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超声空化在船舶与海洋工程中的应用
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作者 黄潇 牛广贇 +3 位作者 谢元吉 陈效鹏 胡海豹 潘光 《哈尔滨工程大学学报(英文版)》 CSCD 2024年第1期23-38,共16页
Biofouling on ships and offshore structures has always been a difficult problem to solve,which not only jeopardizes the structural strength but also brings great economic losses.Ultrasonic cavitation is expected to so... Biofouling on ships and offshore structures has always been a difficult problem to solve,which not only jeopardizes the structural strength but also brings great economic losses.Ultrasonic cavitation is expected to solve this problem due to its characteristics of no damage to structures and no pollution.Starting from the phenomenon and mechanism of ultrasonic cleaning,this paper introduces the application of ultrasonic cavitation in ship,pipeline and oil cleaning as well as ballast water treatment.By reviewing the existing studies,limitations such as insufficient ultrasonic parameter studies,lack of uniform cleanliness standards,and insufficient cavitation studies are summarized to provide traceable research ideas for improving ultrasonic cavitation technology and to guide the expansion and improvement of its applications. 展开更多
关键词 Ultrasonic cavitation Cavitation mechanism Ultrasonic cleaning Ship and marine engineering Application status
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Microstructure and forming mechanism of metals subjected to ultrasonic vibration plastic forming: A mini review
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作者 Qinghe Cui Xuefeng Liu +4 位作者 Wenjing Wang Shaojie Tian Vasili Rubanik Vasili Rubanik Jr. Dzmitry Bahrets 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2024年第6期1322-1332,共11页
Compared with traditional plastic forming,ultrasonic vibration plastic forming has the advantages of reducing the forming force and improving the surface quality of the workpiece.This technology has a very broad appli... Compared with traditional plastic forming,ultrasonic vibration plastic forming has the advantages of reducing the forming force and improving the surface quality of the workpiece.This technology has a very broad application prospect in industrial manufactur-ing.Researchers have conducted extensive research on the ultrasonic vibration plastic forming of metals and laid a deep foundation for the development of this field.In this review,metals were classified according to their crystal structures.The effects of ultrasonic vibration on the microstructure of face-centered cubic,body-centered cubic,and hexagonal close-packed metals during plastic forming and the mech-anism underlying ultrasonic vibration forming were reviewed.The main challenges and future research direction of the ultrasonic vibra-tion plastic forming of metals were also discussed. 展开更多
关键词 ultrasonic vibration plastic forming crystal structure MICROSTRUCTURE forming mechanism
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A Novel On-Site-Real-Time Method for Identifying Characteristic Parameters Using Ultrasonic Echo Groups and Neural Network
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作者 Shuyong Duan Jialin Zhang +2 位作者 Heng Ouyang Xu Han Guirong Liu 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2024年第1期215-228,共14页
On-site and real-time non-destructive measurement of elastic constants for materials of a component in a in-service structure is a challenge due to structural complexities,such as ambiguous boundary,variable thickness... On-site and real-time non-destructive measurement of elastic constants for materials of a component in a in-service structure is a challenge due to structural complexities,such as ambiguous boundary,variable thickness,nonuniform material properties.This work develops for the first time a method that uses ultrasound echo groups and artificial neural network(ANN)for reliable on-site real-time identification of material parameters.The use of echo groups allows the use of lower frequencies,and hence more accommodative to structural complexity.To train the ANNs,a numerical model is established that is capable of computing the waveform of ultrasonic echo groups for any given set of material properties of a given structure.The waveform of an ultrasonic echo groups at an interest location on the surface the structure with material parameters varying in a predefined range are then computed using the numerical model.This results in a set of dataset for training the ANN model.Once the ANN is trained,the material parameters can be identified simultaneously using the actual measured echo waveform as input to the ANN.Intensive tests have been conducted both numerically and experimentally to evaluate the effectiveness and accuracy of the currently proposed method.The results show that the maximum identification error of numerical example is less than 2%,and the maximum identification error of experimental test is less than 7%.Compared with currently prevailing methods and equipment,the proposefy the density and thickness,in addition to the elastic constants.Moreover,the reliability and accuracy of inverse prediction is significantly improved.Thus,it has broad applications and enables real-time field measurements,which has not been fulfilled by any other available methods or equipment. 展开更多
