目的探讨自体腘绳肌腱植入治疗重度阴道前壁脱垂的安全性和中期疗效。方法本研究为单臂临床试验,2021年5月开始纳入有症状、要求手术治疗的以阴道前壁重度脱垂为主的盆腔器官脱垂(pelvic organ prolapse,POP)患者,经患者充分知情,自愿...目的探讨自体腘绳肌腱植入治疗重度阴道前壁脱垂的安全性和中期疗效。方法本研究为单臂临床试验,2021年5月开始纳入有症状、要求手术治疗的以阴道前壁重度脱垂为主的盆腔器官脱垂(pelvic organ prolapse,POP)患者,经患者充分知情,自愿选择自体腘绳肌腱添加修补,同时行双侧高位骶韧带悬吊。术后随访盆腔器官脱垂定量分度(pelvic organ prolapse quantification,POP-Q)、盆底不适调查表简表评分(Pelvic Floor Distress Inventory-Short Form 20,PFDI-20)、术后满意度评分、患者整体印象改善评分(Patient Global Impression of Improvement,PGI-I)。观察术后取腱侧下肢功能及术后并发症处理、再手术情况。结果取腱手术时间(19.7±8.3)min,盆底手术时间(122.1±37.8)min,术中出血量中位数70 ml(50~400 ml),无术中副损伤和术后病率。12例随访(26.4±2.5)月。Aa、Ba、C术前分别为3(-1~3)、5(2~10)、4(-1~10),术后24个月分别为-3(-3~3)、-3(-3~3)、-6(-6~3),差异有显著性(P<0.05)。12例术前、术后24个月PFDI-20评分分别为88.0(16.7~204.2)、8.3(0~32.3)分,差异有显著性(Z=-2.803,P=0.005);PGI-I问卷11例术后症状明显改善,1例有改善。术后6、24个月满意度评分分别为(4.8±0.4)分和(4.6±0.7)分。1例术后12个月自感阴道脱出物,阴道前壁及顶端脱垂Ⅲ度,复发率8.3%(1/12)。2例分别术后9 d、2周肺栓塞,Clavien-Dindo外科手术并发症分级分别为Ⅱ、Ⅲ级,分别门诊和住院治疗后痊愈。1例阴道顶端局部筋膜暴露,药物治疗好转。所有患者取腱部位切口愈合良好,肌力、下肢活动均正常。无因复发和筋膜条并发症再次手术。结论自体腘绳肌腱植入治疗重度阴道前壁脱垂手术安全,中期疗效满意。术前需向患者宣教下肢锻炼预防静脉血栓并发症。展开更多
Objective:To investigate the clinical effects of laparoscopic lateral peritoneal suspension for severe pelvic organ prolapse(POP).Methods:Thirty-eight patients who underwent laparoscopic lateral peritoneal suspension ...Objective:To investigate the clinical effects of laparoscopic lateral peritoneal suspension for severe pelvic organ prolapse(POP).Methods:Thirty-eight patients who underwent laparoscopic lateral peritoneal suspension for pelvic organ prolapse in the gynecology department of our hospital from January 2019 to January 2020 were selected for retrospective analysis.Postoperative outcomes were recorded for patients at 3,6,and 12 months postoperatively.Results:All 38 patients completed the surgery safely,and the duration of surgery was 85-190 min,with a mean of(138±40.75)min;surgical bleeding was 30-80 ml,with a mean of(57±35.4)ml;the duration of postoperative catheterization was 4-6 days,with a mean of(5±0.73)days;postoperative hospitalization was 6-12 days,with a mean of(8.49±2.18)days.2.18)days.At 3,6,and 12 months after the end of surgery,all follow-up patients had their uterus and anterior vaginal wall restored to normal position without prolapse.The pelvic floor rehabilitation of the patients after surgery was good and their sexual life was significantly improved in all cases.Conclusion:Laparoscopic lateral peritoneal suspension for severe pelvic organ prolapse is safe,efficacious,minimally traumatic,less painful,with short hospital stay,fast postoperative recovery,greater choice of uterine de-positioning,with the advantages of permanence and good pelvic floor anatomical recovery,and this procedure can maintain a certain vaginal length with 100%efficiency,which is worthy of clinical promotion.展开更多
