BACKGROUND Subchorionic hematoma(SCH)is a common complication in early pregnancy characterized by the accumulation of blood between the uterine wall and the chorionic membrane.SCH can lead to adverse pregnancy outcome...BACKGROUND Subchorionic hematoma(SCH)is a common complication in early pregnancy characterized by the accumulation of blood between the uterine wall and the chorionic membrane.SCH can lead to adverse pregnancy outcomes such as miscarriage,preterm birth,and other complications.Early detection and accurate assessment of SCH are crucial for appropriate management and improved pregnancy outcomes.AIM To evaluate the diagnostic efficacy of virtual organ computer-assisted analysis(VOCAL)in measuring the volume ratio of SCH to gestational sac(GS)combined with serum progesterone on early pregnancy outcomes in patients with SCH.METHODS A total of 153 patients with SCH in their first-trimester pregnancies between 6 and 11 wk were enrolled.All patients were followed up until a gestational age of 20 wk.The parameters of transvaginal two-dimensional ultrasound,including the circumference of SCH(Cs),surface area of SCH(Ss),circumference of GS(Cg),and surface area of GS(Sg),and the parameters of VOCAL with transvaginal three-dimensional ultrasound,including the three-dimensional volume of SCH(3DVs)and GS(3DVg),were recorded.The size of the SCH and its ratio to the GS size(Cs/Cg,Ss/Sg,3DVs/3DVg)were recorded and compared.RESULTS Compared with those in the normal pregnancy group,the adverse pregnancy group had higher Cs/Cg,Ss/Sg,and 3DVs/3DVg ratios(P<0.05).When 3DVs/3DVg was 0.220,the highest predictive performance predicted adverse pregnancy outcomes,resulting in an AUC of 0.767,and the sensitivity,specificity were 70.2%,75%respectively.VOCAL measuring 3DVs/3DVg combined with serum progesterone gave a diagnostic AUC of 0.824 for early pregnancy outcome in SCH patients,with a high sensitivity of 82.1%and a specificity of 72.1%,which showed a significant difference between AUC.CONCLUSION VOCAL-measured 3DVs/3DVg effectively quantifies the severity of SCH,while combined serum progesterone better predicts adverse pregnancy outcomes.展开更多
We focus on the goal of undergraduate talent training,consider the course features of Road Engineering Construction Technology and Organization,analyze the problems existing in the practical teaching of the course,use...We focus on the goal of undergraduate talent training,consider the course features of Road Engineering Construction Technology and Organization,analyze the problems existing in the practical teaching of the course,use the advantages of BIM+virtual simulation technology,design a scientific and reasonable practical teaching content of Road Engineering Construction Technology and Organization,and address the contrast between the strong practical aspect of the traditional Road Engineering Construction Technology and Organization course and the lack of practical instruments in hope to improve students’learning autonomy,enhance the quality of practical teaching,achieve the training objectives of the course,and nurture applied technical talents.展开更多
目的:评估二维超声(2D-US)、三维超声VOCAL技术(3D-VOCAL)对子宫肌瘤体积(UMV)测量的精确性。方法:选取2022年10月~2023年4月于福建医科大学附属龙岩第一医院行子宫肌瘤外科手术治疗的患者45例,术前运用2D-US、3D-VOCAL对UMV进行测量,...目的:评估二维超声(2D-US)、三维超声VOCAL技术(3D-VOCAL)对子宫肌瘤体积(UMV)测量的精确性。方法:选取2022年10月~2023年4月于福建医科大学附属龙岩第一医院行子宫肌瘤外科手术治疗的患者45例,术前运用2D-US、3D-VOCAL对UMV进行测量,与手术切除后的实际肌瘤体积进行比较,评估两种超声技术测量UMV的准确性及重复性。结果:3D-VOCAL测量肌瘤体积的一致性(ICC=0.992)高于2D-US(ICC=0.976),且3D-VOCAL在不同大小肌瘤中的ICC均高于2D-US(均P<0.001)。2D-US、3D-VOCAL、手术术后3组间UMV测值的体积在最大径<8 cm差异无统计学意义(P>0.05),而3组间在最大径≥8 cm差异有统计学意义(P<0.05);进一步两两分析显示,在最大径≥8 cm UMV中,2D-US与手术术后的UMV测值差异有统计学意义(P<0.05),3D-VOCAL与手术术后的UMV测值差异无统计学意义(P>0.05)。3D-VOCAL在不同观察者间及观察者内的一致性均优于2D-US。结论:3D-VOCAL对于术前UMV的测量优于2D-US,是一种简便、高效的可靠方法,为临床随访提供理论依据。展开更多
