Abrupt near-surface temperature changes in mountainous areas are a special component of the mountain climate system.Fast and accurate measurements of the locations,intensity,and width of the near-surface changes are n...Abrupt near-surface temperature changes in mountainous areas are a special component of the mountain climate system.Fast and accurate measurements of the locations,intensity,and width of the near-surface changes are necessary but highly difficult due to the complicated environmental conditions and instrumental issues.This paper develops a spatial pattern recognition method to measure the near-surface high temperature increase(NSHTI),one of the lesser-attended changes.First,raster window measurement was proposed to calculate the temperature lapse rate using MODIS land surface temperature and SRTM DEM data.It fully considers the terrain heights of two neighboring cells on opposite or adjacent slopes with a moving window of 3×3 cell size.Second,a threshold selection was performed to identify the NSHTI cells using a threshold of-0.65℃/100 m.Then,the NSHTI strips were parameterized through raster vectorization and spatial analysis.Taking Yunnan,a mountainous province in southwestern China,as the study area,the results indicate that the NSHTI cells concentrate in a strip-like pattern along the mountains and valleys,and the strips are almost parallel to the altitude contours with a slight northward uplift.Also,they are located mostly at a 3/5 height of high mountains or within 400 m from the valley floors,where the controlling topographic index is the altitude of the terrain trend surface but not the absolute elevation and the topographic uplift height and cutting depth.Additionally,the NSHTI intensity varies with the geographic locations and the proportions increase with an exponential trend,and the horizontal width has a mean of about 1000 m and a maximum of over 5000 m.The result demonstrates that the proposed method can effectively recognize NSHTI boundaries over mountains,providing support for the modeling of weather and climate systems and the development of mountain resources.展开更多
Several notable issues arise from overcrowding in an emergency department (ED) for both patients and staff. Longer wait times, higher ambulance diversion rates, longer stays, higher incidence of medical errors, higher...Several notable issues arise from overcrowding in an emergency department (ED) for both patients and staff. Longer wait times, higher ambulance diversion rates, longer stays, higher incidence of medical errors, higher rates of patient mortality, and greater harm to hospitals due to financial losses are some of these problems. Collaboration is crucial in the healthcare industry since it determines the team’s hourly performance in managing patient care. By using Walker and Avant’s (2011) concept analysis method, the author reviewed the literature to better understand ED crowding, to ensure that patients receive safe treatment in a timely manner, and to highlight best practices that can be identified through concept analysis and practice evaluations. In conducting this concept analysis, Walker and Avant’s framework was applied to examine the nature of the findings selected for the advancement of the concept. Everyone working in the ED, from those who determine policy to those on the front lines continually encounter new obstacles, but has little or no time to formulate fresh concepts or reconsider how ED treatment is provided. Overcrowding occurs when the number of patients requiring attention, awaiting transfer, or undergoing diagnosis and treatment exceeds the physical capacity of ED staff. If a clear plan is not in place to increase and improve services in proportion to a growing population, this situation will persist.展开更多
Background: In recent years, we have established an entry-level Forward Surgical Team (FST) training program in a Chinese military medical university for the 5th grade undergraduates, who would be deployed to differen...Background: In recent years, we have established an entry-level Forward Surgical Team (FST) training program in a Chinese military medical university for the 5th grade undergraduates, who would be deployed to different military medical services as primary combat surgeons. This study aimed to assess the role of this pre-service training in improving their confidence with combat medical skills, after several years since they received the training. Methods: We conducted a nationwide survey of 239 primary combat surgeons who have ever participated in an entry-level FST training program before deployment between June 2016 and June 2020, which was for evaluating on a 5-point Likert scale the benefits of entry-level FST training and conventional surgery training in improving their confidence with combat medical skills. The difference in scores was compared using the student t-test. Significance was considered as P Results: The total score was significantly higher for entry-level FST training than that for conventional surgery training (30.76 ± 4.33 vs. 28.95 ± 4.80, P There was no significant difference between the training for surgical skills confidence scores (18.03 ± 8.04 vs. 17.51 ± 8.30, P = 0.098), but for non-technical skills, the score of entry-level FST training was significantly higher than that of conventional surgery training (12.73 ± 5.39 vs. 11.44 ± 5.62, P The distributions of confidence scores were different under various subgroups by demographics. There were no significant differences in scores between the two training in all specific surgical skill sets except “life-saving surgery” (P = 0.011). Scores of all 4 non-technical skill sets were significantly higher for entry-level FST than those for conventional surgery training (P Conclusions: The training should be considered as an essential strategy to improve confidence in combat medical skills, especially life-saving surgery and non-technical skills, for primary combat surgeons.展开更多
