In order to solve the problem of real-time soft tissue torsion simulation in virtual surgeries,a torsion model based on coil spring is proposed to actualize real-time interactions and applications in virtual surgeries...In order to solve the problem of real-time soft tissue torsion simulation in virtual surgeries,a torsion model based on coil spring is proposed to actualize real-time interactions and applications in virtual surgeries. The proposed model is composed of several connected coil springs in series. The sum of torsion deformation on every coil is equivalent to the soft tissue surface deformation. The calculation of the model is simple because the method for calculating the torsion deformation for each coil spring is the same. The virtual surgery simulation system is established on PHANTOM OMNI haptic device based on the Open GL 3 D graphic interface and VC + + software,and it is used to simulate the torsion deformation of virtual legs and arms. Experimental results show that the proposed model can effectively simulate the torsion deformation of soft tissue while being of real-time performance and simplicity,which can well meet requirements of virtual operation simulations.展开更多
The broad application of virtual reality (VR) to medicine has been of great value. The virtual surgery is one of technically difficult applications. With the expansion of the increasingly fine and complicated ear micr...The broad application of virtual reality (VR) to medicine has been of great value. The virtual surgery is one of technically difficult applications. With the expansion of the increasingly fine and complicated ear microsurgery, new methods are required to train the doctors. It is necessary and of practical significance to apply VR to the ear micro-operation, which is a functional operation with high precision and great difficulties. In this article, medical VR applications were reviewed. The application of VR to the ear microsurgery was discussed and the virtual ear microsurgery system was designed.展开更多
Recently,a novel workflow known as the virtual epileptic patient(VEP)has been proposed by a research team from Aix Marseille Universitéin their papers published in Lancet Neurology,Science Translational Medicine ...Recently,a novel workflow known as the virtual epileptic patient(VEP)has been proposed by a research team from Aix Marseille Universitéin their papers published in Lancet Neurology,Science Translational Medicine and Epilepsia.This method involves creating an individualized virtual brain model based on computational modelling,which can facilitate clinical decision-making by estimating the epileptogenic zone and performing the virtual surgery.Here,we summarize brief workflow,strengths,and limitations of VEP,as well as its performance in a retrospective study of 53 patients with drug-resistant focal epilepsy who underwent stereoelectroencephalography.A large-scale clinical trial(NCT03643016)is underway to further assess VEP,which is expected to enroll 356 patients prospectively.As supporting evidence accumulates,the clinical application of VEP has the potential to improve clinical practice,leading to better outcomes and qualities of life of patients.展开更多
Telemedicine plays an important role in Corona Virus Disease 2019(COVID-19).The virtual surgery simulation system,as a key component in telemedicine,requires to compute in real-time.Therefore,this paper proposes a rea...Telemedicine plays an important role in Corona Virus Disease 2019(COVID-19).The virtual surgery simulation system,as a key component in telemedicine,requires to compute in real-time.Therefore,this paper proposes a realtime cutting model based on finite element and order reduction method,which improves the computational speed and ensure the real-time performance.The proposed model uses the finite element model to construct a deformation model of the virtual lung.Meanwhile,a model order reduction method combining proper orthogonal decomposition and Galerkin projection is employed to reduce the amount of deformation computation.In addition,the cutting path is formed according to the collision intersection position of the surgical instrument and the lesion area of the virtual lung.Then,the Bezier curve is adopted to draw the incision outline after the virtual lung has been cut.Finally,the simulation system is set up on the PHANTOM OMNI force haptic feedback device to realize the cutting simulation of the virtual lung.Experimental results show that the proposed model can enhance the real-time performance of telemedicine,reduce the complexity of the cutting simulation and make the incision smoother and more natural.展开更多
In order to solve the problem of high computing cost and low simulation accuracy caused by discontinuity of incision in traditional meshless model,this paper proposes a soft tissue deformation model based on the Marqu...In order to solve the problem of high computing cost and low simulation accuracy caused by discontinuity of incision in traditional meshless model,this paper proposes a soft tissue deformation model based on the Marquardt algorithm and enrichment function.The model is based on the element-free Galerkin method,in which Kelvin viscoelastic model and adjustment function are integrated.Marquardt algorithm is applied to fit the relation between force and displacement caused by surface deformation,and the enrichment function is applied to deal with the discontinuity in the meshless method.To verify the validity of the model,the Sensable Phantom Omni force tactile interactive device is used to simulate the deformations of stomach and heart.Experimental results show that the proposed model improves the real-time performance and accuracy of soft tissue deformation simulation,which provides a new perspective for the application of the meshless method in virtual surgery.展开更多