The problem of constructing global view of heterogeneous information sources for information sharing is becoming more and more important due to the availability of multiple information sources within the virtual organ...The problem of constructing global view of heterogeneous information sources for information sharing is becoming more and more important due to the availability of multiple information sources within the virtual organization. Global view is defined to provide a unified representation of the information in the different sources by analyzing concept schemas associated with them and resolving possible semantic heterogeneity. An ontology-based method for global view construction is proposed. In the method, ( 1 ) Based on the formal ontologies, the concept of semantic affinity is introduced to assess the level of semantic relationship between information classes from different information sources; (2) Information classes are classified by semantic affinity levels using clustering procedures so that their different representations can be analyzed for unification; (3) Global view is constructed starting from selected clusters by unifying representation of their elements. The application example of using the method in the joint-aerial defense organization is illustrated and the result shows that the proposed method is feasible.展开更多
It is now possible to organize globally while worki ng locally: Information technologies like e-mail, the Internet, and video confere ncing to the desktop permit tight coordination of geographically dispersed worke rs...It is now possible to organize globally while worki ng locally: Information technologies like e-mail, the Internet, and video confere ncing to the desktop permit tight coordination of geographically dispersed worke rs across time zones and cultures. Companies are not limited to physical locatio ns for providing products and services. Networked information systems are allowi ng companies to coordinate their geographically distributed capabilities as virt ual organizations. In order for organizations to succeed, they must be able to r espond with agility in a geographically dispersed environment. The core for a vi rtual organization to increase the utilization rate of resources to the maxi mum and to make full use of the transient market opportunities lies in how to br ing the potential of information technology into play. Based on the philosophy o f agile manufacturing, this paper analyses the basic concepts and connotation of Virtual Organization Information systems(VOIS). VOIS is an information system composed of some independent information subsystems that are autonomous, collab orative and belong to umpty organizations respectively. VOIS support the operati on of virtual organization, and automate the information flow across organizatio nal boundaries. Such systems have capabilities as rapid construction, quick oper ation, and agile reengineering and swift adaptability. Differences between VOIS and traditional enterprise information systems are analyzed. On the basis of ana lyzing the structure of VOIS, an abstract hierarchical structure of VOIS is prop osed using object-oriented method. Reengineering ideology and methods of VOIS a re also explored in light of the three layers structure.展开更多
Based on the definition of technology innovation of agricultural leading enterprises by domestic and foreign experts and scholars,technology innovation of agricultural enterprises is a process of new market increment,...Based on the definition of technology innovation of agricultural leading enterprises by domestic and foreign experts and scholars,technology innovation of agricultural enterprises is a process of new market increment,which uses new knowledge,technology,process and production mode,produces new products,offers new services and realizes commercialization. Characteristics of agricultural technology innovation are introduced,such as obvious regionality,relatively high risk,long-term periodicity and public attribute. Predicament for technology innovation of leading enterprises is analyzed,such as technical constraints,financial constraints and personnel constraints. Technological Innovation Mode can be classified into three modes of independent innovation,imitative innovation and cooperative innovation by the method of technology innovation. Among them,since there are some defects in the technology innovation process,independent innovation and imitative innovation are generally not used for the innovation of agricultural enterprises. Cooperative Innovation Mode can rely on foreign aid,can realize complementary advantages and achievement sharing,and can be widely applied in the agricultural innovation enterprise. Virtual organization in cooperation innovation mode is described,which makes up for technology,capital and human resources barriers in the process of agricultural enterprise innovation. Therefore,this mode is popular among the agricultural innovation enterprise.展开更多
