Purpose : To compare the clinical application value of Ultrasound biomicrsocpic dark room provocative test with the traditional dark room test in screening primary angle closure glaucoma (PACG).Methods: 22 eyes with P...Purpose : To compare the clinical application value of Ultrasound biomicrsocpic dark room provocative test with the traditional dark room test in screening primary angle closure glaucoma (PACG).Methods: 22 eyes with PACG in prodromal stage and 30 eyes with deep anterior chamber and wide angle of 15 normal persons were observed in this trail. All 52 eyes were performed traditional dark room provocative test and ultrasound biomicorosopic darkroom test respectively. With different positive diagnostic criteria, the sensitivity of the two methods were compared using chi-squared analysis.Results : After staying in the dark room for 2 hours, In case group, IOP in 10 of 22 eyes rose more than 1. 07kPa(1kPa = 7.5mmHg), in 12 eyes less than 1.07kPa or had no changes; appositional angle closure were found by Goldmann gonioscopy in 8 eyes : 3 eyes in two quadrants, 5 eyes in more than two quadrants; the appositional angle closure was found by UBM in 15 eyes; 3 eyes in one quadrants, 5 eyes in two quadrants, 7展开更多
Endoscopic ultrasound(EUS) has become a well accepted test for the diagnosis of chronic pancreatitis.Advantages include its ability to detect subtle and severe changes of the pancreatic duct and parenchyma,and its rel...Endoscopic ultrasound(EUS) has become a well accepted test for the diagnosis of chronic pancreatitis.Advantages include its ability to detect subtle and severe changes of the pancreatic duct and parenchyma,and its relative safety compared with endoscopic retrograde cholangiopancreatography.Limitations include inter-and intraobserver variability,operator dependence,and an incomplete understanding of its true accuracy.The Rosemont classif ication has recently been proposed as a weighted,standardized method that may improve EUS chronic pancreatitis scoring.This paper reviews the published evidence regarding the accuracy of EUS in chronic pancreatitis diagnosis,and enumerates the emerging technologies that have been recently studied which may ultimately improve endosonographic imaging of the pancreas.展开更多
Background and Aim: Visceral leishmaniasis (VL), also known as kala azar, is a parasitic disease that caused by infection with Leishmania parasites, which are spread by the bite of phlebotomine sand flies. An ultrasou...Background and Aim: Visceral leishmaniasis (VL), also known as kala azar, is a parasitic disease that caused by infection with Leishmania parasites, which are spread by the bite of phlebotomine sand flies. An ultrasound examination is strongly advocated for the promote diagnosis and treatment of VL for long term follow up and evaluation of unresponsive cases. The aim of this study was to assess the consequences of VL in the liver, spleen and pancreas of affected participants by using ultrasound. Materials and Methods: A prospective cohort study was conducted in the period of January 2012 to March 2014 in the ultrasound department of Tropical Disease Hospital (TDH) in Khartoum-Sudan, among a group of 100 participants (84% males, 16% females and their ages ranges from 15 to 45 years) positive to VL and had been diagnosed by laboratory tests;either serological or Napier’s Aldehyde test. The Aloka portable ultrasound machine equipped with 3.5 MHz convex probe was used for abdominal ultrasound scanning. Standard Statistical Package for the Social Sciences (SPSS) was used to analyze the results. Results: The commonest ultrasound findings in VL participants were hepatomegaly (100%), splenomegaly (100%) and ascites (50%). Other complications such as lymphadenopathy (35%), focal splenic lesions (34%), dilated portal vein (7%) and shrinkage liver (4%) were detected. Conclusion: Ultrasound scanning presents an effective role in VL, because of its ability to detect the consequences of this disease in various abdominal organs such as liver, spleen and pancreas earlier, which in turn allowing the possibility to treat these complications and prevents the deterioration of a patient’s health status.展开更多