Background Liver resection involves surgical removal of a portion of the liver.It is used to treat liver tumors and liver injuries.The complexity and high-risk nature of this surgery prevents novice doctors from pract...Background Liver resection involves surgical removal of a portion of the liver.It is used to treat liver tumors and liver injuries.The complexity and high-risk nature of this surgery prevents novice doctors from practicing it on real patients.Virtual surgery simulation was developed to simulate surgical procedures to enable medical professionals to be trained without requiring a patient,a cadaver,or an animal.Therefore,there is a strong need for the development of a liver resection surgery simulation system.We propose a real-time simulation system that provides realistic visual and tactile feedback for hepatic parenchymal transection.Methods The tetrahedron structure and cluster-based shape matching are used for physical model construction,topology update of a three-dimensional liver model soft deformation simulation,and haptic rendering acceleration.During the liver parenchyma separation simulation,a tetrahedral mesh is used for surface triangle subdivision and surface generation of the surgical wound.The shape-matching cluster is separated via component detection on an undirected graph constructed using the tetrahedral mesh.Results In our system,cluster-based shape matching is implemented on a GPU,whereas haptic rendering and topology updates are implemented on a CPU.Experimental results show that haptic rendering can be performed at a high frequency(>900Hz),whereas mesh skinning and graphics rendering can be performed at 45fps.The topology update can be executed at an interactive rate(>10Hz)on a single CPU thread.Conclusions We propose an interactive hepatic parenchymal transection simulation method based on a tetrahedral structure.The tetrahedral mesh simultaneously supports physical model construction,topology update,and haptic rendering acceleration.展开更多
The cutting simulation of soft tissue is important in virtual surgery.It includes three major challenges in computation:Soft tissue simulation,collision detection,and handling,as well as soft tissue models.In order to...The cutting simulation of soft tissue is important in virtual surgery.It includes three major challenges in computation:Soft tissue simulation,collision detection,and handling,as well as soft tissue models.In order to address the earlier challenges,we propose a virtual cutting system based on the mass-spring model.In this system,MSM is utilized to simulate the soft tissue model.Residual stress is introduced to the model for simulating the shrinking effect of soft tissue in cutting.Second,a cylinder-based collision detection method is used to supervise the collision between surgical tools and soft tissue.Third,we simulate the cutting operation with a three-stage cutting method with swept volume,B´ezier curve,and an algorithm named shortest distance nodes matching method.In order to verify the system performance,we carry out three validation experiments on the proposed system:Cutting accuracy experiment,collision detection validation,and practical cutting evaluation.Experiments indicate that our system can well perform the shrinking effect of soft tissue in cutting.The system has fast and accurate collision detection.Moreover,the system can reconstruct smooth incisions vividly.展开更多
In the simulation of acupuncture manipulation,it is necessary to accurately capture the information of acupuncture points and particles around them.Therefore,a soft tissue modeling method that can accurately track mod...In the simulation of acupuncture manipulation,it is necessary to accurately capture the information of acupuncture points and particles around them.Therefore,a soft tissue modeling method that can accurately track model particles is needed.In this paper,a soft tissue acupuncture model based on the mass-spring force net is designed.MSM is used as the auxiliary model and the SHF model is combined.SHF is used to establish a three-layer soft tissue model of skin,fat,and muscle,and a layer of the MSM based force network is covered on the surface of soft tissue to realize the complementary advantages and disadvantages of spherical harmonic function and MSM.In addition,a springback algorithm is designed to simulate the springback phenomenon of soft tissue skin during acupuncture.The evaluation results show that the soft tissue acupuncture modeling method based on mass-spring force net can effectively simulate the springback phenomenon of soft tissue surface during acupuncture surgery,and has good comprehensive performance in the application of virtual acupuncture surgery simulation.展开更多
