Different hemodynamic responses by color Doppler ultrasonography studies between sildenafil non-responders and responders

Aim： To determine if there are different penile hemodynamic patterns between sildenafil non-responders and responders by using color Doppler ultrasonography. Methods： A total of 69 erectile dysfunction （ED） patients aged 22-79 years were enrolled into the present study. Thirty-eight （55.1%） men with ED who did not respond to four attempts of treatment with 100 mg sildenafil after re-education were classified as sildenafil non-responders. A com- bination of three vasodilator drugs, 1.25 mg papaverine, 0.4 mg phentolamine and 5 ug prostaglandin E1, was given by intracavernous injection before penile Doppler ultrasonography was carried out. The erectile response to intracavernous injection and vascular parameters including peak systolic velocity （PSV）, resistance index （RI）, end diastolic velocity （EDV） and cavernosa artery diameter （CD） were measured and the results between sildenafil nonresponders and responders were compared. Results： No statistical difference in vascular parameters measured by Doppler ultrasonography studies between non-responders and responders was noted. Sildenafil non-responders had a poorer penile rigidity response to intracavernous injection than responders （P 〈 0.05）. Among patients with adequate PSV （〉 30 cm/s） and abnormal EDV （〉 5 cm/s）, individuals in the non-responder group had fewer positive responses to intracavernous vasodilator injection than in the responder group （35.3% vs. 72.2%, P 〈 0.05）. Advanced age and comorbidity with diabetes mellitus were significantly associated with sildenafil non-response （P 〈 0.05）. Conclusion： Sildenafil non-responders were characterized by a poorer penile rigidity response to intracavernous injection and had an associated impaired veno-occlusive mechanism. Advanced age and comorbidity with diabetes mellitus were two common factors associated with non-response.

Use of color Doppler ultrasonography in the diagnosis of anomalous connection in pancreatobiliary disease

AIM: To estimate the detectability of anomalous connection in pancreatobiliary disease (ACPBD) cases, measuring gallbladder wall blood flow (GWBF).METHODS: In the retrospective study, we enrolled 42subjects with gallbladder wall thickening. GWBF velocity was determined as an average value of the peak velocity of color signals on the gallbladder wall, three times in each case. Based on the findings on endoscopic ultrasonography (EUS) or endoscopic retrograde cholangiopancreatography (ERCP), the 42 subjects were divided into 11 cases with ACPBD and 31 cases without ACPBD. In the prospective study, the subjects were 92 cases with gallbladder wall thickening. Using the cut-off level of the flow velocity obtained in the retrospective study, the usefulness of measuring GWBF velocity in diagnosing ACPBD was evaluated.RESULTS: In the retrospective study, imaging of GWBF was obtained in 40 of the 42 subjects. The mean GWBF velocity of the ACPBD cases was 29.4±3.9 cm/s(mean±SD), which was significantly different (P＜0.0001;95% CI 5.48-13.2) from that of the without ACPBD cases(20.1±5.9 cm/s). Based on this result, we prepared a receiver operating characteristic curve, and the cut-off level appropriate for diagnosing ACPBD was estimated to be 25 cm/s. In the prospective study, GWBF was detected in 86 of the 92 subjects. Based on the EUS or ERCP findings, the 92 subjects were divided into 15 cases with ACPBD and 77 cases without ACPBD. When a cut-off level of 25 cm/s was employed, ACPBD could be diagnosed with a sensitivity of 87.0% (13/15) and a specificity of87.3% (62/71).CONCLUSION: Measurement of GWBF velocity, which is less invasive and provides objective values, is very useful for diagnosing ACPBD prior to the development of malignant tumors in cases with gallbladder wall thickening.

The value of color Doppler ultrasonography in monitoring normal orthotopic liver transplantation and postoperative complications

