目的探讨WASP家族富含脯氨酸同源蛋白1(WASP-family verprolin-homologous protein 1,WAVE1)及基质金属蛋白酶-2(matrix metalloproteinases-2,MMP-2)和基质金属蛋白酶-9(MMP-9)在卵巢癌的表达及临床意义。方法采用免疫组化SABC三步法检...目的探讨WASP家族富含脯氨酸同源蛋白1(WASP-family verprolin-homologous protein 1,WAVE1)及基质金属蛋白酶-2(matrix metalloproteinases-2,MMP-2)和基质金属蛋白酶-9(MMP-9)在卵巢癌的表达及临床意义。方法采用免疫组化SABC三步法检测47例卵巢癌、30例卵巢良性肿瘤和21例正常卵巢组织中WAVE1、MMP-2、MMP-9的表达,并对卵巢癌组织WAVE1与MMP-2、MMP-9的表达进行相关性分析。结果①WAVE1、MMP-2及MMP-9在卵巢癌中的表达均高于在正常卵巢组织及卵巢良性组织中的表达,差异有统计学意义(P<0.05);Spearman相关分析显示,WAVE1和MMP-2、MMP-9两两表达成正相关(r=0.773,r=0.664,P<0.05)。②WAVE1的表达与卵巢癌的临床分期、组织分化及Ca-125水平有关(P<0.05),与年龄、肿瘤的直径无关(P>0.05)。MMP-2、MMP-9表达与卵巢癌的临床分期有关(P<0.05),与年龄、组织分化、Ca-125水平及肿瘤直径无关(P>0.05)。结论 WAVE1和MMP-2、MMP-9在卵巢癌中呈现高表达,早期联合筛查WAVE1和MMP-2、MMP-9指标对卵巢癌病情演变和预后评估有着重要的临床意义。展开更多
Two(3+1)-dimensional shallow water wave equations are studied by using residual symmetry and the consistent Riccati expansion(CRE) method. Through localization of residual symmetries, symmetry reduction solutions of t...Two(3+1)-dimensional shallow water wave equations are studied by using residual symmetry and the consistent Riccati expansion(CRE) method. Through localization of residual symmetries, symmetry reduction solutions of the two equations are obtained. The CRE method is applied to the two equations to obtain new B?cklund transformations from which a type of interesting interaction solution between solitons and periodic waves is generated.展开更多
A correlation analysis is performed to investigate the relationship between El Nino-Southern Oscillation （ENSO） and the Antarctic oscillation （AAO） at the quasi-quadrennial （QQ） timescale.It is found that the co...A correlation analysis is performed to investigate the relationship between El Nino-Southern Oscillation （ENSO） and the Antarctic oscillation （AAO） at the quasi-quadrennial （QQ） timescale.It is found that the cold tongue index （CTI） and the AAO index （AAOI） are negatively correlated with about a 7-month lead-time,while they are positively correlated with about a 15-month lag-time.To further explore this relationship,complex empirical orthogonal function analysis is employed in the QQ sea level pressure （SLP） anomalies from 1951 to 2002.The results indicate that,during the ENSO cycle,there exists one kind of global tropical wave of wavenumber 1 （GTW1） propagating eastward.With the traveling of GTW1,the tropical SLP anomaly tends to intrude into the southern mid-latitudes.Accordingly,three strong signals travel synchronously along the circumSouth-Pacific path,and a relatively weak signal extends eastward and poleward over the South Ocean in the Atlantic-Indian Ocean sector.Following the propagation of these signals,the AAO phase tends to be reversed progressively.As a result,there exists an evident lead-lag correlation between CTI and AAOI.It can be concluded that ENSO plays a key role in the phase transition of AAO at the QQ timescale.It is also noticed that this regular relationship is only evident in the canonical ENSO events,for which sea surface temperature （SST） anomalies extend westward from the tropical eastern Pacific.On the other hand,the similar relationships are not found among those atypical ENSO events for which SST anomalies spread eastward from the central Pacific,such as the 1982-1983 ENSO event.展开更多
The purpose is to study the accuracy of ocean wave parameters retrieved from C-band VV-polarization Sentinel-1Synthetic Aperture Radar（SAR） images, including both significant wave height（SWH） and mean wave period...The purpose is to study the accuracy of ocean wave parameters retrieved from C-band VV-polarization Sentinel-1Synthetic Aperture Radar（SAR） images, including both significant wave height（SWH） and mean wave period（MWP）, which are both calculated from a SAR-derived wave spectrum. The wind direction from in situ buoys is used and then the wind speed is retrieved by using a new C-band geophysical model function（GMF） model,denoted as C-SARMOD. Continuously, an algorithm parameterized first-guess spectra method（PFSM） is employed to retrieve the SWH and the MWP by using the SAR-derived wind speed. Forty-five VV-polarization Sentinel-1 SAR images are collected, which cover the in situ buoys around US coastal waters. A total of 52 subscenes are selected from those images. The retrieval results are compared with the measurements from in situ buoys. The comparison performs good for a wind retrieval, showing a 1.6 m/s standard deviation（STD） of the wind speed, while a 0.54 m STD of the SWH and a 2.14 s STD of the MWP are exhibited with an acceptable error.Additional 50 images taken in China＇s seas were also implemented by using the algorithm PFSM, showing a 0.67 m STD of the SWH and a 2.21 s STD of the MWP compared with European Centre for Medium-range Weather Forecasts（ECMWF） reanalysis grids wave data. The results indicate that the algorithm PFSM works for the wave retrieval from VV-polarization Sentinel-1 SAR image through SAR-derived wind speed by using the new GMF C-SARMOD.展开更多
A complete discrimination system for the fourth order polynomial is given. As an application, we have reduced a （1＋1）-dimensional dispersive long wave equation with general coefficients to an elementary integral fo...A complete discrimination system for the fourth order polynomial is given. As an application, we have reduced a （1＋1）-dimensional dispersive long wave equation with general coefficients to an elementary integral form and obtained its all possible exact travelling wave solutions including rational function type solutions, solitary wave solutions, triangle function type periodic solutions and Jacobian elliptic functions double periodic solutions. This method can be also applied to many other similar problems.展开更多