关键词 Parameter identification Ultrasonic echo group High-precision modeling Artificial neural network NDT
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Damage Evolution of Ballastless Track Concrete Exposed to Flexural Fatigue Loads:The Application of Ultrasonic Pulse Velocity,Impact-echo and Surface Electrical Resistance Method
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作者 杨志强 李化建 +4 位作者 WEN Jiaxing DONG Haoliang HUANG Fali WANG Zhen YI Zhonglai 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS CSCD 2024年第2期353-363,共11页
In order to clarify the fatigue damage evolution of concrete exposed to flexural fatigue loads,ultrasonic pulse velocity(UPV),impact-echo technology and surface electrical resistance(SR) method were used.Damage variab... In order to clarify the fatigue damage evolution of concrete exposed to flexural fatigue loads,ultrasonic pulse velocity(UPV),impact-echo technology and surface electrical resistance(SR) method were used.Damage variable based on the change of velocity of ultrasonic pulse(Du) and impact elastic wave(Di)were defined according to the classical damage theory.The influences of stress level,loading frequency and concrete strength on damage variable were measured.The experimental results show that Du and Di both present a three-stages trend for concrete exposed to fatigue loads.Since impact elastic wave is more sensitive to the microstructure damage in stage Ⅲ,the critical damage variable,i e,the damage variable before the final fracture of concrete of Di is slightly higher than that of Du.Meanwhile,the evolution of SR of concrete exposed to fatigue loads were analyzed and the relationship between SR and Du,SR and Di of concrete exposed to fatigue loads were established.It is found that the SR of concrete was decreased with the increasing fatigue cycles,indicating that surface electrical resistance method can also be applied to describe the damage of ballastless track concrete exposed to fatigue loads. 展开更多
关键词 ballastless track fatigue damage ultrasonic pulse velocity IMPACT-ECHO surface electrical resistance
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Comparative analysis of single-crater parameters in ultrasonic-assisted and unassisted micro-EDM of Ti6Al4V using discharge plasma imaging
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作者 Sohaib Raza Chandrakant Nirala 《Nanotechnology and Precision Engineering》 EI CAS CSCD 2024年第2期11-24,共14页
Ultrasonic-assisted micro-electro-discharge machining(EDM)has the potential to enhance processing responses such as material removal rate(MRR)and surface finish.To understand the reasons for this enhancement,the physi... Ultrasonic-assisted micro-electro-discharge machining(EDM)has the potential to enhance processing responses such as material removal rate(MRR)and surface finish.To understand the reasons for this enhancement,the physical mechanisms responsible for the individual discharges and the craters that they form need to be explored.This work examines features of craters formed by single discharges at various parameter values in both conventional and ultrasonic-assistedEDM of Ti6Al4V.High-speed imaging of the plasma channel is performed,and data on the individual discharges are captured in real-time.A 2D axisymmetric model using finite element software is established to model crater formation.On the basis of simulation and experimental results,a comparative study is then carried out to examine the effects of ultrasonic vibrational assistance on crater geometry.For every set ofEDM parameters,the crater diameter and depth from a single discharge are found to be higher in ultrasonic-assistedEDM than in conventionalEDM.The improved crater geometry and the reduced bulge formation at the crater edges are attributed to the increased melt pool velocity and temperature predicted by the model. 展开更多
关键词 Ultrasonic vibration Discharge crater Plasma diameter Single discharge
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Understanding the spatial interaction of ultrasounds based on three-dimensional dual-frequency ultrasonic field numerical simulation
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作者 Zhao-yang Yin Qi-chi Le +3 位作者 Yan-chao Jiang Da-zhi Zhao Qi-yu Liao Qi Zou 《China Foundry》 SCIE EI CAS CSCD 2024年第1期29-43,共15页
