Purpose:This study investigated the effects of obesity on breast size,thoracic spine structure and function,upper torso musculoskeletal pain and physical activity participation in women living independently in the com...Purpose:This study investigated the effects of obesity on breast size,thoracic spine structure and function,upper torso musculoskeletal pain and physical activity participation in women living independently in the community.Methods:A total of 378 women were divided into 3 groups(Not Overweight:body mass index(BMI)=22.5±0.2 kg/m^2(mean±SE);Overweight:BMI=27.4±0.3 kg/m^2;Obese:BMI=35.4±0.3 kg/m^2).Outcome variables of breast volume(mL),thoracic flexion torque(N·m),thoracic kyphosis(degrees),upper torso musculoskeletal pain(score) and time spent in physical activity(min) were calculated and compared among the 3 groups,adjusting for between-group differences in age.Results:There was a significant main effect of BMI on all outcome variables.Participants classified as Obese displayed significantly larger breasts,had greater thoracic flexion torques and reported less time participating in physical activity relative to the participants who were classified as Not Overweight and Overweight.Participants in the Obese group also displayed significantly more thoracic kyphosis and reported significantly more upper torso musculoskeletal pain compared to their counterparts who were classified as Not Overweight.Conclusion:This study is the first to demonstrate that increased obesity levels were associated with compromised kyphosis and loading of the thoracic spine,as well as increased symptoms of upper torso musculoskeletal pain and reduced time spent in physical activity in women living in the community.We recommend further research to determine whether evidence-based interventions designed to reduce the flexion torque generated on the thoracic spine can improve these symptoms of upper torso musculoskeletal pain and the ability of women with obesity to participate in physical activity.展开更多
This paper presents two kinematic failure mechanisms of threc-dimensional rectangular footing resting on homogeneous undrained clay foundation under uniaxial vertical loading and uniaxial moment loading. The failure m...This paper presents two kinematic failure mechanisms of threc-dimensional rectangular footing resting on homogeneous undrained clay foundation under uniaxial vertical loading and uniaxial moment loading. The failure mechanism under vertical loading comprises a plane strain Prandti-type mechanism over the central part of the longer side, and the size of the mechanism gradually reduces at the ends of the longer side and over the shorter side as the corner of rectangular footing is being approached where the direction of soil motion remains normal to each corresponding side respectively. The failure mechanism under moment loading comprises a plane strain scoop sliding mechanism over the central part of the longer side, and the radius of scoop sliding mechanism increases linearly at the ends of the longer side. On the basis of the kinematic failure mechanisms mentioned above, the vertical ultimate bearing capacity and the ultimate bearing capacity against moment or moment ultimate bearing capacity are obtained by use of upper bound limit analysis theory. At the same time, numerical analysis results, Skempton＇ s results and Salgado et al. ＇s results are compared with this upper bound solution. It shows that the presented failure mechanisms and plastic limit analysis predictions are validated. In order to investigate the behaviors of undrained clay foundation beneath the rectangular footing subjected to the combined loadings, numerical analysis is adopted by virtue of the general-purpose FEM software ABAQUS, where the clay is assumed to obey the Mohr-Coulomb yielding criterion. The failure envelope and the ultimate bearing capacity are achieved by the numerical analysis results with the varying aspect ratios from length L to breadth B of the rectangular footing. The failure mechanisms of rectangular footing which are subjected to the combined vertical loading V and horizontal loading H （Vertical loading V and moment loading M, and horizontal loading H and moment loading M respectively are observed in the finite element analysis. ） is explained by use of the upper bound plasticity limit analysis theory. Finally, the reason of eccentricity of failure envelope in H-M loading space is given in this study, which can not be explained by use of the traditional ＇ swipe test＇.展开更多
