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A Study of the Universal Two-child Policy’s Impact on China’s Future Population
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作者 Zhai Zhenwu Li Long Chen Jiaju 《Contemporary Social Sciences》 2016年第2期100-115,共16页
The most essential step in adjusting and improving the childbearing policy, the universal two-child policy will produce far-reaching impacts on the future development of China’s population. With its implementation, t... The most essential step in adjusting and improving the childbearing policy, the universal two-child policy will produce far-reaching impacts on the future development of China’s population. With its implementation, the country’s total population will peak later, the underage population and its proportion will increase substantially, the working-age population will experience a slower decline, and the aging of China’s population will be eased. However, the drop in the proportion of working-age people over the last 15 years has expedited the reduction of the demographic dividend, the elderly population will remain unaffected over the next 60 years, the aging of the population will continue to deepen, and at the same time, the increased child dependency burden will expand the overall dependency ratio. 展开更多
关键词 the universal two-child policy underage POPULATION working-age POPULATION the aging of the POPULATION family planning DEMOGRAPHIC structure DEMOGRAPHIC DIVIDEND
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Study on the Influence of the the Universal Two-childPolicy on China's Pension Payment
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作者 YANG Li 《International English Education Research》 2018年第4期74-75,共2页
In the face of the continuous decline in the birth rate and the aging of the peak of aging, following the implementation of the "Decision of the Central Committee of the Communist Party of China on Comprehensively De... In the face of the continuous decline in the birth rate and the aging of the peak of aging, following the implementation of the "Decision of the Central Committee of the Communist Party of China on Comprehensively Deepening the Reform of Some Major Issues" adopted by the Filth Plenary Session of the 18th CPC Central Committee on November 15, 2013, the party is the only child. Female couples can have a policy of giving birth to two children. On October 29, 2015, China introduced the "two-child policy", completely replacing the "one-child policy" that has been implemented in China for more than 30 years. The "two-child comprehensive" can alleviate the unfavorable population trend that plagues China's social security system to a certain extent. Optimize the age structure of the population and increase the supply of labor. However, for a long time, the financial distress and management dilemma faced by China's pension payment still exist, and the loose population birth policy will have a great impact on reducing pension payment, and will gradually appear in the policy implementation. This article combines the "comprehensive two-child" policy, focusing on the role of the new population birth policy to alleviate the pressure on China's pension. 展开更多
关键词 Fertility policy adjustment two-child policy PENSION
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CPC Central Committee and the State Council Issued the Decision to Specify the “Key Points” of the Universal Two-child Policy
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作者 Wu Jiajia 《China Population Today》 2016年第1期43-44,共2页
The Decision of CPC Central Committee and the State Council on Full Implementation of the Universal Two-child policy and Innovation and Improvement of Family Planning Service Management(Hereinafterreferred to as the ... The Decision of CPC Central Committee and the State Council on Full Implementation of the Universal Two-child policy and Innovation and Improvement of Family Planning Service Management(Hereinafterreferred to as the Decision)was announced on January 5,2016.China will implement a birth registration service system. 展开更多
关键词 registration Family birth giving Key Points universal encourage collective interacting parties
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Floquet spectrum and universal dynamics of a periodically driven two-atom system
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作者 谢文柱 周正强 +2 位作者 李轩 崔思淼 孙明远 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第2期436-443,共8页
We investigate the Floquet spectrum and excitation properties of a two-ultracold-atom system with periodically driven interaction in a three-dimensional harmonic trap.The interaction between the atoms is changed by va... We investigate the Floquet spectrum and excitation properties of a two-ultracold-atom system with periodically driven interaction in a three-dimensional harmonic trap.The interaction between the atoms is changed by varying the s-wave scattering length in two ways,the cosine and the square-wave modulations.It is found that as the driving frequency increases,the Floquet spectrum exhibits two main features for both modulations,the accumulating and the spreading of the quasienergy levels,which further lead to different dynamical behaviors.The accumulation is associated with collective excitations and the persistent growth of the energy,while the spread indicates that the energy is bounded at all times.The initial scattering length,the driving frequency and amplitude can all significantly change the Floquet spectrum as well as the dynamics.However,the corresponding relation between them is valid universally.Finally,we propose a mechanism for selectively exciting the system to one specific state by using the avoided crossing of two quasienergy levels,which could guide preparation of a desired state in experiments. 展开更多