OBJECTIVE: To assess the value of color Doppler ultrasonography in monitoring normal orthotopic liver transplantation and postoperative complications. METHODS: Forty-one patients after orthotopic liver transplantation were examined by using color Doppler flow imaging to observe the hepatic blood flow and change of ultrasonography of the hepatic parenchyma and bile duct. The measured indexes included maximum blood flow velocity, time-average blood flow velocity (TAV), resistance index (RI) and diameter of the bile duct. RESULTS: Among 41 patients, 17 (41.5%) suffered from liver transplant rejection. Of the 17 patients, 13 (76.4%) showed decrease of TAV of the portal vein, 15 (88.25%) low-amplitude single-phase serrated wave or negative biphasic wave of the hepatic vein, 9 (52.9%) increased hepatic arterial RI, and 5 (29.4%) slightly dilated bile duct. Sonography showed disappearance of the hepatic artery blood flow around the portal vein in 5 (12.2%) of the 41 patients with hepatic artery thrombosis in the postoperative period. Slight dilatation of the intrahepatic bile duct was found in 3 (7.3%) of the 41 patients in the early postoperational period and it normalized within 2 weeks. Ultrasonography of 20 patients (48.8%) revealed a visible dilatation of the intrahepatic bile duct, which was worsening gradually. The causes of bile duct dilatation included biliary stricture in 2 patients (10%), stone in 15 patients (75%) and others in 3 patients (15%). CONCLUSIONS: Color Doppler ultrasonography is valuable for monitoring normal liver transplantation and postoperative complications.

COLOR DOPPLER ULTRASONOGRAPHY APPEARANCES OF RENAL VEIN THROMBOSIS AND ITS DIAGNOSTIC VALUE

Objective To evaluate color Doppler ultrasonography (CDU) appearances of renal vein thrombosis (RVT) and its diagnostic value.Methods Ten patients with RVT were analyzed retrospectively. Renal structure, distributions of intrarenal flow signals, echogenicity, and flow fullness in main renal veins were observed with CDU. Resistance index (RI) was recorded from the waveforms of segmental or interlobar renal artery.Results Ten kidneys in nine patients were confirmed to have thrombus within the main renal veins, and one patient was confirmed to have thrombus within the small intrarenal veins. The appearances of the main renal vein thrombosis included full of solid echogenicity or strip echogenicity and complete or partial filling defect within the main renal veins, and absent or a few intrarenal venous flow signals in 70% of kidneys involved. The appearances of intrarenal vein thrombosis included obscure renal structure and no venous flow signal within the involved part of the kidneys. Reverse diastolic flow in the intrarenal artery had only a sensitivity of 36% (4/11); in other 7 kidneys without intrarenal arterial reverse diastolic flow, increased RI (mean, 0.84; range, 0.74-0.96) was found.Conclusion CDU is helpful for rapid clinical diagnosis and follow-up of RVT, and therefore can be the first imaging modality of choice for RVT.

A study of the hypoechoic hypertrophic lesions and hypoechoic cancer lesions in hypertrophic prostate inner glands with transrectal color doppler ultrasonography

Objective: To observe the sonographic and hemodynamic features of hypoechoic hypertrophic lesions and hypoechoic cancer lesions in the hypertrophic prostate inner glands, in order to raise the accuracy of early diagnosis rate for prostate cancer. Methods: 31 cases of hypoechoic hypertrophic lesions and 18 cases of hypoechoic cancer lesions in the hypertrophic prostate inner glands were observed by transrectal ultrasonography and comparatively analyze the shape, edge and the systolic peak velocity (Vs) , resistance index (RI) and pulsatility index (PI) of the lesions. Results: In contrast with hypertrophic group, the cancer group presented irregular shape and unclear edge, and obviously higher Vs, RI and PI. Conclusion: The sonographic appearance and Vs. RI. PI have important value in distinguishing hypoechoic hypertrophic lesions and hypoechoic cancer lesions in the hypertrophic prostate inner glands.

Value of identifying and diagnosing mammary carcinoma and non-lactation mastitis lump by color Doppler ultrasonography

Objective: To evaluate the value of identifying and diagnosing mammary carcinoma and non-lactation mastitis lump (NLM) by multicolor Doppler ultrasonography. Methods: We compared and analyzed the examination results of 69 cases of mammary carcinoma proved by surgical pathology and 22 cases of NLM before surgery by multicolor Doppler ultra-sonography. Results: The detection rates of mammary carcinoma and NLM focus by ultrasonic examining were 100%. The shape, envelope, foul line, blood stream between sound and image of two diseases were similar. Of the two diseases, the representation with slight calcification in lump, lower echo in low echo, bloodstream distribution and resistance were different. Conclusion: By analyzing the sound and image representation of mammary lump, we find color Doppler ultrasonography has significant value in identifying and diagnosing mammary carcinoma and non-lactation mastitis lump.

