AIM:To evaluate the efficacy of endoscopic ultrasonography(EUS) in patients with elevated carbohydrate antigen(CA) 19-9 levels of obscure origin.METHODS:Patients who had visited Pusan National University Hospital beca...AIM:To evaluate the efficacy of endoscopic ultrasonography(EUS) in patients with elevated carbohydrate antigen(CA) 19-9 levels of obscure origin.METHODS:Patients who had visited Pusan National University Hospital because of elevated serum CA 19-9 levels,between January 2007 and December 2009,were retrospectively enrolled.EUS had been performed on all subjects,in addition to routine blood tests,endoscopy,abdominal computed tomography(CT) and other clinical exams,which had not revealed any abnormal findings suggestive of the origin of the elevated CA 19-9 levels.RESULTS:Of the 17 patients,gallbladder sludge was detected in 16 patients(94.1%) and common bile duct sludge was observed in 3 patients(17.6%).After the administration of ursodeoxycholic acid to 12 of the patients with gallbladder sludge,CA 19-9 levels normalized in 6 of the patients after a median of 4.5 mo.CONCLUSION:EUS is a useful diagnostic method for patients with elevated CA 19-9 levels of obscure origin,even if the reason for abnormal levels of this serum marker cannot be determined through prior examinations,including abdominal CT.展开更多
目的比较三维子宫输卵管超声造影(3D-Hy Co Sy)和四维子宫输卵管超声造影(4D-Hy Co Sy)诊断不孕症患者输卵管通畅性的临床价值。方法 40例不孕症患者,其中20例进行3D-Hy Co Sy检查,20例进行4D-Hy Co Sy检查,分析图像质量,并分别与造影...目的比较三维子宫输卵管超声造影(3D-Hy Co Sy)和四维子宫输卵管超声造影(4D-Hy Co Sy)诊断不孕症患者输卵管通畅性的临床价值。方法 40例不孕症患者,其中20例进行3D-Hy Co Sy检查,20例进行4D-Hy Co Sy检查,分析图像质量,并分别与造影后腹腔镜下通染液检查结果对照,评价两种造影方法的诊断效能。结果 3D-Hy Co Sy的图像有80.0%(16/20)适于诊断,4D-Hy Co Sy的图像有95.0%(19/20)适于诊断。3D-Hy Co Sy诊断输卵管通畅性的准确率为85.0%,敏感性为90.9%,特异性为77.8%,阳性预测值为83.3%,阴性预测值为87.5%;4D-Hy Co Sy诊断输卵管通畅性的准确率为90.0%,敏感性为95.0%,特异性为85.0%,阳性预测值为86.4%,阴性预测值为94.4%。两种方法与腹腔镜通染液检查结果均有良好的一致性。结论 3D-Hy Co Sy和4D-Hy Co Sy诊断输卵管通畅性均准确可行,但3D-Hy Co Sy图像单一,信息较少,不易诊断,而4D-Hy Co Sy动态直观,信息丰富,易于诊断,因此4D-Hy Co Sy评价输卵管通畅性更具优势。展开更多
During the past decades,early fetal ultrasound and diagnosis have increasingly gained attention in pregnancy care with the development of high-frequency transducers,which make it possible to obtain detailed images of ...During the past decades,early fetal ultrasound and diagnosis have increasingly gained attention in pregnancy care with the development of high-frequency transducers,which make it possible to obtain detailed images of the early fetus and its organs,and thus move part of the anatomy and anomaly scan from the second to the first-trimester.By transabdominal sonography or transvaginal sonography,or a combination of both approaches,it is now able to diagnose a wide variety of fetal abnormalities at 11-13^(+6)weeks.展开更多
基金Supported by A grant from the National R&D Program for Cancer Control,Ministry for Health,Welfare and Family Affairs, Republic of Korea,No.0920050Pusan National University Hospital Clinical Research Grant(2012)
文摘AIM:To evaluate the efficacy of endoscopic ultrasonography(EUS) in patients with elevated carbohydrate antigen(CA) 19-9 levels of obscure origin.METHODS:Patients who had visited Pusan National University Hospital because of elevated serum CA 19-9 levels,between January 2007 and December 2009,were retrospectively enrolled.EUS had been performed on all subjects,in addition to routine blood tests,endoscopy,abdominal computed tomography(CT) and other clinical exams,which had not revealed any abnormal findings suggestive of the origin of the elevated CA 19-9 levels.RESULTS:Of the 17 patients,gallbladder sludge was detected in 16 patients(94.1%) and common bile duct sludge was observed in 3 patients(17.6%).After the administration of ursodeoxycholic acid to 12 of the patients with gallbladder sludge,CA 19-9 levels normalized in 6 of the patients after a median of 4.5 mo.CONCLUSION:EUS is a useful diagnostic method for patients with elevated CA 19-9 levels of obscure origin,even if the reason for abnormal levels of this serum marker cannot be determined through prior examinations,including abdominal CT.
文摘目的比较三维子宫输卵管超声造影(3D-Hy Co Sy)和四维子宫输卵管超声造影(4D-Hy Co Sy)诊断不孕症患者输卵管通畅性的临床价值。方法 40例不孕症患者,其中20例进行3D-Hy Co Sy检查,20例进行4D-Hy Co Sy检查,分析图像质量,并分别与造影后腹腔镜下通染液检查结果对照,评价两种造影方法的诊断效能。结果 3D-Hy Co Sy的图像有80.0%(16/20)适于诊断,4D-Hy Co Sy的图像有95.0%(19/20)适于诊断。3D-Hy Co Sy诊断输卵管通畅性的准确率为85.0%,敏感性为90.9%,特异性为77.8%,阳性预测值为83.3%,阴性预测值为87.5%;4D-Hy Co Sy诊断输卵管通畅性的准确率为90.0%,敏感性为95.0%,特异性为85.0%,阳性预测值为86.4%,阴性预测值为94.4%。两种方法与腹腔镜通染液检查结果均有良好的一致性。结论 3D-Hy Co Sy和4D-Hy Co Sy诊断输卵管通畅性均准确可行,但3D-Hy Co Sy图像单一,信息较少,不易诊断,而4D-Hy Co Sy动态直观,信息丰富,易于诊断,因此4D-Hy Co Sy评价输卵管通畅性更具优势。
文摘During the past decades,early fetal ultrasound and diagnosis have increasingly gained attention in pregnancy care with the development of high-frequency transducers,which make it possible to obtain detailed images of the early fetus and its organs,and thus move part of the anatomy and anomaly scan from the second to the first-trimester.By transabdominal sonography or transvaginal sonography,or a combination of both approaches,it is now able to diagnose a wide variety of fetal abnormalities at 11-13^(+6)weeks.