In order to solve the problem that the existing meshless models are of high computational complexity and are difficult to express the biomechanical characteristics of real soft tissue, a local high-resolution deformat...In order to solve the problem that the existing meshless models are of high computational complexity and are difficult to express the biomechanical characteristics of real soft tissue, a local high-resolution deformation model of soft tissue based on element-free Galerkin method is proposed. The proposed model applies an element-free Galerkin method to establish the model, and integrates Kelvin viscoelastic model and adjustment function to simulate nonlinear viscoelasticity of soft tissue. Meanwhile, a local high-resolution algorithm is applied to sample and render the deformed region of the model to reduce the computational complexity. To verify the effectiveness of the model,liver and brain tumor deformation simulation experiments are carried out. The experimental results show that compared with the existing meshless models, the proposed model well reflects the biomechanical characteristics of soft tissue, and is of high authenticity, which can provide better visual feedback to users while reducing computational cost.展开更多
The objective of this study was to expound a novel surgical management technique assisted by patient-specific implants(PSIs)for comminuted fractures of the zygomaticomaxillary complex(ZMC).The aim of this study was to...The objective of this study was to expound a novel surgical management technique assisted by patient-specific implants(PSIs)for comminuted fractures of the zygomaticomaxillary complex(ZMC).The aim of this study was to explore the feasibility of using PSIs to accurately restore and fix comminuted fractures.A male patient with an old ZMC comminuted fracture was used to describe the workflow,technique,and method.Computerassisted surgical simulation was used to determine the optimal plan for the reduction of bone segments prior to surgery.The PSIs were used to accurately guide the surgeon’s position of the bone segments,as planned,during the operation.Oral panoramic films and cephalometric films were taken immediately at 1,3,6,and 12 months after the operation,while computed tomography images of the whole skull were taken immediately,half a year,and one year after the operation.The patient’s follow-up showed that the zygomatic symmetry recovered well post-surgery and the patient was satisfied with the outcome.This new surgical method greatly improved the facial symmetry of this patient.展开更多
Laparoscopic cholecystectomy is used to treat cholecystitis and cholelithiasis.Because the high risk of the surgery prevents novice doctors from practicing it on real patients,VR-based surgical simulation has been dev...Laparoscopic cholecystectomy is used to treat cholecystitis and cholelithiasis.Because the high risk of the surgery prevents novice doctors from practicing it on real patients,VR-based surgical simulation has been developed to simulate surgical procedures to train surgeons without patients,cadavers,or animals.In this study,we propose a real-time system designed to provide plausible visual and tactile simulation of the main surgical procedures.To achieve this,the physical properties of organs are modeled by particles,and cluster-based shape matching is used to simulate soft deformation.The haptic interaction between tools and soft tissue is modeled as a collision between a capsule and particles.Constraint-based haptic rendering is used to generate feedback force and the non-penetrating position of the virtual tool.The proposed system can simulate the major steps of laparoscopic cholecystectomy,such as the anatomy of Calot’s triangle,clipping of the cystic duct and biliary artery,disjunction of the cystic duct and biliary artery,and separation of the gallbladder bed.The experimental results show that haptic rendering can be performed at a high frequency(>900 Hz),whereas mesh skinning and graphics rendering can be performed at 60 frames per second(fps).展开更多
基金Supported by the National Natural Science Foundation of China(No.61502240,61502096,61304205,61773219)the Natural Science Foundation of Jiangsu Province(No.BK20141002,BK20150634)
文摘In order to solve the problem of real-time soft tissue torsion simulation in virtual surgeries,a torsion model based on coil spring is proposed to actualize real-time interactions and applications in virtual surgeries. The proposed model is composed of several connected coil springs in series. The sum of torsion deformation on every coil is equivalent to the soft tissue surface deformation. The calculation of the model is simple because the method for calculating the torsion deformation for each coil spring is the same. The virtual surgery simulation system is established on PHANTOM OMNI haptic device based on the Open GL 3 D graphic interface and VC + + software,and it is used to simulate the torsion deformation of virtual legs and arms. Experimental results show that the proposed model can effectively simulate the torsion deformation of soft tissue while being of real-time performance and simplicity,which can well meet requirements of virtual operation simulations.
