Anti-tumor Effect and Protective Effect on Chemotherapeutic Damage of Water Soluble Extracts from Hedyotis diffusa

Bai-Hua-She-She-Cao Hedyotis diffusa Willd. (Ru-biaceae) is a medicinal herbwidely distributed in northeast Asian countries. In traditional Chinese medicine, it has the effectof 'clearing away heat and toxic material, promoting blood circulation and removing blood stasis'.It is a well known Chinese folk-medicine used for the treatment of appendicitis, sore throat, mumps,acne, sebo-rheic dermatitis and various kinds of tumors, such as tumors of digestive tract,carcinoma of liver. It was reported that the MeOH extract of H. diffusa demonstrated a significantantitumor activity and ursolic acid succeeded in being isolated from the MeOH extract as an activecomponent . Shan BN, et al suggested that the direct aqueous extract of H. diffusa hadimmuno-modulating activity and antitumor activity in vitro through stimulating the immune system tokill or engulf tumor cells. But regarding anti-tumor activity in vivo of water soluble extracts fromH. diffusa, no detail was reported. Therefore, we prepared water soluble extracts (H_1 and H_2)from H. diffusa and evaluated their anti-tumor property in vivo experiments as well as protectiveeffect on chemo-therapeutic damage.

Biodegradability of soil water soluble organic carbon extracted from seven different soils

Water soluble organic carbon （WSOC） is considered the most mobile and reactive soil carbon source and its characterization is an important issue for soil ecology study. A biodegradability test was set up to study WSOC extracted from 7 soils differently managed. WSOC was extracted from soil with water （soil/water ratio of 1：2, W/V） for 30 min, and then tested for biodegradability by a liquid state respirometric test. Result obtained confirmed the finding that WSOC biodegradability depended on the both land use and management practice. These results suggested the biodegradability test as suitable method to characterize WSOC, and provided useful information to soil fertility.

Study on the Rapid Method to Predict Longevity of Controlled Release Fertilizer Coated by Water Soluble Resin

The study discussed the rapid method to test and predict the longevity of controlled release fertilizers （CRFs） coated by water soluble resin by using the short-term leaching under higher temperature. Pure water dissolving incubation and higher temperature leaching were used to study the patterns of the nutrient release of the CRFs. The correlation analysis between the days at 25℃ and the hours at 80℃ of Trincote 1 and Trincote 2 for the same cumulative release rates were conducted. Patterns of cumulative nutrient release curve followed one factor quadratic regression equation at each given temperatures, and each of relative coefficient was bigger than 0.995. As the temperature increased, nutrients release of the CRFs increased. The longevity of resin coated CRFs were predicted by use of both the cumulative nutrients release equation at 80℃ and the regression equation of release time needed for the same cumulative release rates between 25 and 80℃. There were only 0.3-6.9% relative errors between the tested longevity and predicted one. In conclusion, the longevity of resin coated CRFs could be predicted more quickly and precisely by use of the higher temperature short-term leaching method than that of the traditional differential release rate. The longevity of resin coated CRF could be rapidly and precisely predicted in a few hours by application of the higher temperature shortterm leaching method.

Improvement of humidity resistance of water soluble core by precipitation method

Water soluble core has been widely used in manufacturing complex metal components with hollow configurations or internal channels;however,the soluble core can absorb water easily from the air at room temperature.To improve the humidity resistance of the water soluble core and optimize the process parameters applied in manufacturing of the water soluble core,a precipitation method and a two-level-three-full factorial central composite design were used,respectively.The properties of the cores treated by the precipitation method were compared with that without any treatment.Through a systematical study by means of both an environmental scanning electron microscope(ESEM) and an energy dispersive X-ray(EDX) analyzer,the results indicate that the hygroscopicity can be reduced by 20% and the obtained optimal process conditions for three critical control factors affecting the hygroscopicity are 0.2 g·mL-1 calcium chloride concentration,4% water concentration and 0 min ignition time.The porous surface coated by calcium chloride and the high humidity resistance products generated in the precipitation reaction between calcium chloride and potassium carbonate may contribute to the lower hygroscopicity.