The evaluation of estrogenic activities and aryl hydrocarbon receptor (AhR) agonists in water from Three Gorges Reservoir (TGR) China was conducted by in vitro bioassays combined with SPMD-based virtual organisms (VO)...The evaluation of estrogenic activities and aryl hydrocarbon receptor (AhR) agonists in water from Three Gorges Reservoir (TGR) China was conducted by in vitro bioassays combined with SPMD-based virtual organisms (VO). VOs were deployed at seven sites in the Three Gorges Reservoir (TGR), China for two periods in 2009. The estrogenic activity was assessed using a rapid yeast estrogen bioassay, based on the expression of a green fluorescent reporter protein (yEGFP). The AhR activity was detected employing rat hepatoma cell line (H4IIE). The results indicate that AhR agonists distributed widely in water of TGR and almost homogenously distributed in most area of TGR. Weak antiestrogenic activities were also found homogenously distributed in water of TGR. Further studies are needed to determine the identities of these estrogenic compounds and AhR agonists and their potential adverse effects on wild biota in TGR.展开更多
This paper discusses an organizational model to be used for both conventional and virtual organizations. The model deals with variable relationships within an organization and provides a framework for overall organiza...This paper discusses an organizational model to be used for both conventional and virtual organizations. The model deals with variable relationships within an organization and provides a framework for overall organizational design that may include relationship among different design variables and external relationship with environment. Based on the researches of virtual organization, this paper also illustrates the new model of organization in the real world such as Beijing 2008 Olympic games and Dongfeng Automobile group.展开更多
目的探讨抗核抗体(ANA)与低分子肝素(LMWH)治疗不明原因复发性流产(URSA)孕妇子宫胎盘血流指数的关系。方法2020年1月至2022年12月期间,共纳入80例URSA孕妇,其中40例接受LMWH治疗,另外40例未接受LMWH治疗,2组ANA阴性(-)和ANA阳性(+)各2...目的探讨抗核抗体(ANA)与低分子肝素(LMWH)治疗不明原因复发性流产(URSA)孕妇子宫胎盘血流指数的关系。方法2020年1月至2022年12月期间,共纳入80例URSA孕妇,其中40例接受LMWH治疗,另外40例未接受LMWH治疗,2组ANA阴性(-)和ANA阳性(+)各20例。借助虚拟器官计算机辅助分析技术进行2D多普勒测量子宫动脉搏动指数(PI)和3D超声测定血管化指数(VI)、血流指数(FI)和血管化血流指数(VFI),并对所有女性进行血清ANA测定。结果未接受LMWH治疗和接受LMWH治疗的ANA(-)URSA孕妇分娩孕周、新生儿结局比较,差异具有统计学意义(P<0.05)。无论ANA状态如何,未接受LMWH治疗和接受LMWH治疗的URSA孕妇间PI、VFI、FI值差异均无统计学意义(P>0.05)。而接受LMWH治疗的ANA(-)URSA孕妇VI值显著高于未接受LMWH治疗的ANA(-)URSA孕妇(20.02±6.06 vs 11.60±3.04,P<0.001)。仅考虑ANA(-)URSA患者,VI用于区分接受和未接受LMWH治疗孕妇的ROC曲线下面积为0.889(标准误=0.053,P<0.001,95%置信区间=0.785~0.993),VI临界值为16.05,灵敏度为75.0%,特异性为100.0%。结论LMWH可能对于恢复ANA(-)状态下URSA女性VI的生理血流供应具有潜在的有益作用,但是仍需要更进一步的研究来解释彼此之间的关系。展开更多
文摘BACKGROUND Subchorionic hematoma(SCH)is a common complication in early pregnancy characterized by the accumulation of blood between the uterine wall and the chorionic membrane.SCH can lead to adverse pregnancy outcomes such as miscarriage,preterm birth,and other complications.Early detection and accurate assessment of SCH are crucial for appropriate management and improved pregnancy outcomes.AIM To evaluate the diagnostic efficacy of virtual organ computer-assisted analysis(VOCAL)in measuring the volume ratio of SCH to gestational sac(GS)combined with serum progesterone on early pregnancy outcomes in patients with SCH.METHODS A total of 153 patients with SCH in their first-trimester pregnancies between 6 and 11 wk were enrolled.All patients were followed up until a gestational age of 20 wk.The parameters of transvaginal two-dimensional ultrasound,including the circumference of SCH(Cs),surface area of SCH(Ss),circumference of GS(Cg),and surface area of GS(Sg),and the parameters of VOCAL with transvaginal three-dimensional ultrasound,including the three-dimensional volume of SCH(3DVs)and GS(3DVg),were recorded.The size of the SCH and its ratio to the GS size(Cs/Cg,Ss/Sg,3DVs/3DVg)were recorded and compared.RESULTS Compared with those in the normal pregnancy group,the adverse pregnancy group had higher Cs/Cg,Ss/Sg,and 3DVs/3DVg ratios(P<0.05).When 3DVs/3DVg was 0.220,the highest predictive performance predicted adverse pregnancy outcomes,resulting in an AUC of 0.767,and the sensitivity,specificity were 70.2%,75%respectively.VOCAL measuring 3DVs/3DVg combined with serum progesterone gave a diagnostic AUC of 0.824 for early pregnancy outcome in SCH patients,with a high sensitivity of 82.1%and a specificity of 72.1%,which showed a significant difference between AUC.CONCLUSION VOCAL-measured 3DVs/3DVg effectively quantifies the severity of SCH,while combined serum progesterone better predicts adverse pregnancy outcomes.