基金The Scientific Research Fund of ShanghaiScience Committee( 0 3 411980 8) and the Science and TechnologySpecial Fund of Pudong New District( PKJ2 0 0 3 -4 1)
文摘The broad application of virtual reality (VR) to medicine has been of great value. The virtual surgery is one of technically difficult applications. With the expansion of the increasingly fine and complicated ear microsurgery, new methods are required to train the doctors. It is necessary and of practical significance to apply VR to the ear micro-operation, which is a functional operation with high precision and great difficulties. In this article, medical VR applications were reviewed. The application of VR to the ear microsurgery was discussed and the virtual ear microsurgery system was designed.
基金This work was supported by the National Key R&D Program of China(No.2022YFC2503800)the National Natural Science Foundation of China(No.82071454)Beijing Municipal Science&Technology Commission(No.Z211100002921032).
文摘Recently,a novel workflow known as the virtual epileptic patient(VEP)has been proposed by a research team from Aix Marseille Universitéin their papers published in Lancet Neurology,Science Translational Medicine and Epilepsia.This method involves creating an individualized virtual brain model based on computational modelling,which can facilitate clinical decision-making by estimating the epileptogenic zone and performing the virtual surgery.Here,we summarize brief workflow,strengths,and limitations of VEP,as well as its performance in a retrospective study of 53 patients with drug-resistant focal epilepsy who underwent stereoelectroencephalography.A large-scale clinical trial(NCT03643016)is underway to further assess VEP,which is expected to enroll 356 patients prospectively.As supporting evidence accumulates,the clinical application of VEP has the potential to improve clinical practice,leading to better outcomes and qualities of life of patients.
基金supported,in part,by the Natural Science Foundation of Jiangsu Province under Grant Numbers BK20201136,BK20191401in part,by the National Nature Science Foundation of China under Grant Numbers 61502240,61502096,61304205,61773219in part,by the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)fund.
文摘Telemedicine plays an important role in Corona Virus Disease 2019(COVID-19).The virtual surgery simulation system,as a key component in telemedicine,requires to compute in real-time.Therefore,this paper proposes a realtime cutting model based on finite element and order reduction method,which improves the computational speed and ensure the real-time performance.The proposed model uses the finite element model to construct a deformation model of the virtual lung.Meanwhile,a model order reduction method combining proper orthogonal decomposition and Galerkin projection is employed to reduce the amount of deformation computation.In addition,the cutting path is formed according to the collision intersection position of the surgical instrument and the lesion area of the virtual lung.Then,the Bezier curve is adopted to draw the incision outline after the virtual lung has been cut.Finally,the simulation system is set up on the PHANTOM OMNI force haptic feedback device to realize the cutting simulation of the virtual lung.Experimental results show that the proposed model can enhance the real-time performance of telemedicine,reduce the complexity of the cutting simulation and make the incision smoother and more natural.
基金This work was supported,in part,by the National Nature Science Foundation of China under grant numbers 61502240,61502096,61304205,61773219in part,by the Natural Science Foundation of Jiangsu Province under grant number BK20191401+1 种基金in part,by the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)fundin part,by the Collaborative Innovation Center of Atmospheric Environment and Equipment Technology(CICAEET)fund.