PREPARATION AND PHOTOSENSITIVITY OF WATER SOLUBLE PHENOLIC RESINS CONTAINING ACRYLOYL AND QUATERNARY AMMONIUM CHLORIDE GROUPS

New water soluble and photocrosslinkable prepolymers containing acrylate and quaternary ammonium salt groups were synthesized from epoxy phenolic resin via ring-opening reaction with acrylic acid and with aqueous solution of triethylamine hydrochloride successively. The second reaction needs no phase transfer catalyst to accelerate, since the product formed can act as a phase transfer catalyst. The prepolymer obtained contains both photocrosslinkable acrylate groups and hydrophilic quaternary ammonium salt groups. Optimum conditions for these reactions were studied. The photosensitivity of the prepolymer was also investigated. The effects of different photoinitiators, different crosslinkable diluent monomers and amine accelerator on the photosensitivity of the prepolymer were compared. The photoinitiator of hydrogen abstraction type is still effective without using amine or alcohol as accelerator, because the prepolymer contains a H beside the OH groups formed in the ring-opening reactions.

Partitioning of water soluble organic carbon in three sediment size fractions:Effect of the humic substances

Water soluble organic carbon （WSOC） in sediments plays an important role in transference and transformation of aquatic pollutants. This article investigated the inherent mechanisms of how sediemnt grain size affect the partitioning coeffcient （k） of WSOC. Influences of NaOH extracted humic substances were particularly focused on. Sediments were sampled from two cross-sections of the middle Yellow River and sieved into three size fractions （〈 63 μm, 63-100 μm, and 100-300 μm）. The total concentration of WSOC in sediments （Cwsoc） and k were estimated using multiple water-sediment ratio experiments. Results showed that Cwsoc ranged from 0.012 to 0.022 mg/g, while k ranged from 0.8 to 3.9 L/kg. Correlations between the spectrum characteristics of NaOH extracted humic substances and k were analyzed. Strong positive correlations are determined between k and the aromaticity indicators of NaOH extracted humic substances in different sediment size fractions. Comparing with finer fractions （〈 63 μm）, k is higher in larger size fractions （63- 100 μm and 100-300 μm） related to higher aromaticity degree of NaOH extracted humic substances mostly. While negative relationship between k and the area ratio of fourier transform infrared spectroscopy （FT-IR） at 3400 and 1430 cm^-1 implied that the lowest k was related to the highest concentration of acidic humic groups in particles 〈 63 μm. WSOC in finer fractions （〈 63 μm） is likely to enter into pore water, which may further accelerate the transportation of aquatic contaminants from sediment to water.

Fluorescence characteristics of water soluble organic carbon in eastern China

Fluorescence excitation and average molecular weight of 46 water soluble organic matter (WSOC) samples extracted from 20 soil types in eastern China were determined. It was found all samples shared similar spectroscopy. A good linear relationship existed between total organic carbon and excitation in the range of 350 to 450 nm though the content of organic carbon and pH of the samples vary in a wide range. No significant correlation between relative excitation intensity and average molecular weight of WSOC and FA was found, but the partial correlation became significant with pH as the controlling factor for WSOC samples. The relative excitation intensity showed a general trend of increasing from south to north in the study area. The pH value might play an important role in regulating the fluorescent spatial variation of WSOC. S153 A

The Preparation of 2-O-Acetonyl-β-cyclodextrin as One Key Intermediate for Water Soluble β-Cyclodextrin Derivatives

O-Acetonyl-b-cyclodextrin with a suitable average substitution degree of about 5.8, which could be used as a key intermediate for water soluble functional b-cyclodextrin derivatives, was prepared based on the proper oxidation of heptakis (6-O-dimethyl-tert-butylsilyl)-2-O -hydroxypropyl-b-cyclodextrin.

STRUCTURAL STUDIES OF AN ARABINOGALACTAN——A WATER SOLUBLE POLYSACCHARIDE FROM THE POLLEN OF PAPAVER SOMNIFERUM

A polysaccharide,PS(1),has been isolated from the pollen of papaver somniferum.PS(1)is a highly branched arabinogalactan,which,mainly contains α—L—arabinofuranosyl(1→)and(3,6→1)— β—D—galactopyranosyl residues.We also studied the circular dichroism and immunoactivity of PS(1).

WATER SOLUBLE DISPERSE DYES CONTAINING CARBOXY-METHYL-SULFONYL GROUP

Water soluble disperse dyes of either monoazo or anthraquinone types containing the carboxymethylsulfonylgroup（-SO2CH2COOH）were synthesized.Ammonium salts of this type of dyes are more soluble thanother salts.These dyes are suitable for pad dyeing or printing on polyester fiber and polyester/cottonblends in either weak acid,neutral or weak alkali medium without a dispersing agent.The formation of-SO2CH3 group from -SO2CH2COOH group after fixing on the fiber was proved.

