Analysis of the causes of primary revision after unicompartmental knee arthroplasty: A case series

BACKGROUND Unicompartmental knee arthroplasty(UKA)has great advantages in the treatment of unicompartmental knee osteoarthritis,but its revision rate is higher than that of total knee arthroplasty.AIM To summarize and analyse the causes of revision after UKA.METHODS This is a retrospective case series study in which the reasons for the first revision after UKA are summarized.We analysed the clinical symptoms,medical histories,laboratory test results,imaging examination results and treatment processes of the patients who underwent revision and summarized the reasons for primary revision after UKA.RESULTS A total of 13 patients,including 3 males and 10 females,underwent revision surgery after UKA.The average age of the included patients was 67.62 years.The prosthesis was used for 3 d to 72 months.The main reasons for revision after UKA were improper suturing of the surgical opening(1 patient),osteophytes(2 patients),intra-articular loose bodies(2 patients),tibial prosthesis loosening(2 patients),rheumatoid arthritis(1 patient),gasket dislocation(3 patients),anterior cruciate ligament injury(1 patient),and medial collateral ligament injury with residual bone cement(1 patient).CONCLUSION The causes of primary revision after UKA were gasket dislocation,osteophytes,intra-articular loose bodies and tibial prosthesis loosening.Avoidance of these factors may greatly reduce the rate of revision after UKA,improve patient satisfaction and reduce medical burden.

A Research on the Early Effect of Unicompartmental Knee Arthroplasty for Unicompartment Osteoarthritis of the Knee

Objective: To evaluate the early clinical effect of unicompartmental knee arthroplasty (UKA) for medial unicompartment osteoarthritis of knee in the old people, providing the evidence for the treatment of clinic. Methods: From January of 2016 to January of 2017, 20 cases of knee osteoarthritis in medial unicompartment were treated by unicompartmental knee arthroplasty. The knee joint range of motion (ROM), visual analogue scale (VAS) and knee functional Hospital for Special Surgery (HSS) scores were preoperatively recorded. The loss of blood and time of operation were intraoperative recorded. The satisfaction of patient, knee joint range of motion (ROM) and knee functional special surgical hospital score (HSS score) were postoperatively recorded at one year. Results: All patients have been followed up at an average of twelve months. The operation time was 94 - 135 min, mean 105.6 min. The blood loss was 150 - 500 ml, mean 315 ml. The postoperative HSS and ROM were both reduced. The last follow-up, there were no meniscus subluxation, loose prosthesis, and lateral ventricular osteoarthritis or other complications. Conclusion: Unicompartmental knee arthroplasty has the advantages of small operation trauma, early postoperative effect and quick recovery.

Outcomes of mobile bearing unicompartmental knee arthroplasty in medial osteoarthritis knee with and without preoperative genu recurvatum

AIM To compare clinical outcomes of patients with and without preoperative genu recurvatum(GR) following mobile bearing unicompartmental knee arthroplasty(UKA). METHODS We prospectively followed 176 patients for at least 24 mo who had been treated by unilateral, minimally invasive, Oxford UKA. Patients with medial osteoarthritis(OA) knee and preoperative GR(Group Ⅰ) accounted for 18%(n = 32) and patients without preoperative GR(Group Ⅱ) accounted for the remaining 82%(n = 144). Knee score, pain scores, and functional scores were assessed for each patient and compared between the two groups. The incidence of postoperative GRand the postoperative hyperextension angles also were recorded and analyzed. RESULTS The pain score, knee score and functional score were not significantly different between the two groups. Similarly, the incidence of postoperative GR and the measured hyperextension angles were not significantly different between the two groups. The incidence of postoperative GR was 1/32(3.12%) in Group Ⅰ and 1/144(0.69%) in Group Ⅱ(P = 0.34). The mean postoperative hyperextension angles were 2.40°± 2.19°(range: 1°-7°) for Group Ⅰ and 1.57°± 3.51°(range: 1°-6°) for Group Ⅱ(P = 0.65).CONCLUSION Medial OA of the knee and concomitant GR is not a contraindication for the mobile bearing UKA.

Unicompartmental knee prosthetization: Which key-points to consider?