关键词 Floquet spectrum universal dynamics two-atom system avoided crossing
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Evaluating the Impact of the Universal Test and Treat Strategy on the Survival of Patients in the Northwest Region of Cameroon
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作者 Emmanuel Mboh Nshom Bereynuy Jude Cholong +9 位作者 Kum Kang Walter Khan Eveline Mboh Keng Vitalis Noela F. Ijang Gwendoline Nkenu Nsom Mirabel Mbueh Vifeme Esther Bonje Kuni Monju Johnson Vishi Gladys Enih Fosah Pius Muffih Tih 《World Journal of AIDS》 2024年第3期45-60,共16页
Introduction: The main outcome of efficiently implemented universal test and treat (UTT) program is improved survival. UTT implementation has been ongoing in Cameroon since 2016 but evaluation data are scarce. This st... Introduction: The main outcome of efficiently implemented universal test and treat (UTT) program is improved survival. UTT implementation has been ongoing in Cameroon since 2016 but evaluation data are scarce. This study aims to assess the survival of antiretroviral therapy (ART) patients initiated under UTT in Northwest region of Cameroon. Methods: This retrospective cohort study included HIV-positive patients initiated in 2016 at 27 purposefully selected sites and followed until 2021. Data was anonymously abstracted from ART registers and patients’ charts. Kaplan-Meier survival estimates and Cox model were used to compare the survival of patients initiated under UTT with those initiated otherwise, using stata version 14.0. Results: In total, 2490 HIV-positive patients (median age 42.7 years, 94.7% adults, and 69.0% female) participated in the study. Of 1389 patients with viral load (VL) test results, 55% were initiated on ART late. The VL suppression rate of patients initiated late and those initiated early were similar. During follow-up, 1020 (40.9%) participants censored. The survival curves of patients initiated early on ART and those initiated late were similar during the first 2.5 years of follow-up but significantly (p Conclusions: This study confirms the expected impact of UTT. Programs only need to close existing implementation gaps along the critical pathways (diagnosis and treatment) of UTT, focusing more on males. 展开更多
关键词 universal Test and Treat Viral Load SURVIVAL NORTHWEST Cameroon
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Information Conductivity:Universal Performance Measure for Semantic Communications
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作者 Liang Zijian Niu Kai Zhang Ping 《China Communications》 SCIE CSCD 2024年第7期17-36,共20页
As a novel paradigm,semantic communication provides an effective solution for breaking through the future development dilemma of classical communication systems.However,it remains an unsolved problem of how to measure... As a novel paradigm,semantic communication provides an effective solution for breaking through the future development dilemma of classical communication systems.However,it remains an unsolved problem of how to measure the information transmission capability for a given semantic communication method and subsequently compare it with the classical communication method.In this paper,we first present a review of the semantic communication system,including its system model and the two typical coding and transmission methods for its implementations.To address the unsolved issue of the information transmission capability measure for semantic communication methods,we propose a new universal performance measure called Information Conductivity.We provide the definition and the physical significance to state its effectiveness in representing the information transmission capabilities of the semantic communication systems and present elaborations including its measure methods,degrees of freedom,and progressive analysis.Experimental results in image transmission scenarios validate its practical applicability. 展开更多
关键词 information conductivity information transmission capability semantic communications system model universal performance measure
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Enhanced Temporal Correlation for Universal Lesion Detection
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作者 Muwei Jian Yue Jin Hui Yu 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第3期3051-3063,共13页
