Heterokaryotypic monozygotic twins are rare. We report a set of monochorionic diamniotic twins complicated with lethal malformations and hydrops in one fetus at menstrual age of 16 weeks’. Sonographic appearances and...Heterokaryotypic monozygotic twins are rare. We report a set of monochorionic diamniotic twins complicated with lethal malformations and hydrops in one fetus at menstrual age of 16 weeks’. Sonographic appearances and genetic am-niocentesis result suggested for 45,X and 46,XY heterokaryotypic twins. Coexisting polyhydramnios found in the sac of severely malformed 45,X fetus threatened miscarriage and premature delivery. To salvage the phenotypically normal male fetus, the hydropic 45,X co-twin was selectively terminated by occlusion of its umbilical cord with bipolar dia-thermy. Complete cessation of funicular flow was achieved, resulting in normalization of total amniotic fluid volume. A healthy 2200-gram baby boy was born at 38 weeks’. His neurodevelopment was intact at 2 years of age. His physical examination was significant for slight growth delay (15 percentiles), with 6% of 45,X mosaicism found in his peripheral blood. Owing to the rarity of the cases, limited data is available regarding an optimal treatment for heterokaryotypic monochorionic twins with discordant lethal malformation. Intrauterine intervention may be offered should demise or permanent disabilities are imminent to the apparently normal fetus.展开更多
Objective: In this study we aimed to compare the effects of submucosal cauterization of the inferior turbinate with or without inferior partial turbinectomy. Materials and methods: In this prospective cohort study, 60...Objective: In this study we aimed to compare the effects of submucosal cauterization of the inferior turbinate with or without inferior partial turbinectomy. Materials and methods: In this prospective cohort study, 60 patients with inferior turbinate hypertrophy were randomized and divided into two groups. The first one was submitted to submucosal cauterization associated with partial turbinectomy, and the second one only submucous cauterization. Five items were assessed to compare both methods: pain, nasal bleeding, scarring, crustation and nasal air way patency. Follow-up was performed on days 1, 14, 30 and 3 months later. Results: In both groups crusting formation was similar. Reactionary hemorrhage was more common in turbinectomy group. Scarring showed better results in the turbinectomy group in the first month postoperative, airway patency showed good results in 80% of the patients with turbinectomy. Conclusion: Submucosal cauterization with inferior partial turbinectomy has yielded better nasal patency when compared to submucosal electrocautery ablation alone.展开更多
文摘Heterokaryotypic monozygotic twins are rare. We report a set of monochorionic diamniotic twins complicated with lethal malformations and hydrops in one fetus at menstrual age of 16 weeks’. Sonographic appearances and genetic am-niocentesis result suggested for 45,X and 46,XY heterokaryotypic twins. Coexisting polyhydramnios found in the sac of severely malformed 45,X fetus threatened miscarriage and premature delivery. To salvage the phenotypically normal male fetus, the hydropic 45,X co-twin was selectively terminated by occlusion of its umbilical cord with bipolar dia-thermy. Complete cessation of funicular flow was achieved, resulting in normalization of total amniotic fluid volume. A healthy 2200-gram baby boy was born at 38 weeks’. His neurodevelopment was intact at 2 years of age. His physical examination was significant for slight growth delay (15 percentiles), with 6% of 45,X mosaicism found in his peripheral blood. Owing to the rarity of the cases, limited data is available regarding an optimal treatment for heterokaryotypic monochorionic twins with discordant lethal malformation. Intrauterine intervention may be offered should demise or permanent disabilities are imminent to the apparently normal fetus.
文摘Objective: In this study we aimed to compare the effects of submucosal cauterization of the inferior turbinate with or without inferior partial turbinectomy. Materials and methods: In this prospective cohort study, 60 patients with inferior turbinate hypertrophy were randomized and divided into two groups. The first one was submitted to submucosal cauterization associated with partial turbinectomy, and the second one only submucous cauterization. Five items were assessed to compare both methods: pain, nasal bleeding, scarring, crustation and nasal air way patency. Follow-up was performed on days 1, 14, 30 and 3 months later. Results: In both groups crusting formation was similar. Reactionary hemorrhage was more common in turbinectomy group. Scarring showed better results in the turbinectomy group in the first month postoperative, airway patency showed good results in 80% of the patients with turbinectomy. Conclusion: Submucosal cauterization with inferior partial turbinectomy has yielded better nasal patency when compared to submucosal electrocautery ablation alone.
