Study on Free-Standing Riser Under Different Working Conditions Based on 3D Co-Rotational Beam Element

When the free standing riser(FSR)is in service in the ocean,its mechanical properties are affected by various factors,including complex ocean current forces,buoyancy of the buoyancy can,and torque caused by the deflection of the upper floating body.These loads have a great influence on the deformation and internal force of the FSR.The static performance of FSR is investigated in this research under various working conditions.The finite element model of FSR is established based on the co-rotational method.The arc length approach is used to solve the model.The load is exerted in increments.The current load on the riser changes with the configuration of the riser.The accuracy of the numerical method is verified by Abaqus software.The calculation time is also compared.Then,the effects of uniform current,actual current and floating body yaw motion on FSR are studied by parameter analysis.Additionally,the influence of the FSR on the ocean current after the failure of part of the buoyancy can chamber is analyzed.The results show that the numerical model based on the co-rotational method can effectively simulate the large rotation and torsion behavior of FSR.This method has high computational efficiency and precision,and this method can quickly improve the efficiency of numerical calculation of static analysis of deep-water riser.The proposed technology may serve as an alternative to the existing proprietary commercial software,which uses a complex graphical user interface.

Effects of Standing Time during Pretreatment on the Nitrite Concentration Detected by Spectrophotometric Method

Food safety problems caused by excessive nitrite addition have been frequently reported and the detection of nitrite in food is particularly important. The standing time during the pretreatment of primary sample has a great influence on the concentration of nitrite tested by spectrophotometric method. In this context, three kinds of food samples are prepared, including canned mustard, canned fish and home-made pickled water. A series of standing times are placed during the sample pretreatments and the corresponding nitrite contents in these samples are detected by spectrophotometric method based on N-ethylenediamine dihydrochloride. This study aims to find out a reasonable standing time during the pretreatment of food sample, providing influence factor for precise detection of nitrite.

Existence and Stability of Standing Waves for the Nonlinear Schrödinger Equation with Combined Nonlinearities and a Partial Harmonic Potential

In this paper, we study the existence of standing waves for the nonlinear Schrödinger equation with combined power-type nonlinearities and a partial harmonic potential. In the L2-supercritical case, we obtain the existence and stability of standing waves. Our results are complements to the results of Carles and Il’yasov’s artical, where orbital stability of standing waves have been studied for the 2D Schrödinger equation with combined nonlinearities and harmonic potential.

Assessing cutter-rock interaction during TBM tunnelling in granite:Large-scale standing rotary cutting tests and 3D DEM simulations

The widespread utilisation of tunnel boring machines(TBMs)in underground construction engineering requires a detailed investigation of the cutter-rock interaction.In this paper,we conduct a series of largescale standing rotary cutting tests on granite in conjunction with high-fidelity numerical simulations based on a particle-type discrete element method(DEM)to explore the effects of key cutting parameters on the TBM cutter performance and the distribution of cutter-rock contact stresses.The assessment results of cutter performance obtained from the cutting tests and numerical simulations reveal similar dependencies on the key cutting parameters.More specifically,the normal and rolling forces exhibit a positive correlation with penetration but are slightly influenced by the cutting radius.In contrast,the side force decreases as the cutting radius increases.Additionally,the side force shows a positive relationship with the penetration for smaller cutting radii but tends to become negative as the cutting radius increases.The cutter's relative effectiveness in rock breaking is significantly impacted by the penetration but shows little dependency on the cutting radius.Consequently,an optimal penetration is identified,leading to a low boreability index and specific energy.A combined Hertz-Weibull function is developed to fit the cutter-rock contact stress distribution obtained in DEM simulations,whereby an improved CSM(Colorado School of Mines)model is proposed by replacing the original monotonic cutting force distribution with this combined Hertz-Weibull model.The proposed model outperforms the original CSM model as demonstrated by a comparison of the estimated cutting forces with those from the tests/simulations.The findings from this work that advance our understanding of TBM cutter performance have important implications for improving the efficiency and reliability of TBM tunnelling in granite.