Universal lesion detection(ULD)methods for computed tomography(CT)images play a vital role in the modern clinical medicine and intelligent automation.It is well known that single 2D CT slices lack spatial-temporal cha... Universal lesion detection(ULD)methods for computed tomography(CT)images play a vital role in the modern clinical medicine and intelligent automation.It is well known that single 2D CT slices lack spatial-temporal characteristics and contextual information compared to 3D CT blocks.However,3D CT blocks necessitate significantly higher hardware resources during the learning phase.Therefore,efficiently exploiting temporal correlation and spatial-temporal features of 2D CT slices is crucial for ULD tasks.In this paper,we propose a ULD network with the enhanced temporal correlation for this purpose,named TCE-Net.The designed TCE module is applied to enrich the discriminate feature representation of multiple sequential CT slices.Besides,we employ multi-scale feature maps to facilitate the localization and detection of lesions in various sizes.Extensive experiments are conducted on the DeepLesion benchmark demonstrate that thismethod achieves 66.84%and 78.18%for FS@0.5 and FS@1.0,respectively,outperforming compared state-of-the-art methods. 展开更多
关键词 universal lesion detection computational biology medical computing deep learning enhanced temporal correlation
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Extensive numerical simulations on competitive growth between the Edwards–Wilkinson and Kardar–Parisi–Zhang universality classes
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作者 余成志 刘潇 +1 位作者 唐军 夏辉 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第6期298-307,共10页
Extensive numerical simulations and scaling analysis are performed to investigate competitive growth between the linear and nonlinear stochastic dynamic growth systems, which belong to the Edwards–Wilkinson(EW) and K... Extensive numerical simulations and scaling analysis are performed to investigate competitive growth between the linear and nonlinear stochastic dynamic growth systems, which belong to the Edwards–Wilkinson(EW) and Kardar–Parisi–Zhang(KPZ) universality classes, respectively. The linear growth systems include the EW equation and the model of random deposition with surface relaxation(RDSR), the nonlinear growth systems involve the KPZ equation and typical discrete models including ballistic deposition(BD), etching, and restricted solid on solid(RSOS). The scaling exponents are obtained in both the(1 + 1)-and(2 + 1)-dimensional competitive growth with the nonlinear growth probability p and the linear proportion 1-p. Our results show that, when p changes from 0 to 1, there exist non-trivial crossover effects from EW to KPZ universality classes based on different competitive growth rules. Furthermore, the growth rate and the porosity are also estimated within various linear and nonlinear growths of cooperation and competition. 展开更多
关键词 competitive growth scaling behavior discrete growth model Kardar–Parisi–Zhang universality class
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Sci-tech Simultaneous Interpreter Education Based on Translation Universals Research
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作者 JI Mengqi JI Xiaowen 《Sino-US English Teaching》 2024年第9期443-448,共6页
The rapid evolution of scientific and technological advancements and industrial changes has profoundly interconnected countries and regions in the digital information era,creating a globalized environment where effect... The rapid evolution of scientific and technological advancements and industrial changes has profoundly interconnected countries and regions in the digital information era,creating a globalized environment where effective communication is paramount.Consequently,the demand for proficient interpreting skills within the scientific and technology sectors has surged,making effective language communication increasingly crucial.This paper explores the potential impact of translation universals on enhancing sci-tech simultaneous interpreter education.By examining the selection of teaching materials,methods,and activities through the lens of translation universals,this study aims to improve the quality of teaching content,innovate instructional approaches,and ultimately,enhance the effectiveness of interpreter education.The findings of this research are expected to provide valuable insights for curriculum development and pedagogical strategies in interpreter education. 展开更多
关键词 simultaneous interpreting translation universals interpreter education sci-tech interpreting
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From the Subjectivity of Human Rights to the Universality of Human Rights——A Preliminary Interpretation of the Theory on the Subjectivity of Human Rights
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作者 HUANG Jinrong 《The Journal of Human Rights》 2024年第3期709-733,共25页
Universality is one of the essential characteristics of human rights, but there is a substantive difference between idealism and realism in understanding the concept of universality of human rights. The concepts of ra... Universality is one of the essential characteristics of human rights, but there is a substantive difference between idealism and realism in understanding the concept of universality of human rights. The concepts of radical universality and strong universality based on the concept of natural human rights are too idealistic and thus have a high risk of being alienated into a tool of international re-pression in practice. On the contrary, the theory on the subjectivity of human rights can effectively defuse this risk brought about by radical universality and strong universality. Advocating a transition from the universality of human rights to the subjectivity of human rights not only keeps in line with the actual construction process of international human rights, but can also effectively interpret the practical difficul-ties in the realization process of international human rights. Therefore, it can be used as another alternative theory on human rights beyond the theory of natural human rights. 展开更多
