A new iridoid glycoside,versibirioside（1）,and a known iridoid glycoside,verbaspinoside（2）,were isolated from the whole plant of Veronica sibirica L.Their structures were elucidated by spectroscopic methods,includi...A new iridoid glycoside,versibirioside（1）,and a known iridoid glycoside,verbaspinoside（2）,were isolated from the whole plant of Veronica sibirica L.Their structures were elucidated by spectroscopic methods,including 2D-NMR spectra.展开更多
In this study, our objective was to evaluate the antioxidant, cytotoxicity and collagen synthesis activity in vitro and also to test the anti-wrinkle effect of formulated cream containing Veronica officinalis extract ...In this study, our objective was to evaluate the antioxidant, cytotoxicity and collagen synthesis activity in vitro and also to test the anti-wrinkle effect of formulated cream containing Veronica officinalis extract in vivo. Antioxidant evaluation was based on the scavenging activity of free radicles (DPPH) and procollagen type 1 protein (P1P) synthesis test was performed in fibroblast cell. Clinical anti-wrinkle activity was performed on female subjects in placebo-controlled trail. Verbascoside (an isolated compound) showed higher (IC50 value of 36.24 ± 1.81 μg/ml) free radicle inhibition activity but weaker collagen synthesis activity. The ethanolic extract showed good inhibition to DPPH free radicals and also showed a significant effect in collagen synthesis activity without cytotoxicity. In the in vivo study, treatment with the formulated cream (Scoti-Speedwell) for 56 days significantly reduced the percentage of wrinkle area and length with 18.0% and 16.05%, respectively. Overall, Veronica officinalis extract containing product (Scoti-SpeedwellTM) can be regarded as a potent anti-wrinkle agent in human skin.展开更多
Veronica erciyasdagi （M. A. Fischer） C. Vural comb. ＆ stat. nov., previously regarded as a variety, is proposed as a new combination, based on the morphological characters and seed storage protein polymorphism pres...Veronica erciyasdagi （M. A. Fischer） C. Vural comb. ＆ stat. nov., previously regarded as a variety, is proposed as a new combination, based on the morphological characters and seed storage protein polymorphism presented in this study. In addition, information about the ecology and conservation status of Veronica erciyasdagi was reported. This taxon is endemic to central Anatolia, Turkey and is critically endangered.展开更多
Recent studies have suggested that reproductive interference, a deleterious interspecific interaction in the mating process, plays an important role in biological invasions. In the system of plant species, however, th...Recent studies have suggested that reproductive interference, a deleterious interspecific interaction in the mating process, plays an important role in biological invasions. In the system of plant species, however, the border with the pollen limitation has often been vague in past studies. This study, using field and laboratory experiments and field observations, examined the reproductive success of an endangered native herbaceous plant, Veronica polita lilacina, in the context of the reproductive interference by the alien congener, V. persica. The auto-pollination experiment confirmed that both species can usually produce seeds even without external conspecific pollens. Results of the artificial pollination experiment demonstrated that pollination with the heterospecific pollens significantly decreases the number of seeds in the native species, but not in the alien species. A transplant experiment revealed that the coexistence with the alien species