Planting at an optimum density and supplying adequate nitrogen(N) to achieve higher yields is a common practice in crop production, especially for maize(Zea mays L.); however, excessive N fertilizer supply in maiz...Planting at an optimum density and supplying adequate nitrogen(N) to achieve higher yields is a common practice in crop production, especially for maize(Zea mays L.); however, excessive N fertilizer supply in maize production results in reduced N use efficiency(NUE) and severe negative impacts on the environment. This research was conducted to determine the effects of increased plant density and reduced N rate on grain yield, total N uptake, NUE, leaf area index(LAI), intercepted photosynthetically active radiation(IPAR), and resource use efficiency in maize. Field experiments were conducted using a popular maize hybrid Zhengdan 958(ZD958) under different combinations of plant densities and N rates to determine an effective approach for maize production with high yield and high resource use efficiency. Increasing plant density was clearly able to promote N absorption and LAI during the entire growth stage, which allowed high total N uptake and interception of radiation to achieve high dry matter accumulation(DMA), grain yield, NUE, and radiation use efficiency(RUE). However, with an increase in plant density, the demand of N increased along with grain yield. Increasing N rate can significantly increase the DMA, grain yield, LAI, IPAR, and RUE. However, this increase was non-linear and due to the input of too much N fertilizers, the efficiency of N use at NCK(320 kg ha^(–1)) was low. An appropriate reduction in N rate can therefore lead to higher NUE despite a slight loss in grain production. Taking into account both the need for high grain yield and resource use efficiency, a 30% reduction in N supply, and an increase in plant density of 3 plants m^(–2), compared to LD(5.25 plants m^(–2)), would lead to an optimal balance between yield and resource use efficiency.展开更多
Using the tomography image, a method to characterize the 3D spatial distributions of increased porosity was proposed, and the increased porosity distributions of cement pastes with different leaching degrees were give...Using the tomography image, a method to characterize the 3D spatial distributions of increased porosity was proposed, and the increased porosity distributions of cement pastes with different leaching degrees were given using the current method. The leaching processes of CH/C-S-H and the contribution of CH/C-S-H leaching to porosity evolution were discussed. The proposed method can be applied to all cement- based materials with any leaching degrees. From the quantitative increased porosity results, we find that the CH leaching finished quickly on the sharp CH leaching front.展开更多
Kidney stones are a common urinary system condition that can progress to kidney disease. Previous studies on the association between tea consumption and kidney stones are inconsistent. A cross-sectional study to inves...Kidney stones are a common urinary system condition that can progress to kidney disease. Previous studies on the association between tea consumption and kidney stones are inconsistent. A cross-sectional study to investigate the association between tea consumption and kidney stones was conducted from 2013 to 2014 and recruited 9,078 northern Chinese adults. A total of 8,807 participants were included in the final analysis. Participants' prevalence of kidney stones was 1.07%, 1.73%, and 2.25% based on their tea consumption frecluencv of never, occasionally,展开更多
The NCEP/NCAR reanalysis, Japan Meteorological Agency(JMA) tropical cyclone tracks and intensive surface observations are used to diagnose the features of moisture transport of tropical storm Bilis(No. 0604), which is...The NCEP/NCAR reanalysis, Japan Meteorological Agency(JMA) tropical cyclone tracks and intensive surface observations are used to diagnose the features of moisture transport of tropical storm Bilis(No. 0604), which is simulated by the WRF(weather research and forecasting) mesoscale numerical model. It is shown that the Bilis was linked with the moisture channel in the lower latitudes after its landing. Meanwhile, the cross-equatorial flows over 80°-100°E and Somali were active and brought abundant water vapor into the tropical storm, facilitating the maintenance of the landing storm with intensified heavy rainfall along its path. The simulation suggested that the decreased water vapor from lower latitudes prevents the maintenance of Bilis and the development of rainfall. While the cross-equatorial flows over 80°-100°E and Somali were in favor of keeping the cyclonic circulation over land. If the moisture supply fro m the Somali jet stream was reduced, the strength and area of heavy rainfall in tropical cyclone would be remarkably weakened. Consequently, the decreased water vapor from lower latitudes can remarkably suppress the deep convection in tropical storm, then Bilis was damped without the persistent energy support and the rainfall was diminished accordingly.展开更多
Local temperature changes in mountain areas are significantly affected by the uplifted mountain terrains. Understanding how temperature increase with mountain terrains is an important component in accurately modeling ...Local temperature changes in mountain areas are significantly affected by the uplifted mountain terrains. Understanding how temperature increase with mountain terrains is an important component in accurately modeling the spatial distribution of temperature. The study, after minimizing the effect of elevation and latitude, quantitatively simulated the temperature increase in the uplifted mountain terrains, described the characteristics in the spatial distribution of warming areas with different magnitudes, and identified the correlated indices of mountain bodies for warming. Selecting Yunnan Province in southwest China as the study area, we simulated the warming field on a baseline surface at the average elevation of 2000 m and average latitude of 24.96°. The results indicated that the warming magnitudes in different local areas varied with the change in the spatial locations, and the warming process concentrated in the mountainous regions. Throughout the entire study area, the warming field presented a general pattern of three terraces from the regions of high mountains to middle mountains and then low mountains. The areasof high warming magnitude mainly surrounded large mountain bodies and were distributed on the upper part. The areas of low warming magnitude clustered in the valleys and basins of the middle mountain region, mostly on the lower part of the large mountain bodies and its branches. The areas with zero warming magnitude occurred in the low mountains and broad valleys, which were distributed largely on the lower parts of the middle mountains and in most of the valleys. Quantified sampling analysis demonstrated good positive correlation between the warming magnitudes in uplifted mountain terrains and the volume index of the mountain body, as well as elevation difference, with the coefficients corresponding to 0.82 and 0.91, respectively.展开更多