关键词 human rights universalITY SUBJECTIVITY concept of natural human rights
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Introducing a 2nd Universal Space-Time Constant Can Explain the Observed Age of the Universe and Dark Energy
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作者 Herman A. van Hoeve 《World Journal of Mechanics》 2024年第2期9-22,共14页
The purpose of this paper is to introduce new theoretical concepts as opposed to accepting the existence of dark entities, such as dark energy. This research sought to introduce a 2<sup>nd</sup> universal ... The purpose of this paper is to introduce new theoretical concepts as opposed to accepting the existence of dark entities, such as dark energy. This research sought to introduce a 2<sup>nd</sup> universal space-time constant, besides having a finite speed constant (speed of light in vacuum c). A finite universal age constant b is introduced. Namely, this paper shows that the changes in the Earth’s anomalistic year duration over time support the hypothesis of the age of the universe correlating with a maximum number of orbital revolutions constant. Neglecting the gravitational influence of other cosmological entities in the proximity of the Earth, the constant maximum number of revolutions is herewith determined solely by the Earth’s orbital revolutions around the Sun. The value of the universal age constant b is calculated to be around 13.8 billion orbital revolutions, derived out of an equation related to the changes in the Earth’s anomalistic year duration over time and the so-called Hubble tension. The above-mentioned calculated value b correlates well with the best fit to measured data of the cosmic microwave background radiation (CMBR) by the Planck spacecraft, the age of the observed universe is measured to be approximately 13.787 ± 0.020 billion years (2018 final data release). Developing a theory with this 2<sup>nd</sup> universal space-time constant b, being covariant with respect to the Lorentz transformations when time spans are large, gives results such as: A confirmation of the measured CMBR value of 13.787 ± 0.020 billion years. Correlating well with the observed expansion rate of the universe (dark energy). The universe’s expansion accelerating over the last four to five billion years. 展开更多
关键词 Anomalistic Year Orbital Revolution Hubble Tension Age of the universe Cosmological Constant Dark Energy Cosmic Microwave Background
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Development and Optimization of Universal Bone Conduction Hearing Spectacles
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作者 Johannes Burkart Mona Kirstin Fehling +2 位作者 Saadu Adamu Raúl Pérez Ramos Daniel Häussler 《International Journal of Otolaryngology and Head & Neck Surgery》 2024年第5期344-358,共15页
Background: Non-implantable bone anchored hearing devices (BCHDs) are utilized for patients with conductive or mixed hearing loss who are unsuitable for conventional hearing aids or have unresolved middle ear issues. ... Background: Non-implantable bone anchored hearing devices (BCHDs) are utilized for patients with conductive or mixed hearing loss who are unsuitable for conventional hearing aids or have unresolved middle ear issues. These devices can be surgically implanted or attached using adhesive plates, dental sticks, elastic headbands, or bone conduction spectacles. Optimal fitting of bone conduction spectacles requires appropriate frame selection and contact pressure in the temporal and mastoid areas. The ANSI S3.6 and DIN EN ISO 389-3 standards recommend a contact area of approximately 1.75 cm2 and a maximum force of 5.4 N for effective sound transmission and comfort. Methods: This study aimed to evaluate the technical fit and mechanical stability of universal bone conduction hearing spectacles compared to established systems. A Sen-Pressure 02 thin-film sensor connected to an Arduino Uno R3 board measured contact force in the temporal and mastoid areas. Several BCHDs were tested, including the Bruckhoff la belle BC D50/70, Radioear B71 headset, Radioear B71 elastic headband, Cochlear Baha SoundArc M, and Cochlear Baha elastic headband, on a PVC artificial head, with data analyzed using ANOVA and LSD post hoc tests. Results: The la belle BC D50/70 spectacles showed comparable contact force to established BCHDs, ensuring adequate sound transmission and comfort. Significant differences were observed between the systems, with the Radioear B71 headset exhibiting the highest forces. The la belle BC D50/70 had similar forces to the Radioear B71 elastic headband. Conclusion: The la belle BC D50/70 universal bone conduction hearing spectacles are a technically equivalent alternative to established BCHDs, maintaining pressure below 5.4 N. Future research should explore the impact of different contact forces on performance and comfort, and the integration of force control in modified spectacles. This study indicates that the la belle BC D50/70 is a viable alternative that meets audiological practice requirements. 展开更多
