Prediction of the Biaxial Failure Strength of Composite Laminates with Unit Cell Analytic Model

A new method to predict the ultimate strength of fiber reinforced composites under arbitrary load condition is introduced. The micromechanics strength theory is used to perform the final failure prediction of composite laminates. The theory is based on unit cell analytic model which can provide the ply composite material properties by only using the constituent fiber and matrix properties and the laminate geometric parameters without knowing any experimental information of the laminates. To show that this method is suitable for predicting the strength of composite laminates, the micromechanics strength theory is ranked by comparing it with all the micro-level and the best two macro-level theories chosen from the World Wide Failure Exercise. The results show that this method can be used for predicting strength of any composite laminates and provide a direct reference for composite optimum design.

Unit Cell Modelling of Auxetic Structure

Auxetic material structures exhibit a negative Poisson ratio. The structure expands in the axial and transverse directions under tensile loading and vice versa under compression loading. Many fabricated designs for auxetic materials exist such as re-entrant hexagonal, chiral, and arrowhead geometries. This paper studies the unit cell of the re-entrant hexagonal geometry to understand how changing the internal angle and fillet radius of the structure affects the Poisson’s ratio. The material chosen for this study is acrylonitrile butadiene styrene (ABS) due to its availability and frequent use in additive manufacturing. The study was based on finite element analysis. It is observed that the direction of load applied to the unit cell affects the unit cell strain, Poisson’s ratio, and maximum load capacity before failure responses. It is noticed that the re-entrant cell starts by showing a standard non-auxetic behavior until it reaches a specific axial strain value. A quadratic correlation is identified between axial and transverse strain. Designing an auxetic structure starts with understanding the behavior of a unit cell structure. The auxetic structure design is a complex process that requires a compromise between auxetic property to be achieved and load capacity via avoiding stress concentration zones.

THE PRINCIPAL CONSTRUCTIVE PROCESS OF UNIT CELL IN Bi-BASED SUPERCONDUCTORS

In this paper, 2201 and 2212 phases as the corresponding precursor of forming 2212 and 2223 phases are discussed,and the constructive process of unit cell of 2201 phase is ascertained by XRD and chemical kinetics method. Subsequently, the process of 221

Elastic Predictions of 3D Orthogonal Woven Composites Using Micro/meso-scale Repeated Unit Cell Models

This presentation predicts the elastic properties of three-dimensional(3D)orthogonal woven composite(3DOWC)by finite element analysis based on micro/meso repeated unit cell(RUC)models.First,the properties of fiber yarn are obtained by analysis on a micro-scale RUC model assuming fibers in a hexagonal distribution pattern in the polymer matrix.Then a full thickness meso-scale RUC model including weft yarns,warp yarns,Z-yarns and pure resin zones is established and full stiffness matrix of the 3DOWC including the in-plane and flexural constants are predicted.For thick 3DOWC with large number of weft,warp layers,an alternative analysis method is proposed in which an inner meso-RUC and a surface meso-RUC are established,respectively.Then the properties of 3DOWC are deduced based on laminate theory and properties of the inner and surface layers.The predicted results by the above two alternative methods are in good experimental agreement.

Electronic Band Structure of Graphene Based on the Rectangular 4-Atom Unit Cell

The Wigner-Seitz unit cell (rhombus) for a honeycomb lattice fails to establish a k-vector in the 2D space, which is required for the Bloch electron dynamics. Phonon motion cannot be discussed in the triangular coordinates, either. In this paper, we propose a rectangular 4-atom unit cell model, which allows us to discuss the electron and phonon (wave packets) motion in the k-space. The present paper discusses the band structure of graphene based on the rectangular 4-atom unit cell model to establish an appropriate k-vector for the Bloch electron dynamics. To obtain the band energy of a Bloch electron in graphene, we extend the tight-binding calculations for the Wigner-Seitz (2-atom unit cell) model of Reich et al. (Physical Review B, 66, Article ID: 035412 (2002)) to the rectangular 4-atom unit cell model. It is shown that the graphene band structure based on the rectangular 4-atom unit cell model reveals the same band structure of the graphene based on the Wigner-Seitz 2-atom unit cell model;the π-band energy holds a linear dispersion (ε−k ) relations near the Fermi energy (crossing points of the valence and the conduction bands) in the first Brillouin zone of the rectangular reciprocal lattice. We then confirm the suitability of the proposed rectangular (orthogonal) unit cell model for graphene in order to establish a 2D k-vector responsible for the Bloch electron (wave packet) dynamics in graphene.