Unicompartmental knee arthroplasty(UKA) has evolved into a suitable option for diseased knees that cannot be managed with arthroscopic treatment and at the same time are not good candidates for total knee replacement. Since meticulous execution of the surgical technique is essential to optimizing UKA outcome, some procedural key-points are mandatory. Templates(phantoms) are then used to size the required prosthetic component(using these radiographs. Arthritic varus(or valgus) knees with an asymptomatic patellofemoral joint are typically ideal for UKA. Metal-backed tibial components should be favourite instead of allpolyethylene tibial components to avoid polyethylene creep that may occur in fixed bearings. Moreover, a proper thickness of the polyethylene layer is mandatory, in order to avoid early failure.

Lateral unicompartmental knee arthroplasty:A review

Isolated lateral compartment osteoarthritis of the knee is a rare condition affecting approximately 1%of the population,which is ten times less common than osteoarthritis affecting only the medial compartment.Unicompartmental knee arthroplasty(UKA)has many potential advantages over total knee arthroplasty.The benefits of UKA include a smaller incision,preservation of more native tissue(including cruciate ligaments and bone),decreased blood loss,and better overall proprioception.When UKA was first introduced in the 1970s,the outcomes of medial UKA(MUKA)were poor,but the few cases of lateral UKA(LUKA)showed promise.Since that time,there has been a relative paucity of literature focused specifically on LUKA given it is a rare procedure.Refinements in patient selection criteria,implant design,and surgical technique have been made leading to increased popularity.A review of the recent literature reveals that LUKA is associated with excellent long-term clinical outcomes and implant survivorship when performed in properly selected patients.Implant design options include fixed vs mobile bearing as well as metal backed vs all polyethylene tibial component,with improved outcomes noted with fixed bearing designs.Three reasons cited for revision(i.e.,fracture of the femoral component,fracture of the tibial component,and valgus malalignment)had been reported in past literature but not recently.Presently,while rare,the most common cause of failure and need for revision are osteoarthritis progression and aseptic loosening.Despite the need for an occasional revision procedure,the survivorship of LUKA is comparable to MUKA,although it should be noted that outcomes of MUKA have been notably varied.Continued pursuit of improved techniques and implant designs will continue to show LUKA to be an excellent procedure for appropriately indicated patients.

Unicompartmental Knee Arthroplasty: A Perspective from Computer Assisted Navigation

Unicompartmental Knee Arthroplasty (UKA) is an established procedure for the treatment of unicompartmental arthritis. Success depends on a clear understanding of the principles and kinematics of the knee. Restoration of the physiological axis and soft tissue balancing is the key to a successful outcome. We outline the basic principles of UKA and the role of computer assisted surgery in achieving these goals.

Determining the Effect of Deprivation on Quality of Life after Total and Unicompartmental Knee Arthroplasty

Determining the effect of deprivation on quality of life after total and unicompartmental knee arthroplasty Quality of life (QoL) following joint replacement is now a national priority, with every patient being assessed using the Oxford Knee Score. The current literature is conflicted as to whether deprivation has any effect on outcome after knee surgery. The type of surgery is another variable that may determine outcome. We set out to investigate which of these factors was a more powerful predictor of outcome. A prospective trial began where, 68 patients were telephoned, (30 TKA’s and 38 UKA’s). Each were asked a series of questions comprising the Oxford Knee Score (post operation), Imperial Knee Score (post operation), EuroQol-5D (pre and post operation) and individual deprivation questions. This was compared with the deprivation status using Townsend scores. A comparison of total and unicompartmental outcomes were also analysed including cost-effectiveness. No correlation was found between outcome and Townsend scores (p < 0.05). Age was seen to be a significant indicator of pre surgical QoL. However, a large and significant difference was found between UKA and TKA when using the EQ-5D (p < 0.05) and the Imperial Knee Score (p < 0.09). This was not reflected in the Oxford Knee Score. UKA’s were also found to be more cost-effective than TKA’s. Deprivation has no major effect on the outcome of knee surgery in London. A clear difference in efficacy exists between TKA’s and UKA’s. Sensitivity of scores needs to be addressed.