Graves' Disease Thyroid Color-Flow Doppler Ultrasonography Assessment: Review Article

Graves’ disease, as known today, is an autoimmune, diffuse, chronic disease of thyroid gland, as described by Robert Graves in 1835. It presents genetic predisposition and unknown etiology evidence, which is influenced in its development by several factors, including environment (dietary iodine intake, stress, drugs and infections). The disease is characterized by one or more changes: hyperthyroidism, goiter, ophthalmopathy, skin changes and pretibial myxedema, around 5% less common, and other symptoms 90% to 95%. One of the most relevant clinical practice aspects in Graves’ disease patients management is to distinguish Graves’ disease in initial phase, from other types of destructive thyrotoxicosis, in addition to evaluate therapeutic methods and efficient follow up, as well as predict early recurrence or remission of disease. Scintigraphy with pertechnetate (99 mTc) and TSH levels dosage are considered the choice for this purpose. However, they present some technical difficulties, as they are not widely available and have contraindications. In this scenario, thyroid color-flow doppler ultrasonography (US Doppler) presents a viable alternative, as a widely available, low cost, non-invasive and radiation free method, providing initial diagnosis and patients with Graves’ disease follow up. In adittion, this method is used in differential diagnosis with other causes of thyrotoxicosis in the early stage.

Color Doppler sonography and angioscintigraphy in hepatic Hodgkin's lymphoma

AIM： To estimate the characteristics of Color Doppler findings and the results of hepatic radionuclide angiography （HRA） in secondary Hodgkin＇s hepatic lymphoma. METHODS： The research included patients with a diagnosis of Hodgkin＇s lymphoma with metastatic focal lesions in the liver and controls. Morphologic characteristics of focal liver lesions and hemodynamic parameters were examined by pulsed and Color Doppler in the portal, hepatic and splenic veins were examined. Hepatic perfusion index （HPI） estimated by HRA was calculated. was observed. Lesions were mostly hypoechoic and mixed, solitary or multiple. Some of the patients presented with dilated splenic veins and hepatofugal blood flow. A pulse wave was registered in the centre and at the margins of lymphoma. The average velocity of the pulse wave was higher at the margins （P 〉 0.05）. A continuous venous wave was found only at the margins of lymphoma. There was no linear correlation between lymphoma size and velocity of pulse and continuous wave （r = 390, P 〈 0.01）. HPI was significantly lower in patients with lymphomas than in controls （P 〈 0.05）, pointing out increased arterial perfusion in comparison to portal perfusion. CONCLUSION： Color Doppler ultrasonography is a sensitive method for the detection of neovascularization in Hodgkin＇s hepatic lymphoma and estimation of its intensity. Hepatic radionuclide angiography can additionally help in the assesment of vascularisation of liver lesions.

Prospective Study of Color Doppler Ultrasonography in the Diagnosis of Breast Disease.

One hundred and four cases of breast disease were examined by color Doppler ultrasonography (CDUS). Malignant lesions were rich in blood blow signal and 56% of +++-++++grade while benign lesions had little blood flow signal

Radiation induced renal arterial stenosis detected by color duplex ultrasonography: case report

Renal artery stenosis as a complication from radiation therapy is not common, but it is life threatening and needs to be corrected urgently in order to prevent renal failure even losing kidney. The diagnostic criteria of renal artery stenosis in the adults by color duplex ultrasonography have been established, which may play an important role in screening radiation induced renal artery stenosis.