A transient 3D model was established to investigate the effect of spatial interaction of ultrasounds on the dual-frequency ultrasonic field in magnesium alloy melt.The effects of insertion depth and tip shape of the u... A transient 3D model was established to investigate the effect of spatial interaction of ultrasounds on the dual-frequency ultrasonic field in magnesium alloy melt.The effects of insertion depth and tip shape of the ultrasonic rods,input pressures and their ratio on the acoustic field distribution were discussed in detail.Additionally,the spacing,angle,and insertion depth of two ultrasonic rods significantly affect the interaction between distinct ultrasounds.As a result,various acoustic pressure distributions and cavitation regions are obtained.The spherical rods mitigate the longitudinal and transversal attenuation of acoustic pressure and expand the cavitation volume by 53.7%and 31.7%,respectively,compared to the plate and conical rods.Increasing the input pressure will enlarge the cavitation region but has no effect on the acoustic pressure distribution pattern.The acoustic pressure ratio significantly affects the pressure distribution and the cavitation region,and the best cavitation effect is obtained at the ratio of 2:1(P15:P20). 展开更多
关键词 dual-frequency ultrasonic numerical model acoustic pressure spatial interaction magnesium alloy
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Improving fatigue properties of normal direction ultrasonic vibration assisted face grinding Inconel 718 by regulating machined surface integrity
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作者 Nianwei Xu Renke Kang +4 位作者 Bi Zhang Yuan Zhang Chenxu Wang Yan Bao Zhigang Dong 《International Journal of Extreme Manufacturing》 SCIE EI CAS CSCD 2024年第3期458-475,共18页
Fatigue properties are crucial for critical aero-engine components in extreme serviceenvironments,which are significantly affected by surface integrity(SI)indexes(especially surface topography,residual stressσ_(res),... Fatigue properties are crucial for critical aero-engine components in extreme serviceenvironments,which are significantly affected by surface integrity(SI)indexes(especially surface topography,residual stressσ_(res),and microhardness)after machining processes.Normal-direction ultrasonic vibration-assisted face grinding(ND-UVAFG)has advantages in improving the machinability of Inconel 718,but there is a competitive relationship between higher compressiveσ_(res)and higher surface roughness R_(a)in affecting fatigue strength.The lack of a quantitative relationship between multiple SI indexes and fatigue strength makes theindeterminacy of a regulatory strategy for improving fatigue properties.In this work,a model of fatigue strength(σ_f)_(sur)considering multiple SI indexes was developed.Then,high-cycle fatigue tests were carried out on Inconel 718 samples with different SI characteristics,and the influence of ND-UVAFG process parameters on SI was analyzed.Based on SI indexes data,the(σ_f)_(sur)distribution in the grinding surface layer for ND-UVAFG Inconel 718 samples was determined using the developed model,and then the fatigue crack initiation(FCI)sites were furtherpredicted.The predicted FCI sites corresponded well with the experimental results,therebyverifying this model.A strategy for improving the fatigue life was proposed in this work,which was to transfer the fatigue source from the machined surface to the bulk material by controlling the SI indexes.Finally,a critical condition of SI indexes that FCI sites appeared on the surface or in bulk material was given by fitting the predicted results.According to the critical condition,an SI field where FCI sites appeared in the bulk material could be obtained.In this field,thefatigue life of Inconel 718 samples could be improved by approximately 140%. 展开更多
关键词 surface integrity fatigue strength Inconel 718 ultrasonic assisted grinding
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Non-Kramers doublet ground state in a quaternary cubic compound PrRu_(2)In_(2)Zn_(18) investigated by ultrasonic measurements
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作者 张化远 Kazuhei Wakiya +2 位作者 Mitsuteru Nakamura Masahito Yoshizawa Yoshiki Nakanish 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第6期405-411,共7页
We performed ultrasonic measurements on a quaternary cubic compound PrRu_(2)In_(2)Zn_(18) to explore the ground state properties derived from non-Kramers Γ_(3) doublet of Pr^(3+).PrRu_(2)In_(2)Zn_(18) is a quaternary... We performed ultrasonic measurements on a quaternary cubic compound PrRu_(2)In_(2)Zn_(18) to explore the ground state properties derived from non-Kramers Γ_(3) doublet of Pr^(3+).PrRu_(2)In_(2)Zn_(18) is a quaternary derivative of the ternary compound PrRu_(2)Zn_(20) that exhibits a structural phase transition at T_S=138 K.In PrRu_(2)In_(2)Zn_(18),the Zn atoms at the 16c site in PrRu_(2)Zn_(20) are selectively replaced by In atoms.A monotonic increase was observed in the temperature dependence of elastic constants C_L=(C_(11)+2C_(12)+4C_(44))/3 and C_(T)=(C_(11)-C_(12)+C_(44))/3 in the temperature range around T_(S) to which an elastic softening was observed in(C_(11)-C_(12))/2 for PrRu_(2)Zn_(20).The disappearance of the softening indicates that the structural transition in PrRu_(2)Zn_(20) is suppressed by the substitution of Zn ions by In ones with a larger ionic radius.Alternatively,the C_(T) of PrRu_(2)In_(2)Zn_(18) exhibits a precursor Curie-type elastic softening toward low temperatures being responsible for the non-Kramers Γ_(3) ground state.We discuss the ground state and the evolution of the elastic properties of the different single-crystal samples of PrRu_(2)In_(2)Zn_(18) grown under different conditions. 展开更多
