Vigorous Endosteal Reaming across Fracture Site to Aid Union in Atypical Femur Fractures

Background: Bisphosphonate abuse is associated with atypical femur fractures, which despite different fixation methods have increased non-union, delayed union, and re-operation rates. Therefore, there is a need for a surgical technique that may enhance union in such cases. Herein we are introducing a novel technique of sequential multiple vigorous reaming across the fracture site to introduce reaming debris/endosteal bone graft around the fracture site. Materials and Methods: We present a retrospective analysis of five prospectively treated patients with atypical diaphyseal femur fracture who presented to us from January 2015 to August 2019. All the patients were followed up at regular intervals and assessed both clinically and radiologically. Results: All 5 cases operated with our technique showed union at a mean follow-up of 16 weeks (12 - 20 weeks). There were no complications reported in our study at the last mean follow-up of 25 months (12 - 51 months). Conclusion: This technique of multiple vigorous reaming at and around the fracture site provides a new paradigm in the management of AFF. The autograft around the outer cortex promotes the formation of bridging callus and results in the early union.

VIGOROUSLY CARRYING OUT FOREIGN TRADE AGENCY SYSTEM

Voices are growing louder and louder,calling for vigorously carryingout the foreign trade agency system in China’s foreign economic andtrade field.Vice Premier Li Lanqing in charge of foreign trade andeconomic cooperation has pointed out many times recently that theoperational mode of foreign trade should be transferred from thetraditional purchase system to service-type agency system.This isimportant to deepening the reform of the foreign trade system.

Jinjiang——Radiant and Vigorous

JINJIANG is a coastal city in southeast Fujian Province, across the sea from Jinmen and Taiwan. Before opening and reform, its lack of resources, undeveloped industry, large population and insufficient farming land rendered it poverty-stricken. In recent years, however, the city has undergone drastic change.In 1994 Jinjiang ranked 15th among the top 100 cities of China. Despite the impact of the Southeast Asia financial crisis and world economic recession, it has maintained

China's Economic Development is Healthy,Orderly,and Vigorous

From May 31 to June 3,Mr.Ji Bingxuan,Vice-Chairman of NPC Standing Committee and Vice-President of CAFIU visited Canada,leading a CAFIU delegation.During the visit,he attended a seminar themed"China’s Economic and Social Development"jointly hosted by the Chinese Embassy in Canada and the Canadian International Council,and delivered a keynote speech.The following is the full text of the speech.

On Developing a Vigorous Cultural Environment for Knowledge Innovation

The development of an innova-tion-oriented culture is one of thefive objectives set by the ChineseAcademy of Sciences (CAS) for itsKnowledge Innovation Program(KIP). It falls in line with the call

Vigorously Developed China's Satellite Meteorological Cause

This article describes the development of the meteorological satellite,its data applications in China and the problems in the further development of China’s satellite meteorological cause.

Industrial textiles:The market demand still remains vigorous

Favorable industrial operation In 2018,China’s industry of textile products for industrial use waded through a complex development environment,but the demand on major markets was relatively stable.Policies subsequently promulgated by the Chinese government to support development of the real economy played an increasingly important role.On the whole,the industry was enjoying a favorable development.That the production and sales steadily grew but the profit growth rate dropped would be initially curbed.

China Great Wall Industry Corporation Vigorously Developing

Founded in 1980, China Great Wall Industry Corporation (CGWIC) is a foreign economy and trade corporation which combines technology with industry and trade. The Corporation under China Aerospace Corporation, is the core of China Aerospace Great Wall Enterprises Group. It is a state-owned economic entity, mainly engaged in foreign economy, technology and trade of space scientific and technological industry. It is the only business organization with the exclusive government authorization to provide commercial launch services to foreign customers

Vigorously Boosting the Development of Chinese Human Rights Theory and Practice

We feel a great honor and heavy responsibil- ity upon the Human Rights Research Center at Shandong University being named one of China＇s national human rights education and training bases. In our view, national human rights education and training bases should keep up with the times, bring into full play their ad- vantages of uniqueness and openness, complement each other, make con- certed efforts to achieve innovation and vigorously boost the development of Chinese human rights theory and practice. The university center will continue to bring into play its tradi- tional strength in theoretical research and graduate education and work hard to fulfill all the tasks of the center. It will focus on the following work.

Natural variation in the cytochrome c oxidase subunit 5B OsCOX5B regulates seed vigor by altering energy production in rice

Seed vigor is a crucial trait for the direct seeding of rice.Here we examined the genetic regulation of seed vigor traits in rice,including germination index(GI)and germination potential(GP),using a genome-wide association study approach.One major quantitative trait locus,qGI6/qGP6,was identified simultaneously for both GI and GP.The candidate gene encoding the cytochrome c oxidase subunit 5B(OsCOX5B)was validated for qGI6/qGP6.The disruption of OsCOX5B caused the vigor traits to be significantly lower in Oscox5b mutants than in the japonica Nipponbare wild type(WT).Gene co-expression analysis revealed that OsCOX5B influences seed vigor mainly by modulating the tricarboxylic acid cycle process.The glucose levels were significantly higher while the pyruvic acid and adenosine triphosphate levels were significantly lower in Oscox5b mutants than in WT during seed germination.The elite haplotype of OsCOX5B facilitates seed vigor by increasing its expression during seed germination.Thus,we propose that OsCOX5B is a potential target for the breeding of rice varieties with enhanced seed vigor for direct seeding.

Direct-Seeded Rice: Genetic Improvement of Game-Changing Traits for Better Adaption

The sustainability of rice production continues to be a subject of uncertainty and inquiry attributed to shifts in climatic conditions. In light of the impending climate change crisis and the high labor and water costs accompanying it, direct-seeded rice(DSR) is unquestionably one of the most practical solutions. Despite its resource and climate-friendly advantages, early maturing rice faces weed competitiveness and seedling establishment challenges. Resolving these issues is crucial for promoting its wider adoption among farmers, presenting it as a more effective sustainable rice cultivation method globally. Diverse traditional and contemporary breeding methods are employed to mitigate the limitations of the DSR approach, leveraging advanced techniques such as speed breeding and genome editing. Focusing on key traits like mesocotyl length elongation, early seedling vigor, root system architecture, and weed competitiveness holds promise for transformative improvements in DSR adaptation at a broader scale within farming communities. This review aims to summarize how these features contribute to increased crop production in DSR conditions and explore the research efforts focusing on enhancing DSR adaptation through these traits. Emphasizing the pivotal role of these game-changing traits in DSR adaptation, our analysis sheds light on their potential transformative impact and offers valuable insights for advancing DSR practices.

A Multi-Level Analysis of the Effects of Epoch Length on the Estimates of Children’s Moderate to Vigorous Physical Activity

Using an ActiGraph GT3X+accelerometer,the study examined the effects of different epoch lengths on children’s moderate to vigorous physical activity(MVPA).The study also tested how different MVPA levels influence the relationship between epoch length and MVPA.The participants included third(n=28)and fourth grade(n=35)students.The third graders participated in a physical education class while the fourth graders were engaged in an active video game(AVG)class.Data were downloaded using six different epoch lengths.MVPA estimates were determined by five different cut points.Multi-level analyses were used to analyze the data.Results showed that when lower cut points were used,MVPA was positively related to epoch lengths,and this relationship was stronger when the MVPA level was higher.When higher cut points were used,epoch length was negatively related to MVPA,and this relationship was stronger when the MVPA level was lower.This study revealed that different epoch lengths generate various estimates of MVPA,and the relationship between epoch length and MVPA is affected by MVPA levels.