THE STUDY ON THE WATER SOLUBLE PEPTIDES IN PAPAVER SOMNIFERUM POLLEN EXTRACTION,PURIFICATION,SEQUENCE DETERMINATION AND SYNTHESIS

Four peptides PSPP1,PSPP2,PSPP3 and PSPP4 were purified from the water-extract of Papaver somniferum pollen.Their sequences,with 21,17,13 and 16 amino acid residues respectively,have been determined by Edman degradation-N-terminal dansylation.PSPP2, PSPP3 and PSPP4 were synthesized using solid phase method.The immunopromotive activities of PSPP1,PSPP2,PSPP3,PSPP4 and the initially separated sample PSPP have been also observed by the methods of counting erythrocyte rosette forming cells(ERFC) and T-lymphocyte transformation test in vitro.

CARBOXYMETHYLPACHYMAN(Ⅰ),A NEW WATER SOLUBLE POLYSACCHARIDE WITH MARKED ANTITUMOUR ACTIVITY

Carboxymethylpachyman(Ⅰ)was formed by carboxymethylation of β-pachyman.The antitumour activity of carboxymethylpachyman(Ⅰ)against S_(180)、EAC、 MA、U_(14)was measured.The structure of carboxymethylpachyman(Ⅰ)was proved by IR ^(13)CNMR spectroscopy.

SYNTHESIS AND PARTIAL CHARACTERIZATION OF WATER SOLUBLE RAPE POLLEN DODECAPEPTIDE

A dodecapeptide extracted from rape pollen was synthesized using solid—phase method,its conforma- tions in different states were studied by FT—IR,CD,and its physiological activities were determined.Seven segments and five analogs were also synthesized to elucidate the structure—function relation.

Experiment of Water Soluble Fertilizers Containing Humic Acid in Tomato Planting

As a natural macromolecular organic compound,humic acid can promote plant growth.Water soluble humic acid fertilizers refer to liquid or solid water soluble fertilizers made by adding appropriate amounts of nitrogen,phosphorus,potassium macroelements or zinc,boron,iron,molybdenum,manganese,copper and other trace elements or organic matter,based on humic acid in the required proportions for plant growth.In order to verify the application effect of humic acid containing water soluble fertilizer produced by Tai’an Gold Land Chemical Co.,Ltd.,in tomato production in Daiyue District,Tai’an City,a fertilizer effect application experiment of humic acid containing water soluble fertilizer on tomato planting was specially carried out.The results showed that the water soluble fertilizer containing humic acid could obviously improve the agronomic characters of tomato;the yield was significantly increased;the effect of increasing the income of tomato growers was obvious.

NOVEL WATER SOLUBLE HOST MOLECULE DERIVED FROM CALIXARENE

Reaction of p-t-butylcalix[6]arene with ethylene oxide gives a water soluble host compound with a hydrophobic cavity and it can include organic molecules and ions in aqueous solution.

Effect of Different Levels of Water Soluble Phosphorus in Complex Fertilizers on Crop Productivity and Soil Health

Field experiments were undertaken on sandy soils with three cropping systems at Giridih,Jharkhand,India for two years during 2012-2014.The experiments were executed in split plot design by assigning water soluble phosphorus(WSP)fertilizers in main-plot and recommended dose of phosphorus(RDP)in sub-plot with three replications.The maximum economical yield of rice(4705 kg/ha),baby corn(842 kg/ha)and Chickpea(920 kg/ha)were recorded with the application of 30%WSP.The maximum economical yield of successive crops-wheat(3185 kg/ha),mustard(1720 kg/ha)and groundnut(1578 kg/ha)were recorded with the application of 30%WSP and 100%RDP treatment.Almost similar trends were noticed in terms of by-product yield,nutrient uptake and residual soil fertility status.All the levels of WSP(30%-89%)in complex fertilizers were found to be equally effective for grain yield,straw yield,nutrient uptake,and residual soil fertility.