关键词 ultrasonic measurements non-Kramers doublet structural phase transition crystalline electric field effect
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Hybrid pedestrian positioning system using wearable inertial sensors and ultrasonic ranging
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作者 Lin Qi Yu Liu +2 位作者 Chuanshun Gao Tao Feng Yue Yu 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第3期327-338,共12页
Pedestrian positioning system(PPS)using wearable inertial sensors has wide applications towards various emerging fields such as smart healthcare,emergency rescue,soldier positioning,etc.The performance of traditional ... Pedestrian positioning system(PPS)using wearable inertial sensors has wide applications towards various emerging fields such as smart healthcare,emergency rescue,soldier positioning,etc.The performance of traditional PPS is limited by the cumulative error of inertial sensors,complex motion modes of pedestrians,and the low robustness of the multi-sensor collaboration structure.This paper presents a hybrid pedestrian positioning system using the combination of wearable inertial sensors and ultrasonic ranging(H-PPS).A robust two nodes integration structure is developed to adaptively combine the motion data acquired from the single waist-mounted and foot-mounted node,and enhanced by a novel ellipsoid constraint model.In addition,a deep-learning-based walking speed estimator is proposed by considering all the motion features provided by different nodes,which effectively reduces the cumulative error originating from inertial sensors.Finally,a comprehensive data and model dual-driven model is presented to effectively combine the motion data provided by different sensor nodes and walking speed estimator,and multi-level constraints are extracted to further improve the performance of the overall system.Experimental results indicate that the proposed H-PPS significantly improves the performance of the single PPS and outperforms existing algorithms in accuracy index under complex indoor scenarios. 展开更多
关键词 Pedestrian positioning system Wearable inertial sensors Ultrasonic ranging Deep-learning Data and model dual-driven
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Behaviors of cavitation bubbles driven by high-intensity ultrasound
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作者 黄晨阳 李凡 +5 位作者 冯释毅 王成会 陈时 胡静 何芯蕊 宋家凯 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第2期394-404,共11页
In a multi-bubble system, the bubble behavior is modulated by the primary acoustic field and the secondary acoustic field. To explore the translational motion of bubbles in cavitation liquids containing high-concentra... In a multi-bubble system, the bubble behavior is modulated by the primary acoustic field and the secondary acoustic field. To explore the translational motion of bubbles in cavitation liquids containing high-concentration cavitation nuclei,evolutions of bubbles are recorded by a high-speed camera, and translational trajectories of several representative bubbles are traced. It is found that translational motion of bubbles is always accompanied by the fragmentation and coalescence of bubbles, and for bubbles smaller than 10 μm, the possibility of bubble coalescence is enhanced when the spacing of bubbles is less than 30 μm. The measured signals and their spectra show the presence of strong negative pressure, broadband noise,and various harmonics, which implies that multiple interactions of bubbles appear in the region of high-intensity cavitation.Due to the strong coupling effect, the interaction between bubbles is random. A simplified triple-bubble model is developed to explore the interaction patterns of bubbles affected by the surrounding bubbles. Patterns of bubble interaction, such as attraction, repulsion, stable spacing, and rebound of bubbles, can be predicted by the theoretical analysis, and the obtained results are in good agreement with experimental observations. Mass exchange between the liquid and bubbles as well as absorption in the cavitation nuclei also plays an important role in multi-bubble cavitation, which may account for the weakening of the radial oscillations of bubbles. 展开更多
关键词 ultrasonic cavitation multi-bubble system translational motion of bubbles
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Preliminary study of the electrospray DPE peculiarities from the liquid surface in the presence of the CSWs
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作者 贺伟国 霍卫杰 +3 位作者 韩罗峰 朱康武 王锋 王泽坤 《Plasma Science and Technology》 SCIE EI CAS CSCD 2024年第5期110-120,共11页