In this paper, we make use of the auxiliary equation and the expanded mapping methods to find the new exact periodic solutions for （2＋1）-dimensional dispersive long wave equations in mathematical physics, which are...In this paper, we make use of the auxiliary equation and the expanded mapping methods to find the new exact periodic solutions for （2＋1）-dimensional dispersive long wave equations in mathematical physics, which are expressed by Jacobi elliptic functions, and obtain some new solitary wave solutions （m → 1）. This method can also be used to explore new periodic wave solutions for other nonlinear evolution equations.展开更多
Recently, a new （2＋1）-dimensional shallow water wave system, the （2＋1）-dlmenslonal displacement shallow water wave system （2DDSWWS）, was constructed by applying the variational principle of the analytic mechan...Recently, a new （2＋1）-dimensional shallow water wave system, the （2＋1）-dlmenslonal displacement shallow water wave system （2DDSWWS）, was constructed by applying the variational principle of the analytic mechanics in the Lagrange coordinates. The disadvantage is that fluid viscidity is not considered in the 2DDSWWS, which is the same as the famous Kadomtsev-Petviashvili equation and Korteweg-de Vries equation. Applying dimensional analysis, we modify the 2DDSWWS and add the term related to the fluid viscidity to the 2DDSWWS. The approximate similarity solutions of the modified 2DDSWWS （M2DDSWWS） is studied and four similarity solutions are obtained. For the perfect fluids, the coefficient of kinematic viscosity is zero, then the M2DDSWWS will degenerate to the 2DDSWWS.展开更多
By means of variable separation approach, quite a general excitation of the new (2 + 1)-dimensional long dispersive wave system: is derived. Some types of the usual localized excitations such as dromions, lumps, ring...By means of variable separation approach, quite a general excitation of the new (2 + 1)-dimensional long dispersive wave system: is derived. Some types of the usual localized excitations such as dromions, lumps, rings, and oscillating soliton excitations can be easily constructed by selecting the arbitrary functions appropriately. Besides these usual localized structures, some new localized excitations like fractal-dromion, fractal-lump, and multi-peakon excitations of this new system are found by selecting appropriate functions.展开更多
The determining equations for the nonclassical symmetry reductions of nonlinear partial differential equations with arbitrary order can be obtained by requiring the compatibility between the original equations and the...The determining equations for the nonclassical symmetry reductions of nonlinear partial differential equations with arbitrary order can be obtained by requiring the compatibility between the original equations and the invariant surface conditions. The （2＋1）-dimensional shallow water wave equation, Boussinesq equation, and the dispersive wave equations in shallow water serve as examples i11ustrating how compatibility leads quickly and easily to the determining equations for their nonclassical symmetries.展开更多
基金Project supported by the National Natural Science Foundation of China (Grant Nos. 11975156 and 12175148)。
文摘Two(3+1)-dimensional shallow water wave equations are studied by using residual symmetry and the consistent Riccati expansion(CRE) method. Through localization of residual symmetries, symmetry reduction solutions of the two equations are obtained. The CRE method is applied to the two equations to obtain new B?cklund transformations from which a type of interesting interaction solution between solitons and periodic waves is generated.
基金The Major National Scientific Research Project on Global Change under contract No.2010CB951901the National Science Foundation of China under contract No.40821092Special Fund for Public Welfare Industry (Meteorology) under contract No.GYHY200906018
文摘A correlation analysis is performed to investigate the relationship between El Nino-Southern Oscillation （ENSO） and the Antarctic oscillation （AAO） at the quasi-quadrennial （QQ） timescale.It is found that the cold tongue index （CTI） and the AAO index （AAOI） are negatively correlated with about a 7-month lead-time,while they are positively correlated with about a 15-month lag-time.To further explore this relationship,complex empirical orthogonal function analysis is employed in the QQ sea level pressure （SLP） anomalies from 1951 to 2002.The results indicate that,during the ENSO cycle,there exists one kind of global tropical wave of wavenumber 1 （GTW1） propagating eastward.With the traveling of GTW1,the tropical SLP anomaly tends to intrude into the southern mid-latitudes.Accordingly,three strong signals travel synchronously along the circumSouth-Pacific path,and a relatively weak signal extends eastward and poleward over the South Ocean in the Atlantic-Indian Ocean sector.Following the propagation of these signals,the AAO phase tends to be reversed progressively.As a result,there exists an evident lead-lag correlation between CTI and AAOI.It can be concluded that ENSO plays a key role in the phase transition of AAO at the QQ timescale.It is also noticed that this regular relationship is only evident in the canonical ENSO events,for which sea surface temperature （SST） anomalies extend westward from the tropical eastern Pacific.On the other hand,the similar relationships are not found among those atypical ENSO events for which SST anomalies spread eastward from the central Pacific,such as the 1982-1983 ENSO event.