In the Northwest Pacific Ocean, the squid jigging fisheries from China, Japan and other countries and regions have targeted the west winter-spring cohort of neon flying squid(Ommastrephes bartramii) from August to N...In the Northwest Pacific Ocean, the squid jigging fisheries from China, Japan and other countries and regions have targeted the west winter-spring cohort of neon flying squid(Ommastrephes bartramii) from August to November since the 1970 s. This squid is a short-lived ecological opportunist with a life-span of about one year,and its population is labile and recruitment variability is driven by the environment or climate change. This variability provides a challenge for ones to forecast the key habitats affected by climate change. The catch data of O. bartramii from Chinese squid jigging fishery and the satellite-derived sea surface temperature(SST) data are used in the Northwest Pacific Ocean from August to November of 1998 to 2004, the SST preferences of O.bartramii corresponding to high values of catch per fishing day(CPUE) are determined and monthly potential habitats are predicted using a histogram analysis of the SST data. The possible changes in the potential habitats of O. bartramii in the Northwest Pacific Ocean are estimated under four climate change scenarios based on the Fourth Assessment Report(AR4) of the Intergovernmental Panel on Climate Change, i.e., 0.5, 1, 2 and 4°C increases in the SST because of the climate change. The results reveal an obvious poleward shift of the potential habitats of O. bartramii in the Northwest Pacific Ocean.展开更多
Well-preserved specimens of Kepingophyllum aksuence Wu et Chow were collected from Early Permian strata in western Tarim Basin, Xinjiang. More than 100 serial thin sections were made for this study. Kepingophyllum aks...Well-preserved specimens of Kepingophyllum aksuence Wu et Chow were collected from Early Permian strata in western Tarim Basin, Xinjiang. More than 100 serial thin sections were made for this study. Kepingophyllum aksuence displays a unique increase pattern. The bud appears in lonsdaleoid dissepiments between the corallites where the wall of parent corallite disappears and the area becomes aphroid. This increase pattern is different from other lateral increases of most colonial rngose corals, and therefore has taxonomic significance to differentiate Kepingophyllidae from other compound rugose corals. It is also discussed that Kepingophyllum aksuence has a high "reproductive integration", which means a rapid growth of buds during the offsetting process. Kepingophyllum was possibly originated from Ivanovia and was also a probable ancestor of Wentzellophyllum, which is supported here by more or less the similarity of the blastogeny in different stages of three taxa.展开更多
A method of estimating the critical rate of temperature increase of thermal explosion for the first orderautocatalytic decomposition reaction system using non-isothermal DSC is presented. Information is obtained on th...A method of estimating the critical rate of temperature increase of thermal explosion for the first orderautocatalytic decomposition reaction system using non-isothermal DSC is presented. Information is obtained on theincreasing rate of temperature in nitrocellulose containing 13.54% of nitrogen when the first order autocatalytic decomposition converts into thermal explosion.展开更多
Using smashing ridging tillage machine and smashing ridging technology invented by the authors, transformation test of saline-alkali land by smashing ridging was conducted respectively in Xinjiang and Shaanxi during 2...Using smashing ridging tillage machine and smashing ridging technology invented by the authors, transformation test of saline-alkali land by smashing ridging was conducted respectively in Xinjiang and Shaanxi during 2015 -2016. The results showed, in severe saline-alkali soil of Xin-jiang ,after growing cotton by smashing ridging, total salt in soil decreased by 31.31 %, cotton production increased by 48.80%, and salinity level declined from severe to moderate; in mild saline-alkali soil of Shaanxi, after growing summer corn by smashing ridging, total salt in soil decreased by 42.37%, corn yield increased by 34.83%, salinity degree changed from mild desalination to normal farmland ; in Ningxia, Inner Mongolia 7 Gansu ,Jilin, Henan, Hebei, and so on, smashing ridging tillage practice in different types of saline-alkali land was conducted ; according to the salt reduction and yield increase effects of saline-alkali land after smashing ridging, the development prospect of smashing ridging technique in improvement and application of saline-alkali land was proposed.展开更多
The disposable income per capita of rural residents in Tibet was 7471 yuan in 2014. There is a high gap with the national average disposable income per capita of rural residents( 10489 yuan). Thus,it is urgent to incr...The disposable income per capita of rural residents in Tibet was 7471 yuan in 2014. There is a high gap with the national average disposable income per capita of rural residents( 10489 yuan). Thus,it is urgent to increase income of farmers and herdsmen in Tibet. On the basis of literature in recent years,this paper analyzed methods for increasing income of farmers and herdsmen in Tibet,major factors restricting increase of their income,and approaches for increasing their income. It is expected to provide certain reference for further expanding ideas of increase of their income in the new period.展开更多
:AIM To construct Hsp90 antisense RNAeukaryotic expression vector, transfect it intoSGC7901 and SGC7901/VCR of MDR-type humangastric cancer cell lines, HCC7402 of humanhepatic cancer and Eel09 of human esophagealcance...:AIM To construct Hsp90 antisense RNAeukaryotic expression vector, transfect it intoSGC7901 and SGC7901/VCR of MDR-type humangastric cancer cell lines, HCC7402 of humanhepatic cancer and Eel09 of human esophagealcancer cell lines, and to study the cell cycledistribution of the gene transected cells andtheir response to chemotherapeutic drugs.METHODS A I .03kb cDNA sequence of Hsp90Pwas obtained from the primary plasmid phHsp90by EcoR 1 and BamH I nuclease digestion andwas cloned to the EcoR 1 and BamH 1 site ofthe pcDNA by T4DNA ligase and an antisenseorientation of Hsp900 expression vector wasconstructed. The constructs were transfectedwith lipofectamine and positive clones wereselected with G418. The expression of RNA wasdetermined with dot blotting and RNaseprotection assay, and the expression of