The Ultrasonic Electric Propulsion(UEP)system is a cutting-edge propulsion technology that is mostly used on platforms for small satellites(less than 10 kg).The characteristics of droplet partial emissions(DPEs)in the... The Ultrasonic Electric Propulsion(UEP)system is a cutting-edge propulsion technology that is mostly used on platforms for small satellites(less than 10 kg).The characteristics of droplet partial emissions(DPEs)in the UEP system are investigated using a high-speed imaging technique(an ultra-high speed camera(NAC HX-6)and a long-distance microscope)in this work.The experiments demonstrate that there are a few partial emission modes,including left-side emission,double-side emission,and right-side emission,that are present in the droplet emission process of the UEP system.These modes are primarily caused by the partial formation of capillary standing waves(CSWs)on the emission surface of the ultrasonic nozzle.The emission rate for single-and double-sided emissions varies at different times,indicating that there are different CSWs engaged in droplet emission due to variations in the liquid film thickness and charge state of the liquid cones.Additionally,as the droplets emit continuously,a raised area on the emission surface appears,with several droplets emitting there as a result of charge accumulation.Additionally,photos of the CSWs with emitting droplets are obtained,which highlights the CSWs'distinctive wave morphology. 展开更多
关键词 ultrasonic electric propulsion system MICROSATELLITE high-speed imaging technique droplet partial emissions electric field
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Detection of internal crack growth in polyethylene pipe using guided wave ultrasonic testing
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作者 Jay Kumar Shah Hao Wang Said El-Hawwat 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2024年第2期319-329,共11页
Despite the success of guided wave ultrasonic inspection for internal defect detection in steel pipes,its application on polyethylene(PE)pipe remains relatively unexplored.The growth of internal cracks in PE pipe seve... Despite the success of guided wave ultrasonic inspection for internal defect detection in steel pipes,its application on polyethylene(PE)pipe remains relatively unexplored.The growth of internal cracks in PE pipe severely affects its pressure-holding capacity,hence the early detection of internal cracks is crucial for effective pipeline maintenance strategies.This study extends the scope of guided wave-based ultrasonic testing to detect the growth of internal cracks in a natural gas distribution PE pipe.Laboratory experiments and a finite element model were planned to study the wave-crack interaction at different stages of axially oriented internal crack growth with a piezoceramic transducer-based setup arranged in a pitch-catch configuration.Mode dispersion analysis supplemented with preliminary experiments was performed to isolate the optimal inspection frequency,leading to the selection of the T(0,1)mode at 50-kHz for the investigation.A transmission index based on the energy of the T(0,1)mode was developed to trace the extent of simulated crack growth.The findings revealed an inverse linear correlation between the transmission index and the crack depth for crack growth beyond 20%crack depth. 展开更多
关键词 polyethylene pipes internal cracks guided wave ultrasonic testing torsional modes finite element modeling
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Ultrasound-guided serratus anterior plane block enhances postoperative analgesia and recovery in thoracoscopic surgery
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作者 Jing-Jing Zhang Shao-Lin Wang +3 位作者 Lei He Ding-Dong Yang Wei Qian Ying Zhao 《World Journal of Clinical Cases》 SCIE 2024年第19期3717-3724,共8页
BACKGROUND The serratus anterior muscle,located in the lateral aspect of the thorax,plays a crucial role in shoulder movement and stability.Thoracoscopic surgery,while minimally invasive,often results in significant p... BACKGROUND The serratus anterior muscle,located in the lateral aspect of the thorax,plays a crucial role in shoulder movement and stability.Thoracoscopic surgery,while minimally invasive,often results in significant postoperative pain,complicating patient recovery and potentially extending hospital stays.Traditional anesthesia methods may not adequately address this pain,leading to increased complications such as agitation due to inadequate pain management.AIM To evaluate the application value of ultrasound-guided serratus anterior plane block(SAPB)in patients undergoing thoracoscopic surgery,focusing on its effects on postoperative analgesia and rehabilitation.METHODS Eighty patients undergoing thoracoscopic surgery between August 2021 and December 2022 were randomly divided into two groups:An observation group receiving ultrasound-guided SAPB and a control group receiving standard care without SAPB.Both groups underwent general anesthesia and were monitored