BACKGROUND Carcinoembryonic antigen(CEA)and cytology in pancreatic cystic fluid are suboptimal for evaluation of pancreatic cystic neoplasms.Genetic testing and microforceps biopsy are promising tools for pre-operativ...BACKGROUND Carcinoembryonic antigen(CEA)and cytology in pancreatic cystic fluid are suboptimal for evaluation of pancreatic cystic neoplasms.Genetic testing and microforceps biopsy are promising tools for pre-operative diagnostic improvement but comparative performance of both methods is unknown.AIM To compare the accuracy of genetic testing and microforceps biopsy in pancreatic cysts referred for surgery.METHODS We performed a literature search in Medline,Scopus,and Web of Science for studies evaluating genetic testing of cystic fluid and microforceps biopsy of pancreatic cysts,with endoscopic ultrasound with fine-needle aspiration(EUSFNA)prior to surgery and surgical pathology as reference standard for diagnosis.We evaluated the diagnostic accuracy for:1-benign cysts;2-mucinous low-risk cysts;3-high-risk cysts,and the diagnostic yield and rate of correctly identified cysts with microforceps biopsy and molecular analysis.We also assessed publication bias,heterogeneity,and study quality.RESULTS Eight studies,including 1206 patients,of which 203(17%)referred for surgery who met the inclusion criteria were analyzed in the systematic review,and seven studies were included in the meta-analysis.Genetic testing and microforceps biopsies were identical for diagnosis of benign cysts.Molecular analysis was superior for diagnosis of both low and high-risk mucinous cysts,with sensitivities of 0.89(95%CI:0.79-0.95)and 0.57(95%CI:0.42-0.71),specificities of 0.88(95%CI:0.75-0.95)and 0.88(95%CI:0.80-0.93)and AUC of 0.9555 and 0.92,respectively.The diagnostic yield was higher in microforceps biopsies than in genetic analysis(0.73 vs 0.54,respectively)but the rates of correctly identified cysts were identical(0.73 with 95%CI:0.62-0.82 vs 0.71 with 95%CI:0.49-0.86,respectively).CONCLUSION Genetic testing and microforceps biopsies are useful second tests,with identical results in benign pancreatic cysts.Genetic analysis performs better for low-and high-risk cysts but has lower diagnostic yield.展开更多
基于信息可视化分析,对非线性超声的研究现状进行分析。检索Web of Science数据库,得到非线性超声相关文献4061篇。对关键词进行可视化分析及聚类分析,非线性超声领域关键词主要涉及6个方面,目前主要侧重于理论研究。对于应用范围,在微...基于信息可视化分析,对非线性超声的研究现状进行分析。检索Web of Science数据库,得到非线性超声相关文献4061篇。对关键词进行可视化分析及聚类分析,非线性超声领域关键词主要涉及6个方面,目前主要侧重于理论研究。对于应用范围,在微裂纹、结构监测等方面具有应用前景。对非线性超声的论文数及专利数进行技术成熟度分析,结果表明其处在技术发展的增长期。展开更多
文摘Purpose : To compare the clinical application value of Ultrasound biomicrsocpic dark room provocative test with the traditional dark room test in screening primary angle closure glaucoma (PACG).Methods: 22 eyes with PACG in prodromal stage and 30 eyes with deep anterior chamber and wide angle of 15 normal persons were observed in this trail. All 52 eyes were performed traditional dark room provocative test and ultrasound biomicorosopic darkroom test respectively. With different positive diagnostic criteria, the sensitivity of the two methods were compared using chi-squared analysis.Results : After staying in the dark room for 2 hours, In case group, IOP in 10 of 22 eyes rose more than 1. 07kPa(1kPa = 7.5mmHg), in 12 eyes less than 1.07kPa or had no changes; appositional angle closure were found by Goldmann gonioscopy in 8 eyes : 3 eyes in two quadrants, 5 eyes in more than two quadrants; the appositional angle closure was found by UBM in 15 eyes; 3 eyes in one quadrants, 5 eyes in two quadrants, 7
文摘Endoscopic ultrasound(EUS) has become a well accepted test for the diagnosis of chronic pancreatitis.Advantages include its ability to detect subtle and severe changes of the pancreatic duct and parenchyma,and its relative safety compared with endoscopic retrograde cholangiopancreatography.Limitations include inter-and intraobserver variability,operator dependence,and an incomplete understanding of its true accuracy.The Rosemont classif ication has recently been proposed as a weighted,standardized method that may improve EUS chronic pancreatitis scoring.This paper reviews the published evidence regarding the accuracy of EUS in chronic pancreatitis diagnosis,and enumerates the emerging technologies that have been recently studied which may ultimately improve endosonographic imaging of the pancreas.