关键词 Bone Conduction Hearing Devices (BCHD) universal Bone Conduction Hearing Spec-Tacles Non-Implantable Hearing Aids Contact Pressure Optimization
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An In-depth Interpretation of the Universal Declaration of Human Rights With the Common Values of Humanity As the Research Paradigm
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作者 ZHANG Wenxian 《The Journal of Human Rights》 2024年第3期495-508,共14页
Interpreting the Universal Declaration of Human Rights from political,juridical and philosophical perspectives is es-sential for promoting the guiding principles of the Declaration,build-ing consensus on human rights,... Interpreting the Universal Declaration of Human Rights from political,juridical and philosophical perspectives is es-sential for promoting the guiding principles of the Declaration,build-ing consensus on human rights,and advancing human rights practice in the new historical context.To conduct an academic,systematic in-terpretation of the Declaration that conforms to the trends of the times and answers the fundamental questions of the world,it is necessary to find a new research paradigm.The common values of humanity,namely peace,development,equity,justice,democracy and freedom,put forward by Xi Jinping,general secretary of the Communist Party of China(CPC)Central Committee,provide the most explanatory and penetrating scientific paradigm for reaching the issue.This paper an-alyzes and reflects on the views,value foundation and principled(con-tractual)consensus of human rights in the Declaration,and narrates and foresees the far-reaching significance of the three global initia-tives(namely,the Global Development Initiative,the Global Security Initiative,and the Global Civilization Initiative)with the common val-ues of humanity as the soul in advancing the modernization of global human rights governance and building a new form of human rights civilization. 展开更多
关键词 common values of humanity paradigm based on the common values of humanity universal Declaration of Human Rights views of human rights three global initiatives
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Revisiting the Spirit of the UDHR and Discussing Human Rights Development——Summary of Views from the Seminar Commemorating the 75th Anniversary of the Universal Declaration of Human Rights
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作者 刘炫麟 LI Donglin 《The Journal of Human Rights》 2024年第1期231-241,共11页
On December 4,2023,the China Society for Human Rights Studies hosted a seminar in Beijing commemorating the 75^(th) Anniversary of the Universal Declaration of Human Rights.Participants discussed topics such as the si... On December 4,2023,the China Society for Human Rights Studies hosted a seminar in Beijing commemorating the 75^(th) Anniversary of the Universal Declaration of Human Rights.Participants discussed topics such as the significance of the Universal Declaration of Human Rights,China’s theories and practices in respecting and safeguarding human rights,the three global initiatives and global human rights governance,human rights protection in the digital age,and telling Chinese stories of human rights in the new era.The discussions led to a broad consensus and achieved positive results. 展开更多
关键词 The universal Declaration of Human Rights a community with a shared future for mankind the rule of law protection global human rights governance contemporary Chinese perspective on human rights
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Population ageing and the impacts of the universal two-child policy on China’s socio-economy
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作者 Bingwen Zheng 《Economic and Political Studies》 2016年第4期434-453,共20页
The two-child policy was officially proclaimed in the Guideline of the 13th Five-Year Plan and approved in March 2016.This article provides a detailed analysis of the Chinese demographic structure characterised by age... The two-child policy was officially proclaimed in the Guideline of the 13th Five-Year Plan and approved in March 2016.This article provides a detailed analysis of the Chinese demographic structure characterised by ageing with sub-replacement fertility.It argues that the universal two-child policy is timely and necessary for the New Normal economy.The policy has significance in relieving socio-economic pressure and promoting economic growth,for which it is not only a necessary premise but also a sufficient condition.Having reviewed the evolution of the demographic transition theory,this research undertakes a comparative analysis of different stages of demographic transition in different regions across the world.It further investigates the three stages of successful demographic transition in China.The universally adopted two-child policy,as it meets the requirements of demographic transition,is also inevitable for socio-economic development. 展开更多
关键词 Population ageing ageing with sub-replacement fertility one-child policy demographic transition universal two-child policy
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From“selective two-child policy”to universal two-child policy:Will the payment crisis of China’s pension system be solved?