Internal fixation and unicompartmental knee arthroplasty for an elderly patient with patellar fracture and anteromedial osteoarthritis:A case report

BACKGROUND Open reduction and internal fixation(ORIF)is the traditional surgical treatment for patellar fractures,and unicompartmental knee arthroplasty(UKA),especially Oxford UKA,has been increasingly used in patients with medial knee osteoarthritis(OA).However,the process of choosing treatment for patients with both patellar fractures and anteromedial knee OA remains unclear.We present the case of a patient with a patellar fracture and anteromedial OA.CASE SUMMARY We present the case of a 72-year-old woman with a history of bilateral medial compartment OA of the knees and a right Oxford UKA.She also experienced a recent left patellar fracture.ORIF and Oxford UKA were performed in a single stage.The patient showed excellent postoperative clinical results.CONCLUSION ORIF and Oxford UKA can be performed simultaneously for patients with patellar fracture and anteromedial OA on the same knee.

<i>In vitro</i>measurement of tibiofemoral kinematics after patient-specific unicompartmental knee replacement

It is suggested that unicompartmental knee replacement (UKR) offers the potential to restore normal knee kinematics better than total knee replacement (TKR) because of retaining the cruciate ligaments, and better preservation of the overall geometry. It was hypothesized that patient-specific UKR would restore normal knee kinematics even better because of a customised articular shape. A comparative kinematics study was conducted on three cadaver limbs using two different test setups, a loaded ankle rig and an unloaded ankle rig. Kinematics was compared between a patient-specific UKR and a conventional fixed-bearing UKR. Both the UKRs showed similar kinematic patterns to the normal knee using both the test apparatus. The patient-specific UKR showed good results and with the other benefits it shows potential to dramatically improve clinical outcomes of knee replacement surgery.

Analysis of causes for revision in unicompartmental knee arthroplasty

The study by Zhao et al identifies the factors leading to the failure of unicompartmental knee arthroplasty(UKA)in their patients.These factors include substandard suturing of the wound,the presence of osteophytes and intra-articular loose bodies causing impingement,premature loosening of the tibial component,choosing unsuitable patients for the procedure,dislocation of the movable insert,and damage to the anterior cruciate ligament and medial collateral ligament.The findings suggest that employing the correct surgical techniques and indications is essential for successful outcomes in the UKA.

Insights into complications after unicompartmental knee arthroplasty

Zhao's study,offers a comprehensive analysis of unicompartmental knee arthroplasty(UKA)revision indications.The study provides a detailed,case-by-case analysis of the factors leading to knee revision surgery in 13 patients.Not only elucidates the complexities of UKA revisions but also underscores the importance of continuous improvement in surgical techniques and the adoption of innovative technologies.

Influence of patellofemoral joint degeneration on clinical outcomes after medial unicompartmental knee arthroplasty

Background:Patellofemoral joint(PFJ)degeneration has traditionally been regarded as a contraindication to unicompartmental knee arthroplasty(UKA).More recently,some researchers have proposed that PFJ degeneration can be ignored in medial UKA,and others have proposed that this change should be reviewed in PFJ degenerative facets and severity.This study aimed to systematically evaluate the effect of PFJ degeneration on patient-reported outcome measures(PROMs)and revision rates after medial UKA.Methods:Electronic databases(PubMed,Embase,Web of Science,etc.)were searched for studies assessing the influence of PFJ degeneration on medial UKA.A random-effects meta-analysis was conducted for the Oxford knee score(OKS),Knee society score(KSS),and revision rates and stratified by PFJ degenerative facets(medial/lateral/trochlear/unspecified),severe PFJ degeneration(bone exposed),and bearing type(mobile/fixed).Heterogeneity was assessed by the Cochran Q test statistic and chi-squared tests with the I-squared statistic.Results:A total of 34 articles with 7007 knees(2267 with PFJ degeneration)were included(5762 mobile-bearing and 1145 fixed-bearing and 100 unspecified).Slight to moderate degenerative changes in the medial and trochlear facets did not decrease the OKS and KSS,and only lateral facets significantly decreased the OKS(mean difference[MD]=-2.18,P<0.01)and KSS(MD=-2.61,P<0.01).The severity degree of PFJ degeneration had no additional adverse effect on the OKS,KSS,or revision rates.For mobile-bearing UKA,only lateral PFJ degeneration significantly decreased the OKS(MD=-2.21,P<0.01)and KSS(MD=-2.44,P<0.01).For fixed-bearing UKA,no correlation was found between PROMs/revision rates and PFJ degeneration.Conclusion:For medial mobile-bearing UKA,slight to moderate degenerative changes in the PFJ,except lateral facet,did not compromise PROMs or revision rates.For medial fixed-bearing UKA,although it might not be conclusive enough,PROMs or revision rates were not adversely affected by PFJ degeneration(regardless of the facet).