基金the Chongqing Engineering College Educational Teaching Reform Research Project“Practical Teaching Research of Road Engineering Construction Technology and Organization Course Based on BIM+Virtual Simulation Technology”(Project No.JY2021310).
文摘We focus on the goal of undergraduate talent training,consider the course features of Road Engineering Construction Technology and Organization,analyze the problems existing in the practical teaching of the course,use the advantages of BIM+virtual simulation technology,design a scientific and reasonable practical teaching content of Road Engineering Construction Technology and Organization,and address the contrast between the strong practical aspect of the traditional Road Engineering Construction Technology and Organization course and the lack of practical instruments in hope to improve students’learning autonomy,enhance the quality of practical teaching,achieve the training objectives of the course,and nurture applied technical talents.
文摘目的:评估二维超声(2D-US)、三维超声VOCAL技术(3D-VOCAL)对子宫肌瘤体积(UMV)测量的精确性。方法:选取2022年10月~2023年4月于福建医科大学附属龙岩第一医院行子宫肌瘤外科手术治疗的患者45例,术前运用2D-US、3D-VOCAL对UMV进行测量,与手术切除后的实际肌瘤体积进行比较,评估两种超声技术测量UMV的准确性及重复性。结果:3D-VOCAL测量肌瘤体积的一致性(ICC=0.992)高于2D-US(ICC=0.976),且3D-VOCAL在不同大小肌瘤中的ICC均高于2D-US(均P<0.001)。2D-US、3D-VOCAL、手术术后3组间UMV测值的体积在最大径<8 cm差异无统计学意义(P>0.05),而3组间在最大径≥8 cm差异有统计学意义(P<0.05);进一步两两分析显示,在最大径≥8 cm UMV中,2D-US与手术术后的UMV测值差异有统计学意义(P<0.05),3D-VOCAL与手术术后的UMV测值差异无统计学意义(P>0.05)。3D-VOCAL在不同观察者间及观察者内的一致性均优于2D-US。结论:3D-VOCAL对于术前UMV的测量优于2D-US,是一种简便、高效的可靠方法,为临床随访提供理论依据。
基金This project was supported by the National Natural Science Foundation of China (60172012) Hunan Provincial NaturalScience Foundation of China (03JJY3110) .
文摘The problem of constructing global view of heterogeneous information sources for information sharing is becoming more and more important due to the availability of multiple information sources within the virtual organization. Global view is defined to provide a unified representation of the information in the different sources by analyzing concept schemas associated with them and resolving possible semantic heterogeneity. An ontology-based method for global view construction is proposed. In the method, ( 1 ) Based on the formal ontologies, the concept of semantic affinity is introduced to assess the level of semantic relationship between information classes from different information sources; (2) Information classes are classified by semantic affinity levels using clustering procedures so that their different representations can be analyzed for unification; (3) Global view is constructed starting from selected clusters by unifying representation of their elements. The application example of using the method in the joint-aerial defense organization is illustrated and the result shows that the proposed method is feasible.
文摘It is now possible to organize globally while worki ng locally: Information technologies like e-mail, the Internet, and video confere ncing to the desktop permit tight coordination of geographically dispersed worke rs across time zones and cultures. Companies are not limited to physical locatio ns for providing products and services. Networked information systems are allowi ng companies to coordinate their geographically distributed capabilities as virt ual organizations. In order for organizations to succeed, they must be able to r espond with agility in a geographically dispersed environment. The core for a vi rtual organization to increase the utilization rate of resources to the maxi mum and to make full use of the transient market opportunities lies in how to br ing the potential of information technology into play. Based on the philosophy o f agile manufacturing, this paper analyses the basic concepts and connotation of Virtual Organization Information systems(VOIS). VOIS is an information system composed of some independent information subsystems that are autonomous, collab orative and belong to umpty organizations respectively. VOIS support the operati on of virtual organization, and automate the information flow across organizatio nal boundaries. Such systems have capabilities as rapid construction, quick oper ation, and agile reengineering and swift adaptability. Differences between VOIS and traditional enterprise information systems are analyzed. On the basis of ana lyzing the structure of VOIS, an abstract hierarchical structure of VOIS is prop osed using object-oriented method. Reengineering ideology and methods of VOIS a re also explored in light of the three layers structure.