文摘In order to solve the problem of high computing cost and low simulation accuracy caused by discontinuity of incision in traditional meshless model,this paper proposes a soft tissue deformation model based on the Marquardt algorithm and enrichment function.The model is based on the element-free Galerkin method,in which Kelvin viscoelastic model and adjustment function are integrated.Marquardt algorithm is applied to fit the relation between force and displacement caused by surface deformation,and the enrichment function is applied to deal with the discontinuity in the meshless method.To verify the validity of the model,the Sensable Phantom Omni force tactile interactive device is used to simulate the deformations of stomach and heart.Experimental results show that the proposed model improves the real-time performance and accuracy of soft tissue deformation simulation,which provides a new perspective for the application of the meshless method in virtual surgery.
基金NSFC(61902014)Research Unit of Virtual Human and Virtual Surgery,Chinese Academy of Medical Sciences(2019RU004)Medical Innovation Research Project of PLA General Hospital(CX19032).
文摘Background Liver resection involves surgical removal of a portion of the liver.It is used to treat liver tumors and liver injuries.The complexity and high-risk nature of this surgery prevents novice doctors from practicing it on real patients.Virtual surgery simulation was developed to simulate surgical procedures to enable medical professionals to be trained without requiring a patient,a cadaver,or an animal.Therefore,there is a strong need for the development of a liver resection surgery simulation system.We propose a real-time simulation system that provides realistic visual and tactile feedback for hepatic parenchymal transection.Methods The tetrahedron structure and cluster-based shape matching are used for physical model construction,topology update of a three-dimensional liver model soft deformation simulation,and haptic rendering acceleration.During the liver parenchyma separation simulation,a tetrahedral mesh is used for surface triangle subdivision and surface generation of the surgical wound.The shape-matching cluster is separated via component detection on an undirected graph constructed using the tetrahedral mesh.Results In our system,cluster-based shape matching is implemented on a GPU,whereas haptic rendering and topology updates are implemented on a CPU.Experimental results show that haptic rendering can be performed at a high frequency(>900Hz),whereas mesh skinning and graphics rendering can be performed at 45fps.The topology update can be executed at an interactive rate(>10Hz)on a single CPU thread.Conclusions We propose an interactive hepatic parenchymal transection simulation method based on a tetrahedral structure.The tetrahedral mesh simultaneously supports physical model construction,topology update,and haptic rendering acceleration.
基金This work was supported,in part,by the National Nature Science Foundation of China under Grant Nos.61502240,61502096,61304205,61773219in part,by the Natural Science Foundation of Jiangsu Province under Grant Nos.BK20191401 and BK20201136+2 种基金in part,by the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)fundin part,by the Collaborative Innovation Center of Atmospheric Environment and Equipment Technology(CICAEET)fundNUIST Students’Platform for Innovation and Entrepreneurship Training Program.
文摘The cutting simulation of soft tissue is important in virtual surgery.It includes three major challenges in computation:Soft tissue simulation,collision detection,and handling,as well as soft tissue models.In order to address the earlier challenges,we propose a virtual cutting system based on the mass-spring model.In this system,MSM is utilized to simulate the soft tissue model.Residual stress is introduced to the model for simulating the shrinking effect of soft tissue in cutting.Second,a cylinder-based collision detection method is used to supervise the collision between surgical tools and soft tissue.Third,we simulate the cutting operation with a three-stage cutting method with swept volume,B´ezier curve,and an algorithm named shortest distance nodes matching method.In order to verify the system performance,we carry out three validation experiments on the proposed system:Cutting accuracy experiment,collision detection validation,and practical cutting evaluation.Experiments indicate that our system can well perform the shrinking effect of soft tissue in cutting.The system has fast and accurate collision detection.Moreover,the system can reconstruct smooth incisions vividly.
基金This work was supported,in part,by the National Nature Science Foundation of China under Grant Numbers 61773219in part,by the Natural Science Foundation of Jiangsu Province under Grant Number BK20201136,BK20191401+2 种基金in part,by the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)fundin part,by the Collaborative Innovation Center of Atmospheric Environment and Equipment Technology(CICAEET)fundNUIST Students’Platform for Innovation and Entrepreneurship Training Program.