Laparoscopic splenectomy： color Doppler flow imaging for preoperative evaluation

Background Laparoscopic splenectomy （LS） is currently the standard approach for resection of a normal-sized spleen. However, this method becomes technical challenge in cases of splenomegaly due to intraoperative hemorrhage. A complete understanding of the splenic vessel anatomy is important to facilitate the difficult laparoscopic procedure. In this retrospective study, we examined the role of color Doppler flow imaging （CDFI） in splenic vessel anatomy and evaluated its value for LS. Methods Forty-eight patients who underwent splenectomy for various hematologic and autoimmune disorders from May 2004 to December 2007 were enrolled in this study. Twenty-three patients underwent preoperative CDFI examination that included examination of the anatomic type of splenic pedicle, the adjacent relationship between the splenic vessel and pancreas, and spleen size （CDFI group）. In the remaining 25 patients, ultrasonic inspections of the splenic vessel were not performed （non-CDFI group）. Laparoscopic splenectomies in the CDFI group were performed in accordance with the information provided by the preoperative CDFI in each patient. In the non-CDFI group, LS was performed according to the conventional method. In the CDFI group, the constituent ratios of the above-mentioned parameters by CDFI were compared with those recorded during LS using the chi square test. The effectiveness of the technique on surgery in both groups was compared with an independent sample Student＇s ttest. Results All laparoscopic splenectomies in both groups were performed successfully. However, 2 cases in the non-CDFI group were converted to LS with the assistance of micro-incision because the branches of the splenic vein were inadvertently torn. Two anatomic types of splenic pedicle and four different adjacent relationships between the splenic vessel and pancreas were detected by CDFI. About 80% of spleens fit the criteria of megalosplenia. There were no statistically significant differences between the constituent ratios of the parameters by CDFI and those by intraoperative telerecording in the CDFI group （χ^2=0.383, 1.072, 0.119, P=0.536, 0.784, 0.730）. However, statistically significant differences were observed in the operative time （（158.70±42.51） minutes vs （200.65±47.89） minutes, P=0.003）, intraoperative blood loss （（55.87±17.36） ml vs （101.83±62.21） ml, P=0.001）, and recovery time of gastrointestinal function （（24.39±8.88） hours vs （30.60±9.45） hours, P=0.024） between the groups. Conclusions The individual operative route and schedule can be successfully determined on the basis of various kinds of reproducible anatomic frameworks of the spleen provided by preoperative CDFI. This technique facilitates the surgical procedure, shortens the operative time, reduces intraoperative blood loss and decreases the risk of LS in splenomegaly cases.

Portalsystemic hemodynamic changes in chronic severe hepatitis B: An ultrasonographic study

AIM： To evaluate portalsystemic hemodynamic changes in chronic severe hepatitis B. METHODS： Hemodynamic parameters included portal vein diameter （PVD）, portal vein peak velocity （PVPV）, portal vein volume （PW）, spleen length （SPL）, spleen vein diameter （SPVD）, spleen vein volume （SPW） and umbilical vein recanalization. They were measured by Color Doppler ultrasonography in 36 patients with chronic severe hepatitis B, compared with 51 normal controls, 61 patients with chronic hepatitis B, 46 patients with compensable cirrhosis, and 36 patients with decompensable cirrhosis. RESULTS： In the group of chronic severe hepatitis B, PVD （12.38 ± 1.23 mm） was significantly different from the normal control, compensable cirrhosis and decompensable cirrhosis groups （P = 0.000-0.026）, but not significantly different from the chronic hepatitis group. PVPV （16.15 ± 3.82 cm/s） dropped more significantly in the chronic severe hepatitis B group than the normal control, chronic hepatitis B and compensable cirrhosis groups （P = 0.000-0.011）. PW （667.53 ± 192.83 mL/min） dropped significantly as compared with the four comparison groups （P = 0.000-0.004）. SPL （120.42 ± 18.36 mm） and SPVD （7.52 ± 1.52 mm） were longer in the normal control and chronic hepatitis B groups （P = 0.000-0.009）, yet they were significantly shorter than those in the decompensable cirrhosis group （P = 0.000）. SPW （242.51 ± 137.70 mL/min） was also lower than the decompensable cirrhosis group （P = 0.000）. The umbilical vein recanalization rate （75%） was higher than the chronic hepatitis B and compensable cirrhosis groups. In the course of progression from chronic hepatitis to decompensable cirrhosis, PVD, SPL and SPVD gradually increased and showed significant differences between every two groups （P = 0.000-0.002）. CONCLUSION： Patients with chronic severe hepatitis B have a tendency to develop acute portal hypertension, resulting in significantly reduced portal vein perfusion, Observation of the portalsystemic hemodynamic changes may be contributed to the disease progression of chronic liver disease.