Hsp90protein determined with Western blot. Cell cycledistribution of the transfectants was analyzedwith flow cytometry, and the drug sensitivity ofthe transfectants to adriamycin (ADR ),vincrinstine (VCR ), mitomycin (MMC ) andcyclophosphamide (CTX ) with MTT andintracellular drug concentration of thetransfectants was determined with flowcytometry.RESULTS In EcoR 1 and BamH I restrictionanalysis, the size and the direction of the clonedsequence of Hsp900 remained what had beendesigned and the gene constructs were namedpcDNA-Hsp90. AH^SGC7901, AH^SGC7901/ VCR,AH-HCC7402 and AH-Eel09 cell clones allexpressed Hsp90 anti--sense RNA. Theexpression of Hsp90 was down--regulated in AHSGC7901, AH--SGC7901/ VCR, AH-HCC7402 andAH--Eel09 cell clones. Cell cycle distribution waschanged differently. In AH-SGC7901/ VCR andAH-Ec109 cells, G, phase cells were increased; Sphase and G, phase cells were decreased ascompared with their parental cell lines. In AHSGC7901 cell, G, phase cells were decreased, Qphase cells increased and S phase cells were notchanged, and in AH-HCC7402 cells G,, S and qphase cells remained unchanged as comparedwith their parental cell lines. The sensitivity ofAH--SGC7901, AH--SGC7901/ VCR, AH-HCC7402 andAH-Ec109 to chemotherapeutic drugs, thesensitivity ot AH--SGC7901/ VCR to ADR, VCR,MMC and CTX the sensitivity of AH-HCC7402 toADR and VCR, and the sensitivity of Eel09 toADR, VCR and CTX all increased as comparedwith their parental cell lines. The meanfluorescence intensity of ADR in AH--SGC7901,AH-SGC7901/ VCR, AH--HCC7402 and AH-Ec109was also significantly elevated (P< 0. 05).CONCLUSION Down-regulation of HsP90 couldchange cell cycle distribution and increase thedrug sensitivity of tumor cells.展开更多
Striated muscle tissue contains fibers with high oxidative capacity (heart muscle), higher oxidative capacity (type I and IIA fibers of skeletal muscle) and low oxidative capacity (type IIB/X fibers of skeletal muscle...Striated muscle tissue contains fibers with high oxidative capacity (heart muscle), higher oxidative capacity (type I and IIA fibers of skeletal muscle) and low oxidative capacity (type IIB/X fibers of skeletal muscle). Muscle fibers with higher oxidative capacity contain large mitochondria tightly packed with cristae as well as small forms of mitochondria containing relatively few cristae. The intensive development of the mitochondrial apparatus in the post-activity period reflects the adaptive processes, which is intended to supply the increased energy requirements of muscle fibers with higher oxidative capacity. Muscle fibers with low oxidative capacity contain significantly less mitochondria than fibers with higher capacity. It is typical to type IIB fibers that after intensive muscle activity there are damaged myofibrils in a relatively small area, some myofibrils are twisted and lose the connection with the neighboring structures. It is still not fully known how skeletal muscles with different oxidative capacity respond to an increased functional activity and what differences exist in these fibers between oxidative capacity and function of myofibrils. The aim of the present short review was to compare structural-functional changes in mitochondrial and myofibrillar compartments of heart and skeletal muscle fibers with different oxidative capacity and the effect of increased functional activity on the interaction of these compartments.展开更多
A capacity increase is often observed in the early stage of Li-ion battery cycling.This study explores the phenomena involved in the capacity increase from the full cell,electrodes,and materials perspective through a ...A capacity increase is often observed in the early stage of Li-ion battery cycling.This study explores the phenomena involved in the capacity increase from the full cell,electrodes,and materials perspective through a combination of non-destructive diagnostic methods in a full cell and post-mortem analysis in a coin cell.The results show an increase of 1%initial capacity for the battery aged at 100%depth of discharge(DOD)and 45℃.Furthermore,large DODs or high temperatures accelerate the capacity increase.From the incremental capacity and differential voltage(IC-DV)analysis,we concluded that the increased capacity in a full cell originates from the graphite anode.Furthermore,graphite/Li coin cells show an increased capacity for larger DODs and a decreased capacity for lower DODs,thus in agreement with the full cell results.Post-mortem analysis results show that a larger DOD enlarges the graphite dspace and separates the graphite layer structure,facilitating the Li+diffusion,hence increasing the battery capacity.展开更多
Throughout its more than 5000-year history,China has a long tradition of encouraging active engagement in physical and sport activities.1,2This enduring tradition,however,has been facing some major headwinds as China ...Throughout its more than 5000-year history,China has a long tradition of encouraging active engagement in physical and sport activities.1,2This enduring tradition,however,has been facing some major headwinds as China continues to experience demographic and environmental changes related to aging,urbanization,and lifestyle shifts.3-5Mounting evidence indicates increasing levels of sedentary behaviors。展开更多
Dear Editor,Galectin-1, one of galactoside-binding lectin family proteins, has been shown to regulate cell growth, migration, and proliferation, where it binds many receptors depending on their glycosylation profile, ...Dear Editor,Galectin-1, one of galactoside-binding lectin family proteins, has been shown to regulate cell growth, migration, and proliferation, where it binds many receptors depending on their glycosylation profile, rather than its specific receptors.展开更多
