Objective： To observe the therapeutic effect and effect on plasm endothelin （ET） and nitric oxide （NO） of acupuncture in treating variant angina pectoris. Methods： Sixty-two patients with variant angina pectoris...Objective： To observe the therapeutic effect and effect on plasm endothelin （ET） and nitric oxide （NO） of acupuncture in treating variant angina pectoris. Methods： Sixty-two patients with variant angina pectoris were randomly divided into the acupuncture group of 32 cases and the control group of 30 cases. The patients in control group were treated by nitrate, Ca^2＋ antagonist and aspirin for 4 weeks. The patients in acupuncture group were treated by needling Neiguan （PC 6）, Sanyinjiao （SP 6）, Zusanli （ST 36）, Xinshu （BL 15） Taichong （LR 3） and Shenmen （HT 7） on the basis of western medicine.Results： In acupuncture group, 24 cases were markedly effective, 6 cases were effective and 2 cases got no effect. In control group, 20 cases were markedly effective, 5cases were effective and 5 cases got no effect. The therapeutic effect of acupuncture treatment was significantly prior to that of control treatment （x^2 = 95.4, P 〈 0. 05）. In acupuncture group, posttreatment plasm NO, 86.9±23.15 μmol/L, was markedly higher than pretreatment NO, 63.8±22. 07μmol/L. There was significant difference between them （t= 2.925, P〈 0.01）. In the two groups, plasm ET reduced after treatment. There was significant difference in plasm ET between posttreatment and pretreatment in the two groups （P 〈 0.01）. There was significant difference in reduced plasm ET after treatment between acupuncture group and control group （P 〈 0. 05）. Conclusion： Acupuncture in assistant treating variant angina pectoris could improve the clinical symptoms obviously and reduce the level of plasm ET and NO.展开更多
目的探讨冠状动脉造影、血管内超声在诊断变异型心绞痛患者中的临床价值。方法选择我院2007年12月至2009年3月临床诊断为冠心病患者23例,其中变异型心绞痛患者10例,稳定型心绞痛患者13例。对每位患者行冠状动脉造影及血管内超声检查,对...目的探讨冠状动脉造影、血管内超声在诊断变异型心绞痛患者中的临床价值。方法选择我院2007年12月至2009年3月临床诊断为冠心病患者23例,其中变异型心绞痛患者10例,稳定型心绞痛患者13例。对每位患者行冠状动脉造影及血管内超声检查,对病变斑块的性质、形态、部位、血管管腔面积狭窄程度、血管重构指数等指标进行分析。结果变异型心绞痛组与稳定型心绞痛组两组斑块偏心指数分别为0.90±0.06 vs 0.70±0.25,局部面积狭窄率分别为(53.56±3.88)%vs(68.66±14.52)%,管腔面积狭窄率分别为(41.23±23.91)%vs(63.10±14.64)%,以上指标两组差异有统计学意义(均P<0.05)。血管内超声检测病变血管重构指数,正性重构、负性重构在两组差异有统计学意义(P<0.05)。对于变异型心绞痛患者,以血管内超声为参照,以节段为基础,冠状动脉造影和血管内超声检测血管管腔平均狭窄程度差异有统计学意义(P<0.05)。冠状动脉造影和血管内超声检测轻中度管腔面积狭窄差异有统计学意义,重度管腔面积狭窄两者差异无统计学意义。结论变异型心绞痛患者冠状动脉目标斑块以偏心性斑块为主,血管管腔面积狭窄程度以轻中度狭窄为主,血管重构以正性重构为主。冠状动脉造影低估病变管腔面积狭窄程度。展开更多
文摘Objective： To observe the therapeutic effect and effect on plasm endothelin （ET） and nitric oxide （NO） of acupuncture in treating variant angina pectoris. Methods： Sixty-two patients with variant angina pectoris were randomly divided into the acupuncture group of 32 cases and the control group of 30 cases. The patients in control group were treated by nitrate, Ca^2＋ antagonist and aspirin for 4 weeks. The patients in acupuncture group were treated by needling Neiguan （PC 6）, Sanyinjiao （SP 6）, Zusanli （ST 36）, Xinshu （BL 15） Taichong （LR 3） and Shenmen （HT 7） on the basis of western medicine.Results： In acupuncture group, 24 cases were markedly effective, 6 cases were effective and 2 cases got no effect. In control group, 20 cases were markedly effective, 5cases were effective and 5 cases got no effect. The therapeutic effect of acupuncture treatment was significantly prior to that of control treatment （x^2 = 95.4, P 〈 0. 05）. In acupuncture group, posttreatment plasm NO, 86.9±23.15 μmol/L, was markedly higher than pretreatment NO, 63.8±22. 07μmol/L. There was significant difference between them （t= 2.925, P〈 0.01）. In the two groups, plasm ET reduced after treatment. There was significant difference in plasm ET between posttreatment and pretreatment in the two groups （P 〈 0.01）. There was significant difference in reduced plasm ET after treatment between acupuncture group and control group （P 〈 0. 05）. Conclusion： Acupuncture in assistant treating variant angina pectoris could improve the clinical symptoms obviously and reduce the level of plasm ET and NO.
文摘目的探讨冠状动脉造影、血管内超声在诊断变异型心绞痛患者中的临床价值。方法选择我院2007年12月至2009年3月临床诊断为冠心病患者23例,其中变异型心绞痛患者10例,稳定型心绞痛患者13例。对每位患者行冠状动脉造影及血管内超声检查,对病变斑块的性质、形态、部位、血管管腔面积狭窄程度、血管重构指数等指标进行分析。结果变异型心绞痛组与稳定型心绞痛组两组斑块偏心指数分别为0.90±0.06 vs 0.70±0.25,局部面积狭窄率分别为(53.56±3.88)%vs(68.66±14.52)%,管腔面积狭窄率分别为(41.23±23.91)%vs(63.10±14.64)%,以上指标两组差异有统计学意义(均P<0.05)。血管内超声检测病变血管重构指数,正性重构、负性重构在两组差异有统计学意义(P<0.05)。对于变异型心绞痛患者,以血管内超声为参照,以节段为基础,冠状动脉造影和血管内超声检测血管管腔平均狭窄程度差异有统计学意义(P<0.05)。冠状动脉造影和血管内超声检测轻中度管腔面积狭窄差异有统计学意义,重度管腔面积狭窄两者差异无统计学意义。结论变异型心绞痛患者冠状动脉目标斑块以偏心性斑块为主,血管管腔面积狭窄程度以轻中度狭窄为主,血管重构以正性重构为主。冠状动脉造影低估病变管腔面积狭窄程度。