文摘目的探讨自体腘绳肌腱植入治疗重度阴道前壁脱垂的安全性和中期疗效。方法本研究为单臂临床试验,2021年5月开始纳入有症状、要求手术治疗的以阴道前壁重度脱垂为主的盆腔器官脱垂(pelvic organ prolapse,POP)患者,经患者充分知情,自愿选择自体腘绳肌腱添加修补,同时行双侧高位骶韧带悬吊。术后随访盆腔器官脱垂定量分度(pelvic organ prolapse quantification,POP-Q)、盆底不适调查表简表评分(Pelvic Floor Distress Inventory-Short Form 20,PFDI-20)、术后满意度评分、患者整体印象改善评分(Patient Global Impression of Improvement,PGI-I)。观察术后取腱侧下肢功能及术后并发症处理、再手术情况。结果取腱手术时间(19.7±8.3)min,盆底手术时间(122.1±37.8)min,术中出血量中位数70 ml(50~400 ml),无术中副损伤和术后病率。12例随访(26.4±2.5)月。Aa、Ba、C术前分别为3(-1~3)、5(2~10)、4(-1~10),术后24个月分别为-3(-3~3)、-3(-3~3)、-6(-6~3),差异有显著性(P<0.05)。12例术前、术后24个月PFDI-20评分分别为88.0(16.7~204.2)、8.3(0~32.3)分,差异有显著性(Z=-2.803,P=0.005);PGI-I问卷11例术后症状明显改善,1例有改善。术后6、24个月满意度评分分别为(4.8±0.4)分和(4.6±0.7)分。1例术后12个月自感阴道脱出物,阴道前壁及顶端脱垂Ⅲ度,复发率8.3%(1/12)。2例分别术后9 d、2周肺栓塞,Clavien-Dindo外科手术并发症分级分别为Ⅱ、Ⅲ级,分别门诊和住院治疗后痊愈。1例阴道顶端局部筋膜暴露,药物治疗好转。所有患者取腱部位切口愈合良好,肌力、下肢活动均正常。无因复发和筋膜条并发症再次手术。结论自体腘绳肌腱植入治疗重度阴道前壁脱垂手术安全,中期疗效满意。术前需向患者宣教下肢锻炼预防静脉血栓并发症。
文摘Objective:To investigate the clinical effects of laparoscopic lateral peritoneal suspension for severe pelvic organ prolapse(POP).Methods:Thirty-eight patients who underwent laparoscopic lateral peritoneal suspension for pelvic organ prolapse in the gynecology department of our hospital from January 2019 to January 2020 were selected for retrospective analysis.Postoperative outcomes were recorded for patients at 3,6,and 12 months postoperatively.Results:All 38 patients completed the surgery safely,and the duration of surgery was 85-190 min,with a mean of(138±40.75)min;surgical bleeding was 30-80 ml,with a mean of(57±35.4)ml;the duration of postoperative catheterization was 4-6 days,with a mean of(5±0.73)days;postoperative hospitalization was 6-12 days,with a mean of(8.49±2.18)days.2.18)days.At 3,6,and 12 months after the end of surgery,all follow-up patients had their uterus and anterior vaginal wall restored to normal position without prolapse.The pelvic floor rehabilitation of the patients after surgery was good and their sexual life was significantly improved in all cases.Conclusion:Laparoscopic lateral peritoneal suspension for severe pelvic organ prolapse is safe,efficacious,minimally traumatic,less painful,with short hospital stay,fast postoperative recovery,greater choice of uterine de-positioning,with the advantages of permanence and good pelvic floor anatomical recovery,and this procedure can maintain a certain vaginal length with 100%efficiency,which is worthy of clinical promotion.