Urinary brain-derived neurotrophic factor(BDNF), an ubiquitous neurotrophin, was found to rise in patients with benign prostatic hyperplasia(BPH). We hypothesized that the urinary level of BDNF could be a potentia...Urinary brain-derived neurotrophic factor(BDNF), an ubiquitous neurotrophin, was found to rise in patients with benign prostatic hyperplasia(BPH). We hypothesized that the urinary level of BDNF could be a potential biomarker for lower urinary tract symptoms(LUTS) in patients with BPH. Totally, 76 patients with BPH-caused LUTS and 32 male control subjects without BPH were enrolled. International Prostate Symptom Score(IPSS) was applied to assess the symptom severity of LUTS. Urodynamic tests were performed for the diagnosis of underlying detrusor overactivity(DO) in the patients with BPH. Urine samples were collected from all subjects. Urinary BDNF levels were measured using enzyme-linked immunosorbent assays and normalized by urinary creatinine(Cr) levels. Seventy-six BPH patients were divided into moderate LUTS group(n=51, 720) according to the IPSS. Of the 76 BPH patients, DO was present in 34(44.7%) according to the urodynamic test. The urinary BDNF/Cr levels were significantly higher in BPH patients with moderate LUTS(8.29±3.635, P〈0.0001) and severe LUTS(11.8±6.44, P〈0.0001) than normal controls(1.71±0.555). Patients with severe LUTS tended to have higher urinary BDNF/Cr levels than patients with moderate LUTS(11.8±6.44 vs. 8.29±3.635, P=0.000). The conditions of BPH with LUTS correlated with elevated urinary BDNF levels, and urinary BDNF levels were even higher in BPH-DO patients. The results of this study have provided evidence to suggest that urinary BDNF level test could evaluate the severity of LUTS in BPH patients, and BDNF level can be used as a biomarker展开更多
基金supported by the National Natural Science Foundation of China (Grant No. 42061004)the Joint Special Project of Agricultural Basic Research of Yunnan Province (Grant No. 202101BD070001093)the Youth Special Project of Xingdian Talent Support Program of Yunnan Province
文摘Abrupt near-surface temperature changes in mountainous areas are a special component of the mountain climate system.Fast and accurate measurements of the locations,intensity,and width of the near-surface changes are necessary but highly difficult due to the complicated environmental conditions and instrumental issues.This paper develops a spatial pattern recognition method to measure the near-surface high temperature increase(NSHTI),one of the lesser-attended changes.First,raster window measurement was proposed to calculate the temperature lapse rate using MODIS land surface temperature and SRTM DEM data.It fully considers the terrain heights of two neighboring cells on opposite or adjacent slopes with a moving window of 3×3 cell size.Second,a threshold selection was performed to identify the NSHTI cells using a threshold of-0.65℃/100 m.Then,the NSHTI strips were parameterized through raster vectorization and spatial analysis.Taking Yunnan,a mountainous province in southwestern China,as the study area,the results indicate that the NSHTI cells concentrate in a strip-like pattern along the mountains and valleys,and the strips are almost parallel to the altitude contours with a slight northward uplift.Also,they are located mostly at a 3/5 height of high mountains or within 400 m from the valley floors,where the controlling topographic index is the altitude of the terrain trend surface but not the absolute elevation and the topographic uplift height and cutting depth.Additionally,the NSHTI intensity varies with the geographic locations and the proportions increase with an exponential trend,and the horizontal width has a mean of about 1000 m and a maximum of over 5000 m.The result demonstrates that the proposed method can effectively recognize NSHTI boundaries over mountains,providing support for the modeling of weather and climate systems and the development of mountain resources.
文摘Several notable issues arise from overcrowding in an emergency department (ED) for both patients and staff. Longer wait times, higher ambulance diversion rates, longer stays, higher incidence of medical errors, higher rates of patient mortality, and greater harm to hospitals due to financial losses are some of these problems. Collaboration is crucial in the healthcare industry since it determines the team’s hourly performance in managing patient care. By using Walker and Avant’s (2011) concept analysis method, the author reviewed the literature to better understand ED crowding, to ensure that patients receive safe treatment in a timely manner, and to highlight best practices that can be identified through concept analysis and practice evaluations. In conducting this concept analysis, Walker and Avant’s framework was applied to examine the nature of the findings selected for the advancement of the concept. Everyone working in the ED, from those who determine policy to those on the front lines continually encounter new obstacles, but has little or no time to formulate fresh concepts or reconsider how ED treatment is provided. Overcrowding occurs when the number of patients requiring attention, awaiting transfer, or undergoing diagnosis and treatment exceeds the physical capacity of ED staff. If a clear plan is not in place to increase and improve services in proportion to a growing population, this situation will persist.
文摘Background: In recent years, we have established an entry-level Forward Surgical Team (FST) training program in a Chinese military medical university for the 5th grade undergraduates, who would be deployed to different military medical services as primary combat surgeons. This study aimed to assess the role of this pre-service training in improving their confidence with combat medical skills, after several years since they received the training. Methods: We conducted a nationwide survey of 239 primary combat surgeons who have ever participated in an entry-level FST training program before deployment between June 2016 and June 2020, which was for evaluating on a 5-point Likert scale the benefits of entry-level FST training and conventional surgery training in improving their confidence with combat medical skills. The difference in scores was compared using the student t-test. Significance was considered as P Results: The total score was significantly higher for entry-level FST training than that for conventional surgery training (30.76 ± 4.33 vs. 28.95 ± 4.80, P There was no significant difference between the training for surgical skills confidence scores (18.03 ± 8.04 vs. 17.51 ± 8.30, P = 0.098), but for non-technical skills, the score of entry-level FST training was significantly higher than that of conventional surgery training (12.73 ± 5.39 vs. 11.44 ± 5.62, P The distributions of confidence scores were different under various subgroups by demographics. There were no significant differences in scores between the two training in all specific surgical skill sets except “life-saving surgery” (P = 0.011). Scores of all 4 non-technical skill sets were significantly higher for entry-level FST than those for conventional surgery training (P Conclusions: The training should be considered as an essential strategy to improve confidence in combat medical skills, especially life-saving surgery and non-technical skills, for primary combat surgeons.