Theoretical aspects of selecting repeated unit cell model in micromechanical analysis using displacement-based finite element method

Repeated Unit Cell（RUC）is a useful tool in micromechanical analysis of composites using Displacement-based Finite Element（DFE）method,and merely applying Periodic Displacement Boundary Conditions（PDBCs）to RUC is almost a standard practice to conduct such analysis.Two basic questions arising from this practice are whether Periodic Traction Boundary Conditions（PTBCs,also known as traction continuity conditions）are guaranteed and whether the solution is independent of selection of RUCs.This paper presents the theoretical aspects to tackle these questions,which unify the strong form,weak form and DFE method of the micromechanical problem together.Specifically,the solution’s independence of selection of RUCs is dealt with on the strong form side,PTBCs are derived from the weak form as natural boundary conditions,and the validity of merely applying PDBCs in micromechanical Finite Element（FE）analysis is proved by referring to its intrinsic connection to the strong form and weak form.Key points in the theoretical aspects are demonstrated by illustrative examples,and the merits of setting micromechanical FE analysis under the background of a clear theoretical framework are highlighted in the efficient selection of RUCs for Uni Directional（UD）fiber-reinforced composites.

Direct evidence of high temperature superconductivity in one-unit-cell FeSe films on SrTiO_3 substrate by transport and magnetization measurements

Zero resistance and Meissner effect are two crucial experimental evidences of superconductivity in determining a new kind of superconductor, which can be detected by transport and diamagnetic measurements. In this paper, we briefly review the main transport and magnetization results on the one unit cell （1-UC） FeSe films grown on SrTiO3 （STO） substrates from our team in recent years, which identify the high temperature superconductivity in 1-UC FeSe films.

THE CONFIGURATION OF QUASICRYSTAL UNIT CELL AND DEDUCTION OF QUASILATTICE

From the crystal chemistry and icosahedral phase, two kinds of coordinational polyhedron with 8-fold rotational symmetry——hexakaicahedra and bicapped antiprism were possibly suggested and their one- and two-dimensional quasilattices were deducted. According to the principle of Bravais in conventional crystallography, four kinds of two-dimensional unit cell have been defined in 5, 8, 10, 12-fold rotational symmetry quasicrystal. The authors considered that quasicrystal is a kind of crystal which possesses an incommensurable translational period. This kind of translation is carried out by inflation or deflation symmetry operation.

Preparation of patterned boron nanowire films with different widths of unit-cell and their field emission properties

Large-area patterned films of boron nanowires（BNWs） are fabricated at various densities by chemical vapor deposition（CVD）. Different widths of unit-cell of Mo masks are used as templates. The widths of unit-cell of Mo masks are100 μm, 150 μm, and 200 μm, respectively. The distance between unit cells is 50 μm. The BNWs have an average diameter of about 20 nm and lengths of 10 μm–20 μm. High-resolution transmission electron microscopy analysis shows that each nanowire has a β-tetragonal structure with good crystallization. Field emission measurements of the BNW films show that their turn-on electric fields decrease with width of unit-cell increasing.

Application of Solid Oxide Fuel Cell-Auxiliary Power Unit on Different Trucks in Northeast China

A diesel engine of conventional trucks has a low efficiency under the idling condition,leading to a high cost for heating or cooling in the cab during night. The solution to this problem will have great significance on energy conservation and emission reduction. A new auxiliary power unit of solid oxide fuel cell( SOFCAPU) with high efficiency solves this problem perfectly. Heat pump air conditioner is considered as a promising device for the application of SOFC-APU with a high cooling and heating efficiency. To make a quantitative analysis for the application of SOFC-APU,a model is built in Matlab / Simulink. The diesel engine model and SOFC-APU model are fitted based on some experimental data of SOFC-APU and diesel engine during the idling operation. An analysis of the application of SOFC-APU on different trucks in Northeast China is comprehensively made,including efficiency and emission.

Hierarchy of mesenchymal stem cells: Comparison of multipotentmesenchymal stromal cells with fibroblast colony forming units

The organization of the compartment of mesenchymal stem cells is still obscure. Two types of human stromal precursor cells are known. Both of them are analyzed in in vitro system: mesenchymal multipotent stromal cells (MMSC) and fibroblast colony forming units (CFU-F). The aim of this study was to compare the main characteristics of MMSC and CFU-F derived from the bone marrow of 24 healthy donors. Growth and differentiation parameters, as well as relative expression levels of different genes were analyzed in MMSC and CFU-F. MMSC were cultivated for 5 passages. CFU-F concentration was determined for each bone marrow sample. The data obtained demonstrated the heterogeneity and hierarchical organization of both studied populations of stromal precursor cells-MMSC and CFU-F. These two types of stromal precursor cells turned to be different in most parameters studied. Altogether MMSC seemed to be more immature cells than CFU-F and took up the higher position in hierarchical tree of mesenchymal stem cells. The rate of differentiation and proliferative potential decreased with the donor’s age in both populations MMSC and CFU-F.