for blood pressure,heart rate(HR),oxygen saturation,and pulse.The primary outcomes measured included mean arterial pressure(MAP),HR,postoperative visual analogue scale(VAS)scores for pain,supplemental analgesic use,and incidence of agitation.RESULTS The observation group showed significantly lower cortisol and glucose concentrations at various time points post-operation compared to the control group,indicating reduced stress responses.Moreover,MAP and HR levels were lower in the observation group during and after surgery.VAS scores were significantly lower in the observation group at 1 h,4 h,6 h,and 12 h post-surgery,and the rates of analgesic supplementation and agitation were significantly reduced compared to the control group.CONCLUSION Ultrasound-guided SAPB significantly improves postoperative analgesia and reduces agitation in patients undergoing thoracoscopic surgery.This technique stabilizes perioperative vital signs,decreases the need for supplemental analgesics,and minimizes postoperative pain and stress responses,underscoring its high application value in enhancing patient recovery and rehabilitation post-thoracoscopy. 展开更多
关键词 Ultrasonic guidance Serserus anterior plane block Thoracoscopic surgery Postoperative analgesia
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Research Progress of Atomizers and Drugs Used in Atomization Therapy
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作者 Bozhi LIU Haobo YANG +2 位作者 Yifei CHEN Xiaojing SUN Qian JIANG 《Medicinal Plant》 2024年第4期77-79,82,共4页
At present,the commonly used treatment methods for chronic respiratory diseases are drug,oxygen,interventional and atomization therapy.Atomization therapy is the most widely used because of its characteristics of fast... At present,the commonly used treatment methods for chronic respiratory diseases are drug,oxygen,interventional and atomization therapy.Atomization therapy is the most widely used because of its characteristics of fast effect,high local drug concentration,less drug dosage,convenient application and few systemic adverse reactions.In this paper,the mechanism,characteristics,commonly used drugs and clinical application of atomization therapy are discussed. 展开更多
关键词 Ultrasonic atomizer Atomized drugs Atomization therapy
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Analysis of Ultrasonic Emulsification Surgery and Small Incision Cataract Extracapsular Extraction Surgery for Cataract Clinical Treatment Level Improvement
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作者 Chunyan Ji 《Journal of Clinical and Nursing Research》 2024年第2期196-200,共5页
Objective:To analyze the efficacy of ultrasonic emulsification and small incision cataract extracapsular extraction in cataract patients.Methods:96 cataract patients admitted from May 2021 to May 2023 were selected an... Objective:To analyze the efficacy of ultrasonic emulsification and small incision cataract extracapsular extraction in cataract patients.Methods:96 cataract patients admitted from May 2021 to May 2023 were selected and randomly grouped into group A(ultrasonic emulsification)and group B(small-incision extracapsular cataract extraction),with 48 cases each.Results:At 1 week,1-month,and 3 months post-operation,the visual acuity of group A was higher and the astigmatism value was lower than that of group B(P<0.05);at 12h,24h,and 48h post-operation,the intraocular pressure of group A was higher than that of group B(P<0.05);the thickness of macular area of group A was lower than that of group B at 1 week and 1-month post-operation(P<0.05).Conclusion:Ultrasonic emulsification in cataract patients was slightly better than small incision cataract extracapsular extraction in correcting astigmatism,improving visual acuity,and regulating macular thickness.However,due to the high energy of ultrasonic emulsification,the risk of complications such as high postoperative intraocular pressure was higher.Small-incision extracapsular cataract extraction has better application value in economically disadvantaged areas. 展开更多
关键词 CATARACT Cataract ultrasonic emulsification Small incision cataract extracapsular extraction Therapeutic efficacy
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Clinical Efficacy of Ultrasonic Medicinal Penetration in the Removal of Blood Stasis and Alleviation of Zhuyu Juanbi Formula in the Treatment of Peripheral Neuropathy Induced by Paclitaxel
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作者 Ying Zhang Huixin Chen +2 位作者 Qirong Zhang Yingjie Jia Dan Yi 《Proceedings of Anticancer Research》 2024年第3期7-17,共11页