镜下前交叉韧带重建联合固定平台单髁置换术的早中期临床疗效观察

目的 探讨单髁置换手术(unicompartmental knee arthroplasty, UKA)联合前交叉韧带重建手术(anterior cruciate ligament reconstruction, ACLR)对单间室膝骨关节炎(unicompartmental knee osteoarthritis, UKOA)合并前交叉韧带缺失(anterior cruciate ligament deficient, ACLD)患者的早期临床疗效结果。方法 选取2018年1月至2022年6月广西中医药大学附属桂林市中医医院采用同期UKA联合ACLR治疗的UKOA合并ACLD的12例患者进行回顾性研究。评估术前和末次随访的VAS、IKDC、Lysholm评分,并随访观察并发症及翻修的发生情况。结果 所有患者随访6~55个月,平均随访(24.58±10.48)个月。所有患者的平均住院时间为(13.67±6.20)d,平均出血量为(43.33±39.44)mL,平均切口长度为(9.25±0.43)cm。末次随访时的VAS评分较术前明显降低(P<0.05);Lysholm评分平均为(67.17±22.96)分、IKDC评分平均为(59.87±8.77)分,分别较术前平均(51.33±14.99)分、(48.95±13.68)分明显提高(P<0.05)。结论 早中期的临床数据显示,同时进行ACLR联合UKA对UKOA合并ACLD手术治疗的临床疗效显著,可有效改善患者的膝关节不稳定和内侧间室疼痛,提高患者本体感觉,患者并发症发生率较低,值得临床推广应用,但应严格把握手术的适应证。

综合性干预对人工单髁膝关节置换患者术后关节功能恢复及满意度的影响

目的探讨综合性护理对人工单髁膝关节置换患者术后关节功能恢复和满意度的影响。方法选取2020年1月至2022年12月行人工单髁膝关节置换术的膝关节骨性关节炎患者60例,按照随机数字表法均分2组,每组30例。对照组予以常规护理,试验组予以综合性护理,对2组的护理成效进行对比分析。结果2组护理前的HSS评分无统计学意义(P>0.05),干预后试验组的HSS评分(92.83±3.47)分显著高于对照组的(80.93±3.28)分,2组比较差异有统计学意义(P<0.05),试验组术后在首次排气、首次排便、排便恢复至术前三方面的平均时间均短于对照组,差异有统计学意义(P<0.05),试验组和对照组的护理满意度分别为96.67%、73.33%,试验组高于对照组,差异有统计学意义(P<0.05),干预后试验组SF-36评分显著高于对照组(P<0.05)。结论对人工单髁膝关节置换术的患者实施综合性护理,能够明显改善患者的膝关节功能,促进胃肠道恢复,提高患者的护理满意度和生活质量,值得推荐。

UKA胫骨托盘背部设计对骨-假体固定界面的生物力学影响

目的研究UKA胫骨托盘背部设计对单髁膝关节置换(unicompartmental knee arthroplasty,UKA)骨-假体固定界面的生物力学影响。方法构建膝关节内侧置换的固定式UKA有限元模型,以膝关节行走运动下的关节载荷和关节运动为边界条件,对比研究大龙骨型、小龙骨型、两立柱带鳍骨型、三斜立柱型和三直立柱型UKA胫骨托盘背部设计下胫骨von Mises等效应力、骨-假体固定界面接触应力以及微动的差异。结果在膝关节内侧最大受力时刻,相对于两立柱带鳍骨型的胫骨von Mises等效应力、骨-假体固定界面接触应力和微动,大龙骨型分别减小8%和15.9%、增大9.9%;小龙骨型分别减小12.3%、增大7.5%和1.6%;三斜立柱型分别减小10%和10.5%、增大1.2%;三直立柱型分别减小7.7%、14.7%、1.6%。而骨-假体固定界面的最大微动发生在步态周期21%时刻,相对于两立柱带鳍骨型的骨-假体固定界面微动,大龙骨型增大1.2%,小龙骨型增大1.6%,三斜立柱型减小0.4%,三直立柱型减小2.3%。结论为了提高胫骨假体的长期固定效果,建议UKA胫骨托盘设计应重点考虑两直立柱带鳍骨或小龙骨的组合设计,从而有效地平衡应力传递和界面微动,在保证假体稳定性的同时降低无菌性松动的风险。