Industrial Preparation and Acid Resistance of Ultra-stable Y Zeolite with Small Cell Size Produced by Gas-phase Method

Small-cell HSY-S zeolite prepared by the gas-phase ultra-stable method had been researched and developed,and industrial preparation tests of HSY-S have been successfully carried out for the first time.The acid resistance of industrially prepared HSY-S was investigated by acid solutions with different pH values.The structures and properties of HSY-S and its acid-treated samples were characterized by XRD,XRF,BET,and IR.Results show that the HSY-S samples have the characteristics of high crystallinity,good stability,large specific surface area,and good acid resistance.

基于密度泛函理论的蒽醌太赫兹吸收光谱模拟

蒽醌是一种平面结构的具有大环共扼体系的有机化合物,在染料、造纸、生物和医药等众多行业有着广泛的应用。为研究蒽醌在太赫兹频段的特征吸收和其分子晶体结构之间的关系,基于密度泛函理论(DFT)并利用太赫兹时域光谱(THz-TDS)技术对蒽醌晶体的太赫兹吸收谱进行了理论模拟和实验研究。首先利用THz-TDS系统测量了室温下蒽醌晶体在0.5~3.0 THz频段的特征吸收谱,发现蒽醌晶体在该频段内有6个明显的特征吸收峰,分别位于0.95,1.05,2.09,2.25,2.49和2.78 THz处。为深入解析蒽醌在太赫兹频段实验特征谱的产生机理,基于密度泛函理论分别对蒽醌单分子模型和晶胞模型进行了理论模拟计算。使用Gaussian09软件对蒽醌单分子模型进行的理论计算,采用了基于DFT的B3LYP杂化泛函方法和6-311G(d,p)基组,几何结构优化和振动频率计算在相同水平上进行,模拟计算结果与实验测量数据存在明显的差异,说明单分子模拟存在一定的局限性。使用MS8.0软件包中适合计算周期性结构的CASTEP模块对蒽醌晶胞模型进行理论计算,采用了基于平面波赝势和广义梯度近似(GGA)的PBE、PW91,WC,PBEsol和RPBE五种交换相关泛函,几何结构优化和晶格动力学计算在相同水平上进行。将蒽醌单分子和晶胞的理论模拟结构参数(键长、键角)分别与其X射线衍射实验测量的结构参数进行了详细的比较分析,发现基于PBE方法获得的固态仿真结果中分子的结构参数与X射线衍射实验数据的一致性最好。同时用PBE和RPBE方法获得的理论仿真谱与实验吸收谱比较吻合。因此,基于PBE和RPBE的计算结果对实验特征吸收峰进行了振动模式指认。研究结果表明,蒽醌晶体在太赫兹频段的特征吸收主要来源于晶体中由C—H…O分子内氢键主导的蒽醌环和苯环基团的整体振动以及由分子间弱相互作用引发的集体振动模式。

PCT、WBC联合CRP在ICU呼吸感染中的表达、诊断价值及与CPIS评分的相关性分析

目的分析降钙素原(PCT)、白细胞计数(WBC)联合C反应蛋白(CRP)在重症监护室(ICU)呼吸感染中的表达、诊断价值及与临床肺部感染评分(CPIS)的相关性。方法选取2019年3月至2024年6月涿州市医院ICU呼吸感染患者105例为观察组,另外选取于ICU未发生呼吸感染117例患者为对照组。通过Zybio-Q7型免疫定量分析仪对两组PCT水平进行检测,通过XT-4000i型白细胞分析仪对两组WBC水平进行检测,通过免疫比浊法对两组CRP水平进行检测。分析PCT、WBC、CRP的表达变化与ICU呼吸感染临床特征、CPIS评分的关系及对ICU呼吸感染的诊断价值。结果观察组入住ICU时间(>15 d)和机械通气时间(>7 d)的占比显著高于对照组(P<0.05)。与对照组比较,观察组PCT、WBC、CRP水平和CPIS评分升高,差异具有统计学意义(P<0.05)。多因素Logistic回归分析结果显示,入住ICU时间>15 d(OR=4.087)、PCT(OR=6.543)、WBC(OR=2.652)和CRP(OR=8.964)为影响ICU呼吸感染发生的危险因素。PCT、WBC、CRP与CPIS评分之间Pearson相关性分析显示,PCT、CPIS评分之间正相关(r=0.925,P=0.001);WBC、CPIS评分之间正相关(r=0.739,P=0.001);CRP、CPIS评分之间正相关(r=0.948,P=0.001)。ROC曲线显示,三项联合对ICU呼吸感染的诊断价值高于PCT、WBC、CRP单项诊断(P=0.002)。结论PCT、WBC联合CRP对ICU呼吸感染的诊断价值较高,且与CPIS评分呈正相关,因此上述指标可为ICU呼吸感染的早期诊断提供可靠依据。