Response of antioxidase in viscera of Pagrosuma Major larvae to water soluble fraction of hydrocarbons in No.0 diesel oil

Pagrosomus major larvae were exposed to the water soluble fraction of hydrocarbon in No.0 diesel oil (corresponding to No.2 fuel oil) at concentrations of 0, 0 17, 1.22 and 8 82 mg/L for up to 15 days. Larvae were sampled on days 9 and l5 of the experiment. Supernatants of viscera tissue extractions were assayed for biochemical response in terms of oxidative stress superoxide dismutase(SOD), activity of selenium dependant glutathione peroxidase(Se GPx) and catalase(Ca), and the concentration of reduced glutathione(GSH). On day 9 of exposure, statistically significant dose related increases in Se GPx and SOD activity, and GSH concentration were observed in all cases except for Se GPx activity under the highest dosage of hydrocarbon. However, on day l5 of exposure, a similar dose related response was only observed for Se GPx activity. GSH concentration decreased and SOD activity showed no statistical difference as compared to controls. However, a significant decrease in compared to day 9 Se GPx activity and GSH concentration, in contrast to increase SOD activity at day 15 as indicates an accelerated accumulation of H 2O 2 and potential oxidative damage under long term exposure of larvae to hydrocarbons. No statistical changes were observed in Ca activity throughout the experiment, possibly owing to the high efficiency of Se GPx. A recovery experiment was performed on indicating that the response of antioxidants measured tending to return to their control levels. These results prove the function of the antioxidant defense system of the larvae to the water soluble fraction of hydrocarbons in No.0 diesel oil.

A strategy based on water soluble coal tar pitches to construct MnO_(2)@C composite materials with high electrochemical performance

The water soluble coal tar pitches(WS-CTPs)were successfully prepared and used to construct the MnO_(2)@C composite materials by a hydrothermal method.It is interestingly observed that the structures and morphologies of MnO_(2)@C materials can be controlled by controlling the dosages of WS-CTPs and KMnO4.Meanwhile,it is aware that MnO_(2)exists in the MnO_(2)@C materials in an amorphous state.Compared with MnO_(2),MnO_(2)@C materials output a remarkable improvement in electrochemical performance.For instance,MnO_(2)@C-0.3 shows the storage capacity at 965.7 mA h g^(−1)after 300 cycles at a current density of 0.1 A g^(−1).In addition,after 600 cycles at a current density of 1.0 A g^(−1),the storage capacity of MnO_(2)@C-0.3 still keeps 450.3 mA h g^(−1),indicating that MnO_(2)@C-0.3 owns tremendous cycle stability at a high current density.In view of the fact that the coal tar pitches possess great cost advantages,the strategy of using WS-CTPs as a carbon source to cover the metal oxides is a competitive way to expand the application of metal oxides in the fabrication of electrodes of LIBs.

Photocatalytic Degradation of Water-Soluble Dyes by LaCoO_3

Pervoskite type oxides LaCoO 3 was prepared by citrate method with the granula of 20 nm-30 nm. With a fluorescent Hg lamp or sunlight as irradiator, the degradation experiments of various water soluble dyes were carried out in the suspension system of LaCoO 3 . The results show that the pervoskite type oxide LaCoO 3 has good photocatalytic activity.Studied by X ray photoelectron spectroscopy and photoacoustic spectra, its photocatalytic activity is found to be related with factors such as the d electron structure of ion Co 3+ ,Co—O binding energy and adsorbed oxygen on the surface etc.

Water Soluble Gas in Deep Carbonate Reservoir, Sichuan Basin, Southwest China

Based on temperature and pressure of fluid inclusion, phase of organic inclusion in calcite and quartz filled in vug in the deep carbonate reservoir and the natural gas composition in Weiyuan （威远） gas field in Sichuan （四川） basin, research indicates that water soluble gas exists in deep carbonate reservoir, which reconstructs development and effusion process of water soluble gas. The overpressure formed during oil thermal cracking can reach 105-170 MPa in Sinian and Cambrian reservoir in Central Sichuan and 78-86 MPa in Cambrian reservoir in Southeast Sichuan. The high temperature caused by deep burial and overpressure caused by thermal cracking make thermal cracking gas dissolve in water so that it becomes water soluble gas. The ratios of gas to water can reach 50-90 m^3/m^3 and 10-30 m^3/m^3, respectively, in deep carbonate reservoir in Central and Southeast Sichuan. Methane dissolving in water exists in form of liquid phase. Until now, the decreases in temperature and pressure due to the uplift during 74 Ma make water soluble gas separate from water, water soluble gas pool or mixed gas pool of thermal-cracking gas and water soluble gas are modified or even destroyed in varying degrees.This may be the case of Weiyuan gas field.