We demonstrate the possibility of detection and monitoring of bubbles emerging near the tip of an optical fiber by means of ultrasonic method.The excitation of bubbles at their resonant frequencies is performed using ...We demonstrate the possibility of detection and monitoring of bubbles emerging near the tip of an optical fiber by means of ultrasonic method.The excitation of bubbles at their resonant frequencies is performed using short ultrasonic pulses having a wide frequency range simulta-neously with their modulation by means of a long pulse of a monochromatic frequency.This method allows detection of bubbles of various sizes.Used signal processing method,which allows increased bubble detection accuracy,is proposed for ressearch in envir onments of biological-like medium which show continuous variations in structure and properties when exposed to optical emission.The method has been demonstrated on model objects:in a liquid and in a biological tissue phantom using various methods of bubble generation(hydrolysis and optical enission).We studied bubble formation by the tip of a fiber of the surgical laser LSP-007/10 "IRE Polus"with a wavelength of 0.97μm coated with a highly absorbing graphite layer.展开更多
The field of acousto-optical tomography （AOT） for medical applications began in the 1990s and has since developed multiple techniques for the detection of ultrasound-modulated light. Light becomes frequency shifted ...The field of acousto-optical tomography （AOT） for medical applications began in the 1990s and has since developed multiple techniques for the detection of ultrasound-modulated light. Light becomes frequency shifted as it travels through an ultrasound beam. This ＂tagged＂ light can be detected and used for focused optical imaging. Here, we present a comprehensive overview of the techniques that have developed since around 2011 in the field of biomedical AOT. This includes how AOT has advanced by taken advantage of the research conducted in the ultrasound, as well as, the optical fields. Also, simulations and reconstruction algorithms have been formulated specifically for AOT imaging over this time period. Future progression of AOT relies on its ability to provide significant contributions to in vivo imaging for biomedical applications. We outline the challenges that AOT still faces to make in vivo imaging possible and what has been accomplished thus far, as well as possible future directions.展开更多
基金financial support from grant 14-15-00840 of the Russian Scientific Fund.
文摘We demonstrate the possibility of detection and monitoring of bubbles emerging near the tip of an optical fiber by means of ultrasonic method.The excitation of bubbles at their resonant frequencies is performed using short ultrasonic pulses having a wide frequency range simulta-neously with their modulation by means of a long pulse of a monochromatic frequency.This method allows detection of bubbles of various sizes.Used signal processing method,which allows increased bubble detection accuracy,is proposed for ressearch in envir onments of biological-like medium which show continuous variations in structure and properties when exposed to optical emission.The method has been demonstrated on model objects:in a liquid and in a biological tissue phantom using various methods of bubble generation(hydrolysis and optical enission).We studied bubble formation by the tip of a fiber of the surgical laser LSP-007/10 "IRE Polus"with a wavelength of 0.97μm coated with a highly absorbing graphite layer.
文摘The field of acousto-optical tomography （AOT） for medical applications began in the 1990s and has since developed multiple techniques for the detection of ultrasound-modulated light. Light becomes frequency shifted as it travels through an ultrasound beam. This ＂tagged＂ light can be detected and used for focused optical imaging. Here, we present a comprehensive overview of the techniques that have developed since around 2011 in the field of biomedical AOT. This includes how AOT has advanced by taken advantage of the research conducted in the ultrasound, as well as, the optical fields. Also, simulations and reconstruction algorithms have been formulated specifically for AOT imaging over this time period. Future progression of AOT relies on its ability to provide significant contributions to in vivo imaging for biomedical applications. We outline the challenges that AOT still faces to make in vivo imaging possible and what has been accomplished thus far, as well as possible future directions.