Fabrication of Free Standing Nanocellulose Film via Spray Coating and its Biomedical Application: A Review

Spraying nanocellulose onto films provides a quick and scalable way to create free-standing films with exceptional consistency and customizable thickness. This method increases the application of nanocellulose films in various industries and satisfies the requirements of large-scale production. In the field of biomedicine, spray-coated free-standing nanocellulose films hold great promise for applications such as drug delivery, tissue engineering, wound healing, device coatings, and biosensing. They are excellent nanomaterials for a variety of biomedical applications due to their special qualities, including biocompatibility, high mechanical strength, porous structure, large surface area, and adaptability. This paper reviewed the detailed exposure of the spray coating process of nanocellulose suspension onto free- standing films and its biomedical applications.

Long-term hydrochemical monitoring and geothermometry:understanding groundwater salinization and thermal fluid contamination in Mila’s basin,Northeastern Algeria

The regular hydrochemical monitoring of groundwater in the Mila basin over an extended period has provided valuable insights into the origin of dissolved salts and the hydrogeochemical processes controlling water salinization.The data reveals that the shallow Karst aquifer shows an increase in TDS of 162 mg L^(-1) while the ther-mal carbonate aquifer that is also used for drinking water supply exhibits an increase of 178 mg L^(-1).Additionally,significant temperature variations are recorded at the sur-face in the shallow aquifers and the waters are carbo-gaseous.Analysis of dissolved major and minor elements has identified several processes influencing the chemical composition namely:dissolution of evaporitic minerals,reduction of sulphates,congruent and incongruent car-bonates’dissolution,dedolomitization and silicates’weathering.The hydrogeochemical and geothermometric results show a mixing of saline thermal water with recharge water of meteoric origin.Two main geothermalfields have been identified,a partially evolved water reservoir and a water reservoir whosefluid interacts with sulphuric acid(H_(2)S)of magmatic origin.These hot waters that are char-acterized by a strong hydrothermal alteration do ascend through faults and fractures and contribute to the contamination of shallower aquifers.Understanding the geothermometry and the hydrogeochemistry of waters is crucial for managing and protecting the quality of groundwater resources in the Mila basin,in order to ensure sustainable water supply for the region.A conceptual model for groundwater circulation and mineralization acquisition has been established to further enhance under-standing in this regard.

Understanding the Global Identification with China’s Stories: A Cross-Cultural Perspective

Cross-cultural storytelling is a primary way for humankind to seek mutual recognition of value orientations between cultures,which facilitates the ability to jointly address the problems of human existence in the context of globalization.In this study,we conducted an interview survey of 6,130 respondents who were college students or graduates from 107 countries.The results show that there were a number of cross-cultural values embodied in China’s stories seen by the respondents as part of a common vision for the future of humankind and widely identified guidance on collaborative responses to global challenges.These cross-cultural values are common prosperity,ecological harmony,individual-collective integration,the urgency of global peace,as well as respect for multicultural and indigenous development paths.

Glycolytic dysregulation in Alzheimer's disease:unveiling new avenues for understanding pathogenesis and improving therapy

Alzheimer's disease poses a significant global health challenge owing to the progressive cognitive decline of patients and absence of curative treatments.The current therapeutic strategies,primarily based on cholinesterase inhibitors and N-methyl-Daspartate receptor antagonists,offer limited symptomatic relief without halting disease progression,highlighting an urgent need for novel research directions that address the key mechanisms underlying Alzheimer's disease.Recent studies have provided insights into the critical role of glycolysis,a fundamental energy metabolism pathway in the brain,in the pathogenesis of Alzheimer's disease.Alterations in glycolytic processes within neurons and glial cells,including microglia,astrocytes,and oligodendrocytes,have been identified as significant contributors to the pathological landscape of Alzheimer's disease.Glycolytic changes impact neuronal health and function,thus offering promising targets for therapeutic intervention.The purpose of this review is to consolidate current knowledge on the modifications in glycolysis associated with Alzheimer's disease and explore the mechanisms by which these abnormalities contribute to disease onset and progression.Comprehensive focus on the pathways through which glycolytic dysfunction influences Alzheimer's disease pathology should provide insights into potential therapeutic targets and strategies that pave the way for groundbreaking treatments,emphasizing the importance of understanding metabolic processes in the quest for clarification and management of Alzheimer's disease.