Objective: To observe the clinical efficacy and differences of the Zhuyu Juanbi formula delivered through ultrasound at Zusanli on patients with chemotherapy-induced peripheral neuropathy (CIPN) due to paclitaxel inje... Objective: To observe the clinical efficacy and differences of the Zhuyu Juanbi formula delivered through ultrasound at Zusanli on patients with chemotherapy-induced peripheral neuropathy (CIPN) due to paclitaxel injection. Methods: A total of 72 breast cancer patients with CIPN were randomly divided into two groups. The treatment group (36 cases) was treated with oral methylcobalamin plus ultrasonic medicine permeating Zhuyu Juanbi formulae, while the control group (36 cases) was treated with oral methylcobalamin alone. Following two 2 cycles of continuous treatment, the efficacy of peripheral neurotoxicity, TCM syndrome score, FACT/GOG-Ntx score, total neuropathy score, and safety indicators of gynecological cancer patients were observed in the two groups. Result: In the treatment of CIPN, the addition of ultrasonic medicine permeating Zhuyu Juanbi formulae was more effective than oral methylcobalamin alone in reducing peripheral neurotoxicity and improving the quality of life of patients. The difference between the two groups was statistically significant (P < 0.05), and ultrasound drug penetration Zhuyu Juanbi formulae significantly reduced the FACT/ GOG-Ntx score and TNS score in the treatment group. In terms of drug safety, it rarely caused adverse reactions such as grade 3 and 4 leukopenia, and the safety profile was therefore good. Conclusion: The combination of ultrasonic medicine permeating Zhuyu Juanbi formulae and methylcobalamin has been demonstrated to be an effective treatment for peripheral neurotoxicity in patients with PIPN. It has been shown to significantly improve the clinical symptoms of PIPN patients, improve the quality of life of patients, and have a good safety profile. 展开更多
关键词 Chemotherapy-induced peripheral neuropathy(CIPN) Paclitaxel-induced peripheral neuropathy Zhuyu Juanbi formulae Ultrasonic drug delivery
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Ultrasound application in alkaline pretreatment process of spodumene to improve particle floatability 被引量:1
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作者 Haoran Chu Lanlan Chen +3 位作者 Dongfang Lu Yuhua Wang Xiayu Zheng Guangli Zhu 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2023年第7期883-891,共9页
Selective surface dissolution was found to be important in spodumene flotation. In this study, we proposed to introduce ultrasound into the pretreatment process to accelerate particle vibration and cavitation, as well... Selective surface dissolution was found to be important in spodumene flotation. In this study, we proposed to introduce ultrasound into the pretreatment process to accelerate particle vibration and cavitation, as well as the migration of mineral surface components to solution. Micro-flotation results showed that the flotation recovery of spodumene can be 86.08% by ultrasound pretreatment, but only 39.30% by traditional mechanical agitation pretreatment. Compared with traditional mechanical agitation, ultrasonic pretreatment can shorten the pretreatment process, reduce the dosage of agents, reduce the mechanical agitation speed, and improve the efficiency of the pretreating process. Inductively coupled plasma analysis showed that, in the ultrasonic system, the amount of Li, Al, and Si species in the solution was twice as much as those in the traditional preprocessing system. Moreover, the scanning electron microscope results demonstrated a larger surface dissolution area in the ultrasonic system. X-Ray photoelectron spectroscopy results showed that the atomic concentration of Si species on the spodumene surface decreased, whereas the relative atomic concentrations of Li and Al species increased, indicating that the ultrasound effect strengthened the selective dissolution of elements on the mineral surface.The high-resolution spectra of O 1s showed that more collectors are adsorbed on the mineral surface treated by ultrasonic pretreatment. 展开更多
关键词 Ultrasonic pretreatment SPODUMENE FLOTATION Surface selective dissolution
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Simultaneous measurement of velocity profile and liquid film thickness in horizontal gas–liquid slug flow by using ultrasonic Doppler method 被引量:1
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作者 Lusheng Zhai Bo Xu +1 位作者 Haiyan Xia Ningde Jin 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2023年第6期323-340,共18页
Horizontal gas-liquid two-phase flows widely exist in chemical engineering,oil/gas production and other important industrial processes.Slug flow pattern is the main form of horizontal gas-liquid flows and characterize... Horizontal gas-liquid two-phase flows widely exist in chemical engineering,oil/gas production and other important industrial processes.Slug flow pattern is the main form of horizontal gas-liquid flows and characterized by intermittent motion of film region and slug region.This work aims to develop the ultrasonic Doppler method to realize the simultaneous measurement of the velocity profile and liquid film thickness of slug flow.A single-frequency single-channel transducer is adopted in the design of the field-programmable gate array based ultrasonic Doppler system.A multiple echo repetition technology is