膝关节单髁置换术治疗单间室膝骨关节炎的临床效果

目的:探讨膝关节单髁置换术治疗单间室膝骨关节炎的效果。方法:选择2022年1月—2023年3月在福建中医药大学附属人民医院就诊的80例单间室膝骨关节炎患者作为研究对象,以随机数表法均分为对照组(应用全膝关节置换术治疗)及研究组(应用膝关节单髁置换术治疗),各40例。比较两组失血量、膝关节功能、炎症因子水平及并发症发生情况。结果:研究组隐性失血量、显性失血量、总失血量均少于对照组,差异有统计学意义(P<0.05)。术前,两组膝关节活动度、美国特种外科医院膝关节评分(HSS)、白细胞介素-8(IL-8)、趋化因子-5(CCL-5)、一氧化氮(NO)水平比较,差异无统计学意义(P>0.05);随访3个月后,两组膝关节活动度及HSS评分均高于术前,血清CCL-5、IL-8及NO水平均低于术前,且研究组膝关节活动度及HSS评分高于对照组,血清CCL-5、IL-8及NO水平均低于对照组,差异有统计学意义(P<0.05)。研究组并发症总发生率为0,低于对照组的15.00%,差异有统计学意义(P<0.05)。结论:与全膝关节置换术相比,膝关节单髁置换术在治疗单间室膝骨关节炎中更具优势,其损伤较小,可有效降低炎症因子水平及下肢深静脉栓塞风险,患者膝关节功能恢复更好。

复方倍他米松对坐骨神经联合股神经阻滞下膝关节单髁置换术后爆发痛的影响

目的探讨复方倍他米松对坐骨神经联合股神经阻滞下膝关节单髁置换术后爆发痛的影响。方法选择行单侧膝关节单髁置换术患者100例,男32例,女68例,年龄55~75岁,BMI 18.5~35.0 kg/m^(2),ASAⅠ—Ⅲ级。采用随机数字表法将患者分为三组:无佐剂组(C组,n=34)、地塞米松佐剂组(D组,n=33)和复方倍他米松佐剂组(B组,n=33)。麻醉诱导前三组行坐骨神经阻滞,注入0.4%罗哌卡因15 ml。之后再行股神经阻滞,C组注入0.4%罗哌卡因15 ml,D组注入0.4%罗哌卡因15 ml(含地塞米松5 mg),B组注入0.4%罗哌卡因15 ml(含复方倍他米松4 mg)。记录术后爆发痛发生情况、爆发痛评分、镇痛泵有效按压次数、阿片类药物用量和补救镇痛例数。记录术后0~24 h、24~48 h、48~72 h下地活动距离、睡眠质量评分以及不良事件发生情况。结果与C组比较,B组术后爆发痛发生率明显降低(P<0.05),镇痛泵有效按压次数、阿片类药物用量明显减少(P<0.05),补救镇痛率和术后第1晚睡眠质量评分明显降低(P<0.05)。与D组比较,B组术后爆发痛发生率和爆发痛评分明显降低(P<0.05),镇痛泵有效按压次数、阿片类药物用量明显减少(P<0.05),补救镇痛率和术后第1晚睡眠质量评分明显降低(P<0.05)。三组不同时间段下地活动距离、不良事件发生率差异无统计学意义。结论复方倍他米松佐剂可降低坐骨神经联合股神经阻滞下膝关节单髁置换术后爆发痛发生率,提供完善的镇痛效果,减少术后阿片类药物用量,提高患者术后第1晚睡眠质量。