Zeno and the Wrong Understanding of Motion—A Philosophical-Mathematical Inquiry into the Concept of Finitude as a Peculiarity of Infinity

In contrast to the solutions of applied mathematics to Zeno’s paradoxes, I focus on the concept of motion and show that, by distinguishing two different forms of motion, Zeno’s apparent paradoxes are not paradoxical at all. Zeno’s paradoxes indirectly prove that distances are not composed of extensionless points and, in general, that a higher dimension cannot be completely composed of lower ones. Conversely, lower dimensions can be understood as special cases of higher dimensions. To illustrate this approach, I consider Cantor’s only apparent proof that the real numbers are uncountable. However, his widely accepted indirect proof has the disadvantage that it depends on whether there is another way to make the real numbers countable. Cantor rightly assumes that there can be no smallest number between 0 and 1, and therefore no beginning of counting. For this reason he arbitrarily lists the real numbers in order to show with his diagonal method that this list can never be complete. The situation is different if we start with the largest number between 0 and 1 (0.999…) and use the method of an inverted triangle, which can be understood as a special fractal form. Here we can construct a vertical and a horizontal stratification with which it is actually possible to construct all real numbers between 0 and 1 without exception. Each column is infinite, and each number in that column is the starting point of a new triangle, while each row is finite. Even in a simple sine curve, we experience finiteness with respect to the y-axis and infinity with respect to the x-axis. The first parts of this article show that Zeno’s assumptions contradict the concept of motion as such, so it is not surprising that this misconstruction leads to contradictions. In the last part, I discuss Cantor’s diagonal method and explain the method of an inverted triangle that is internally structured like a fractal by repeating this inverted triangle at each column. The consequence is that we encounter two very different methods of counting. Vertically it is continuous, horizontally it is discrete. While Frege, Tarski, Cantor, Gödel and the Vienna Circle tried to derive the higher dimension from the lower, a procedure that always leads to new contradictions and antinomies (Tarski, Russell), I take the opposite approach here, in which I derive the lower dimension from the higher. This perspective seems to fail because Tarski, Russell, Wittgenstein, and especially the Vienna Circle have shown that the completeness of the absolute itself is logically contradictory. For this reason, we agree with Hegel in assuming that we can never fully comprehend the Absolute, but only its particular manifestations—otherwise we would be putting ourselves in the place of the Absolute, or even God. Nevertheless, we can understand the Absolute in its particular expressions, as I will show with the modest example of the triangle proof of the combined horizontal and vertical countability of the real numbers, which I developed in rejection of Cantor’s diagonal proof. .

Soil properties and not plant factors affect both abundant and rare microbial taxa after thinning in a mixed stand of Cunninghamia lanceolata and Sassafras tzumu

Thinning is an effective management step for sustainable forest development,yet less attention is paid to the restoration of soil microbiota after thinning.In this study,both abundant and rare soil microbial communities(i.e.,bacterial,fungal),were evaluated under various thinning treatments in a mixed stand of Cunninghamia lanceolata and Sassafras tzumu using Mi Seq sequencing.Thinning did not significantly change either abundant or rare bacterial and fungal community composition,but affected their alpha diversity.The Shannon–Wiener indexes of rare fungal taxa under medium thinning were significantly lower than in the light thinning(P<0.05 level).Xanthobacteraceae dominated the abundant bacterial taxa,and Saitozyma and Mortierlla the abundant fungal taxa.The most common rare bacterial taxa varied;there was no prevalent rare fungal taxa under different thinnings.In addition,soil available nitrogen,total phosphorus,and p H had significant effects on rare bacterial taxa.Nutrients,especially available phosphorus,but not nitrogen,affected abundant and rare soil fungi.The results indicate that soil properties rather than plant factors affect abundant and rare microbial communities in soils of mixed stands.Thinning,through mediating soil properties,influences both abundant and rare bacterial and fungal communities in the mixed C.lanceolata and S.tzumu stand.

Impact of cattle density on the structure and natural regeneration of a turkey oak stand on an agrosilvopastoral farm in central Italy

On an agrosilvopastoral farm in central Italy where Maremmana cattle graze in Turkey oak forests,we evaluated the impact of different livestock densities on stand structure,tree diversity and natural regeneration in four types of grazed areas based on the grazing regime adopted:calf-grazed,high-intensity-grazed,low-intensity-grazed,ungrazed control.For each area,we set up three permanent circular plots(radius of 15 m)to survey the structural and dasometric characteristics of the overstorey,understorey,and regeneration layer.The results showed that grazing negatively affected the complexity of the forest structure and its potential to regenerate and maintain a high level of biodiversity.The differences in stand structure observed between the grazing areas were closely related to livestock density.The most sensitive components of the system were the understorey and the regeneration layers.Contrarily,the current grazing management did not affect the dominant tree structure or its composition.Our findings identified medium-term monitoring and regeneration management as the two significant aspects to consider when assessing sustainable livestock.New forests can be established by excluding graz-ing for about 20–25 years.