基金Supported by the Social Science Planning Program of Beijing Municipal Commission of Education (SM201010020003)
文摘Based on the definition of technology innovation of agricultural leading enterprises by domestic and foreign experts and scholars,technology innovation of agricultural enterprises is a process of new market increment,which uses new knowledge,technology,process and production mode,produces new products,offers new services and realizes commercialization. Characteristics of agricultural technology innovation are introduced,such as obvious regionality,relatively high risk,long-term periodicity and public attribute. Predicament for technology innovation of leading enterprises is analyzed,such as technical constraints,financial constraints and personnel constraints. Technological Innovation Mode can be classified into three modes of independent innovation,imitative innovation and cooperative innovation by the method of technology innovation. Among them,since there are some defects in the technology innovation process,independent innovation and imitative innovation are generally not used for the innovation of agricultural enterprises. Cooperative Innovation Mode can rely on foreign aid,can realize complementary advantages and achievement sharing,and can be widely applied in the agricultural innovation enterprise. Virtual organization in cooperation innovation mode is described,which makes up for technology,capital and human resources barriers in the process of agricultural enterprise innovation. Therefore,this mode is popular among the agricultural innovation enterprise.
文摘The evaluation of estrogenic activities and aryl hydrocarbon receptor (AhR) agonists in water from Three Gorges Reservoir (TGR) China was conducted by in vitro bioassays combined with SPMD-based virtual organisms (VO). VOs were deployed at seven sites in the Three Gorges Reservoir (TGR), China for two periods in 2009. The estrogenic activity was assessed using a rapid yeast estrogen bioassay, based on the expression of a green fluorescent reporter protein (yEGFP). The AhR activity was detected employing rat hepatoma cell line (H4IIE). The results indicate that AhR agonists distributed widely in water of TGR and almost homogenously distributed in most area of TGR. Weak antiestrogenic activities were also found homogenously distributed in water of TGR. Further studies are needed to determine the identities of these estrogenic compounds and AhR agonists and their potential adverse effects on wild biota in TGR.
文摘This paper discusses an organizational model to be used for both conventional and virtual organizations. The model deals with variable relationships within an organization and provides a framework for overall organizational design that may include relationship among different design variables and external relationship with environment. Based on the researches of virtual organization, this paper also illustrates the new model of organization in the real world such as Beijing 2008 Olympic games and Dongfeng Automobile group.
文摘目的探讨抗核抗体(ANA)与低分子肝素(LMWH)治疗不明原因复发性流产(URSA)孕妇子宫胎盘血流指数的关系。方法2020年1月至2022年12月期间,共纳入80例URSA孕妇,其中40例接受LMWH治疗,另外40例未接受LMWH治疗,2组ANA阴性(-)和ANA阳性(+)各20例。借助虚拟器官计算机辅助分析技术进行2D多普勒测量子宫动脉搏动指数(PI)和3D超声测定血管化指数(VI)、血流指数(FI)和血管化血流指数(VFI),并对所有女性进行血清ANA测定。结果未接受LMWH治疗和接受LMWH治疗的ANA(-)URSA孕妇分娩孕周、新生儿结局比较,差异具有统计学意义(P<0.05)。无论ANA状态如何,未接受LMWH治疗和接受LMWH治疗的URSA孕妇间PI、VFI、FI值差异均无统计学意义(P>0.05)。而接受LMWH治疗的ANA(-)URSA孕妇VI值显著高于未接受LMWH治疗的ANA(-)URSA孕妇(20.02±6.06 vs 11.60±3.04,P<0.001)。仅考虑ANA(-)URSA患者,VI用于区分接受和未接受LMWH治疗孕妇的ROC曲线下面积为0.889(标准误=0.053,P<0.001,95%置信区间=0.785~0.993),VI临界值为16.05,灵敏度为75.0%,特异性为100.0%。结论LMWH可能对于恢复ANA(-)状态下URSA女性VI的生理血流供应具有潜在的有益作用,但是仍需要更进一步的研究来解释彼此之间的关系。