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作者 Zeng Yi Zhang Xinjie Liu Lingchen 《China Finance and Economic Review》 2017年第1期56-76,共21页
With the rapid population aging,the payment crisis of China’s pension insurance fund is increasing yearly.The government adjusts fertility policy to alleviate population aging and improve the solvency of pension insu... With the rapid population aging,the payment crisis of China’s pension insurance fund is increasing yearly.The government adjusts fertility policy to alleviate population aging and improve the solvency of pension insurance fund.On January1,2016,China’s fertility policy was adjusted from“selective two-child policy”to universal two-child policy.This paper establishes actuarial models to analyze how fertility policy adjustment influences the pension insurance fund and concludes as follows:(1)if the“one-child policy”were still employed,the accumulated deficit of pension insurance fund would appear in the year of 2076;(2)if all couples that satisfy the rules of“selective two-child policy”bear the second child,the time of accumulated deficit of pension insurance fund would be postponed by about 9 years;(3)after implementing universal two-child policy,the time of accumulated deficit of pension insurance fund would delay under different situations of fertility intentions,if more than 54% of the qualified couples bear a second child,the accumulated deficit of pension insurance fund would not appear before 2090.The above conclusions have passed the sensitivity tests.Therefore,“two-child policy”can alleviate the payment pressure of pension insurance fund.If the government wants to solve the payment crisis of pension insurance fund,fertility intentions should be improved. 展开更多
关键词 universal two-child policy pension insurance fund payment crisis policy simulation
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The Impacts of the Universal Two-Child Policy on China's Population
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作者 Zhenwu ZHAI Long LI Jiaju CHEN 《China Population and Development Studies》 2017年第1期1-18,共18页
The universal two-child policy,implemented in October,2015,is considered to be the most significant adjustment in the history of China's family planning program.Using data from the 2014 national population samplin... The universal two-child policy,implemented in October,2015,is considered to be the most significant adjustment in the history of China's family planning program.Using data from the 2014 national population sampling survey,this paper employs a population group-component calculation and projection method to compute the number of target population in 2016 and then to estimate the number of extra births that are likely to result from implementation of the universal two-child policy.The results show that the total number of extra births is estimated to be approximately 17.2 million in the years 2017-2021,with the number of extra births per year ranging from approximately 1.6 to 4.7 million.This will lead to a dramatic shift in China's TFR from an estimated 1.6 in 2016 to one approaching the replacement level,and then dropping to a projected 1.7.With the universal two-child policy in place,China's total population will grow to about 1.45 billion around 2028 and then gradually begin shrioking.The labor force will become larger under the universal two-child policy than it would if the stricter birth control policy were maintained,with an estimated 50 million additional people aged 15-59 in 2050.With implementation of China's new fertility policy,an estimated 34%of the population will be over 60 years of age in 2050,almost three percentage points lower than the level if the former fertility policy were continued. 展开更多
关键词 universal two-child Policy Target Population Extra Births.Population Trends.Population Group-component Calculation and Projection Method