reduced the fruiting success of the native species. Field observations have shown the interaction between two species in the native patch with only one intruding alien species. They demonstrated that native individuals placed closer to the alien individual suffered a greater decrease in fruiting success and the seed production and that the alien intruder produced no seed. These results demonstrate that species that could reproduce via the auto-pollination suffered the reproductive interference and that the native species also exert the resistive reproductive interference slightly. These interactions can explain the displacement pattern of the native species by the alien congener in Japan.展开更多
Present study was conducted to investigate the Cadmium (Cd) phytoextraction potential of two plants (Veronica anagallis-aquatic and Epilobium laxum Royle) for Cd removal from induced saline water. In hydroponic system...Present study was conducted to investigate the Cadmium (Cd) phytoextraction potential of two plants (Veronica anagallis-aquatic and Epilobium laxum Royle) for Cd removal from induced saline water. In hydroponic system, various concentrations of the Cd (50, 100, and 150 ppm) and NaCl salt (1000, 3000, and 6000 ppm) were used alone and in various combinations to evaluate the effect of salt (NaCl) concentrations on Cd absorption and accumulation in Veronica anagallis and Epilobium plants. The Cd at higher concentrations (100 and 150 ppm) significantly reduced the growth and biomass of both plants and addition of salt (NaCl) to growth media (Hoagland solution) further reduced the growth. The Cadmium (Cd) translocation factor (TF) of Epilobium plant was more than one (1), while the Veronica plant showed translocation factor less than 0.5. Veronica plant showed higher Bio-concentration factor (BCF) as more than 3.5 and Epilobium plant demonstrated Bio-concentration factor less than 1 (BCF 1 is a threshold limit for a plant to be hyper-accumulator of Cd). Conclusively, the Veronica anagallis plant is reported as Cd hyper-accumulator, while Epilobium laxum plant as non hyper-accumulator on the basis of BCF values in the present findings. Further study on Veronica and Epilobium plants is recommended.展开更多
目的:研究玄参科婆婆纳属植物水蔓菁(Veronica linariifolia Pall. ex Link subsp. dilatata(Nakai et Kitagawa)Hong)中的酚性化学成分。方法:采用75%乙醇提取,运用各种色谱方法进行化学成分的分离纯化,用理化方法及波谱手段解析其化...目的:研究玄参科婆婆纳属植物水蔓菁(Veronica linariifolia Pall. ex Link subsp. dilatata(Nakai et Kitagawa)Hong)中的酚性化学成分。方法:采用75%乙醇提取,运用各种色谱方法进行化学成分的分离纯化,用理化方法及波谱手段解析其化学结构。结果:分离并鉴定了14个酚性化合物,其中黄酮类7个,分别为3′,4′,5,6,7-五羟基黄酮-7-O-β-D-葡萄糖基-(1″→2′)-β-D-葡萄糖苷(Ⅰ)、4′,5,7-三羟基-3′,6-二甲氧基黄酮-7-O-β-D-葡萄糖苷(Ⅱ)、芹菜素-7-O-β-D-葡萄糖醛酸苷甲酯(Ⅲ)、芹菜素-7-O-β-D-葡萄糖醛酸苷乙酯(Ⅳ)、芹菜素-7-O-β-D-葡萄糖醛酸苷丁酯(Ⅴ)、芹菜素(Ⅵ)、木犀草素(Ⅶ);酚酸类5个,分别为香草酸(Ⅷ)、对羟基苯甲酸(Ⅸ)、原儿茶酸(Ⅹ)、原儿茶酸乙酯(Ⅺ)、异阿魏酸(Ⅻ),还分到儿茶酚(X)、大黄素(XⅣ)。结论:除化合物Ⅵ、Ⅶ外,其余均为在该植物中首次分得,其中化合物Ⅱ～Ⅴ、Ⅺ、X、X为该属植物中首次分得。展开更多
目的研究轮叶婆婆纳V eron ica sibirica中二萜类成分的体外抗癌作用。方法以T J905和H eL a细胞为研究对象,采用M TT法对获得的化合物进行抗癌活性初筛并对初筛活性高的化合物进行剂量依赖性实验,测定其IC50值。结果对轮叶婆婆纳石油...目的研究轮叶婆婆纳V eron ica sibirica中二萜类成分的体外抗癌作用。方法以T J905和H eL a细胞为研究对象,采用M TT法对获得的化合物进行抗癌活性初筛并对初筛活性高的化合物进行剂量依赖性实验,测定其IC50值。结果对轮叶婆婆纳石油醚及醋酸乙酯提取物中的7个二萜类化合物:二氢丹参酮Ⅰ(Ⅰ)、丹参酮Ⅰ(Ⅱ)、丹参酮ⅡA(Ⅲ)、隐丹参酮(Ⅳ)、婆婆纳对醌A(Ⅴ)、婆婆纳对醌B(Ⅵ)、弥罗松酚(Ⅶ)进行了体外抗肿瘤活性考察,表明化合物Ⅰ和Ⅳ具有显著的抗癌活性,化合物Ⅰ对T J905及H eL a细胞生长的IC50值分别为1.038、1.816μg/mL,化合物Ⅳ对T J905及H eL a细胞生长的IC50值分别为3.637、4.391μg/mL。结论轮叶婆婆纳中的二氢丹参酮Ⅰ和隐丹参酮对T J905及H eL a细胞具有较强的生长抑制活性。展开更多
文摘A new iridoid glycoside,versibirioside（1）,and a known iridoid glycoside,verbaspinoside（2）,were isolated from the whole plant of Veronica sibirica L.Their structures were elucidated by spectroscopic methods,including 2D-NMR spectra.