An inflatable cuff wrapped around the upper arm is widely used in noninvasive blood pressure measurement.However, the mechanical interaction between cuff and arm tissues, a factor that potentially affects the accuracy...An inflatable cuff wrapped around the upper arm is widely used in noninvasive blood pressure measurement.However, the mechanical interaction between cuff and arm tissues, a factor that potentially affects the accuracy of noninvasive blood pressure measurement, remains rarely addressed. In the present study, finite element（FE） models were constructed to quantify intra-arm stresses generated by cuff compression, aiming to provide some theoretical evidence for identifying factors of importance for blood pressure measurement or explaining clinical observations. Obtained results showed that the simulated tissue stresses were highly sensitive to the distribution of cuff pressure on the arm surface and the contact condition between muscle and bone. In contrast, the magnitude of cuff pressure and small variations in elastic properties of arm soft tissues had little influence on the efficiency of pressure transmission in arm tissues. In particular, it was found that a thickened subcutaneous fat layer in obese subjects significantly reduced the effective pressure transmitted to the brachial artery, which may explain why blood pressure overestimation occurs more frequently in obese subjects in noninvasive blood pressure measurement.展开更多
由于受人类活动及气候变化影响,黄河上游干流水沙特征发生显著变化。为探究黄河上游水沙变化情况,基于黄河上游5个水文站19642019年水沙、遥感影像等数据,利用Mann-Kendall检验法、滑动t检验法、累积距平曲线和双累积曲线等突变检验方...由于受人类活动及气候变化影响,黄河上游干流水沙特征发生显著变化。为探究黄河上游水沙变化情况,基于黄河上游5个水文站19642019年水沙、遥感影像等数据,利用Mann-Kendall检验法、滑动t检验法、累积距平曲线和双累积曲线等突变检验方法和小波分析法,对黄河上游水沙变化特征进行研究。利用水沙关系曲线及线性回归法等方法估算人类活动和气候对水沙变化的贡献率,并着重讨论梯级水库建设及土地利用变化对水沙的影响。结果表明:1)黄河上游玛曲-小川段流域内降雨量和径流量变化幅度不明显,贵德站、循化站、小川站19862019年年均输沙量分别减至19641985年的9.8%、24.6%、38.8%,输沙量大大减少。黄河上游玛曲-小川段径流量突变多在1986年,输沙量突变多在1969、1986、2004年,径流量存在8、16、22 a周期,输沙量存在4~8、18~21、27 a周期。2)1969年后,河流输沙能力增强,水沙关系显著改变。在不同时段内,人类活动对径流量变化在19872019年贡献率为66.3%,对输沙量变化在19701986、19872004、20052019年的贡献率为72.96%、70.73%、69.7%。人类活动对黄河上游干流水沙影响占据主导因素。3)刘家峡水库淤积最为严重,单库运行期水库淤积量为2.39亿t,排沙比变化范围为1.39%~10.7%。梯级水库联调使得径流量在19642004年间减少47.8%,19642019年间梯级水库减沙94.8%,梯级水库对输沙量影响远大于对径流量的影响。4)19802020年间,草地面积增加了1880.03 km 2,增幅3.1%,有利于减少输沙量,草地拦沙效益大于截流效益。展开更多
基金support of the Australian Government Research Training Program Scholarshipthe Sports Medicine Australia Research Foundation,which providcd partial funding towards this study。
文摘Purpose:This study investigated the effects of obesity on breast size,thoracic spine structure and function,upper torso musculoskeletal pain and physical activity participation in women living independently in the community.Methods:A total of 378 women were divided into 3 groups(Not Overweight:body mass index(BMI)=22.5±0.2 kg/m^2(mean±SE);Overweight:BMI=27.4±0.3 kg/m^2;Obese:BMI=35.4±0.3 kg/m^2).Outcome variables of breast volume(mL),thoracic flexion torque(N·m),thoracic kyphosis(degrees),upper torso musculoskeletal pain(score) and time spent in physical activity(min) were calculated and compared among the 3 groups,adjusting for between-group differences in age.Results:There was a significant main effect of BMI on all outcome variables.Participants classified as Obese displayed significantly larger breasts,had greater thoracic flexion torques and reported less time participating in physical activity relative to the participants who were classified as Not Overweight and Overweight.Participants in the Obese group also displayed significantly more thoracic kyphosis and reported significantly more upper torso musculoskeletal pain compared to their counterparts who were classified as Not Overweight.Conclusion:This study is the first to demonstrate that increased obesity levels were associated with compromised kyphosis and loading of the thoracic spine,as well as increased symptoms of upper torso musculoskeletal pain and reduced time spent in physical activity in women living in the community.We recommend further research to determine whether evidence-based interventions designed to reduce the flexion torque generated on the thoracic spine can improve these symptoms of upper torso musculoskeletal pain and the ability of women with obesity to participate in physical activity.
