Effect of acupuncture plus medication on the pulmonary ventilation, IFN-y level and sleep quality in allergic rhinitis patients

Objective:To observe the effect of warm-unblocking acupuncture plus fluticasone propionate nasal spray on the pulmonary ventilation,level of interferon-y(IFN-y)and sleep quality in parents with allergic rhinitis(AR).Methods:A total of 112 AR patients were enrolled between January 2013 and August 2018 and were divided into an observation group and a control group by the random number table method,with 56 cases in each group.Patients in the observation group received warm-unblocking acupuncture plus fluticasone propionate nasal spray,and patients in the control group only received fluticasone propionate nasal spray.The nasal symptom score,pulmonary function indexes,the levels of IFN-y and interleukin(IL)-4 in serum,and sleep quality in the two groups were compared.Results:After treatment,the total effective rate in the observation group was higher than that in the control group(P<0.05).The nasal symptom score dropped in both groups after treatment(both P<0.05),and the score in the observation group was lower than that in the con trol group(P<0.05).The pulm onary ven tilati on indexes all in creased sign ificantly after treatment in the observation group(all P<0.05);the forced expiratory volume in 1 second(FEV1)to forced vital capacity(FVC)ratio(FEV1/FVC)and the forced expiratory flow at 50%,75%and 25%-75%of the vital capacity(FEF50%,FEF75%,FEF25%-75%)in creased after treatme nt in the control group(all P<0.05);the pulm onary ven tilati on in dexes were higher in the observati on group tha n those in the control group(all P<0.05).The level of IFN-y in creased sign ificantly after t reatment in the two groups(both P<0.05)and the level of IL-4 dropped significantly(both P<0.05);the observation group had a higher IFN-y level(P<0.05)and a lower IL-4 level(P<0.05)compared with the control group.Regarding the Pittsburgh sleep quality index(PSQI),the scores of subjective sleep quality,habitual sleep efficiency and sleep disturbances and the general PSQI score decreased significantly after treatment in both groups(all P<0.05),and the scores in the observation group were significantly lower than those in the control group(all P<0.05).Conclusion:Warm-unblocking acupuncture plus fluticasone propionate nasal spray can effectively control the clinical symptoms and improve pulmonary function in the treatment of AR;this approach can regulate the levels of IFN-y and IL-4 towards the normal range in AR patients;it can also improve patient's sleep quality.This method can produce more significant efficacy than fluticasone propionate nasal spray used alone.

BiPAP无创正压通气治疗COPD并发Ⅱ型呼吸衰竭32例疗效分析

目的观察BiPAP无创正压通气治疗COPD并发Ⅱ型呼吸衰竭的临床效果。方法32例COPD并发Ⅱ型呼吸衰竭患者在常规综合治疗的同时,选用BiPAP呼吸机行无创正压通气,选择合适口鼻面罩,设定参数S/T模式,预置呼吸频率12～16次/min,氧浓度30～35%左右,吸气压以8cmH2O开始,逐渐增加压力至20cmH2O,呼气压4cmH2O,每日上机二次,每次2～3h,3～7d为1疗程。在机械通气前、机械通气后2h、24h及通气结束时作血气分析,并观察临床效果。结果与治疗前相比,无创正压通气后2h、24h及治疗结束时,pH值改善(P<0.05),PaO2上升(P<0.01),PaCO2下降(P<0.01)。28例患者好转出院,2例患者病情加重,家属不同意气管插管而死亡,2例患者病情加重行气管插管机械通气治疗,其中1例死亡,1例成功撤机好转出院。结论BiPAP无创正压通气对COPD并发Ⅱ型呼吸衰竭患者疗效显著,避免了大部分气管插管或气管切开以及相应的并发症,减少病人的痛苦和医疗费用,使用方便,值得临床推广。

建筑物机械排烟与通风系统合用横向与竖向布置的分析

本文分析了当建筑物采用机械排烟系统与通风系统合用时，建筑物按照不同的建筑类型及防火分区的划分，采用横向布置或竖向布置的情况及注意事项。

温州市部分酒店集中空调通风系统卫生监测与分析

目的:调查分析温州市部分酒店集中空调通风系统的卫生状况,为卫生管理提供依据,预防和控制由空调细菌污染所带来的呼吸道传染病的传播和流行。方法:选取20家有集中空调通风系统的单位,分别对风管表面的积尘量、真菌总数、细菌总数、β-溶血性链球菌,送风中PM10、细菌和真菌总数,以及冷凝水和冷却水中的嗜肺军团菌进行检测和评价。结果:送风空气PM10合格率为40%(8/20),细菌总数的合格率为100%(20/20),真菌总数合格率为95%(19/20),β-溶血性链球菌等致病菌均未检出;风管表面积尘量合格率为30%(6/20),细菌总数合格率为95%(19/20),真菌总数合格率为50%(10/20),空调冷凝水嗜肺军团菌污染率为5%(1/20),空调冷却水嗜肺军团菌的污染率高达45%(9/20)。结论:温州部分酒店集中空调通风系统存在一定的污染,冷却水中嗜肺军团菌污染情况较为严重,应加强集中空调系统的清洗消毒和卫生监督管理。