18 MHz彩色多普勒超声检查对黄斑前膜的临床诊断价值

目的:探讨18 MHz彩色多普勒超声对黄斑前膜的诊断价值。方法:收集2020-01/2022-01期间在我院经眼底检查拟诊白内障和玻璃体混浊的患者44例80眼,分别通过光学相干断层扫描法(OCT)与18 MHz彩色多普勒超声对患眼进行检查,比较18 MHz彩色多普勒超声与OCT对黄斑前膜诊断敏感度、特异性、准确度的差异。结果:经18 MHz彩色多普勒超声检测80眼中,62眼为黄斑前膜,18眼为非黄斑前膜;经OCT确诊确实为黄斑前膜的54眼,非黄斑前膜的13眼,漏诊5眼,误诊8眼;18 MHz彩色多普勒超声与OCT诊断一致性较高(Kappa=0.892,P<0.05);18 MHz彩色多普勒超声检测黄斑前膜敏感性为92%,特异性为62%,漏诊率为8%,误诊率为38%,正确率为84%;与OCT检测相比,18 MHz彩色多普勒超声检测特异性、正确率、阳性预测准确率、阴性预测准确率降低,误诊率升高(均P<0.05),诊断敏感性与漏诊率比较无差异(均P>0.05)。结论:18 MHz彩色多普勒超声对黄斑前膜病变具有一定鉴定价值,与OCT检验具有一致性。

基于超声纹理特征与基于超声造影的预测模型鉴别最大径≤2 cm乳腺良恶性结节的对比研究

目的比较基于二维超声纹理特征(2D-Ultrasomics)的预测模型与基于超声造影(CEUS)的预测模型鉴别最大径≤2 cm乳腺良恶性结节的诊断价值。方法选取我院经病理确诊的乳腺结节患者109例(共112个结节),依据病理结果分为良性组58个和恶性组54个,均行二维超声及彩色多普勒(2D-CDUS)、CEUS检查,比较两组超声检查结果的差异;基于二维超声图像提取2D-Ultrasomics,使用最小绝对收缩和选择算子(LASSO)进行特征筛选。采用多因素Logistic回归分别构建2D-CDUS模型、2D-CDUS结合CEUS(2D-CD+CEUS)模型、2D-CDUS结合2D-Ultrasomics(2DCDUS+Ultrasomics)模型,绘制受试者工作特征(ROC)曲线评估各模型鉴别最大径≤2 cm乳腺良恶性结节的诊断效能;采用Hosmer-Lemeshow拟合优度检验评估模型的拟合度;绘制临床决策曲线评估模型的临床适用性。结果两组结节2D-CDUS图像特征(内部回声、边界、血流、短径)和CEUS图像特征(增强方式、增强时相、造影边界、增强均匀性、增强病灶范围)比较差异均有统计学意义(均P<0.05)。共提取818个2D-Ultrasomics,经过LASSO筛选后保留6个关键特征。根据多因素Logistic回归分析结果,纳入边界、短径构建2D-CDUS模型,纳入边界、短径、造影边界构建2D-CD+CEUS模型,纳入短径、灰度游程长度矩阵、灰度依赖矩阵、灰度大小区矩阵构建2D-CDUS+Ultrasomics模型。ROC曲线分析显示,2D-CDUS+Ultrasomics模型鉴别最大径≤2 cm乳腺良恶性结节的曲线下面积(AUC)为0.917,高于2D-CD+CEUS模型、2D-CDUS模型的AUC(0.892、0.823),且2D-CD+CEUS模型的AUC高于2D-CDUS模型的AUC,差异均有统计学意义(均P<0.001)。Hosmer-Lemeshow拟合优度检验显示,2D-CDUS模型、2D-CD+CEUS模型和2D-CDUS+Ultrasomics模型均具有良好的拟合度(P=0.818、0.103、0.281)。临床决策曲线分析显示,2D-CDUS+Ultrasomics模型在0.20~0.39、0.43~0.78及0.88~0.91概率阈值范围内具有较高的临床获益。结论基于2D-Ultrasomics的预测模型较基于CEUS的预测模型能更准确地鉴别最大径≤2 cm乳腺良恶性结节,有助于临床早期准确诊断乳腺小结节和制定治疗决策。