基金the National Natural Science Foundation of China(3117 1497)the National Basic Research Program of China(973 Program,2011CB100105)+1 种基金the National Food Science and Technology of High Yield Program of China(2011BAD16B09)the Special Fund for Agro-scientific Research in the Public Interest of China(201203096)
文摘Planting at an optimum density and supplying adequate nitrogen(N) to achieve higher yields is a common practice in crop production, especially for maize(Zea mays L.); however, excessive N fertilizer supply in maize production results in reduced N use efficiency(NUE) and severe negative impacts on the environment. This research was conducted to determine the effects of increased plant density and reduced N rate on grain yield, total N uptake, NUE, leaf area index(LAI), intercepted photosynthetically active radiation(IPAR), and resource use efficiency in maize. Field experiments were conducted using a popular maize hybrid Zhengdan 958(ZD958) under different combinations of plant densities and N rates to determine an effective approach for maize production with high yield and high resource use efficiency. Increasing plant density was clearly able to promote N absorption and LAI during the entire growth stage, which allowed high total N uptake and interception of radiation to achieve high dry matter accumulation(DMA), grain yield, NUE, and radiation use efficiency(RUE). However, with an increase in plant density, the demand of N increased along with grain yield. Increasing N rate can significantly increase the DMA, grain yield, LAI, IPAR, and RUE. However, this increase was non-linear and due to the input of too much N fertilizers, the efficiency of N use at NCK(320 kg ha^(–1)) was low. An appropriate reduction in N rate can therefore lead to higher NUE despite a slight loss in grain production. Taking into account both the need for high grain yield and resource use efficiency, a 30% reduction in N supply, and an increase in plant density of 3 plants m^(–2), compared to LD(5.25 plants m^(–2)), would lead to an optimal balance between yield and resource use efficiency.
基金Funded by the National Basic Research Program of China(No.2009CB623203)the National Natural Science Foundation of China(No.51008072)
文摘Using the tomography image, a method to characterize the 3D spatial distributions of increased porosity was proposed, and the increased porosity distributions of cement pastes with different leaching degrees were given using the current method. The leaching processes of CH/C-S-H and the contribution of CH/C-S-H leaching to porosity evolution were discussed. The proposed method can be applied to all cement- based materials with any leaching degrees. From the quantitative increased porosity results, we find that the CH leaching finished quickly on the sharp CH leaching front.
基金supported by the Medical Science and Technology Project of Zhejiang Province[2014KYA231]
文摘Kidney stones are a common urinary system condition that can progress to kidney disease. Previous studies on the association between tea consumption and kidney stones are inconsistent. A cross-sectional study to investigate the association between tea consumption and kidney stones was conducted from 2013 to 2014 and recruited 9,078 northern Chinese adults. A total of 8,807 participants were included in the final analysis. Participants' prevalence of kidney stones was 1.07%, 1.73%, and 2.25% based on their tea consumption frecluencv of never, occasionally,
基金Major Program of the Natural Science Researches for Colleges and Universities in Jiangsu Province(14KJA170004)'333'Project of Jiangsu ProvinceNational Natural Science Foundation of China(41575081,41175061)
文摘The NCEP/NCAR reanalysis, Japan Meteorological Agency(JMA) tropical cyclone tracks and intensive surface observations are used to diagnose the features of moisture transport of tropical storm Bilis(No. 0604), which is simulated by the WRF(weather research and forecasting) mesoscale numerical model. It is shown that the Bilis was linked with the moisture channel in the lower latitudes after its landing. Meanwhile, the cross-equatorial flows over 80°-100°E and Somali were active and brought abundant water vapor into the tropical storm, facilitating the maintenance of the landing storm with intensified heavy rainfall along its path. The simulation suggested that the decreased water vapor from lower latitudes prevents the maintenance of Bilis and the development of rainfall. While the cross-equatorial flows over 80°-100°E and Somali were in favor of keeping the cyclonic circulation over land. If the moisture supply fro m the Somali jet stream was reduced, the strength and area of heavy rainfall in tropical cyclone would be remarkably weakened. Consequently, the decreased water vapor from lower latitudes can remarkably suppress the deep convection in tropical storm, then Bilis was damped without the persistent energy support and the rainfall was diminished accordingly.
基金supported by the National Natural Science Foundation of China (Grant No. 41561004)the Forestry Industry Research Special Funds for Public Welfare Projects of China (Grant No. 21404402-2)the Scientific and Technological Innovation Talent Project of Yunnan Province (Grant No. 2014HC014)
文摘Local temperature changes in mountain areas are significantly affected by the uplifted mountain terrains. Understanding how temperature increase with mountain terrains is an important component in accurately modeling the spatial distribution of temperature. The study, after minimizing the effect of elevation and latitude, quantitatively simulated the temperature increase in the uplifted mountain terrains, described the characteristics in the spatial distribution of warming areas with different magnitudes, and identified the correlated indices of mountain bodies for warming. Selecting Yunnan Province in southwest China as the study area, we simulated the warming field on a baseline surface at the average elevation of 2000 m and average latitude of 24.96°. The results indicated that the warming magnitudes in different local areas varied with the change in the spatial locations, and the warming process concentrated in the mountainous regions. Throughout the entire study area, the warming field presented a general pattern of three terraces from the regions of high mountains to middle mountains and then low mountains. The areasof high warming magnitude mainly surrounded large mountain bodies and were distributed on the upper part. The areas of low warming magnitude clustered in the valleys and basins of the middle mountain region, mostly on the lower part of the large mountain bodies and its branches. The areas with zero warming magnitude occurred in the low mountains and broad valleys, which were distributed largely on the lower parts of the middle mountains and in most of the valleys. Quantified sampling analysis demonstrated good positive correlation between the warming magnitudes in uplifted mountain terrains and the volume index of the mountain body, as well as elevation difference, with the coefficients corresponding to 0.82 and 0.91, respectively.
基金The National Key Technologies Research and Development Program of China under contract No.2013BAD13B00the Public Science and Technology Research Funds Project of Ocean under contract No.20155014the Shanghai Universities First-class Disciplines Project(Fisheries)
文摘In the Northwest Pacific Ocean, the squid jigging fisheries from China, Japan and other countries and regions have targeted the west winter-spring cohort of neon flying squid(Ommastrephes bartramii) from August to November since the 1970 s. This squid is a short-lived ecological opportunist with a life-span of about one year,and its population is labile and recruitment variability is driven by the environment or climate change. This variability provides a challenge for ones to forecast the key habitats affected by climate change. The catch data of O. bartramii from Chinese squid jigging fishery and the satellite-derived sea surface temperature(SST) data are used in the Northwest Pacific Ocean from August to November of 1998 to 2004, the SST preferences of O.bartramii corresponding to high values of catch per fishing day(CPUE) are determined and monthly potential habitats are predicted using a histogram analysis of the SST data. The possible changes in the potential habitats of O. bartramii in the Northwest Pacific Ocean are estimated under four climate change scenarios based on the Fourth Assessment Report(AR4) of the Intergovernmental Panel on Climate Change, i.e., 0.5, 1, 2 and 4°C increases in the SST because of the climate change. The results reveal an obvious poleward shift of the potential habitats of O. bartramii in the Northwest Pacific Ocean.