文摘In this study, our objective was to evaluate the antioxidant, cytotoxicity and collagen synthesis activity in vitro and also to test the anti-wrinkle effect of formulated cream containing Veronica officinalis extract in vivo. Antioxidant evaluation was based on the scavenging activity of free radicles (DPPH) and procollagen type 1 protein (P1P) synthesis test was performed in fibroblast cell. Clinical anti-wrinkle activity was performed on female subjects in placebo-controlled trail. Verbascoside (an isolated compound) showed higher (IC50 value of 36.24 ± 1.81 μg/ml) free radicle inhibition activity but weaker collagen synthesis activity. The ethanolic extract showed good inhibition to DPPH free radicals and also showed a significant effect in collagen synthesis activity without cytotoxicity. In the in vivo study, treatment with the formulated cream (Scoti-Speedwell) for 56 days significantly reduced the percentage of wrinkle area and length with 18.0% and 16.05%, respectively. Overall, Veronica officinalis extract containing product (Scoti-SpeedwellTM) can be regarded as a potent anti-wrinkle agent in human skin.
基金The present study is part of the project "EUBAP-FBT.04.46" supported by Erciyes University Research Fund
文摘Veronica erciyasdagi （M. A. Fischer） C. Vural comb. ＆ stat. nov., previously regarded as a variety, is proposed as a new combination, based on the morphological characters and seed storage protein polymorphism presented in this study. In addition, information about the ecology and conservation status of Veronica erciyasdagi was reported. This taxon is endemic to central Anatolia, Turkey and is critically endangered.
文摘Recent studies have suggested that reproductive interference, a deleterious interspecific interaction in the mating process, plays an important role in biological invasions. In the system of plant species, however, the border with the pollen limitation has often been vague in past studies. This study, using field and laboratory experiments and field observations, examined the reproductive success of an endangered native herbaceous plant, Veronica polita lilacina, in the context of the reproductive interference by the alien congener, V. persica. The auto-pollination experiment confirmed that both species can usually produce seeds even without external conspecific pollens. Results of the artificial pollination experiment demonstrated that pollination with the heterospecific pollens significantly decreases the number of seeds in the native species, but not in the alien species. A transplant experiment revealed that the coexistence with the alien species reduced the fruiting success of the native species. Field observations have shown the interaction between two species in the native patch with only one intruding alien species. They demonstrated that native individuals placed closer to the alien individual suffered a greater decrease in fruiting success and the seed production and that the alien intruder produced no seed. These results demonstrate that species that could reproduce via the auto-pollination suffered the reproductive interference and that the native species also exert the resistive reproductive interference slightly. These interactions can explain the displacement pattern of the native species by the alien congener in Japan.