Simulation of Haloxylon Ammodendron Stand Basic Diameter Structure Based on Fuzzy Distribution Function

Based on the investigation data of 12 Haloxylon ammodendron plots in the south edge of Gurbantunggut Desert, Fuzzy distribution was introduced into the study of Haloxylon ammodendron base diameter structure fitting according to the consistency between the characteristics of Fuzzy distribution function and the distribution series of cumulative percentage of stand base diameter, and the fitting precision and effect of Fuzzy distribution function were discussed. The root mean square error RMSE and determination coefficient R2 values showed that Fuzzy-Γ1, Fuzzy-Γ2, Fuzzy-Γ3, Fuzzy-Γ4 had good fitting performance, among which Fuzzy-Γ1 had relatively high fitting precision, and its parameters were closely related to stand age and density, Fuzzy-Γ2 distribution function was the second, and Fuzzy-Γ4 distribution function had the worst fitting effect. By introducing a parameter c from the similarity of four distribution function formulas, a generalized Fuzzy distribution function Fuzzy-Γ5 is obtained. This function shows the highest fitting accuracy. Most of the values of parameter c are near 1 or 2, which shows that the diameter distribution is mainly approximate to Fuzzy-Γ1 and Fuzzy-Γ2.

The effects of data aggregation on long-term projections of forest stands development

Forest management planning often relies on Airborne Laser Scanning(ALS)-based Forest Management Inventories(FMIs)for sustainable and efficient decision-making.Employing the area-based(ABA)approach,these inventories estimate forest characteristics for grid cell areas(pixels),which are then usually summarized at the stand level.Using the ALS-based high-resolution Norwegian Forest Resource Maps(16 m×16 m pixel resolution)alongside with stand-level growth and yield models,this study explores the impact of three levels of pixel aggregation(standlevel,stand-level with species strata,and pixel-level)on projected stand development.The results indicate significant differences in the projected outputs based on the aggregation level.Notably,the most substantial difference in estimated volume occurred between stand-level and pixel-level aggregation,ranging from-301 to+253 m^(3)·ha^(-1)for single stands.The differences were,on average,higher for broadleaves than for spruce and pine dominated stands,and for mixed stands and stands with higher variability than for pure and homogenous stands.In conclusion,this research underscores the critical role of input data resolution in forest planning and management,emphasizing the need for improved data collection practices to ensure sustainable forest management.

Runoff Characteristics of Different Stands in Dongjiang Lake Reservoir Area

Different forest stands in the Dongjiang Lake Reservoir area of Zixing were selected as the research objects to study the characteristics of runoff generation in different forest stands.The results showed that there was no significant difference in annual runoff among M3,M1,and M5,and no significant difference between each forest stand and the control.The order was M3(22.75 mm)>M1(21.77 mm)>M5(20.14 mm).Forest vegetation generates less runoff through vegetation restoration compared to the control,indicating that forest vegetation reconstruction and restoration are beneficial for soil and water conservation.

Helical streamers guided by surface electromagnetic standing waves

The streamer that is driven by the specific pulse DC discharge parameters can stably form a three-dimensional helical plasma channel in a long dielectric tube in the low-temperature plasma experiment,in cases when there were neither external background magnetic field or other factors that destroyed the poloidal symmetry of the tube.The formation mechanism and chirality of helical streamers are discussed according to the surface electromagnetic standing wave theory.The shape of the helical streamers and the characteristics of helical branches are quantitatively analyzed to further expand the application of plasma and streamer theory in the helix problem and chiral catalytic synthesis.

Tunable vacancy defect chemistry on free-standing carbon cathode for lithium-sulfur batteries

The defect chemistry is successfully modulated on free-standing and binder-free carbon cathodes for highly efficient Li-S redox reactions.Such rationally regulated defect engineering realizes the synchronization of ion/electron-conductive and defect-rich networks on the threedimension carbon cathode,leading to its tunable activity for both relieving the shuttle phenomenon and accelerating the sulfur redox reaction kinetics.As expected,the defective carbon cathode harvests a high rate capacity of 1217.8 mAh g^(-1)at 0.2 C and a superior capacity retention of61.7%at 2 C after 500 cycles.Even under the sulfur mass loading of 11.1 mg cm^(-2),the defective cathode still holds a remarkable areal capacity of 8.5 mAh cm^(-2).

