Rationale:Vanishing lung syndrome is rare and can be associated with a history of smoking and marijuana use.The occurrence of giant bullae can also be linked to infections,particularly tuberculosis in tropical countri...Rationale:Vanishing lung syndrome is rare and can be associated with a history of smoking and marijuana use.The occurrence of giant bullae can also be linked to infections,particularly tuberculosis in tropical countries.Patient concerns:A 26-year-old male complained of weakness,severe vomiting,and reduced breathlessness when lying on the left side.He had a history of pulmonary tuberculosis two years ago.Diagnosis:Symptomatic bradycardia in tuberculosis-related giant bullae.Interventions:The patient was recommended to undergo an elective bullectomy,but he decided not to proceed with the procedure.Atropine sulfate was administered to alleviate symptoms of bradycardia,while a standardized anti-tuberculosis regimen were started for the next six months.Outcomes:Following 7 days of intensive care treatment involving antituberculosis medications and atropine sulfate,the patient achieved hemodynamic stability,opting against bullectomy despite residual symptoms of dyspnea.Subsequent six months of antituberculosis therapy notably alleviated symptoms without requiring bullectomy.Lessons:Increasing intrathoracic pressure can also be caused mechanically by giant bullae.Cardiac symptoms in vanishing lung syndrome are reversible and can be alleviated once the underlying cause is addressed.In this case,symptomatic bradycardia was reduced only with tuberculosis treatment without bullectomy intervention。展开更多
Background: Vanishing lung is a rare syndrome. It mainly affects young males who are smokers, it considered an advanced stage of bullous disease, where the entire lobe or lung paranchym is replaced by bullae, it appea...Background: Vanishing lung is a rare syndrome. It mainly affects young males who are smokers, it considered an advanced stage of bullous disease, where the entire lobe or lung paranchym is replaced by bullae, it appears radiologically as a hyperlucency due to air trapping and destruction of interstitial tissue and vascularity in alveolar wall’s. Misdiagnosed usually as pneumothorax so must be differentiated from other causes of Hyperlucency lung syndrom. Hereby a case of vanishing lung diagnosed primarily as a post TB lung destruction. Case Report: A sixteenth-year-old virgin female patient, with treated for TB for six months without radilogical improvement. CXR and CT scan revealed diffuse left lung hyperlucency, TB work up (sputum exam, washing by bronchoscopy) appears no active disease. Left pneumenctomy had done, grossly there are no lung pranchyma and microscopically no signs of TB in the specimen. The findings are consistent with Vanishing lung. Conclusions: An understanding of the broad differential diagnosis of pulmonary hyperlucency is necessary to determine the underlying cause and provide appropriate patient care.展开更多
文摘Rationale:Vanishing lung syndrome is rare and can be associated with a history of smoking and marijuana use.The occurrence of giant bullae can also be linked to infections,particularly tuberculosis in tropical countries.Patient concerns:A 26-year-old male complained of weakness,severe vomiting,and reduced breathlessness when lying on the left side.He had a history of pulmonary tuberculosis two years ago.Diagnosis:Symptomatic bradycardia in tuberculosis-related giant bullae.Interventions:The patient was recommended to undergo an elective bullectomy,but he decided not to proceed with the procedure.Atropine sulfate was administered to alleviate symptoms of bradycardia,while a standardized anti-tuberculosis regimen were started for the next six months.Outcomes:Following 7 days of intensive care treatment involving antituberculosis medications and atropine sulfate,the patient achieved hemodynamic stability,opting against bullectomy despite residual symptoms of dyspnea.Subsequent six months of antituberculosis therapy notably alleviated symptoms without requiring bullectomy.Lessons:Increasing intrathoracic pressure can also be caused mechanically by giant bullae.Cardiac symptoms in vanishing lung syndrome are reversible and can be alleviated once the underlying cause is addressed.In this case,symptomatic bradycardia was reduced only with tuberculosis treatment without bullectomy intervention。
文摘Background: Vanishing lung is a rare syndrome. It mainly affects young males who are smokers, it considered an advanced stage of bullous disease, where the entire lobe or lung paranchym is replaced by bullae, it appears radiologically as a hyperlucency due to air trapping and destruction of interstitial tissue and vascularity in alveolar wall’s. Misdiagnosed usually as pneumothorax so must be differentiated from other causes of Hyperlucency lung syndrom. Hereby a case of vanishing lung diagnosed primarily as a post TB lung destruction. Case Report: A sixteenth-year-old virgin female patient, with treated for TB for six months without radilogical improvement. CXR and CT scan revealed diffuse left lung hyperlucency, TB work up (sputum exam, washing by bronchoscopy) appears no active disease. Left pneumenctomy had done, grossly there are no lung pranchyma and microscopically no signs of TB in the specimen. The findings are consistent with Vanishing lung. Conclusions: An understanding of the broad differential diagnosis of pulmonary hyperlucency is necessary to determine the underlying cause and provide appropriate patient care.