Accurate Symbolic Solution of Ginzburg-Landau Equations in the Circular Cell Approximation by Variational Method: Magnetization of Ideal Type II Superconductor

In this paper I access the degree of approximation of known symbolic approach to solving of Ginzburg-Landau (GL) equations using variational method and a concept of vortex lattice with circular unit cells, refine it in a clear and concise way, identify and eliminate the errors. Also, I will improve its accuracy by providing for the first time precise dependencies of the variational parameters;correct and calculate magnetisation, compare it with the one calculated numerically and conclude they agree within 98.5% or better for any value of the GL parameter k and at magnetic field , which is good basis for many engineering applications. As a result, a theoretical tool is developed using known symbolic solutions of GL equations with accuracy surpassing that of any other known symbolic solution and approaching that of numerical one.

Structural and functional damage to the hippocampal neurovascular unit in diabetes-related depression

Previous studies have shown that models of depression exhibit structural and functional changes to the neurovascular unit. Thus, we hypothesized that diabetes-related depression might be associated with damage to the hippocampal neurovascular unit. To test this hypothesis, neurons, astrocytes and endothelial cells were isolated from the brain tissues of rat embryos and newborn rats. Hippocampal neurovascular unit co-cultures were produced using the Transwell chamber co-culture system. A model of diabetes-related depression was generated by adding 150 mM glucose and 200 μM corticosterone to the culture system and compared with the neuron + astrocyte and astrocyte + endothelial cell co-culture systems. Western blot assay was used to measure levels of structural proteins in the hippocampal neurovascular unit co-culture system. Levels of basic fibroblast growth factor, angiogenic factor 1, glial cell line–derived neurotrophic factor, transforming growth factor β1, leukemia inhibitory factor and 5-hydroxytryptamine in the hippocampal neurovascular unit co-culture system were measured by enzyme-linked immunosorbent assay. Flow cytometry and terminal deoxynucleotidyl transferase(TdT)-mediated dUTP nick end labeling staining was used to assess neuronal apoptosis in the hippocampal neurovascular unit. The neurovascular unit triple cell co-culture system had better barrier function and higher levels of structural and secretory proteins than the double cell co-culture systems. In comparison, in the model of diabetes-related depression, the neurovascular unit was damaged with decreased barrier function, poor structural integrity and impaired secretory function. Moreover, neuronal apoptosis was markedly increased, and 5-hydroxytryptamine levels were reduced. These results suggest that diabetes-related depression is associated with structural and functional damage to the neurovascular unit. Our findings provide a foundation for further studies on the pathogenesis of diabetes-related depression.

Neuronal-like cell differentiation of non-adherent bone marrow cell-derived mesenchymal stem cells

Non-adherent bone marrow cell-derived mesenchymal stem cells from C57BL/6J mice were sepa- rated and cultured using the ＂pour-off＂ method. Non-adherent bone marrow cell-derived mesen- chymal stem ceils developed colony-forming unit-fibroblasts, and could be expanded by supple- mentation with epidermal growth factor. Immunocytochemistry showed that the non-adherent bone marrow cell-derived mesenchymal stem cells exposed to basic fibroblast growth factor/epidermal growth factor/nerve growth factor expressed the neuron specific markers, neurofilament-200 and NeuN, in vitro. Non-adherent bone marrow cell-derived mesenchymal stem cells from 13-galactosidase transgenic mice were also transplanted into focal ischemic brain （right corpus striatum） of C57BL/6J mice. At 8 weeks, cells positive for LacZ and 13-galactosidase staining were observed in the ischemic tissues, and cells co-labeled with both 13-galactosidase and NeuN were seen by double immunohistochemical staining. These findings suggest that the non-adherent bone marrow cell-derived mesenchymal stem cells could differentiate into neuronal-like cells in vitro and in vivo.