基金supported by the Chinese Academy of Sciences (KZCX2-YW-122, KZCX2-YW-Q050603)the Ministry of Science and Technology of China (2006FY120300-8)+1 种基金National Natural Science Foundation of China (NSFC)the CAS/SAFEA International Partnership Program for Creative Research Teams
文摘Well-preserved specimens of Kepingophyllum aksuence Wu et Chow were collected from Early Permian strata in western Tarim Basin, Xinjiang. More than 100 serial thin sections were made for this study. Kepingophyllum aksuence displays a unique increase pattern. The bud appears in lonsdaleoid dissepiments between the corallites where the wall of parent corallite disappears and the area becomes aphroid. This increase pattern is different from other lateral increases of most colonial rngose corals, and therefore has taxonomic significance to differentiate Kepingophyllidae from other compound rugose corals. It is also discussed that Kepingophyllum aksuence has a high "reproductive integration", which means a rapid growth of buds during the offsetting process. Kepingophyllum was possibly originated from Ivanovia and was also a probable ancestor of Wentzellophyllum, which is supported here by more or less the similarity of the blastogeny in different stages of three taxa.
文摘A method of estimating the critical rate of temperature increase of thermal explosion for the first orderautocatalytic decomposition reaction system using non-isothermal DSC is presented. Information is obtained on theincreasing rate of temperature in nitrocellulose containing 13.54% of nitrogen when the first order autocatalytic decomposition converts into thermal explosion.
基金Supported by National Science and Technology Support Program(2014BAD06B05)
文摘Using smashing ridging tillage machine and smashing ridging technology invented by the authors, transformation test of saline-alkali land by smashing ridging was conducted respectively in Xinjiang and Shaanxi during 2015 -2016. The results showed, in severe saline-alkali soil of Xin-jiang ,after growing cotton by smashing ridging, total salt in soil decreased by 31.31 %, cotton production increased by 48.80%, and salinity level declined from severe to moderate; in mild saline-alkali soil of Shaanxi, after growing summer corn by smashing ridging, total salt in soil decreased by 42.37%, corn yield increased by 34.83%, salinity degree changed from mild desalination to normal farmland ; in Ningxia, Inner Mongolia 7 Gansu ,Jilin, Henan, Hebei, and so on, smashing ridging tillage practice in different types of saline-alkali land was conducted ; according to the salt reduction and yield increase effects of saline-alkali land after smashing ridging, the development prospect of smashing ridging technique in improvement and application of saline-alkali land was proposed.
基金Supported by Tibet Project of Humanities and Social Science Foundation of Ministry of Education(12XZJC790002)Young Scholar Project of Humanities and Social Science Foundation of Ministry of Education(13YJCZH156)Special Project of Philosophy and Social Science of Tibet Autonomous Region(13BJY012)
文摘The disposable income per capita of rural residents in Tibet was 7471 yuan in 2014. There is a high gap with the national average disposable income per capita of rural residents( 10489 yuan). Thus,it is urgent to increase income of farmers and herdsmen in Tibet. On the basis of literature in recent years,this paper analyzed methods for increasing income of farmers and herdsmen in Tibet,major factors restricting increase of their income,and approaches for increasing their income. It is expected to provide certain reference for further expanding ideas of increase of their income in the new period.
基金Project supported by the National Natural Science Foundation of China,No.39570806National Excel1ent Youth Scientific Foundation,No.3952020.
文摘:AIM To construct Hsp90 antisense RNAeukaryotic expression vector, transfect it intoSGC7901 and SGC7901/VCR of MDR-type humangastric cancer cell lines, HCC7402 of humanhepatic cancer and Eel09 of human esophagealcancer cell lines, and to study the cell cycledistribution of the gene transected cells andtheir response to chemotherapeutic drugs.METHODS A I .03kb cDNA sequence of Hsp90Pwas obtained from the primary plasmid phHsp90by EcoR 1 and BamH I nuclease digestion andwas cloned to the EcoR 1 and BamH 1 site ofthe pcDNA by T4DNA ligase and an antisenseorientation of Hsp900 expression vector wasconstructed. The constructs were transfectedwith lipofectamine and positive clones wereselected with G418. The expression of RNA wasdetermined with dot blotting and RNaseprotection assay, and the expression of Hsp90protein determined with Western blot. Cell cycledistribution of the transfectants was analyzedwith flow cytometry, and the drug sensitivity ofthe transfectants to adriamycin (ADR ),vincrinstine (VCR ), mitomycin (MMC ) andcyclophosphamide (CTX ) with MTT andintracellular drug concentration of thetransfectants was determined with flowcytometry.RESULTS In EcoR 1 and BamH I restrictionanalysis, the size and the direction of the clonedsequence of Hsp900 remained what had beendesigned and the gene constructs were namedpcDNA-Hsp90. AH^SGC7901, AH^SGC7901/ VCR,AH-HCC7402 and AH-Eel09 cell clones allexpressed Hsp90 anti--sense RNA. Theexpression of Hsp90 was down--regulated in AHSGC7901, AH--SGC7901/ VCR, AH-HCC7402 andAH--Eel09 cell clones. Cell cycle distribution waschanged differently. In AH-SGC7901/ VCR andAH-Ec109 cells, G, phase cells were increased; Sphase and G, phase cells were decreased ascompared with their parental cell lines. In AHSGC7901 cell, G, phase cells were decreased, Qphase cells increased and S phase cells were notchanged, and in AH-HCC7402 cells G,, S and qphase cells remained unchanged as comparedwith their parental cell lines. The sensitivity ofAH--SGC7901, AH--SGC7901/ VCR, AH-HCC7402 andAH-Ec109 to chemotherapeutic drugs, thesensitivity ot AH--SGC7901/ VCR to ADR, VCR,MMC and CTX the sensitivity of AH-HCC7402 toADR and VCR, and the sensitivity of Eel09 toADR, VCR and CTX all increased as comparedwith their parental cell lines. The meanfluorescence intensity of ADR in AH--SGC7901,AH-SGC7901/ VCR, AH--HCC7402 and AH-Ec109was also significantly elevated (P< 0. 05).CONCLUSION Down-regulation of HsP90 couldchange cell cycle distribution and increase thedrug sensitivity of tumor cells.