基金This project is financially supported by the National Natural Science Foundation of China(Grant Nos.50639010,50579006 and 50179006)
文摘This paper presents two kinematic failure mechanisms of threc-dimensional rectangular footing resting on homogeneous undrained clay foundation under uniaxial vertical loading and uniaxial moment loading. The failure mechanism under vertical loading comprises a plane strain Prandti-type mechanism over the central part of the longer side, and the size of the mechanism gradually reduces at the ends of the longer side and over the shorter side as the corner of rectangular footing is being approached where the direction of soil motion remains normal to each corresponding side respectively. The failure mechanism under moment loading comprises a plane strain scoop sliding mechanism over the central part of the longer side, and the radius of scoop sliding mechanism increases linearly at the ends of the longer side. On the basis of the kinematic failure mechanisms mentioned above, the vertical ultimate bearing capacity and the ultimate bearing capacity against moment or moment ultimate bearing capacity are obtained by use of upper bound limit analysis theory. At the same time, numerical analysis results, Skempton＇ s results and Salgado et al. ＇s results are compared with this upper bound solution. It shows that the presented failure mechanisms and plastic limit analysis predictions are validated. In order to investigate the behaviors of undrained clay foundation beneath the rectangular footing subjected to the combined loadings, numerical analysis is adopted by virtue of the general-purpose FEM software ABAQUS, where the clay is assumed to obey the Mohr-Coulomb yielding criterion. The failure envelope and the ultimate bearing capacity are achieved by the numerical analysis results with the varying aspect ratios from length L to breadth B of the rectangular footing. The failure mechanisms of rectangular footing which are subjected to the combined vertical loading V and horizontal loading H （Vertical loading V and moment loading M, and horizontal loading H and moment loading M respectively are observed in the finite element analysis. ） is explained by use of the upper bound plasticity limit analysis theory. Finally, the reason of eccentricity of failure envelope in H-M loading space is given in this study, which can not be explained by use of the traditional ＇ swipe test＇.
基金supported in part by the National Natural Science Foundation of China (Grant 81370438)the SJTU Medical-Engineering Cross-cutting Research Project (Grant YG2015MS53)supported by the Hui-Chun Chin and Tsung-Dao Lee Chinese Undergraduate Research Program Endowment
文摘An inflatable cuff wrapped around the upper arm is widely used in noninvasive blood pressure measurement.However, the mechanical interaction between cuff and arm tissues, a factor that potentially affects the accuracy of noninvasive blood pressure measurement, remains rarely addressed. In the present study, finite element（FE） models were constructed to quantify intra-arm stresses generated by cuff compression, aiming to provide some theoretical evidence for identifying factors of importance for blood pressure measurement or explaining clinical observations. Obtained results showed that the simulated tissue stresses were highly sensitive to the distribution of cuff pressure on the arm surface and the contact condition between muscle and bone. In contrast, the magnitude of cuff pressure and small variations in elastic properties of arm soft tissues had little influence on the efficiency of pressure transmission in arm tissues. In particular, it was found that a thickened subcutaneous fat layer in obese subjects significantly reduced the effective pressure transmitted to the brachial artery, which may explain why blood pressure overestimation occurs more frequently in obese subjects in noninvasive blood pressure measurement.
文摘由于受人类活动及气候变化影响,黄河上游干流水沙特征发生显著变化。为探究黄河上游水沙变化情况,基于黄河上游5个水文站19642019年水沙、遥感影像等数据,利用Mann-Kendall检验法、滑动t检验法、累积距平曲线和双累积曲线等突变检验方法和小波分析法,对黄河上游水沙变化特征进行研究。利用水沙关系曲线及线性回归法等方法估算人类活动和气候对水沙变化的贡献率,并着重讨论梯级水库建设及土地利用变化对水沙的影响。结果表明:1)黄河上游玛曲-小川段流域内降雨量和径流量变化幅度不明显,贵德站、循化站、小川站19862019年年均输沙量分别减至19641985年的9.8%、24.6%、38.8%,输沙量大大减少。黄河上游玛曲-小川段径流量突变多在1986年,输沙量突变多在1969、1986、2004年,径流量存在8、16、22 a周期,输沙量存在4~8、18~21、27 a周期。2)1969年后,河流输沙能力增强,水沙关系显著改变。在不同时段内,人类活动对径流量变化在19872019年贡献率为66.3%,对输沙量变化在19701986、19872004、20052019年的贡献率为72.96%、70.73%、69.7%。人类活动对黄河上游干流水沙影响占据主导因素。3)刘家峡水库淤积最为严重,单库运行期水库淤积量为2.39亿t,排沙比变化范围为1.39%~10.7%。梯级水库联调使得径流量在19642004年间减少47.8%,19642019年间梯级水库减沙94.8%,梯级水库对输沙量影响远大于对径流量的影响。4)19802020年间,草地面积增加了1880.03 km 2,增幅3.1%,有利于减少输沙量,草地拦沙效益大于截流效益。