Epithelial cell identity in hyperplastic precursors of breast cancer

Introduction:In the adult human breast,hyperplastic enlarged lobular unit(HELU) and atypical ductal hyperplasia(ADH) are two common abnormalities that frequently coexist with ductal carcinoma in situ(DCIS).For this reason,they have been proposed as the early steps in a biological continuum toward breast cancer.Methods:We investigated in silico the expression of 369 genes experimentally recognized as involved in establishing and maintaining epithelial cell identity and mammary gland remodeling,in HELUs or ADHs with respect to the corresponding patient-matched normal tissue.Results:Despite the common luminal origin,HELUs and ADHs proved to be characterized by distinct gene profiles that overlap for 5 genes only.While HELUs were associated with the overexpression of progesterone receptor(PGR),ADHs were characterized by the overexpression of estrogen receptor 1(ESR1) coupled with the overexpression of some proliferation-associated genes.Conclusions:This unexpected finding contradicts the notion that in differentiated luminal cells the expression of estrogen receptor(ER) is dissociated from cell proliferation and suggests that the establishing of an ER-dependent signaling is able to sustain cell proliferation in an autocrine manner as an early event in tumor initiation.Although clinical evidence indicates that only a fraction of HELUs and ADHs evolve to invasive cancer,present findings warn that exposure to synthetic progestins,frequently administered as hormone-replacement therapy,and estrogens,when abnormally produced by adipose cells and persistently present in the stroma surrounding the mammary gland,may cause these hyperplastic lesions.

血清sTLT-1、ESM-1对ICU患者发生输血相关急性肺损伤的诊断价值

目的 分析血清可溶性髓样细胞触发受体样转录因子-1(sTLT-1)、内皮细胞特异性分子-1(ESM-1)对重症监护病房(ICU)患者输血相关急性肺损伤(TRALI)的诊断价值。方法 选取2021年8月至2023年8月在该院ICU进行输血治疗的289例患者作为研究对象,依据是否发生TRALI将患者分为TRALI组(58例)和非TRALI组(231例)。采用酶联免疫吸附试验检测血清sTLT-1、ESM-1、白细胞介素(IL)-8、IL-6、IL-1水平。采用Pearson相关分析TRALI组患者血清sTLT-1、ESM-1水平与肺损伤预测(LIPS)评分、序贯器官衰竭(SOFA)评分、急性生理学与慢性健康评价Ⅱ(APACHEⅡ)评分及氧合指数的相关性。绘制受试者工作特征(ROC)曲线分析血清sTLT-1、ESM-1对ICU患者发生TRALI的诊断价值。结果 TRALI组血清sTLT-1、ESM-1、IL-8、IL-6、IL-1水平均高于非TRALI组患者,差异均有统计学意义(P<0.05)。Pearson相关分析结果显示,TRALI组患者血清sTLT-1、ESM-1水平与LIPS、SOFA、APACHEⅡ评分呈正相关,与氧合指数呈负相关。ROC曲线分析结果显示,sTLT-1、ESM-1单独诊断ICU患者发生TRALI的曲线下面积(AUC)分别为0.852、0.809,2项指标联合诊断ICU患者发生TRALI的AUC为0.934。2项指标联合诊断的AUC显著大于sTLT-1、ESM-1单独诊断的AUC(Z=3.519、3.836,P<0.001)。结论 ICU患者发生TRALI前,患者血清sTLT-1、ESM-1水平升高,且其与患者肺损伤严重程度密切相关,sTLT-1、ESM-1联合检测对ICU患者发生TRALI的诊断价值较高。

单一应力下义马原煤热解产物演变规律及动力学模拟

以义马原煤为研究对象,构造晶胞,在ReaxFF力场中施加5×10^(9)s^(-1)的应变率,模拟1000K,1500K,2000K,2500K,3000K终温下义马原煤热解演化过程,分析单一应力对褐煤热解的作用效果。结果表明:不同模拟终温下,不同方向上的应力是上下波动的,在允许一定误差下,应力范围保持在±70GPa之间,即此应力对褐煤热解的作用受温度的影响较弱。模拟过程中,在26ps~33ps之间分子数出现极小值点而种类数出现极大值点,义马原煤热解模拟起始温度点不变,但缩聚反应的温度区间前移,表明反应前期单一应力作用效果优于温度作用效果,应力促进了整体的反应进程。受缩聚反应的影响,CO,CH_(4),H_(2)O和NH_(3)含量先升后降,符合热解一般规律,说明应力没有改变反应的最终趋势。H_(2)和·H的数量随反应进行持续上升,说明缩聚反应过程中,此应力作用促进焦油裂解生成的·H的数量大于缩聚反应消耗的·H的数量;同时,·H和H_(2)含量升高,促进·SH与·H结合,提高了H_(2)S的产率。