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A dynamic and resource sharing virtual network mapping algorithm
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作者 Xiancui Xiao Xiangwei Zheng +2 位作者 Ji Bian Cun Ji Xinchun Cui 《Digital Communications and Networks》 SCIE CSCD 2023年第5期1101-1112,共12页
Network virtualization can effectively establish dedicated virtual networks to implement various network functions.However,the existing research works have some shortcomings,for example,although computing resource pro... Network virtualization can effectively establish dedicated virtual networks to implement various network functions.However,the existing research works have some shortcomings,for example,although computing resource properties of individual nodes are considered,node storage properties and the network topology properties are usually ignored in Virtual Network(VN)modelling,which leads to the inaccurate measurement of node availability and priority.In addition,most static virtual network mapping methods allocate fixed resources to users during the entire life cycle,and the users’actual resource requirements vary with the workload,which results in resource allocation redundancy.Based on the above analysis,in this paper,we propose a dynamic resource sharing virtual network mapping algorithm named NMA-PRS-VNE,first,we construct a new,more realistic network framework in which the properties of nodes include computing resources,storage resources and topology properties.In the node mapping process,three properties of the node are used to measure its mapping ability.Second,we consider the resources of adjacent nodes and links instead of the traditional method of measuring the availability and priority of nodes by considering only the resource properties,so as to more accurately select the physical mapping nodes that meet the constraints and conditions and improve the success rate of subsequent link mapping.Finally,we divide the resource requirements of Virtual Network Requests(VNRs)into basic subrequirements and variable sub-variable requirements to complete dynamic resource allocation.The former represents monopolizing resource requirements by the VNRs,while the latter represents shared resources by many VNRs with the probability of occupying resources,where we keep a balance between resource sharing and collision among users by calculating the collision probability.Simulation results show that the proposed NMAPRS-VNE can increase the average acceptance rate and network revenue by 15%and 38%,and reduce the network cost and link pressure by 25%and 17%. 展开更多
关键词 Network virtualization vnrs Network frameworks Dynamic resource allocation Resource sharing
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阿司匹林联合长春瑞滨对人乳腺癌细胞MCF-7的作用机制研究 被引量:4
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作者 边静 张彭辉 李佳佳 《西北药学杂志》 CAS 2021年第1期52-56,共5页
目的探究阿司匹林联合长春瑞滨(VNR)对人乳腺癌细胞MCF-7的作用机制。方法体外培养人乳腺癌细胞MCF-7,分为空白对照组、VNR组以及阿司匹林+VNR低、高剂量组。使用MTT法检测MCF-7细胞的增殖情况,使用流式细胞仪检测MCF-7细胞的凋亡率及... 目的探究阿司匹林联合长春瑞滨(VNR)对人乳腺癌细胞MCF-7的作用机制。方法体外培养人乳腺癌细胞MCF-7,分为空白对照组、VNR组以及阿司匹林+VNR低、高剂量组。使用MTT法检测MCF-7细胞的增殖情况,使用流式细胞仪检测MCF-7细胞的凋亡率及周期变化,使用Western Blot和RT-PCR定性、半定量检测B细胞淋巴瘤/白血病-2(Bcl-2)、Bcl相关X蛋白(Bax)、半胱氨酸蛋白酶3(Caspase-3)、半胱氨酸蛋白酶9(Caspase-9)、磷酸化丝氨酸苏氨酸激酶(P-Akt)和丝氨酸苏氨酸激酶(Akt)的蛋白表达量。结果MTT观察结果显示,与空白对照组比较,VNR组和阿司匹林+VNR低剂量组MCF-7细胞抑制率显著升高(P<0.01);与阿司匹林+VNR低剂量组比较,阿司匹林+VNR高剂量组MCF-7细胞抑制率有一定程度升高(P<0.05)。流式细胞仪检测结果显示,与空白对照组比较,VNR组和阿司匹林+VNR低、高剂量组细胞凋亡率均显著增加,S期细胞数量比例显著增加(P<0.01)。与空白对照组比较,VNR组Bax、Caspase-3和Caspase-9蛋白表达显著升高(P<0.01),Bcl-2和P-Akt蛋白表达显著降低(P<0.01);与VNR组比较,阿司匹林+VNR低、高剂量组Bax、Caspase-3和Caspase-9蛋白表达显著升高(P<0.01),Bcl-2和P-Akt蛋白表达显著降低(P<0.01);与阿司匹林+VNR低剂量组比较,阿司匹林+VNR高剂量组Bax、Caspase-3和Caspase-9蛋白表达显著升高(P<0.01),Bcl-2和P-Akt蛋白表达显著降低(P<0.01)。结论阿司匹林联合VNR可通过下调抑凋亡蛋白Bcl-2,上调促凋亡蛋白Bax、凋亡调控因子Caspase-3和Caspase-9蛋白表达,抑制磷脂酰肌醇3-激酶/丝氨酸苏氨酸激酶(PI3K/Akt)信号通路达到抑制乳腺癌细胞增殖、促进乳腺癌细胞凋亡的效果。 展开更多
关键词 MCF-7 阿司匹林 长春瑞滨 人乳腺癌细胞 细胞凋亡
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An Exact Virtual Network Embedding Algorithm Based on Integer Linear Programming for Virtual Network Request with Location Constraint 被引量:3
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作者 Zeheng Yang Yongan Guo 《China Communications》 SCIE CSCD 2016年第8期177-183,共7页
Network virtualization is known as a promising technology to tackle the ossification of current Internet and will play an important role in the future network area. Virtual network embedding(VNE) is a key issue in net... Network virtualization is known as a promising technology to tackle the ossification of current Internet and will play an important role in the future network area. Virtual network embedding(VNE) is a key issue in network virtualization. VNE is NP-hard and former VNE algorithms are mostly heuristic in the literature.VNE exact algorithms have been developed in recent years. However, the constraints of exact VNE are only node capacity and link bandwidth.Based on these, this paper presents an exact VNE algorithm, ILP-LC, which is based on Integer Linear Programming(ILP), for embedding virtual network request with location constraints. This novel algorithm is aiming at mapping virtual network request(VNR) successfully as many as possible and consuming less substrate resources.The topology of each VNR is randomly generated by Waxman model. Simulation results show that the proposed ILP-LC algorithm outperforms the typical heuristic algorithms in terms of the VNR acceptance ratio, at least 15%. 展开更多
关键词 network virtualization virtual network embedding exact VNE algorithm integer linear Programming location constraint vnr acceptance ratio
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