文摘Present study was conducted to investigate the Cadmium (Cd) phytoextraction potential of two plants (Veronica anagallis-aquatic and Epilobium laxum Royle) for Cd removal from induced saline water. In hydroponic system, various concentrations of the Cd (50, 100, and 150 ppm) and NaCl salt (1000, 3000, and 6000 ppm) were used alone and in various combinations to evaluate the effect of salt (NaCl) concentrations on Cd absorption and accumulation in Veronica anagallis and Epilobium plants. The Cd at higher concentrations (100 and 150 ppm) significantly reduced the growth and biomass of both plants and addition of salt (NaCl) to growth media (Hoagland solution) further reduced the growth. The Cadmium (Cd) translocation factor (TF) of Epilobium plant was more than one (1), while the Veronica plant showed translocation factor less than 0.5. Veronica plant showed higher Bio-concentration factor (BCF) as more than 3.5 and Epilobium plant demonstrated Bio-concentration factor less than 1 (BCF 1 is a threshold limit for a plant to be hyper-accumulator of Cd). Conclusively, the Veronica anagallis plant is reported as Cd hyper-accumulator, while Epilobium laxum plant as non hyper-accumulator on the basis of BCF values in the present findings. Further study on Veronica and Epilobium plants is recommended.
文摘目的:研究玄参科婆婆纳属植物水蔓菁(Veronica linariifolia Pall. ex Link subsp. dilatata(Nakai et Kitagawa)Hong)中的酚性化学成分。方法:采用75%乙醇提取,运用各种色谱方法进行化学成分的分离纯化,用理化方法及波谱手段解析其化学结构。结果:分离并鉴定了14个酚性化合物,其中黄酮类7个,分别为3′,4′,5,6,7-五羟基黄酮-7-O-β-D-葡萄糖基-(1″→2′)-β-D-葡萄糖苷(Ⅰ)、4′,5,7-三羟基-3′,6-二甲氧基黄酮-7-O-β-D-葡萄糖苷(Ⅱ)、芹菜素-7-O-β-D-葡萄糖醛酸苷甲酯(Ⅲ)、芹菜素-7-O-β-D-葡萄糖醛酸苷乙酯(Ⅳ)、芹菜素-7-O-β-D-葡萄糖醛酸苷丁酯(Ⅴ)、芹菜素(Ⅵ)、木犀草素(Ⅶ);酚酸类5个,分别为香草酸(Ⅷ)、对羟基苯甲酸(Ⅸ)、原儿茶酸(Ⅹ)、原儿茶酸乙酯(Ⅺ)、异阿魏酸(Ⅻ),还分到儿茶酚(X)、大黄素(XⅣ)。结论:除化合物Ⅵ、Ⅶ外,其余均为在该植物中首次分得,其中化合物Ⅱ～Ⅴ、Ⅺ、X、X为该属植物中首次分得。
文摘目的研究轮叶婆婆纳V eron ica sibirica中二萜类成分的体外抗癌作用。方法以T J905和H eL a细胞为研究对象,采用M TT法对获得的化合物进行抗癌活性初筛并对初筛活性高的化合物进行剂量依赖性实验,测定其IC50值。结果对轮叶婆婆纳石油醚及醋酸乙酯提取物中的7个二萜类化合物:二氢丹参酮Ⅰ(Ⅰ)、丹参酮Ⅰ(Ⅱ)、丹参酮ⅡA(Ⅲ)、隐丹参酮(Ⅳ)、婆婆纳对醌A(Ⅴ)、婆婆纳对醌B(Ⅵ)、弥罗松酚(Ⅶ)进行了体外抗肿瘤活性考察,表明化合物Ⅰ和Ⅳ具有显著的抗癌活性,化合物Ⅰ对T J905及H eL a细胞生长的IC50值分别为1.038、1.816μg/mL,化合物Ⅳ对T J905及H eL a细胞生长的IC50值分别为3.637、4.391μg/mL。结论轮叶婆婆纳中的二氢丹参酮Ⅰ和隐丹参酮对T J905及H eL a细胞具有较强的生长抑制活性。