下肢动脉硬化闭塞症临床误诊分析

目的分析下肢动脉硬化闭塞症的临床误诊原因,以提高临床医师诊治水平。方法回顾性分析2022年1月至2024年1月收治的曾误诊的2例下肢动脉硬化闭塞症患者的临床资料。结果1例因右小腿麻木、间歇性跛行、右足趾、小腿持续性疼痛、右足趾末端感觉消失,多次就诊于当地医院诊断为血栓闭塞性脉管炎,予相应治疗症状未见缓解反而加重,后经彩色多普勒超声检查确诊为右股动脉硬化性闭塞症。误诊时间3年。确诊后予相应治疗后坏疽停止进展,行人工血管移植转流和右侧前足截除术。术后3个月随访,症状消失,胫后动脉和足背动脉搏动恢复。1例右下肢间歇性跛行,伴下腰部疼痛不适,行腰椎CT检查考虑腰椎间盘突出症,予相应治疗后,间歇性跛行症状进行性加重并出现右膝下皮肤溃烂坏死,行右下肢动脉造影术,术中见右侧髂总动脉及髂外动脉闭塞,诊断为下肢动脉硬化闭塞症。误诊时间1年。确诊后行血管腔内支架成形术,右股动脉及右足背动脉搏动恢复。术后1个月复查无下肢不适症状。结论下肢动脉硬化闭塞症早期表现多样,误诊率较高,医师应提高对该病的认识,认真详细询问病史及查体,重视临床资料的综合分析,早期行特异性检查方法,以降低误诊率。

SWE成像技术联合血流灌注参数Peak、Tp、MTT对甲状腺良恶性结节的诊断价值

目的:探究实时剪切波弹性成像(SWE)技术联合超声造影(CEUS)对甲状腺良恶性结节的诊断价值。方法:选取我院2017年1月—2019年1月甲状腺恶性结节患者72例(101个结节)作为恶性组,甲状腺良性结节患者72例(98个结节)作为良性组,均行SWE、CEUS检查,以手术病理诊断结果作为“金标准”,比较两组SWE成像参数(弹性模量最大值(E_(max))、弹性模量最小值(E_(min))、弹性模量平均值(E_(mean)))、CEUS血流灌注参数(峰值强度(Peak)、达峰时间(Tp)、平均通过时间(MTT)),评价SWE成像参数与Peak、Tp、MTT相关性,并评价各参数对甲状腺良恶性结节诊断的价值,对比恶性组与良性组不同大小结节患者SWE成像参数、CEUS血流灌注参数,探究各参数对不同大小甲状腺良恶性结节的诊断价值。结果:恶性组E_(max)、E_(min)、E_(mean)、Tp、MTT高于良性组,Peak低于良性组(P<0.05);E_(max)、E_(min)、E_(mean)与Tp、MTT呈正相关,与Peak呈负相关(P<0.05);SWE成像参数、CEUS血流灌注参数联合鉴别诊断甲状腺良恶性结节的AUC大于各指标单一鉴别诊断,为0.884,最佳诊断敏感度、特异度分别为86.27%、81.63%;恶性组结节>10 mm患者E_(max)、E_(min)、E_(mean)、Tp、MTT高于结节≤10 mm患者,Peak低于结节≤10 mm患者(P<0.05);SWE成像参数、CEUS血流灌注参数联合诊断>10 mm甲状腺结节良恶性的AUC大于单一诊断,为0.880,最佳诊断敏感度、特异度分别为85.19%、76.74%;SWE成像参数、CEUS血流灌注参数联合诊断≤10 mm甲状腺结节良恶性的AUC大于单一诊断,为0.873,最佳诊断敏感度、特异度分别为78.72%、85.45%。结论:SWE成像参数,CEUS血流灌注参数Peak、Tp、MTT联合在甲状腺结节良恶性鉴别诊断方面具有较高应用价值,但其鉴别诊断≤10 mm和>10 mm甲状腺结节良恶性的截断值不同,临床应用中应加以区分。

彩色多普勒超声检查颈动脉IMT及斑块在老年缺血性脑卒中患者中的应用价值

目的彩色多普勒超声检查颈动脉IMT及斑块在老年缺血性脑卒中患者中的应用价值。方法本研究选取2015年7月~2016年12月河北省承德市宽城满族自治县医院收治的64例首发缺血性脑卒中老年患者作为观察组,并选择同期64例门诊健康老年体检者为对照组。测量血管内径、内-中膜厚度(IMT),记录斑块部位、范围、数量及管腔狭窄情况,并进行两组间比较。结果观察组双侧颈总动脉、颈动脉球部、颈内动脉的IMT均明显厚于对照组(P<0.05)。对照组同部位左右两侧IMT无明显差异(P>0.05),而观察组左侧IMT均明显厚于右侧同部位IMT,差异显著有统计学意义(t_(颈总)=5.18,P<0.05;t_(球部)=5.43,P<0.05;t_(颈内)=5.86,P<0.05)。与对照组比较,观察组IMT增厚、斑块及管腔狭窄发生率均明显增加(84.38%vs33.13%、79.68%vs14.06%、33.13%vs10.94%),差异有统计学意义(P<0.05)。随着年龄的增长,管腔狭窄比例明显升高,差异有统计学意义(χ~2=8.17,P<0.05)。结论彩色多普勒超声检查具有无创、可重复性的优势,能够清楚的显示颈动脉中的斑块位置以及范围,对于高龄患者发生缺血性脑卒中发生的防控具有重要的意义。