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从同文馆到北京大学:近代中国“Peking University”概念考论
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作者 宋雪 《教育学报》 北大核心 2024年第4期195-207,共13页
从晚清到民国,“Peking University”的指称对象先后包括京师同文馆、汇文书院、京师大学堂、私立燕京大学和国立北京大学五所驻京高等教育机构,其中既有国立最高学府,也有私立教会学校。虽然部分属于非正式名称,但仍具有广泛社会影响... 从晚清到民国,“Peking University”的指称对象先后包括京师同文馆、汇文书院、京师大学堂、私立燕京大学和国立北京大学五所驻京高等教育机构,其中既有国立最高学府,也有私立教会学校。虽然部分属于非正式名称,但仍具有广泛社会影响。语言概念的重叠带来话语表达中的歧义,同时也投射出多元复杂的历史图景。依据档案、报刊、辞书、回忆录等材料,返回历史现场,梳理近代中国“Peking University”概念的生成和流变,从中考察新式教育的引入、中西观念的互动及文化空间的形成,有助于探求译名背后的知识建构、教育转型与社会变迁。 展开更多
关键词 Peking university 同文馆 京师大学堂 北京大学 燕京大学 概念史 教育转型
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角膜横径和晶状体厚度在Barrett UniversalⅡ人工晶状体计算公式中的应用价值
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作者 张彧 刘杰为 +1 位作者 刘文洁 柴飞燕 《眼科学报》 CAS 2023年第12期822-836,共15页
目的:探讨运用Barrett UniversalⅡ公式(BUⅡ公式)计算人工晶状体(intraocular lens,IOL)屈光力时,可选参数角膜横径,又称白到白(white-to-white,WTW)与晶状体厚度(lens thickness,LT)的实际应用价值。方法:采用单中心、前瞻性临床研究... 目的:探讨运用Barrett UniversalⅡ公式(BUⅡ公式)计算人工晶状体(intraocular lens,IOL)屈光力时,可选参数角膜横径,又称白到白(white-to-white,WTW)与晶状体厚度(lens thickness,LT)的实际应用价值。方法:采用单中心、前瞻性临床研究,连续纳入同一术者顺利进行白内障超声乳化吸除术联合MX60(IOL植入术患眼279眼,术前使用OA-2000非接触式光学生物测量仪测量眼部数据并计算IOL植入度数,代入BUⅡ公式保留或去掉可选参数WTW、LT计算预测结果,进一步根据患者眼轴长度(axial length,AL)分亚组分析。主要结局指标:随访患者至术后1个月以上,比较使用和未使用WTW和LT两个参数、BUⅡ公式预测误差(prediction error,PE)、绝对预测误差(absolute error,AE)、AE小于0.5 D所占比例。结果:总体1上,忽略WTW+LT,PE为-0.05 D(-0.26,0.18)(P=0.011),其他参数组合的PE与0比较差异无统计学意义(P>0.05)。各参数组合的AE比较差异无统计学意义(0.22~0.23 D,P=0.404)。同时忽略WTW+LT时AE出现最大值(+1.5 D)。应用WTW+LT、忽略WTW+LT、忽略WTW和忽略LT时纳入患者AE≤0.50 D的比例分别为80.65%、79.57%、80.65%和81.36%。在各眼轴亚组中,忽略LT时,AE≤0.50 D的百分比在短眼轴亚组(80.00%vs.66.67%~73.33%)与长眼轴亚组(77.78%vs.73.33%~75.56%)中较高。在中等眼轴亚组中,AE≤0.50 D百分比代入全部参数时略高(83.11%vs.80.82%~82.19%),忽略WTW+LT计算时稍低(80.82%)。结论:使用BUⅡ计算IOL屈光力时,可选参数WTW和LT无论是否代入公式中,皆可得到相近的平均预测水平;但是,同时忽略WTW和LT可能出现较大预测误差。对于22mm≤AL<26mm眼,推荐代入全部参数计算;当AL≤22mm或AL≥26mm,仅输入WTW的计算方法累积精确度更高,可优先采用。 展开更多
关键词 人工晶状体计算公式 Barrett universalⅡ公式 白内障手术 准确性 眼轴长度
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Facing challenges with hope:universal immune cells for hematologic malignancies 被引量:3
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作者 Yuqing Wang Ruihao Huang +3 位作者 Zheng Wang Jingkang Xiong Xiaoqi Wang Xi Zhang 《Cancer Biology & Medicine》 SCIE CAS CSCD 2023年第4期229-247,共19页
Many patients have achieved a favorable overall survival rate since allogenic hematopoietic stem cell transplantation(allo-HSCT)has been widely implemented to treat hematologic malignancies.However,graft-versus-host d... Many patients have achieved a favorable overall survival rate since allogenic hematopoietic stem cell transplantation(allo-HSCT)has been widely implemented to treat hematologic malignancies.However,graft-versus-host disease(GVHD)and complications of immunosuppressive drugs after allo-HSCT are the main causes of non-relapse mortality and a poor quality of life.In addition,GVHD and infusion-induced toxicity still occur with donor lymphocyte infusions(DLIs)and chimeric antigen receptor(CAR)T-cell therapy.Because of the special immune tolerance characteristics and anti-tumor ability of universal immune cells,universal immune cell therapy may strongly reduce GVHD,while simultaneously reducing tumor burden.Nevertheless,widespread application of universal immune cell therapy is mainly restricted by poor expansion and persistence efficacy.Many strategies have been applied to improve universal immune cell proliferation and persistence efficacy,including the use of universal cell lines,signaling regulation and CAR technology.In this review we have summarized current advances in universal immune cell therapy for hematologic malignancies with a discussion of future perspectives. 展开更多
关键词 universal immune cells graft-versus-host disease immune tolerance chimeric antigen receptor
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