Rattle structure is a topic of great interest in design and application of nano- materials due to the unique core@void@shell architecture and the integration of functions. Herein, we developed a novel "ship-in-a-bot...Rattle structure is a topic of great interest in design and application of nano- materials due to the unique core@void@shell architecture and the integration of functions. Herein, we developed a novel "ship-in-a-bottle" method to fabricate upconverting (UC) luminescent nanorattles by incorporating lanthanide-doped fluorides into hollow mesoporous silica. The size of nanorattles and the filling amount of fluorides can be well controlled. In addition, the modification of silica shell (with phenylene and amine groups) and the variation of efficient UC fluorides (NaYF4:Yb, Er, NaLuF4:Yb, Er, NaGdF4:Yb, Er and LiYF4:Yb, Er) were readily achieved. The resulting nanorattles exhibited a high capacity and pH-dependent release of the anti-cancer drug doxorubicin (DOX). Furthermore, we employed these nanorattles in proof-of-concept UC-monitoring drug release by utilizing the energy transfer process from UC fluorides to DOX, thus revealing the great potential of the nanorattles as efficient cancer theranostic agent.展开更多
Achieving large luminescence dissymmetry factors(pium)is challenging in the research field of circularly polarized luminescence(CPL).While various approaches have been developed to construct organic systems with CPL a...Achieving large luminescence dissymmetry factors(pium)is challenging in the research field of circularly polarized luminescence(CPL).While various approaches have been developed to construct organic systems with CPL activity,there is still a lack of effective methods for fabricating CPL active inorganic materials.Herein,we propose an approach for endowing upconversion nanoparticles(UCNPs)and perovskite nanocrystal(PKNC)hybrid nanomaterials with upconverted circularly polarized luminescence(UC-CPL)activity.Chiral cesium lead bromides(CsPbBr_(3))PKNCs were synthesized by a chiral-ligand-assistant method.Meanwhile,UCNP could be embedded into the chiral PKNC,enabling a photon upconvesion feature to the PKNC.The embedded UCNPs in PKNCs were confirmed by electron tomography.Consequently,various CPL activities,including prompt CPL,UC-CPL,and energy transfer enhanced circularly polarized luminescence(ET-CPL),were realized.The chiral perovskite nanocrystals could reabsorb the chiral energy generated from UCNPs,showing energy transfer enhanced CPL activity with four times magnification of the circular polarization.These findings provide a meaningful strategy for designing chiral photon upconversion inorganic nanomaterials with highly efficient UC-CPL activity.展开更多
基金This work is supported by the National Basic Research Program of China (No. 2014CB845605), Special Project of National Major Scientific Equipment Development of China (No. 2012YQ120060), the National Natural Science Foundation of China (Nos. 21201163, 21401196, U1305244, and 21325104), the CAS/SAFEA International Partnership Program for Creative Research Teams, and Strategic Priority Research Program of the CAS (No. XDA09030307).
文摘Rattle structure is a topic of great interest in design and application of nano- materials due to the unique core@void@shell architecture and the integration of functions. Herein, we developed a novel "ship-in-a-bottle" method to fabricate upconverting (UC) luminescent nanorattles by incorporating lanthanide-doped fluorides into hollow mesoporous silica. The size of nanorattles and the filling amount of fluorides can be well controlled. In addition, the modification of silica shell (with phenylene and amine groups) and the variation of efficient UC fluorides (NaYF4:Yb, Er, NaLuF4:Yb, Er, NaGdF4:Yb, Er and LiYF4:Yb, Er) were readily achieved. The resulting nanorattles exhibited a high capacity and pH-dependent release of the anti-cancer drug doxorubicin (DOX). Furthermore, we employed these nanorattles in proof-of-concept UC-monitoring drug release by utilizing the energy transfer process from UC fluorides to DOX, thus revealing the great potential of the nanorattles as efficient cancer theranostic agent.
基金supported by the Strategic Priority Research Program of Chinese Academy of Sciences(No.XDB36000000)the National Natural Science Foundation of China(Nos.21802027,21908161,51673050,and 91856115)+1 种基金the Ministry of Science and Technology of the Peoples Republic of China(No.2017YFA0206600,and 2016YFA0203400)Beijing Natural Science Foundation(No.2212023)。
文摘Achieving large luminescence dissymmetry factors(pium)is challenging in the research field of circularly polarized luminescence(CPL).While various approaches have been developed to construct organic systems with CPL activity,there is still a lack of effective methods for fabricating CPL active inorganic materials.Herein,we propose an approach for endowing upconversion nanoparticles(UCNPs)and perovskite nanocrystal(PKNC)hybrid nanomaterials with upconverted circularly polarized luminescence(UC-CPL)activity.Chiral cesium lead bromides(CsPbBr_(3))PKNCs were synthesized by a chiral-ligand-assistant method.Meanwhile,UCNP could be embedded into the chiral PKNC,enabling a photon upconvesion feature to the PKNC.The embedded UCNPs in PKNCs were confirmed by electron tomography.Consequently,various CPL activities,including prompt CPL,UC-CPL,and energy transfer enhanced circularly polarized luminescence(ET-CPL),were realized.The chiral perovskite nanocrystals could reabsorb the chiral energy generated from UCNPs,showing energy transfer enhanced CPL activity with four times magnification of the circular polarization.These findings provide a meaningful strategy for designing chiral photon upconversion inorganic nanomaterials with highly efficient UC-CPL activity.