Uniaxial compressive behaviour of a FRP standing support made of mine wastes

Twenty-seven specimens were tested to investigate the uniaxial compression behaviour of an innovative standing support for underground space applications.The innovative standing support consisted of an external fibre reinforced polymer(FRP)jacket and the infill column made of cementitious grout,tailings and coal wash rejects.Effects of the FRP layers number and water to the cementitious grout(w/g)ratio were evaluated.Test results indicated that lower w/g ratios produced stronger infill columns.With FRP confinement,the standing support demonstrated strain-hardening loading characteristics with a significant improvement in both strength and ductility.The highest strength and strain of the specimens achieved was 58.4 MPa and 11.8%respectively.Compared with the unconfined specimens,the confinement with four FRP layers increased the specimen strength and associated strain up to 3.6 and 27.0 times respectively.A correlation between the compressive strength of the infill material and the ultrasonic pulse velocity was also investigated.Furthermore,a simple design-oriented model was proposed to predict the peak strength and the corresponding strain of the innovative standing support.

Surgical treatment of inflammatory bowel disease:From the gastroenterologist’s stand-point

Treatment of ulcerative colitis(UC)and Crohn’s disease(CD)represents,in the majority of cases,a real challenge to the gastroenterologist’s abilities and skills as well as a clinical test concerning his/her levels of medical knowledge and experience.During the last two decades,our pharmaceutical arsenal was significantly strengthened,especially after the introduction of the so-called biological agents,drugs which to a large extent not only improved the results of conservative treatment but also changed the natural history of the disease.However,colectomy is still necessary for some patients with severe UC although smaller compared to the past,precisely because of the improvements achieved in the available conservative treatment.Nevertheless,surgeries to treat colon dysplasia and cancer are increasing to some extent.At the same time,satisfactory improvements in surgical techniques,the pre-and post-operative care of patients,as well as the selection of the appropriate time for performing the surgery have been noticed.Regarding patients with CD,the improvement of conservative treatment did not significantly change the need for surgical treatment since two-thirds of patients need to undergo surgery at some point in the course of their disease.On the other hand,the outcome of the operation has improved through good preoperative care as well as the wide application of more conservative surgical techniques aimed at keeping as much of the bowel in situ as possible.This article discusses the indications for surgical management of UC patients from the gastroenterologist’s point of view,the results of the emerging new techniques such as transanal surgery and robotics,as well as alternative operations to the classic ileo-anal-pouch anastomosis.The author also discusses the basic principles of surgical management of patients with CD based on the results of the relevant literature.The self-evident is emphasized,that is,to achieve an excellent therapeutic result in patients with severe inflammatory bowel disease in today’s era;the close cooperation of gastroenterologists with surgeons,pathologists,imaging,and nutritionists is of paramount importance.

Advancing our understanding of monocyte HLA-DR,S100A9,and the potential for individualized therapies in sepsis

By def inition, sepsis refers to a life threatening organ dysfunction due to a dysregulated host response to an infection[1]. More precisely, sepsis triggers a multifaceted response characterized by a simultaneous manifestation of proinflammatory and anti-inflammatory elements that disrupt mechanisms intended to maintain homeostasis. Initially, an overwhelming hyperinflammatory reaction ensues, resulting in tissue damage and organ dysfunction.

Study of Quality Standards of Xiao’er Qingre Enema Preparation in Hospitals

Objective:To establish the quality standards for the preparation of Xiao’er Qingre enema in hospitals.Method:Thin-layer chromatography(TLC)was used to identify Radix Isatidis and Glycyrrhizae in the prescription.The content of(R,S)-Goitrin was determined by high-performance liquid chromatography(HPLC).Results:In TLC identification,there was no interference between the negative controls of Radix Isatidis and glycyrrhizae,and the spots were well-separated.The HPLC results of(R,S)-Goitrin showed a good linear relationship between the peak area and concentration within the range of 0.476-95.2μg·mL-1(r=0.9999).Conclusion:The TLC and HPLC methods established in this experiment are simple,reproducible,and specific,making them suitable for the quality control Xiao’er Qingre enema preparation in hospitals.