It is well known that auditory cortical areas are activated by visual stimulation in the deaf. However, it is not known whether the information enters from the primary visual area or high-level visual areas. In this s...It is well known that auditory cortical areas are activated by visual stimulation in the deaf. However, it is not known whether the information enters from the primary visual area or high-level visual areas. In this study, we used visual language stimulation to examine visual-auditory functional connectivity. For this, we used functional magnetic resonance imaging (fMRI) in a congenitally deaf subject to localize areas in the auditory cortex that showed cross-modal reorganization for the processing of visual language inputs and estimate areas in the visual ventral stream, from which language signal inputs enter the auditory areas in the congenitally deaf. We found that the anterior region of the secondary auditory cortex in the superior temporal gyrus showed language-specific activation and that the visual inputs into the area were from the fusiform gyrus, which is a high-level visual area.展开更多
BACKGROUND： The role of the left midfusiform gyrus as a target for visual word processing has been a topic of discussion. Numerous studies have utilized alphabetic writing for subject matter. However, few have addres...BACKGROUND： The role of the left midfusiform gyrus as a target for visual word processing has been a topic of discussion. Numerous studies have utilized alphabetic writing for subject matter. However, few have addressed visual processing of Chinese characters in the left midfusiform gyrus. OBJECTIVE： To verify visual processing of Chinese characters and images in the left midfusiform gyrus using functional magnetic resonance imaging. DESIGN, TIME AND SETTING： A blocked design paradigm study. Experiments were performed at the Room of Magnetic Resonance, Guangdong Provincial Second People＇s Hospital, China from May to June 2009. PARTICIPANTS： A total of eight undergraduate students were recruited from Guangzhou University of China, comprising two females and six males, aged 20-23 years. The subjects were right-handed which was determined by a Chinese standard questionnaire. None of the subjects had a history of psychoneurosis, familial disease, color blindness, or color weakness. METHODS： A total of eight undergraduates were enrolled as subjects. Picture-naming and verb generation tasks were employed through the use of functional magnetic resonance imaging. Analysis of Functional Neurolmages software was used to process the data. MAIN OUTCOME MEASURES： Visual processing of Chinese characters and images in the left midfusiform gyrus was measured. RESULTS： Picture-naming and verb generation tasks were shown to significantly activate the bilateral midfusiform gyrus. Activation occurred in the visual word form area of the left midfusiform gyrus. CONCLUSION： The left midfusiform gyrus plays a general role in visual processing of Chinese characters and images.展开更多
文摘It is well known that auditory cortical areas are activated by visual stimulation in the deaf. However, it is not known whether the information enters from the primary visual area or high-level visual areas. In this study, we used visual language stimulation to examine visual-auditory functional connectivity. For this, we used functional magnetic resonance imaging (fMRI) in a congenitally deaf subject to localize areas in the auditory cortex that showed cross-modal reorganization for the processing of visual language inputs and estimate areas in the visual ventral stream, from which language signal inputs enter the auditory areas in the congenitally deaf. We found that the anterior region of the secondary auditory cortex in the superior temporal gyrus showed language-specific activation and that the visual inputs into the area were from the fusiform gyrus, which is a high-level visual area.
基金the Key Programming Research Project of Education Science During the 11~(th) Five-Year Plan Period of Guangdong Province, No. 06TJZ014the Programming Project of Education Science During the 11~(th) Five-Year Plan Period of Guangzhou City, No. 07B290
文摘BACKGROUND： The role of the left midfusiform gyrus as a target for visual word processing has been a topic of discussion. Numerous studies have utilized alphabetic writing for subject matter. However, few have addressed visual processing of Chinese characters in the left midfusiform gyrus. OBJECTIVE： To verify visual processing of Chinese characters and images in the left midfusiform gyrus using functional magnetic resonance imaging. DESIGN, TIME AND SETTING： A blocked design paradigm study. Experiments were performed at the Room of Magnetic Resonance, Guangdong Provincial Second People＇s Hospital, China from May to June 2009. PARTICIPANTS： A total of eight undergraduate students were recruited from Guangzhou University of China, comprising two females and six males, aged 20-23 years. The subjects were right-handed which was determined by a Chinese standard questionnaire. None of the subjects had a history of psychoneurosis, familial disease, color blindness, or color weakness. METHODS： A total of eight undergraduates were enrolled as subjects. Picture-naming and verb generation tasks were employed through the use of functional magnetic resonance imaging. Analysis of Functional Neurolmages software was used to process the data. MAIN OUTCOME MEASURES： Visual processing of Chinese characters and images in the left midfusiform gyrus was measured. RESULTS： Picture-naming and verb generation tasks were shown to significantly activate the bilateral midfusiform gyrus. Activation occurred in the visual word form area of the left midfusiform gyrus. CONCLUSION： The left midfusiform gyrus plays a general role in visual processing of Chinese characters and images.