基金The Public Welfare Technical Applied Research Project of Zhejiang Province of China under contract No.2015C31021the National Key Research and Development Program of China under contract No.2016YFC1401605the Scientific Foundation of Zhejiang Ocean University of China
文摘The purpose is to study the accuracy of ocean wave parameters retrieved from C-band VV-polarization Sentinel-1Synthetic Aperture Radar（SAR） images, including both significant wave height（SWH） and mean wave period（MWP）, which are both calculated from a SAR-derived wave spectrum. The wind direction from in situ buoys is used and then the wind speed is retrieved by using a new C-band geophysical model function（GMF） model,denoted as C-SARMOD. Continuously, an algorithm parameterized first-guess spectra method（PFSM） is employed to retrieve the SWH and the MWP by using the SAR-derived wind speed. Forty-five VV-polarization Sentinel-1 SAR images are collected, which cover the in situ buoys around US coastal waters. A total of 52 subscenes are selected from those images. The retrieval results are compared with the measurements from in situ buoys. The comparison performs good for a wind retrieval, showing a 1.6 m/s standard deviation（STD） of the wind speed, while a 0.54 m STD of the SWH and a 2.14 s STD of the MWP are exhibited with an acceptable error.Additional 50 images taken in China＇s seas were also implemented by using the algorithm PFSM, showing a 0.67 m STD of the SWH and a 2.21 s STD of the MWP compared with European Centre for Medium-range Weather Forecasts（ECMWF） reanalysis grids wave data. The results indicate that the algorithm PFSM works for the wave retrieval from VV-polarization Sentinel-1 SAR image through SAR-derived wind speed by using the new GMF C-SARMOD.
文摘A complete discrimination system for the fourth order polynomial is given. As an application, we have reduced a （1＋1）-dimensional dispersive long wave equation with general coefficients to an elementary integral form and obtained its all possible exact travelling wave solutions including rational function type solutions, solitary wave solutions, triangle function type periodic solutions and Jacobian elliptic functions double periodic solutions. This method can be also applied to many other similar problems.
基金Project supported by the Anhui Key Laboratory of Information Materials and Devices (Anhui University),China
文摘In this paper, we make use of the auxiliary equation and the expanded mapping methods to find the new exact periodic solutions for （2＋1）-dimensional dispersive long wave equations in mathematical physics, which are expressed by Jacobi elliptic functions, and obtain some new solitary wave solutions （m → 1）. This method can also be used to explore new periodic wave solutions for other nonlinear evolution equations.
基金Project supported by the Natural Science Foundation of Guangdong Province of China (Grant No.10452840301004616)the National Natural Science Foundation of China (Grant No.61001018)the Scientific Research Foundation for the Doctors of University of Electronic Science and Technology of China Zhongshan Institute (Grant No.408YKQ09)
文摘Recently, a new （2＋1）-dimensional shallow water wave system, the （2＋1）-dlmenslonal displacement shallow water wave system （2DDSWWS）, was constructed by applying the variational principle of the analytic mechanics in the Lagrange coordinates. The disadvantage is that fluid viscidity is not considered in the 2DDSWWS, which is the same as the famous Kadomtsev-Petviashvili equation and Korteweg-de Vries equation. Applying dimensional analysis, we modify the 2DDSWWS and add the term related to the fluid viscidity to the 2DDSWWS. The approximate similarity solutions of the modified 2DDSWWS （M2DDSWWS） is studied and four similarity solutions are obtained. For the perfect fluids, the coefficient of kinematic viscosity is zero, then the M2DDSWWS will degenerate to the 2DDSWWS.
文摘By means of variable separation approach, quite a general excitation of the new (2 + 1)-dimensional long dispersive wave system: is derived. Some types of the usual localized excitations such as dromions, lumps, rings, and oscillating soliton excitations can be easily constructed by selecting the arbitrary functions appropriately. Besides these usual localized structures, some new localized excitations like fractal-dromion, fractal-lump, and multi-peakon excitations of this new system are found by selecting appropriate functions.
文摘The determining equations for the nonclassical symmetry reductions of nonlinear partial differential equations with arbitrary order can be obtained by requiring the compatibility between the original equations and the invariant surface conditions. The （2＋1）-dimensional shallow water wave equation, Boussinesq equation, and the dispersive wave equations in shallow water serve as examples i11ustrating how compatibility leads quickly and easily to the determining equations for their nonclassical symmetries.