文摘Background and Aim: Visceral leishmaniasis (VL), also known as kala azar, is a parasitic disease that caused by infection with Leishmania parasites, which are spread by the bite of phlebotomine sand flies. An ultrasound examination is strongly advocated for the promote diagnosis and treatment of VL for long term follow up and evaluation of unresponsive cases. The aim of this study was to assess the consequences of VL in the liver, spleen and pancreas of affected participants by using ultrasound. Materials and Methods: A prospective cohort study was conducted in the period of January 2012 to March 2014 in the ultrasound department of Tropical Disease Hospital (TDH) in Khartoum-Sudan, among a group of 100 participants (84% males, 16% females and their ages ranges from 15 to 45 years) positive to VL and had been diagnosed by laboratory tests;either serological or Napier’s Aldehyde test. The Aloka portable ultrasound machine equipped with 3.5 MHz convex probe was used for abdominal ultrasound scanning. Standard Statistical Package for the Social Sciences (SPSS) was used to analyze the results. Results: The commonest ultrasound findings in VL participants were hepatomegaly (100%), splenomegaly (100%) and ascites (50%). Other complications such as lymphadenopathy (35%), focal splenic lesions (34%), dilated portal vein (7%) and shrinkage liver (4%) were detected. Conclusion: Ultrasound scanning presents an effective role in VL, because of its ability to detect the consequences of this disease in various abdominal organs such as liver, spleen and pancreas earlier, which in turn allowing the possibility to treat these complications and prevents the deterioration of a patient’s health status.
文摘BACKGROUND Carcinoembryonic antigen(CEA)and cytology in pancreatic cystic fluid are suboptimal for evaluation of pancreatic cystic neoplasms.Genetic testing and microforceps biopsy are promising tools for pre-operative diagnostic improvement but comparative performance of both methods is unknown.AIM To compare the accuracy of genetic testing and microforceps biopsy in pancreatic cysts referred for surgery.METHODS We performed a literature search in Medline,Scopus,and Web of Science for studies evaluating genetic testing of cystic fluid and microforceps biopsy of pancreatic cysts,with endoscopic ultrasound with fine-needle aspiration(EUSFNA)prior to surgery and surgical pathology as reference standard for diagnosis.We evaluated the diagnostic accuracy for:1-benign cysts;2-mucinous low-risk cysts;3-high-risk cysts,and the diagnostic yield and rate of correctly identified cysts with microforceps biopsy and molecular analysis.We also assessed publication bias,heterogeneity,and study quality.RESULTS Eight studies,including 1206 patients,of which 203(17%)referred for surgery who met the inclusion criteria were analyzed in the systematic review,and seven studies were included in the meta-analysis.Genetic testing and microforceps biopsies were identical for diagnosis of benign cysts.Molecular analysis was superior for diagnosis of both low and high-risk mucinous cysts,with sensitivities of 0.89(95%CI:0.79-0.95)and 0.57(95%CI:0.42-0.71),specificities of 0.88(95%CI:0.75-0.95)and 0.88(95%CI:0.80-0.93)and AUC of 0.9555 and 0.92,respectively.The diagnostic yield was higher in microforceps biopsies than in genetic analysis(0.73 vs 0.54,respectively)but the rates of correctly identified cysts were identical(0.73 with 95%CI:0.62-0.82 vs 0.71 with 95%CI:0.49-0.86,respectively).CONCLUSION Genetic testing and microforceps biopsies are useful second tests,with identical results in benign pancreatic cysts.Genetic analysis performs better for low-and high-risk cysts but has lower diagnostic yield.
文摘基于信息可视化分析,对非线性超声的研究现状进行分析。检索Web of Science数据库,得到非线性超声相关文献4061篇。对关键词进行可视化分析及聚类分析,非线性超声领域关键词主要涉及6个方面,目前主要侧重于理论研究。对于应用范围,在微裂纹、结构监测等方面具有应用前景。对非线性超声的论文数及专利数进行技术成熟度分析,结果表明其处在技术发展的增长期。
