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植物乳杆菌WLPL01艾草发酵液干预鼠伤寒沙门氏菌感染小鼠的作用 被引量:6
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作者 詹晖 田林林 +5 位作者 钟常城 何瑶 王谦慧 杨琴 魏华 陶雪莹 《南昌大学学报(理科版)》 CAS 北大核心 2019年第4期351-358,共8页
研究了植物乳杆菌WLPL01艾草发酵液对鼠伤寒沙门氏菌感染小鼠的影响。通过构建鼠伤寒沙门氏菌感染小鼠模型,采用低剂量(5 mg·mL^-1)、中剂量(15 mg·mL^-1)和高剂量(50 mg·mL^-1)的艾草发酵液以及植物乳杆菌WLPL01菌悬液... 研究了植物乳杆菌WLPL01艾草发酵液对鼠伤寒沙门氏菌感染小鼠的影响。通过构建鼠伤寒沙门氏菌感染小鼠模型,采用低剂量(5 mg·mL^-1)、中剂量(15 mg·mL^-1)和高剂量(50 mg·mL^-1)的艾草发酵液以及植物乳杆菌WLPL01菌悬液进行干预,监测小鼠体重、各组织中鼠伤寒沙门氏菌数量、结肠和回肠的H&E染色以及相关炎症因子的表达和分泌,探究了艾草发酵液对鼠伤寒沙门氏菌感染小鼠的干预作用。结果表明,通过高剂量(50 mg·mL^-1)和中剂量(15 mg·mL^-1)艾草发酵液的干预,能有效缓解由鼠伤寒沙门氏菌感染引起的体重下降,减少肝脏、脾脏和肠系膜淋巴结中的鼠伤寒沙门氏菌的数量;并通过下调结肠和回肠中相关炎症因子(TNF-α,IFN-γ和IL-10)的转录水平及血清中TNF-α和IFN-γ的分泌量,减轻结肠、回肠的炎症及肠道损伤。 展开更多
关键词 植物乳杆菌wlpl01 艾草发酵液 鼠伤寒沙门氏菌 感染 炎症
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Effects of Lactiplantibacillus plantarum WLPL01 fermentation on antioxidant activities,bioactive compounds,and flavor profile of Artemisia argyi
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作者 Hui Zhan Wenfeng Xu +4 位作者 Xiangxiang Zhao Linlin Tian Fen Zhang Hua Wei Xueying Tao 《Food Bioscience》 SCIE 2022年第5期616-625,共10页
Artemisia argyi is a traditional Chinese food and medicine which can improve multiple diseases such as asthma and gastrointestinal disorders.However,whether the beneficial bioactivities are associated with microbial f... Artemisia argyi is a traditional Chinese food and medicine which can improve multiple diseases such as asthma and gastrointestinal disorders.However,whether the beneficial bioactivities are associated with microbial fermentation remain unknown.The objective of this study was to investigate the effects of fermentation on bioactive compounds,antioxidant activity,and flavor characteristics of Artemisia argyi fermentation liquid(AAFL-LP)by an autochthonous strain,Lactiplantibacillus plantarum WLPL01.L.plantarum WLPL01 was found to utilize sugars and flavonoids to produce abundant organic acids,such as lactic acid and malic acid,improve antioxidant activity of Artemisia argyi including total superoxide dismutase content,1,1-diphenyl-2-picrylhydrazyl(DPPH)radical-scavenging capacity,and Fe-reducing antioxidant power,decrease largely bitter taste notes such as leucine,isoleucine,and phenylalanine,and enhance fruity,sweet,and flora notes such as terpenes and esters of AAFL-LP.Collectively,L.plantarum WLPL01 could improve the functionality of A.argyi and the flavor of the product,suggesting it a promising candidate in developing functional A.argyi food. 展开更多
关键词 Artemisia argyi Lactiplantibacillus plantarum wlpl01 Fermentation Antioxidant capacity Bioactive compounds
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