文摘In the simulation of acupuncture manipulation,it is necessary to accurately capture the information of acupuncture points and particles around them.Therefore,a soft tissue modeling method that can accurately track model particles is needed.In this paper,a soft tissue acupuncture model based on the mass-spring force net is designed.MSM is used as the auxiliary model and the SHF model is combined.SHF is used to establish a three-layer soft tissue model of skin,fat,and muscle,and a layer of the MSM based force network is covered on the surface of soft tissue to realize the complementary advantages and disadvantages of spherical harmonic function and MSM.In addition,a springback algorithm is designed to simulate the springback phenomenon of soft tissue skin during acupuncture.The evaluation results show that the soft tissue acupuncture modeling method based on mass-spring force net can effectively simulate the springback phenomenon of soft tissue surface during acupuncture surgery,and has good comprehensive performance in the application of virtual acupuncture surgery simulation.
基金Supported by the National Natural Science Foundation of China(No.61502240,61502096,61304205,61773219)Natural Science Foundation of Jiangsu Province(No.BK20141002,BK20150634)
文摘In order to solve the problem that the existing meshless models are of high computational complexity and are difficult to express the biomechanical characteristics of real soft tissue, a local high-resolution deformation model of soft tissue based on element-free Galerkin method is proposed. The proposed model applies an element-free Galerkin method to establish the model, and integrates Kelvin viscoelastic model and adjustment function to simulate nonlinear viscoelasticity of soft tissue. Meanwhile, a local high-resolution algorithm is applied to sample and render the deformed region of the model to reduce the computational complexity. To verify the effectiveness of the model,liver and brain tumor deformation simulation experiments are carried out. The experimental results show that compared with the existing meshless models, the proposed model well reflects the biomechanical characteristics of soft tissue, and is of high authenticity, which can provide better visual feedback to users while reducing computational cost.
文摘The objective of this study was to expound a novel surgical management technique assisted by patient-specific implants(PSIs)for comminuted fractures of the zygomaticomaxillary complex(ZMC).The aim of this study was to explore the feasibility of using PSIs to accurately restore and fix comminuted fractures.A male patient with an old ZMC comminuted fracture was used to describe the workflow,technique,and method.Computerassisted surgical simulation was used to determine the optimal plan for the reduction of bone segments prior to surgery.The PSIs were used to accurately guide the surgeon’s position of the bone segments,as planned,during the operation.Oral panoramic films and cephalometric films were taken immediately at 1,3,6,and 12 months after the operation,while computed tomography images of the whole skull were taken immediately,half a year,and one year after the operation.The patient’s follow-up showed that the zygomatic symmetry recovered well post-surgery and the patient was satisfied with the outcome.This new surgical method greatly improved the facial symmetry of this patient.
基金This work was supported in part by the National Natural Science Foundation of China(No.61902014)Beijing Natural Science Foundation(No.4214066)Beijing Advanced Innovation Center for Biomedical Engineering(No.ZF138G1714).
文摘Laparoscopic cholecystectomy is used to treat cholecystitis and cholelithiasis.Because the high risk of the surgery prevents novice doctors from practicing it on real patients,VR-based surgical simulation has been developed to simulate surgical procedures to train surgeons without patients,cadavers,or animals.In this study,we propose a real-time system designed to provide plausible visual and tactile simulation of the main surgical procedures.To achieve this,the physical properties of organs are modeled by particles,and cluster-based shape matching is used to simulate soft deformation.The haptic interaction between tools and soft tissue is modeled as a collision between a capsule and particles.Constraint-based haptic rendering is used to generate feedback force and the non-penetrating position of the virtual tool.The proposed system can simulate the major steps of laparoscopic cholecystectomy,such as the anatomy of Calot’s triangle,clipping of the cystic duct and biliary artery,disjunction of the cystic duct and biliary artery,and separation of the gallbladder bed.The experimental results show that haptic rendering can be performed at a high frequency(>900 Hz),whereas mesh skinning and graphics rendering can be performed at 60 frames per second(fps).