Atrial fibrillation(AF) and heart failure(HF) are complex clinical entities that occur concomitantly in a significant population of patients, and their prevalence is rising in epidemic proportions. Traditionally, both...Atrial fibrillation(AF) and heart failure(HF) are complex clinical entities that occur concomitantly in a significant population of patients, and their prevalence is rising in epidemic proportions. Traditionally, both rate and rhythm control strategies have been regarded as equivalent in the management of dysrhythmia in this AF-HF cohort with escalation of treatment largely guided by symptoms. Both disorders are involved in an elaborate pathophysiological interplay with shared cardiovascular risk factors that contribute to the development and sustenance of both AF and HF. Recent studies and continued development of evidence to support catheter ablation for AF has brought into question the traditional belief in equivalence between rate and rhythm control. Indeed, recent trials, in particular the CASTLE-AF(Catheter Ablation versus Standard Conventional Therapy in Patients with Left Ventricular Dysfunction and Atrial Fibrillation) study, suggest that catheter ablation for AF improves survival and rates of hospitalisation in patients with concomitant HF and AF, threatening a paradigm shift in the management of this patient cohort. The evident mortality benefit from clinical trials suggests that catheter ablation for AF should be considered as a therapeutic intervention in all suitable patients with the AF-HF syndrome as these patients may derive the greatest benefit from restoration of sinus rhythm. Further research is needed to refine the evidence base, especially to determine which subgroup of HF patients benefit most from catheter ablation and what is the optimal timing.展开更多
1. Introduction Remotely operated vchicles (ROV) are advanced technical underwater operating equip-ment. They are whidely used in underwater engineering, underwater rescue and sea oil activities.General ROVs can work ...1. Introduction Remotely operated vchicles (ROV) are advanced technical underwater operating equip-ment. They are whidely used in underwater engineering, underwater rescue and sea oil activities.General ROVs can work in deep water. But the horizontal working distance is limited. Atmaximal working depth they can usually move around the mother ship inside a circle with a di-展开更多
Guan Qiqian, a 42-year-old journalist in Yongqing of southeast China＇s Fujian Province, never expected his search for medical treatment of his psoriasis in 2000 ended up in hepatitis and uremia.
The six-party talks aimed at checking North Korea’s pursuit of a nuclear arsenal should be resumed immediately-without preconditions Last month, in the aftermath of bilateral talks between the United States and North...The six-party talks aimed at checking North Korea’s pursuit of a nuclear arsenal should be resumed immediately-without preconditions Last month, in the aftermath of bilateral talks between the United States and North Korea over its nuclear weapons capacity, Pyongyang of-展开更多
Beijing is working to resolve its longtime transportation problems before the 2008 Olympics One traffic jam after another, annoying horns, endless lines of cars,impatient sighs from passengers on an overcrowded bus, t...Beijing is working to resolve its longtime transportation problems before the 2008 Olympics One traffic jam after another, annoying horns, endless lines of cars,impatient sighs from passengers on an overcrowded bus, the youstomped-on-my-toe quarreling in the subway train, all have led to the unsurprising result that Beijing scored at the tail end of a survey of 287 cities in the category of transport satisfaction in China’s 2006 Report on the Quality of Urban Life.展开更多
文摘Atrial fibrillation(AF) and heart failure(HF) are complex clinical entities that occur concomitantly in a significant population of patients, and their prevalence is rising in epidemic proportions. Traditionally, both rate and rhythm control strategies have been regarded as equivalent in the management of dysrhythmia in this AF-HF cohort with escalation of treatment largely guided by symptoms. Both disorders are involved in an elaborate pathophysiological interplay with shared cardiovascular risk factors that contribute to the development and sustenance of both AF and HF. Recent studies and continued development of evidence to support catheter ablation for AF has brought into question the traditional belief in equivalence between rate and rhythm control. Indeed, recent trials, in particular the CASTLE-AF(Catheter Ablation versus Standard Conventional Therapy in Patients with Left Ventricular Dysfunction and Atrial Fibrillation) study, suggest that catheter ablation for AF improves survival and rates of hospitalisation in patients with concomitant HF and AF, threatening a paradigm shift in the management of this patient cohort. The evident mortality benefit from clinical trials suggests that catheter ablation for AF should be considered as a therapeutic intervention in all suitable patients with the AF-HF syndrome as these patients may derive the greatest benefit from restoration of sinus rhythm. Further research is needed to refine the evidence base, especially to determine which subgroup of HF patients benefit most from catheter ablation and what is the optimal timing.
文摘1. Introduction Remotely operated vchicles (ROV) are advanced technical underwater operating equip-ment. They are whidely used in underwater engineering, underwater rescue and sea oil activities.General ROVs can work in deep water. But the horizontal working distance is limited. Atmaximal working depth they can usually move around the mother ship inside a circle with a di-
文摘Guan Qiqian, a 42-year-old journalist in Yongqing of southeast China＇s Fujian Province, never expected his search for medical treatment of his psoriasis in 2000 ended up in hepatitis and uremia.
文摘The six-party talks aimed at checking North Korea’s pursuit of a nuclear arsenal should be resumed immediately-without preconditions Last month, in the aftermath of bilateral talks between the United States and North Korea over its nuclear weapons capacity, Pyongyang of-
文摘Beijing is working to resolve its longtime transportation problems before the 2008 Olympics One traffic jam after another, annoying horns, endless lines of cars,impatient sighs from passengers on an overcrowded bus, the youstomped-on-my-toe quarreling in the subway train, all have led to the unsurprising result that Beijing scored at the tail end of a survey of 287 cities in the category of transport satisfaction in China’s 2006 Report on the Quality of Urban Life.
