day Y-90 RE with resin-based microspheres is feasible,and provides an opportunity to mitigate infection risk and logistical challenges associated with the COVID-19 pandemic and beyond.We recommend consideration of SPECT/CT,especially among patients with complex malignancies,for the potential to improve outcomes and eligibility of patients to undergo same day Y-90 RE.

Au Microdisk-Size Dependence of Quantum Dot Emission from the Hybrid Metal-Distributed Bragg Reflector Structures Employed for Single Photon Sources

We investigate metallic microdisk-size dependence of quantum dot （QD） spontaneous emission rate and micro- antenna directional emission effect for the hybrid metM-distributed Bragg reflector structures based on a particular single QD emission. It is found that the measured photolumineseence （PL） intensity is very sensitive to the size of metMlic disk, showing an enhancement factor of 11 when the optimal disk diameter is 2μm and the numerical aperture of microscope objective NA=0.5. It is found that for large metal disks, the Purcell effect is dominant for enhanced PL intensity, whereas for small size disks the main contribution comes from plasmon scattering at the disk edge within the light cone collected by the microscope objective.

Cerebral functional imaging of Waiguan (SJ 5) acupoint specificity using single-photon emission computed tomography

The action of needling in acupoint therapy has to first be regulated and integrated by the brain, and then it affects the target organ and manifests its therapeutic effects, which is dependent on the specificity of the acupoints. The authors put forward the hypothesis of the ＂acupoint-related brain＂. Single-photon emission computed tomography was used to explore the activation of brain regions following true needling in true acupoint Waiguan （SJ 5）, sham needling in true acupoint Waiguan, true needling in a sham point, and sham needling in a sham point. The relative specificity of Waiguan in normal persons was analyzed by observing changes in regional cerebral blood flow. Compared with the sham needling in true acupoint group and sham needling in the sham point group, acupuncture at Waiguan can activate brain regions controlling movement. Compared with true needling in the sham point group, acupuncture at Waiguan can also activate brain regions controlling movement. The results suggest that the specificity of needling at an acupoint is related to certain activated cerebral functional regions, which are associated with the clinical application of the acupoint.

Energy Conversion Mechanics for Photon Emission per Non-Local Hidden-Variable Theory

Problem-Energy conversion processes in optical phenomena are incompletely explained by wave theory or quantum mechanics. There is a need for ontologically rich explanations at the level of individual particles. Purpose: This paper reports on the application of a non-local hidden-variable solution called the Cordus theory to this problem. The method is directed to the systematic development of a conceptual framework of proposed causal mechanisms. Findings: It has long been known that the bonding commitments of the electron affect its energy behaviour but the mechanisms for this have been elusive. We show how the degree of bonding constraint on the electron determines how it processes excess energy. A key concept is that the span and frequency of the electron are inversely proportional. This explains why energy changes cause positional distress for the electron. Natural explanations are given for multiple emission phenomena: Absorbance;Saturation;Beer-Lambert law;Colour;Quantum energy states;Directional emission;Photoelectric effect;Emission of polarised photons from crystals;Refraction effects;Reflection;Transparency;Birefringence;Cherenkov radiation;Bremsstrahlung and Synchrotron radiation;Phase change at reflection;Force impulse at reflection and radiation pressure;Simulated emission (Laser). Originality: The paper elucidates a mechanism for how the electron responds to combinations of bonding constraint and pumped energy. The crucial insight is that the electron size and position(s) are coupled attributes of its frequency and energy, where the coupling is achieved via physical substructures. The theory is able to provide a logically coherent explanation for a wide variety of energy conversion phenomena.

Deep brain stimulation of the subthalamic nucleus treats Parkinson's disease through enhancing metabolic activity of the corpus striatum Verification by single photon emission computed tomography and positron emission tomography

BACKGROUND： Subthalamic nucleus deep brain stimulation （STN DBS） for Parkinson＇s disease （PD） has achieved good effects, but to date the mechanism of STN DBS remains poorly understood STN DBS may increase dopamine levels or metabolic activity of the corpus striatum. OBJECTIVE： To validate the effects of STN DBS on dopamine metabolism and glucose metabolism in the corpus striatum of hemiparkinsonian monkeys using single photon emission computed tomography （SPECT） and position emission tomography （PET）. DESIGN, TIME AND SET＇rING： A controlled animal study was performed at the Neurosurgery Laboratory, Changhai Hospital of the Second Military Medical University of Chinese PLA between January 2004 and December 2007. METHODS： Hemiparkinsonism was induced in adult Rhesus Macaque monkeys, which exhibit similar characteristics of PD in humans, through unilateral internal carotid artery infusion of 1-methy-4-phenyl-1, 2, 3, 6-tetrahydropyrindine. Following model establishment, stimulation electrodes were implanted in the right STN, and chronic high-frequency stimulation （60 μs pulse width, 130 Hz frequency, and 1.5-2.0 V pressure） was performed. MAIN OUTCOME MEASURES： The changes in dopamine transporter （DAT）, D2 receptor （D2R）, and glucose metabolism in the corpus striatum following STN DBS were observed using SPECT and PET. RESULTS： SPECT examination showed that DAT specific binding in the right corpus striatum was increased at 3 months after DBS compared with prior to stimulation, and D2R specific binding in the right corpus striatum gradually decreased near levels on the left （non-electrode-implanted） side within 3 months after DBS. PET examination showed that the glucose metabolism in the right corpus striatum was markedly increased at 3 months after effective DBS. Hemiparkinsonism monkeys showed improved left limb rigidity, increased activities, and stable gait under chronic high-frequency stimulation. CONCLUSION： STN DBS increased striatal DAT, decreased D2R, and enhanced glucose metabolism, suggesting that chronic, high-frequency STN stimulation enhanced the metabolic activity of the corpus striatum, a mechanism for improving the PD symptoms of hemiparkinsonian monkeys.