Background It is well known that dehydration can impair bodily functions. To evaluate the impact of hydration status under ambient environmental temperature on the immune system, 25 male collegiate wrestlers were recr...Background It is well known that dehydration can impair bodily functions. To evaluate the impact of hydration status under ambient environmental temperature on the immune system, 25 male collegiate wrestlers were recruited to undergo an experimental dehydration program.Methods Thirteen subjects had controlled diets with individual energy requirements to prevent body mass loss and restricted water intake to cause 4.52% dehydration; they formed the dehydrated group （DE）. These subjects developed a urine specific gravity of about 1.030 in 84 hours. Twelve other subjects had no water restriction and maintained their total body weight comprised the euhydrated group （EU）. Peripheral blood monocytes （PBMNC） were isolated after dehydration to perform immune response testing by being incubated with a polysaccharide fraction from fu-ling, Poria cocos （polysaccharide fraction from Poria cocos, PCPS, 1-30 μg/L）, to prepare a conditioned medium termed conditioned medium of PBMNC stimulated by PCPS （PCPS-MNC-CM）. More PCPS （25 μg/L） was needed in the DE group to prepare the PCPS-MNC-CM, which was assayed with a growth inhibitory curve for treated U973 cells.Results The treated U937 cells, incubated together with PCPS-MNC-CM from the DE group, exhibited a much lower nitroblue tetrazolium （NBT） positive value of （63.7±4.7）%. The concentration of interferon-gamma （IFN-Y）, interleukin （IL）-1β and tumor necrosis factor （TNF）-α in PCPS-MNC-CM from subjects after dehydration was much lower than in the CM from the EU group.Conclusion The immune response to PCPS in the DE group was lower than in normally hydrated subjects.展开更多
Most mediastinal abscesses result from infections after thoracotomy, esophageal perforation or pene- trating chest trauma. This disease is rarely caused by closed blunt chest trauma. All previously reported such cases...Most mediastinal abscesses result from infections after thoracotomy, esophageal perforation or pene- trating chest trauma. This disease is rarely caused by closed blunt chest trauma. All previously reported such cases after closed blunt chest trauma presented with hematoma and sternal osteomyelitis resulting from sternal fracture. Here we report a 15-year-old sumo wrestler who presented with an anterior mediastinal abscess without any mediastinal fracture. The mediastinal abscess resulted from the he- matogenous spread of Staphylococcus aureus to a hematoma that might have been caused by a closed blunt chest trauma incurred during sumo wrestling exercises.展开更多
THE Chinese like to say: "A person who does not worry does not grow up." It means that a mature person will always take a more realistic view of the future and not be blindly optimistic. "If there used ...THE Chinese like to say: "A person who does not worry does not grow up." It means that a mature person will always take a more realistic view of the future and not be blindly optimistic. "If there used to be a yard of difference between foreign countries and us, it’s only three展开更多
文摘Background It is well known that dehydration can impair bodily functions. To evaluate the impact of hydration status under ambient environmental temperature on the immune system, 25 male collegiate wrestlers were recruited to undergo an experimental dehydration program.Methods Thirteen subjects had controlled diets with individual energy requirements to prevent body mass loss and restricted water intake to cause 4.52% dehydration; they formed the dehydrated group （DE）. These subjects developed a urine specific gravity of about 1.030 in 84 hours. Twelve other subjects had no water restriction and maintained their total body weight comprised the euhydrated group （EU）. Peripheral blood monocytes （PBMNC） were isolated after dehydration to perform immune response testing by being incubated with a polysaccharide fraction from fu-ling, Poria cocos （polysaccharide fraction from Poria cocos, PCPS, 1-30 μg/L）, to prepare a conditioned medium termed conditioned medium of PBMNC stimulated by PCPS （PCPS-MNC-CM）. More PCPS （25 μg/L） was needed in the DE group to prepare the PCPS-MNC-CM, which was assayed with a growth inhibitory curve for treated U973 cells.Results The treated U937 cells, incubated together with PCPS-MNC-CM from the DE group, exhibited a much lower nitroblue tetrazolium （NBT） positive value of （63.7±4.7）%. The concentration of interferon-gamma （IFN-Y）, interleukin （IL）-1β and tumor necrosis factor （TNF）-α in PCPS-MNC-CM from subjects after dehydration was much lower than in the CM from the EU group.Conclusion The immune response to PCPS in the DE group was lower than in normally hydrated subjects.
文摘Most mediastinal abscesses result from infections after thoracotomy, esophageal perforation or pene- trating chest trauma. This disease is rarely caused by closed blunt chest trauma. All previously reported such cases after closed blunt chest trauma presented with hematoma and sternal osteomyelitis resulting from sternal fracture. Here we report a 15-year-old sumo wrestler who presented with an anterior mediastinal abscess without any mediastinal fracture. The mediastinal abscess resulted from the he- matogenous spread of Staphylococcus aureus to a hematoma that might have been caused by a closed blunt chest trauma incurred during sumo wrestling exercises.
文摘THE Chinese like to say: "A person who does not worry does not grow up." It means that a mature person will always take a more realistic view of the future and not be blindly optimistic. "If there used to be a yard of difference between foreign countries and us, it’s only three
