新引进药用植物VUKA（Mondia whitei L.）对小鼠喂饲之安全性评估

For the purpose to investigate the safety of utilizing VUKA (Mondia whitei L.), we processed the acute oral toxicity test in ICR mice. There was no mouse dead after given with VUKA extracts during the time course, so the LD50 of water-extracted and freeze-dried powder of VUKA was estimated over 15 g/kg body weight for mice. No significant lesions of brain, heart, liver, kidney, spleen and thymus were found at gross and histopathological observation in the treated mice. Hematological parameters included of WBC, RBC, HGB, HCT, MCV, MCH, MCHC and PLT values were as normal as control. Besides, serum biochemistry changes in liver and renal function included of ALT, AST and creatinine values had no significant difference (p＞0.05) with control.

“乌卡时代”和“巴尼时代”叠加期的韧性城市规划、建设与治理

近年来,全球各地及我国部分地区出现的极端气候事件、疫情、经济金融挑战等各类灰犀牛、黑天鹅事件的出现,表明人类已经进入一个全新的“乌卡时代”和“巴尼时代”叠加期,生态环境压力加大,发展的不确定性、不稳定性和脆弱性在城市尤其是大城市表现更加明显,未来城市人居环境的波动性、不确定性、复杂性和脆弱性加剧。在此背景下,提高发展的韧性,建设韧性城市意义重大。为此,本文在系统梳理国内外韧性城市理论及实践的基础上,围绕我国韧性城市的规划、建设和治理对策展开探讨,强调更加关注空间正义,构建参与式治理及重视地方性,同时高度关注居民身心健康、充分利用多源数据和人工智能等新技术、加强跨领域研究和国际合作,积极应对新挑战。