单髁置换治疗膝关节内侧间室骨关节炎:关节功能及炎性细胞因子变化

背景:单髁置换因其创伤小、失血少、并发症少、康复快、膝关节功能优、假体生存率高等优点,越来越受到重视,相关报道多集中于其临床疗效,而单髁置换后患者体内相关炎性细胞因子的水平变化罕见报道。目的:探讨膝关节内侧间室骨关节炎患者单髁置换后的疗效及关节滑液白细胞介素1、白细胞介素6、肿瘤坏死因子α水平变化。方法:以2021年9月至2023年3月因膝内侧间室骨关节炎行单髁置换治疗并符合纳入标准的30例患者作为研究对象。比较术前、术后胫骨近端内侧角、股胫角、疼痛目测类比评分、美国特种外科医院膝关节评分、膝关节活动度及关节滑液白细胞介素1、白细胞介素6、肿瘤坏死因子α水平,并进行统计学分析。结果与结论:①30例患者术后切口均Ⅰ级愈合,术后均获6个月以上随访,所有患者均未出现假体松动、假体衬垫脱位等并发症;②术后1个月测量胫骨近端内侧角、股胫角均较术前明显改善(P<0.05);③术后1,3,6个月测量疼痛目测类比评分、美国特种外科医院膝关节评分、膝关节活动度均优于术前(P<0.05),术后各时间点呈逐渐好转趋势(P<0.05);④术后3,6个月测量关节滑液白细胞介素1、白细胞介素6、肿瘤坏死因子α水平均较术前逐渐下降(P<0.05),术后各时间点呈逐渐下降趋势;⑤提示单髁置换可有效治疗膝关节内侧间室骨关节炎,显著缓解患者疼痛,恢复膝关节功能,改善膝内翻畸形及下肢力线,并能在一定程度上降低关节内炎性细胞因子白细胞介素1、白细胞介素6、肿瘤坏死因子α的表达水平。

单间室与全膝关节置换术对膝骨关节炎患者楼梯行走时生物力学特征的影响

目的探究单间室膝关节置换术(unicompartmental knee arthroplasty,UKA)与全膝关节置换术(total knee arthroplasty,TKA)对膝骨关节炎术后的临床疗效。方法随机招募TKA患者21例、UKA患者15例。分别在术前以及术后6、12个月进行生物力学测试。采用Vicon红外动作捕捉系统和Kistler三维测力台同步采集受试者楼梯行走的运动学和动力学数据。结果在上楼梯时,TKA组受试者术前膝屈曲力矩峰值显著低于UKA组,术后6个月到达膝屈曲/内收力矩峰值时间、膝屈曲力矩冲量及膝内收力矩峰值负载率显著小于UKA组。在下楼梯时,UKA组术前和术后6个月伸膝功率峰值显著较小,垂直地面反作用力峰值负载率术前显著较大,膝伸展力矩峰值术后6个月显著较大;在术后12个月,楼梯行走的生物力学特征未出现明显的差异性。结论TKA组和UKA组在手术后表现出相似的膝关节功能,但TKA组可能采取不同于UKA组的下肢生物力学模式。在楼梯行走时,UKA组术后表现出更好的股四头肌控制能力,提高了楼梯行走尤其是下楼梯的姿势控制能力,而TKA组则采取保守的楼梯步态策略以降低楼梯行走的膝关节负荷。相比于力矩峰值,到达力矩峰值的时间及力矩峰值负载率是发现膝关节负荷差异性更灵敏的指标。

Finite Element Analysis of Mobile-bearing Unicompartmental Knee Arthroplasty： The Influence of Tibial Component Coronal Alignment

Background： Controversies about the rational positioning of the tibial component in unicompartmental knee arthroplasty （UKA） still exist. Previous finite element （FE） studies were rare, and the results varied. This FE study aimed to analyze the influence of the tibial component coronal alignment on knee biomechanics in mobile-bearing UKA and find a ration range of inclination angles. Methods： A three-dimensional FE model of the intact knee was constructed from image data of one normal subject. A 1000 N compressive load was applied to the intact knee model for validating. Then a set of eleven UKA FE models was developed with the coronal inclination angles of the tibial tray ranging from 10° valgus to 10° varus. Tibial bone stresses and strains, contact pressures and load distribution in all UKA models were calculated and analyzed under the unified loading and boundary conditions. Results： Load distribution, contact pressures, and contact areas in intact knee model were validated. In UKA models, von Mises stress and compressive strain at proximal medial cortical bone increased significantly as the tibial tray was in valgus inclination 〉4°, which may increase the risk of residual pain. Compressive strains at tibial keel slot were above the high threshold with varus inclination 〉4°, which may result in greater risk of component migration. Tibial bone resection comer acted as a strain-raiser regardless of the inclination angles. Compressive strains at the resected surface slightly changed with the varying inclinations and were not supposed to induce bone resorption and component loosening. Contact pressures and load percentage in lateral compartment increased with the more varus inclination, which may lead to osteoarthritis progression. Conclusions： Static knee biomechanics after UKA can be greatly affected by tibial component coronal alignment. A rauge from 4° valgus to 4° varus inclination oftibial component can be recommended in mobile-bearing UKA.