TVS三步法系统超声评估深部子宫内膜异位症的价值初探

目的:应用经阴道超声(TVS)三步法系统超声评估深部子宫内膜异位症(DIE)的诊断价值。方法:57例疑似DIE患者在我院接受手术。所有患者在手术前接受TVS三步法系统超声评估,术前详细询问病史、准确记录病灶的部位、大小及特征性超声表现,将结果与手术和(或)组织学进行对照。结果:根据病变发生部位、大小的不同,TVS三步法系统超声评估DIE的敏感度为55.3%~99.7%,特异度为84.7%~96.6%。结论:TVS三步法在检测DIE的位置、范围及深度方面具有价值,有助于在术前对DIE患者进行全面评估。

脂肪肉瘤的超声图像特征分析

目的 分析并总结脂肪肉瘤的超声图像特征。方法 回顾性分析我院经手术病理证实的31例脂肪肉瘤患者的超声资料,分析不同病理亚型的脂肪肉瘤超声图像特征。结果 31例患者中,去分化脂肪肉瘤13例,高分化脂肪肉瘤10例,多形性脂肪肉瘤4例,黏液样脂肪肉瘤4例;肿瘤最大径为(16.97±9.70)cm,以等或高回声(61.3%,19/31)为主,且回声分布多不均匀(90.3%,28/31),CDFI多表现为乏血供,Adler血流分级以0、Ⅰ级为主(96.8%,30/31)。其中,高分化脂肪肉瘤以高回声为主(70.0%,7/10);去分化脂肪肉瘤边界多不清晰(92.3%,12/13),以低回声(46.2%,6/13)和高回声(30.8%,4/13)的双相模式为主;多形性脂肪肉瘤边界多清晰(3/4);黏液样脂肪肉瘤CDFI均表现为极度乏血供(4/4)。结论 脂肪肉瘤的超声表现具有一定的特征性,对临床辅助诊断该病能够提供一定的帮助。

超声造影评估无症状性ICA重度狭窄患者CAS术后脑灌注改变的研究

目的:应用超声造影评估无症状性颈内动脉(ICA)重度狭窄患者行颈动脉支架置入术(CAS)后的脑灌注改变的价值。方法:选取2020年7月-2022年12月我院行CAS术的单侧ICA重度狭窄患者18例,男14例,女4例,平均年龄(62.6±7.3)岁。患者无临床症状或仅表现为轻度头痛、头晕。分别于CAS术前、术后12 h内行双侧经颅超声造影检查,选取基底节区作为感兴趣区(ROI)进行时间-强度曲线分析,测量参数为达峰时间(TTP),平均通过时间(MTT),上升斜率(WIS),峰值强度(PI),曲线下面积(AUC),计算患侧与健侧参数的相对值rTTP,rMTT,rWIS,rPI,rAUC,及CAS术后改变量ΔrTTP,ΔrMTT,Δr WIS,Δr PI,ΔrAUC。比较CAS术前、术后参数绝对值与相对值,并对CAS术前相对值与术后改变量的相关性进行分析。结果:CAS术前,患侧TTP(22.17±3.34) s,MTT (33.73±5.88) s均较健侧延长,WIS (1.75±0.68) dB/s低于健侧(P<0.05),而PI,AUC双侧比较无统计学差异;CAS术后,患侧参数绝对值仅WIS (2.14±0.69) dB/s较术前增高(P<0.05);相对值rTTP (1.02±0.08),r MTT(0.96±0.10)低于术前,rWIS (1.02±0.17)较术前增高(P<0.05);CAS术前相对值rTTP,rMTT,rWIS分别与术后改变量ΔrTTP,Δr MTT,ΔrWIS存在负相关关系(r值分别为-0.592,-0.754及-0.730)。结论:超声造影可评估无症状性ICA重度狭窄患者CAS术后脑灌注的改变,术后双侧灌注差异性降低,且患侧术前脑灌注受损程度越重,术后改善越明显。