文摘Striated muscle tissue contains fibers with high oxidative capacity (heart muscle), higher oxidative capacity (type I and IIA fibers of skeletal muscle) and low oxidative capacity (type IIB/X fibers of skeletal muscle). Muscle fibers with higher oxidative capacity contain large mitochondria tightly packed with cristae as well as small forms of mitochondria containing relatively few cristae. The intensive development of the mitochondrial apparatus in the post-activity period reflects the adaptive processes, which is intended to supply the increased energy requirements of muscle fibers with higher oxidative capacity. Muscle fibers with low oxidative capacity contain significantly less mitochondria than fibers with higher capacity. It is typical to type IIB fibers that after intensive muscle activity there are damaged myofibrils in a relatively small area, some myofibrils are twisted and lose the connection with the neighboring structures. It is still not fully known how skeletal muscles with different oxidative capacity respond to an increased functional activity and what differences exist in these fibers between oxidative capacity and function of myofibrils. The aim of the present short review was to compare structural-functional changes in mitochondrial and myofibrillar compartments of heart and skeletal muscle fibers with different oxidative capacity and the effect of increased functional activity on the interaction of these compartments.
基金supported by a grant from the China Scholarship Council(202006370035 and 202006220024)supported by the National Natural Science Foundation of China(52107229)。
文摘A capacity increase is often observed in the early stage of Li-ion battery cycling.This study explores the phenomena involved in the capacity increase from the full cell,electrodes,and materials perspective through a combination of non-destructive diagnostic methods in a full cell and post-mortem analysis in a coin cell.The results show an increase of 1%initial capacity for the battery aged at 100%depth of discharge(DOD)and 45℃.Furthermore,large DODs or high temperatures accelerate the capacity increase.From the incremental capacity and differential voltage(IC-DV)analysis,we concluded that the increased capacity in a full cell originates from the graphite anode.Furthermore,graphite/Li coin cells show an increased capacity for larger DODs and a decreased capacity for lower DODs,thus in agreement with the full cell results.Post-mortem analysis results show that a larger DOD enlarges the graphite dspace and separates the graphite layer structure,facilitating the Li+diffusion,hence increasing the battery capacity.
文摘Throughout its more than 5000-year history,China has a long tradition of encouraging active engagement in physical and sport activities.1,2This enduring tradition,however,has been facing some major headwinds as China continues to experience demographic and environmental changes related to aging,urbanization,and lifestyle shifts.3-5Mounting evidence indicates increasing levels of sedentary behaviors。
基金Supported by Bayer Yakuhin Ltd,the Uehara Memorial Foundation,the Eye Research Foundation for the Aged,and the Japan National Society for the Prevention of Blindness
文摘Dear Editor,Galectin-1, one of galactoside-binding lectin family proteins, has been shown to regulate cell growth, migration, and proliferation, where it binds many receptors depending on their glycosylation profile, rather than its specific receptors.
基金supported by the Science and Technology Department of Jiangxi Province(No.20141BBG70036)
文摘Urinary brain-derived neurotrophic factor(BDNF), an ubiquitous neurotrophin, was found to rise in patients with benign prostatic hyperplasia(BPH). We hypothesized that the urinary level of BDNF could be a potential biomarker for lower urinary tract symptoms(LUTS) in patients with BPH. Totally, 76 patients with BPH-caused LUTS and 32 male control subjects without BPH were enrolled. International Prostate Symptom Score(IPSS) was applied to assess the symptom severity of LUTS. Urodynamic tests were performed for the diagnosis of underlying detrusor overactivity(DO) in the patients with BPH. Urine samples were collected from all subjects. Urinary BDNF levels were measured using enzyme-linked immunosorbent assays and normalized by urinary creatinine(Cr) levels. Seventy-six BPH patients were divided into moderate LUTS group(n=51, 720) according to the IPSS. Of the 76 BPH patients, DO was present in 34(44.7%) according to the urodynamic test. The urinary BDNF/Cr levels were significantly higher in BPH patients with moderate LUTS(8.29±3.635, P〈0.0001) and severe LUTS(11.8±6.44, P〈0.0001) than normal controls(1.71±0.555). Patients with severe LUTS tended to have higher urinary BDNF/Cr levels than patients with moderate LUTS(11.8±6.44 vs. 8.29±3.635, P=0.000). The conditions of BPH with LUTS correlated with elevated urinary BDNF levels, and urinary BDNF levels were even higher in BPH-DO patients. The results of this study have provided evidence to suggest that urinary BDNF level test could evaluate the severity of LUTS in BPH patients, and BDNF level can be used as a biomarker