used to improve the temporal-spatial resolution for the velocity profile.An experiment of horizontal gas-liquid two-phase flow is implemented in an acrylic pipe with an inner diameter of 20 mm.Considering the aerated characteristics of the liquid slug,slug flow is divided into low-aerated slug flow,high-aerated slug flow and pseudo slug flow.The temporal-spatial velocity distributions of the three kinds of slug flows are reconstructed by using the ultrasonic velocity profile measurement.The evolution characteristics of the average velocity profile in slug flows are investigated.A novel method is proposed to derive the liquid film thickness based on the instantaneous velocity profile.The liquid film thickness can be effectively measured by detecting the position and the size of the bubbles nearly below the elongated gas bubble.Compared with the time of flight method,the film thickness measured by the Doppler system shows a higher accuracy as a bubble layer occurs in the film region.The effect of the gas distribution on the film thickness is uncovered in three kinds of slug flows. 展开更多
关键词 Gas–liquid flow Complex fluids Measurement Ultrasonic Doppler Velocity profile Liquid film thickness
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A novel method towards improving the hydrogen storage properties of hypoeutectic Mg-Ni alloy via ultrasonic treatment 被引量:1
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作者 Xin Ding Ruirun Chen +4 位作者 Xiaoyu Chen Hongze Fang Qi Wang Yanqing Su Jingjie Guo 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2023年第3期903-915,共13页
Ultrasonic treatment has great contributions on modifying the morphology,dimension and distribution of constituent phases during solidification,which serve as dominate factors influencing the hydrogen storage performa... Ultrasonic treatment has great contributions on modifying the morphology,dimension and distribution of constituent phases during solidification,which serve as dominate factors influencing the hydrogen storage performance of Mg-based alloys.In this research,ultrasonic treatment is utilized as a novel method to enhance the de-/hydriding properties of Mg-2Ni(at.%)alloy.Due to ultrasonic treatment,the microstructure of as-cast alloy is significantly refined and homogenized.Ascribing to the increased eutectic boundaries and shortened distance insideα-Mg for hydrogen atoms diffusion,the hydrogen uptake capacities and isothermal de-/hydriding rates improve effectively,especially at lower temperature.The peak desorption temperature reduces from 392.99°C to 345.56°C,and the dehydriding activation energy decreases from 101.93 k J mol^(-1)to 88.65 k J mol^(-1).Weakened hysteresis of plateau pressures and slightly optimized thermodynamics are determined from the pressure-composition isotherms.Owing to the refined primary Mg,a larger amount of hydrogen with the higher hydriding proportion is absorbed in the first stage when hydrides nucleate in eutectic region and grow on primary Mg periphery subsequently before MgH2colonies impinging,resulting in the enhancement of hydrogenation rates and capacities. 展开更多
关键词 Hydrogen storage Mg-Ni alloy Ultrasonic treatment Dehydriding kinetics
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Structure and allergenicity of a-lactalbumin:effects of ultrasonic prior to glycation and subsequent phosphorylation 被引量:1
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作者 Wenmei Chen Qiongzhen Chen +4 位作者 Houze Zhou Yanhong Shao Yang Wang Jun Liu Zongcai Tu 《Food Science and Human Wellness》 SCIE CSCD 2023年第3期825-831,共7页
Bovineα-lactalbumin(BLA)induced severe cow's milk allergy.In this study,a novel strategy combining ultrasonication,performed before glycation,and phosphorylation was proposed to reduce BLA allergenicity.Result sh... Bovineα-lactalbumin(BLA)induced severe cow's milk allergy.In this study,a novel strategy combining ultrasonication,performed before glycation,and phosphorylation was proposed to reduce BLA allergenicity.Result showed that IgE-and IgG-binding capacities and the release rates of histamine and interleukin-6 from RBL-2 H3 were reduced.Moreover,intrinsic fluorescence intensity and surface hydrophobicity were decreased,whereas glycated sites(R10,N44,K79,K108,N102 and K114)and phosphorylated sites(Y36 and S112)of BLA were increased.Minimum allergenicity was detected during BLA treatment after ultrasonic prior to glycation and subsequent phosphorylation because of considerable increase in glycated and phosphorylated sites.Therefore,the decrease in allergenicity of BLA,the effect correlated well with the shielding effect of glycated sites combined with phosphorylated sites and the conformational changes.This study provides important theoretical foundations for improving and using the ultrasonic technology combined with protein modification in allergenic protein processing. 展开更多
关键词 Bovineα-lactalbumin ALLERGENICITY ULTRASONIC Protein modification
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